Toshiro Aigaki

Author PubWeight™ 79.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway. EMBO J 2002 3.16
2 Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia. PLoS Biol 2007 3.03
3 GETDB, a database compiling expression patterns and molecular locations of a collection of Gal4 enhancer traps. Genesis 2002 2.14
4 Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae. Proc Natl Acad Sci U S A 2002 1.99
5 Dally regulates Dpp morphogen gradient formation in the Drosophila wing. Development 2003 1.94
6 Alternative trans-splicing: a novel mode of pre-mRNA processing. Biol Cell 2006 1.92
7 Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation. Curr Biol 2004 1.87
8 An unconventional myosin in Drosophila reverses the default handedness in visceral organs. Nature 2006 1.60
9 IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis. Curr Biol 2006 1.57
10 Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe. Nat Neurosci 2007 1.53
11 MachiBase: a Drosophila melanogaster 5'-end mRNA transcription database. Nucleic Acids Res 2008 1.33
12 Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola. Genes Dev 2003 1.33
13 The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila. Development 2007 1.29
14 The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila. EMBO Rep 2005 1.20
15 Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila. Nat Neurosci 2003 1.20
16 Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis. Development 2008 1.10
17 An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila. EMBO J 2006 1.10
18 Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis. Genetics 2011 1.06
19 A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. Genetics 2005 1.05
20 The calcineurin regulator sra plays an essential role in female meiosis in Drosophila. Curr Biol 2006 1.05
21 Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog. Dev Biol 2005 1.03
22 POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila. FEBS Lett 2006 1.00
23 Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice. Arch Biochem Biophys 2010 0.96
24 Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis. Proc Natl Acad Sci U S A 2012 0.95
25 Drosophila lola encodes a family of BTB-transcription regulators with highly variable C-terminal domains containing zinc finger motifs. Gene 2003 0.95
26 Calcineurin and its regulator sra/DSCR1 are essential for sleep in Drosophila. J Neurosci 2011 0.94
27 Calcineurin and its regulation by Sra/RCAN is required for completion of meiosis in Drosophila. Dev Biol 2010 0.93
28 Pan-neuronal knockdown of calcineurin reduces sleep in the fruit fly, Drosophila melanogaster. J Neurosci 2011 0.92
29 Mitochondrial protein Preli-like is required for development of dendritic arbors and prevents their regression in the Drosophila sensory nervous system. Development 2009 0.92
30 Formin3 is required for assembly of the F-actin structure that mediates tracheal fusion in Drosophila. Dev Biol 2004 0.90
31 Defective transfer of seminal-fluid materials during matings of semi-fertile fruitless mutants in Drosophila. J Comp Physiol A Neuroethol Sens Neural Behav Physiol 2006 0.90
32 Differential control of cell affinity required for progression and refinement of cell boundary during Drosophila leg segmentation. Dev Biol 2007 0.90
33 Misexpression screen for genes altering the olfactory map in Drosophila. Genesis 2006 0.89
34 A gain-of-function screen identifies wdb and lkb1 as lifespan-extending genes in Drosophila. Biochem Biophys Res Commun 2011 0.88
35 Insulin-degrading enzyme antagonizes insulin-dependent tissue growth and Abeta-induced neurotoxicity in Drosophila. FEBS Lett 2010 0.86
36 Behavioral analyses of mutants for two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila melanogaster. Genes Genet Syst 2008 0.86
37 Functional evolution of duplicated odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. PLoS One 2012 0.86
38 Loss of Trx-2 enhances oxidative stress-dependent phenotypes in Drosophila. FEBS Lett 2010 0.86
39 Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity. Biochim Biophys Acta 2005 0.86
40 Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila. J Biol Chem 2007 0.85
41 The slender lobes gene, identified by retarded mushroom body development, is required for proper nucleolar organization in Drosophila. Dev Biol 2005 0.85
42 Evolution of expression patterns of two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. Gene 2010 0.84
43 Protein kinase A inhibits a consolidated form of memory in Drosophila. Proc Natl Acad Sci U S A 2008 0.84
