Published in Genetics on January 22, 2013
RNAi function, diversity, and loss in the fungal kingdom. Chromosome Res (2013) 0.90
Neurospora Heterokaryons with Complementary Duplications and Deficiencies in Their Constituent Nuclei Provide an Approach to Identify Nucleus-Limited Genes. G3 (Bethesda) (2015) 0.81
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
The genetics of Aspergillus nidulans. Adv Genet (1953) 18.50
Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans. Plant Cell (1990) 10.56
Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase. Nature (1999) 6.02
Small RNAs in transcriptional gene silencing and genome defence. Nature (2009) 5.98
Premeiotic instability of repeated sequences in Neurospora crassa. Annu Rev Genet (1990) 5.92
Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Adv Genet (1977) 5.43
Induction of a Highly Specific Antiviral State in Transgenic Plants: Implications for Regulation of Gene Expression and Virus Resistance. Plant Cell (1993) 4.68
Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA. Science (1997) 4.23
Meiotic silencing by unpaired DNA. Cell (2001) 3.48
On the origin and functions of RNA-mediated silencing: from protists to man. Curr Genet (2006) 3.05
Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. Am J Hum Genet (1997) 3.05
RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants. Plant Mol Biol (1996) 2.92
Listening to the silent genes: transgene silencing, gene regulation and pathogen control. Trends Plant Sci (1999) 2.83
Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa. Proc Natl Acad Sci U S A (1997) 2.69
Direct and indirect gene replacements in Aspergillus nidulans. Mol Cell Biol (1985) 2.61
3'-end-forming signals of yeast mRNA. Trends Biochem Sci (1996) 2.47
Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res (1993) 2.47
Mating types and sexual development in filamentous ascomycetes. Microbiol Mol Biol Rev (1997) 2.29
Epigenetic phenomena in filamentous fungi: useful paradigms or repeat-induced confusion? Trends Genet (1997) 2.24
Redundancy of the two dicer genes in transgene-induced posttranscriptional gene silencing in Neurospora crassa. Mol Cell Biol (2004) 2.10
Meiotic silencing by unpaired DNA: properties, regulation and suppression. Genetics (2002) 2.09
Evolution of the fungal self-fertile reproductive life style from self-sterile ancestors. Proc Natl Acad Sci U S A (1999) 1.97
Homology-dependent gene silencing in plants and fungi: a number of variations on the same theme. Curr Opin Microbiol (1999) 1.94
Transcriptional gene silencing in plants: targets, inducers and regulators. Trends Genet (2001) 1.92
The role of the RNAi machinery in heterochromatin formation. Cell (2005) 1.89
Developmental regulation of the Aspergillus nidulans trpC gene. Proc Natl Acad Sci U S A (1983) 1.88
Identification of the sex genes in an early diverged fungus. Nature (2008) 1.75
Shifting fungal reproductive mode by manipulation of mating type genes: obligatory heterothallism of Gibberella zeae. Mol Microbiol (2003) 1.72
Gene silencing and homology-dependent gene silencing in Arabidopsis: genetic modifiers and DNA methylation. Genetics (1998) 1.72
RNA silencing as a tool for exploring gene function in ascomycete fungi. Fungal Genet Biol (2005) 1.67
The Frequency and Degree of Cosuppression by Sense Chalcone Synthase Transgenes Are Dependent on Transgene Promoter Strength and Are Reduced by Premature Nonsense Codons in the Transgene Coding Sequence. Plant Cell (1997) 1.65
An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast. J Cell Biol (2001) 1.58
Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation. Proc Natl Acad Sci U S A (1993) 1.56
Meiotic silencing and the epigenetics of sex. Chromosome Res (2007) 1.52
A gene essential for de novo methylation and development in Ascobolus reveals a novel type of eukaryotic DNA methyltransferase structure. Cell (1997) 1.52
Aspergillus SteA (sterile12-like) is a homeodomain-C2/H2-Zn+2 finger transcription factor required for sexual reproduction. Mol Microbiol (2000) 1.51
Position-dependent and -independent mechanisms regulate cell-specific expression of the SpoC1 gene cluster of Aspergillus nidulans. Mol Cell Biol (1987) 1.47
