PubRank

Stephen T Warren

Author PubWeight™ 123.30‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The mGluR theory of fragile X mental retardation. Trends Neurosci 2004 8.88
2 Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci U S A 2002 6.45
3 Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function. Neuron 2008 6.26
4 Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 2004 4.69
5 A decade of molecular studies of fragile X syndrome. Annu Rev Neurosci 2002 3.54
6 An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities. Genet Med 2011 3.51
7 Pur alpha binds to rCGG repeats and modulates repeat-mediated neurodegeneration in a Drosophila model of fragile X tremor/ataxia syndrome. Neuron 2007 3.17
8 The pathophysiology of fragile x syndrome. Annu Rev Genomics Hum Genet 2007 2.85
9 RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila. Neuron 2003 2.81
10 Deletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia. Am J Hum Genet 2010 2.70
11 Phosphorylation influences the translation state of FMRP-associated polyribosomes. Hum Mol Genet 2003 2.66
12 RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 2004 2.63
13 Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Hum Mol Genet 2007 2.55
14 Age-associated DNA methylation in pediatric populations. Genome Res 2012 2.53
15 Relative burden of large CNVs on a range of neurodevelopmental phenotypes. PLoS Genet 2011 2.46
16 Molecular mechanisms of fragile X syndrome: a twenty-year perspective. Annu Rev Pathol 2011 2.39
17 Microdeletions of 3q29 confer high risk for schizophrenia. Am J Hum Genet 2010 2.38
18 The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development. Proc Natl Acad Sci U S A 2004 2.34
19 Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. Mol Cell 2011 2.27
20 Replication stress induces tumor-like microdeletions in FHIT/FRA3B. Proc Natl Acad Sci U S A 2007 2.27
21 Incidence of fragile X syndrome by newborn screening for methylated FMR1 DNA. Am J Hum Genet 2009 2.12
22 Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc Natl Acad Sci U S A 2007 2.10
23 Replication stress induces genome-wide copy number changes in human cells that resemble polymorphic and pathogenic variants. Am J Hum Genet 2009 2.07
24 Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat Chem Biol 2008 2.04
25 FMRP phosphorylation reveals an immediate-early signaling pathway triggered by group I mGluR and mediated by PP2A. J Neurosci 2007 2.02
26 Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome. J Neurosci 2010 1.89
27 S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade. J Biol Chem 2008 1.87
28 Local RNA translation at the synapse and in disease. J Neurosci 2011 1.83
29 Fragile X syndrome. Eur J Hum Genet 2008 1.81
30 Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. Sci Transl Med 2012 1.72
31 Transcription, translation and fragile X syndrome. Curr Opin Genet Dev 2006 1.72
32 New insights into fragile X syndrome: from molecules to neurobehaviors. Trends Biochem Sci 2003 1.68
33 Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A 2010 1.64
34 Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome. Am J Hum Genet 2002 1.59
35 A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet 2012 1.52
36 Polyglutamine domain modulates the TBP-TFIIB interaction: implications for its normal function and neurodegeneration. Nat Neurosci 2007 1.46
37 Microarray-based mutation detection in the dystrophin gene. Hum Mutat 2008 1.39
38 Physiological identification of human transcripts translationally regulated by a specific microRNA. Hum Mol Genet 2005 1.39
39 Hemizygous mutations in SNAP29 unmask autosomal recessive conditions and contribute to atypical findings in patients with 22q11.2DS. J Med Genet 2012 1.33
40 Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol 2013 1.27
41 The unstable repeats--three evolving faces of neurological disease. Neuron 2013 1.26
42 New perspectives on the biology of fragile X syndrome. Curr Opin Genet Dev 2012 1.23
43 A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels. Blood 2007 1.22
44 Mosaic FMR1 deletion causes fragile X syndrome and can lead to molecular misdiagnosis: a case report and review of the literature. Am J Med Genet A 2008 1.21
45 Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum Mol Genet 2012 1.21
46 Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males. Am J Med Genet A 2010 1.16
47 Neurogenetics: advancing the "next-generation" of brain research. Neuron 2010 1.16
48 Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell 2005 1.14
49 The fragile X mental retardation protein, FMRP, recognizes G-quartets. Ment Retard Dev Disabil Res Rev 2004 1.14
50 Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice. BMC Genomics 2014 1.03
51 Fragile X syndrome: an update and review for the primary pediatrician. Clin Pediatr (Phila) 2005 1.01
52 Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation. PLoS Genet 2007 0.99
53 Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus. BMC Med Genet 2013 0.97
54 Gene expression profiles in a transgenic animal model of fragile X syndrome. Neurobiol Dis 2002 0.96
55 Array-based FMR1 sequencing and deletion analysis in patients with a fragile X syndrome-like phenotype. PLoS One 2010 0.93
56 Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity. J Neurochem 2004 0.89
57 Neuroscience: fragile dopamine. Nature 2008 0.87
58 Empirical evaluation of oligonucleotide probe selection for DNA microarrays. PLoS One 2010 0.84
59 Molecular diagnosis of Beckwith-Wiedemann syndrome using quantitative methylation-sensitive polymerase chain reaction. Genet Med 2006 0.82
60 Toward pluripotency by reprogramming: mechanisms and application. Protein Cell 2013 0.81
61 Development and characterization of antibodies that immunoprecipitate the FMR1 protein. Methods Mol Biol 2003 0.79
62 Genomic tics in tourette syndrome. Biol Psychiatry 2012 0.75
63 The human genome: a diamond in the rough. Curr Opin Genet Dev 2012 0.75