44 Forked end: a novel transmembrane protein involved in neuromuscular specificity in drosophila identified by gain-of-function screening. J Neurobiol 2002 0.84
45 The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. Development 2011 0.84
46 The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state. PLoS Genet 2013 0.83
47 Efficient measurement of H2O2 resistance in Drosophila using an activity monitor. Biogerontology 2003 0.83
48 In vivo hyaluronan synthesis upon expression of the mammalian hyaluronan synthase gene in Drosophila. J Biol Chem 2004 0.82
49 Interaction of cytoskeleton genes with NSF2-induced neuromuscular junction overgrowth. Genesis 2006 0.82
50 Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity. Proc Natl Acad Sci U S A 2009 0.82
51 A fluorogenic peptide probe developed by in vitro selection using tRNA carrying a fluorogenic amino acid. Chem Commun (Camb) 2013 0.81
52 Effects of ascorbic acid deficiency on protein and lipid oxidation in livers from SMP30/GNL knockout mice. J Nutr Sci Vitaminol (Tokyo) 2013 0.81
53 Overexpression of grappa encoding a histone methyltransferase enhances stress resistance in Drosophila. Hereditas 2009 0.81
54 A novel classification system for evolutionary aging theories. Front Genet 2013 0.81
55 Effect of ascorbic acid deficiency on catecholamine synthesis in adrenal glands of SMP30/GNL knockout mice. Eur J Nutr 2013 0.80
56 A mev-1-like dominant-negative SdhC increases oxidative stress and reduces lifespan in Drosophila. Biochem Biophys Res Commun 2007 0.80
57 Comparative sequence analysis of a gene-dense region among closely related species of Drosophila melanogaster. Genes Genet Syst 2004 0.80
58 Involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in disc specification. Proc Natl Acad Sci U S A 2005 0.80
59 An epidermal growth factor derivative with binding affinity for hydroxyapatite and titanium surfaces. Biomaterials 2013 0.80
60 Impaired fatty acid oxidation in a Drosophila model of mitochondrial trifunctional protein (MTP) deficiency. Biochem Biophys Res Commun 2012 0.80
61 Bioluminescence imaging to track real-time armadillo promoter activity in live Drosophila embryos. Anal Bioanal Chem 2014 0.79
62 Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome. PLoS One 2010 0.79
63 Identification of trf2 mutants of Drosophila with defects in anterior spiracle eversion. Arch Insect Biochem Physiol 2007 0.79
64 Positively charged cholesterol-recombinant human gelatins foster the cellular uptake of proteins and murine immune reactions. Int J Nanomedicine 2012 0.78
65 Expression level of sarah, a homolog of DSCR1, is critical for ovulation and female courtship behavior in Drosophila melanogaster. Genetics 2004 0.78
66 Conserved cis-regulatory elements of two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila. Genes Genet Syst 2012 0.78
67 D-JNK signaling in visceral muscle cells controls the laterality of the Drosophila gut. Dev Biol 2007 0.77
68 POSH promotes cell survival in Drosophila and in human RASF cells. FEBS Lett 2010 0.77
69 Senemorphism: a novel perspective on aging patterns and its implication for diet-related biology. Biogerontology 2012 0.77
70 In vitro selection of a peptide aptamer that changes fluorescence in response to verotoxin. Biotechnol Lett 2014 0.77
71 Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase. J Biochem 2005 0.77
72 Cationic cholesterol-modified gelatin as an in vitro siRNA delivery vehicle. Mol Biosyst 2013 0.77
73 Age-related changes of dopamine, noradrenaline and adrenaline in adrenal glands of mice. Geriatr Gerontol Int 2012 0.76
74 Impaired energy metabolism in a Drosophila model of mitochondrial aconitase deficiency. Biochem Biophys Res Commun 2013 0.76
75 A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster. BMC Genet 2014 0.76
76 The Drosophila calcineurin regulator, Sarah, is involved in male courtship. Neuroreport 2010 0.76
77 Structural basis of the γ-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase. PLoS One 2013 0.76
78 Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster. BMC Complement Altern Med 2012 0.75
79 Polypeptide aptamer selection using a stabilized ribosome display. J Biosci Bioeng 2011 0.75
80 Identification of a novel role for Drosophila MESR4 in lipid metabolism. Genes Cells 2015 0.75
81 Establishment and characterization of hepatocytes from an Immortomouse/SMP30/GNL knockout mouse hybrid lacking vitamin C to study vitamin C transport. J Biochem 2011 0.75