RNAi-dependent and RNAi-independent mechanisms contribute to the silencing of RIPed sequences in Neurospora crassa. Nucleic Acids Res (2004) 1.38
Sex-induced silencing defends the genome of Cryptococcus neoformans via RNAi. Genes Dev (2010) 1.35
Internuclear gene silencing in Phytophthora infestans. Mol Cell (1999) 1.34
Homology-dependent gene silencing mechanisms in fungi. Annu Rev Microbiol (2001) 1.32
The gprA and gprB genes encode putative G protein-coupled receptors required for self-fertilization in Aspergillus nidulans. Mol Microbiol (2004) 1.29
Quelling: post-transcriptional gene silencing guided by small RNAs in Neurospora crassa. Curr Opin Microbiol (2007) 1.23
Aspergillus asexual reproduction and sexual reproduction are differentially affected by transcriptional and translational mechanisms regulating stunted gene expression. Mol Cell Biol (1997) 1.19
Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans. J Microbiol (2006) 1.13
Sexual sporulation. Prog Ind Microbiol (1994) 1.10
De novo methylation of repeated sequences in Coprinus cinereus. Genetics (1993) 1.08
Cosuppression comes to the animals. Cell (1997) 1.08
RNA silencing in Aspergillus nidulans is independent of RNA-dependent RNA polymerases. Genetics (2004) 1.07
Two pheromone precursor genes are transcriptionally expressed in the homothallic ascomycete Sordaria macrospora. Curr Genet (2000) 1.06
Mating type protein Mat1-2 from asexual Aspergillus fumigatus drives sexual reproduction in fertile Aspergillus nidulans. Eukaryot Cell (2008) 1.05
Microarray and real-time PCR analyses reveal mating type-dependent gene expression in a homothallic fungus. Mol Genet Genomics (2006) 1.05
Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling. Microbiology (2008) 1.04
Pheromones and pheromone receptors are required for proper sexual development in the homothallic ascomycete Sordaria macrospora. Genetics (2005) 1.03
Co-expression of the mating-type genes involved in internuclear recognition is lethal in Podospora anserina. Genetics (2000) 1.03
Homology-dependent silencing of the SC3 gene in Schizophyllum commune. Genetics (1997) 1.02
Properties of unpaired DNA required for efficient silencing in Neurospora crassa. Genetics (2004) 1.01
Internuclear recognition: A possible connection between euascomycetes and homobasidiomycetes. Fungal Genet Biol (1999) 1.00
A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans. PLoS One (2008) 0.96
A single transgene locus triggers both transcriptional and post-transcriptional silencing through double-stranded RNA production. Planta (2006) 0.95
Single mating type-specific genes and their 3' UTRs control mating and fertility in Cochliobolus heterostrophus. Mol Gen Genet (1998) 0.94
RNA silencing gene truncation in the filamentous fungus Aspergillus nidulans. Eukaryot Cell (2007) 0.92
Functional characterization of an alpha-factor-like Sordaria macrospora peptide pheromone and analysis of its interaction with its cognate receptor in Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.92
Unifying homology effects. Nat Genet (2002) 0.91
The RNA-dependent RNA polymerase, QDE-1, is a rate-limiting factor in post-transcriptional gene silencing in Neurospora crassa. Nucleic Acids Res (2004) 0.90
The tubB alpha-tubulin gene is essential for sexual development in Aspergillus nidulans. Genes Dev (1991) 0.89
Morphology and development in Aspergillus nidulans: a complex puzzle. Fungal Genet Biol (2009) 0.88
Complex mechanisms regulate developmental expression of the matA (HMG) mating type gene in homothallic Aspergillus nidulans. Genetics (2011) 0.80
Inducible RNA Interference of brlAbeta in Aspergillus nidulans. Eukaryot Cell (2008) 0.79
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science (2006) 27.96
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron (2011) 20.15
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain (2011) 9.90
Neurodegenerative diseases target large-scale human brain networks. Neuron (2009) 9.69
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55
Cognition and anatomy in three variants of primary progressive aphasia. Ann Neurol (2004) 7.07
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med (2007) 6.80
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Frontotemporal dementia: clinicopathological correlations. Ann Neurol (2006) 5.14
Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia. Ann Neurol (2008) 4.15
Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain (2010) 3.84
Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry (2010) 3.66
Distinctive neuropsychological patterns in frontotemporal dementia, semantic dementia, and Alzheimer disease. Cogn Behav Neurol (2003) 3.66
Challenging the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease. Arch Neurol (2003) 3.20
Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience. Radiology (2005) 3.14
Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis. AJNR Am J Neuroradiol (2005) 3.11
Predicting regional neurodegeneration from the healthy brain functional connectome. Neuron (2012) 3.07
Criteria for the diagnosis of corticobasal degeneration. Neurology (2013) 3.07
Frontal paralimbic network atrophy in very mild behavioral variant frontotemporal dementia. Arch Neurol (2008) 3.03
Rapidly progressive dementia. Ann Neurol (2008) 3.00
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies. J Neuropathol Exp Neurol (2008) 2.96
Neuroanatomical correlates of behavioural disorders in dementia. Brain (2005) 2.92
Unravelling Boléro: progressive aphasia, transmodal creativity and the right posterior neocortex. Brain (2007) 2.75
Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia. Brain (2007) 2.72
Clinical and pathological continuum of multisystem TDP-43 proteinopathies. Arch Neurol (2009) 2.68
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol (2008) 2.41
Early frontotemporal dementia targets neurons unique to apes and humans. Ann Neurol (2006) 2.38
Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol (2005) 2.36
FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration. Acta Neuropathol (2010) 2.30
Structural anatomy of empathy in neurodegenerative disease. Brain (2006) 2.28
Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch Neurol (2006) 2.27
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons. Acta Neuropathol (2013) 2.26
Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness. Proc Natl Acad Sci U S A (2002) 2.24
Connected speech production in three variants of primary progressive aphasia. Brain (2010) 2.19
The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. Arch Neurol (2010) 2.19
Diagnosis of human prion disease. Proc Natl Acad Sci U S A (2005) 2.13
Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease. Arch Neurol (2003) 2.12
White matter damage in frontotemporal dementia and Alzheimer's disease measured by diffusion MRI. Brain (2009) 2.08
Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08
TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol (2007) 2.02
Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging (2011) 2.01
Case records of the Massachusetts General Hospital. Case 9-2015. A 31-year-old man with personality changes and progressive neurologic decline. N Engl J Med (2015) 1.97
Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease. Brain (2013) 1.91
TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathol (2014) 1.90
Longitudinal MRI and cognitive change in healthy elderly. Neuropsychology (2007) 1.88
Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia. J Biol Chem (2011) 1.88
Relationships between β-amyloid and functional connectivity in different components of the default mode network in aging. Cereb Cortex (2011) 1.87
Clinicopathological correlations in corticobasal degeneration. Ann Neurol (2011) 1.86
Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden. Brain (2010) 1.86
Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol (2013) 1.84
Age effects on atrophy rates of entorhinal cortex and hippocampus. Neurobiol Aging (2005) 1.83
TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Mol Neurodegener (2013) 1.83
Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. Brain (2008) 1.82
Continuum of frontal lobe impairment in amyotrophic lateral sclerosis. Arch Neurol (2007) 1.81
Progressive nonfluent aphasia and its characteristic motor speech deficits. Alzheimer Dis Assoc Disord (2007) 1.78
TDP-43 frontotemporal lobar degeneration and autoimmune disease. J Neurol Neurosurg Psychiatry (2013) 1.74
White matter damage in primary progressive aphasias: a diffusion tensor tractography study. Brain (2011) 1.73
Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs (2010) 1.72
C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology (2013) 1.70
Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features. Neurology (2012) 1.69
Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol (2013) 1.68
Heightened emotional contagion in mild cognitive impairment and Alzheimer's disease is associated with temporal lobe degeneration. Proc Natl Acad Sci U S A (2013) 1.67
Perioperative cognitive decline in the aging population. Mayo Clin Proc (2011) 1.66
Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementias. Neurology (2013) 1.65
Ataxin-2 repeat-length variation and neurodegeneration. Hum Mol Genet (2011) 1.60
Gene expression study on peripheral blood identifies progranulin mutations. Ann Neurol (2008) 1.59
Rapidly progressive dementia. Neurol Clin (2007) 1.58
TDP-43 pathologic lesions and clinical phenotype in frontotemporal lobar degeneration with ubiquitin-positive inclusions. Arch Neurol (2007) 1.57
Automated MRI-based classification of primary progressive aphasia variants. Neuroimage (2009) 1.55
Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: reciprocal networks and neuronal evolution. Alzheimer Dis Assoc Disord (2007) 1.55
Double dissociation of social functioning in frontotemporal dementia. Neurology (2003) 1.54
Language networks in semantic dementia. Brain (2009) 1.50
Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia. Proc Natl Acad Sci U S A (2009) 1.49
Patterns of cognitive and emotional empathy in frontotemporal lobar degeneration. Cogn Behav Neurol (2005) 1.48
Prion proteins in subpopulations of white blood cells from patients with sporadic Creutzfeldt-Jakob disease. Lab Invest (2009) 1.48
Clinical features of frontotemporal dementia. Alzheimer Dis Assoc Disord (2005) 1.48
17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions. Arch Neurol (2004) 1.47
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet (2012) 1.46
A tensor based morphometry study of longitudinal gray matter contraction in FTD. Neuroimage (2007) 1.45
Cross-species translation of the Morris maze for Alzheimer's disease. J Clin Invest (2016) 1.43
Emotion comprehension in the temporal variant of frontotemporal dementia. Brain (2002) 1.40
Self-conscious emotion deficits in frontotemporal lobar degeneration. Brain (2006) 1.40
The diagnostic challenge of psychiatric symptoms in neurodegenerative disease: rates of and risk factors for prior psychiatric diagnosis in patients with early neurodegenerative disease. J Clin Psychiatry (2011) 1.40
Anatomical correlates of sentence comprehension and verbal working memory in neurodegenerative disease. J Neurosci (2007) 1.39
Detecting sarcasm from paralinguistic cues: anatomic and cognitive correlates in neurodegenerative disease. Neuroimage (2009) 1.38
The diagnostic utility of brain biopsy procedures in patients with rapidly deteriorating neurological conditions or dementia. J Neurosurg (2007) 1.37
White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy. Neurobiol Aging (2005) 1.36
Oculomotor function in frontotemporal lobar degeneration, related disorders and Alzheimer's disease. Brain (2008) 1.36
The neural basis of surface dyslexia in semantic dementia. Brain (2008) 1.36
Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion. J Neurol Neurosurg Psychiatry (2012) 1.34
Gender modulates the APOE ε4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels. J Neurosci (2012) 1.34
Patterns of cerebral atrophy in primary progressive aphasia. Am J Geriatr Psychiatry (2002) 1.34
Multiple cognitive deficits in amnestic mild cognitive impairment. Dement Geriatr Cogn Disord (2006) 1.33
Cinguloparietal atrophy distinguishes Alzheimer disease from semantic dementia. Arch Neurol (2003) 1.33
Syntactic processing depends on dorsal language tracts. Neuron (2011) 1.31
Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype. Neurobiol Aging (2012) 1.30
Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter. Ann Neurol (2002) 1.30
Neural basis of interpersonal traits in neurodegenerative diseases. Neuropsychologia (2009) 1.29
Accuracy of the clinical evaluation for frontotemporal dementia. Arch Neurol (2007) 1.29