Published in Proc Natl Acad Sci U S A on January 28, 2013
Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development. Front Oncol (2013) 0.98
Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks. Nat Med (2014) 0.90
Pathway analysis for drug repositioning based on public database mining. J Chem Inf Model (2014) 0.80
Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases. Gastroenterology (2016) 0.76
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science (2006) 25.99
Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci Transl Med (2011) 5.77
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci Transl Med (2011) 5.30
Algorithm discovery by protein folding game players. Proc Natl Acad Sci U S A (2011) 3.74
Exploiting drug-disease relationships for computational drug repositioning. Brief Bioinform (2011) 2.52
Straight talk with...Mac Cowell and Jason Bobe. Interview by Prashant Nair. Nat Med (2009) 1.69
Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β. J Alzheimers Dis (2012) 0.98
An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features. EMBO Rep (2006) 1.34
Brown and Goldstein: the cholesterol chronicles. Proc Natl Acad Sci U S A (2013) 1.14
Profile of Shinya Yamanaka. Proc Natl Acad Sci U S A (2012) 0.84
Conservation genomics. Proc Natl Acad Sci U S A (2014) 0.83
Analysis of protein transport to lysosomes. Curr Protoc Cell Biol (2005) 0.82
Woese and Fox: Life, rearranged. Proc Natl Acad Sci U S A (2012) 0.82
As IVF becomes more common, some concerns remain. Nat Med (2008) 0.77
Transcatheter closure of acquired Gerbode defect following mitral valve replacement using the Amplatzer duct occluder. J Invasive Cardiol (2006) 0.76
Connectome. Proc Natl Acad Sci U S A (2013) 0.75
QnAs with Thomas Jessell. Proc Natl Acad Sci U S A (2014) 0.75
Profile of Charles L. Sawyers. Proc Natl Acad Sci U S A (2011) 0.75
QnAs with Stephen Quake. Proc Natl Acad Sci U S A (2016) 0.75
QnAs with Joseph LeDoux. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Hopi Hoekstra. Proc Natl Acad Sci U S A (2015) 0.75
Profile of David J. Mangelsdorf. Proc Natl Acad Sci U S A (2010) 0.75
QnAs with Ben Barres. Proc Natl Acad Sci U S A (2015) 0.75
Profile of Gary Ruvkun. Proc Natl Acad Sci U S A (2011) 0.75
Profile of Charles M. Rice. Proc Natl Acad Sci U S A (2011) 0.75
QnAs with Patricia Kuhl. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Rino Rappuoli. Proc Natl Acad Sci U S A (2017) 0.75
Profile of Charles Stanish. Proc Natl Acad Sci U S A (2012) 0.75
Brain-machine interface. Proc Natl Acad Sci U S A (2013) 0.75
QnAs with Tom Insel. Proc Natl Acad Sci U S A (2014) 0.75
Profile of Jean-Laurent Casanova. Proc Natl Acad Sci U S A (2015) 0.75
Sequencing ancient DNA. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Karl Deisseroth. Proc Natl Acad Sci U S A (2016) 0.75
Profile of B. Rosemary Grant. Proc Natl Acad Sci U S A (2011) 0.75
QnAs with Elizabeth Spelke. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Jennifer Doudna. Proc Natl Acad Sci U S A (2016) 0.75
QnAs with Huda Y. Zoghbi. Proc Natl Acad Sci U S A (2016) 0.75
Profile of Daniel G. Nocera. Proc Natl Acad Sci U S A (2012) 0.75
Profile of Michael A. Marletta. Proc Natl Acad Sci U S A (2010) 0.75
Profile of George M. Church. Proc Natl Acad Sci U S A (2012) 0.75
Nonpathogenic prions. Proc Natl Acad Sci U S A (2013) 0.75
Profile of Peter H. Schiller. Proc Natl Acad Sci U S A (2011) 0.75
QnAs with Gerald M. Rubin. Proc Natl Acad Sci U S A (2016) 0.75
QnAs with Victor Dzau. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Madhav Gadgil. Proc Natl Acad Sci U S A (2015) 0.75
QnAs with Tony Hunter and James Allison. Proc Natl Acad Sci U S A (2017) 0.75
QnAs with Venki Ramakrishnan. Proc Natl Acad Sci U S A (2015) 0.75
QnAs with Fred Gage. Proc Natl Acad Sci U S A (2014) 0.75
QnAs with Luciana Borio. Proc Natl Acad Sci U S A (2017) 0.75
QnAs with James Allison. Proc Natl Acad Sci U S A (2016) 0.75
National Cancer Institute helps businesses cross 'the valley of death'. Nat Med (2008) 0.75
Studies comparing treatment options receive a boost. Nat Med (2009) 0.75
Avian acrobatics. Proc Natl Acad Sci U S A (2013) 0.75
QnAs with Marcia McNutt. Proc Natl Acad Sci U S A (2017) 0.75
QnAs with Alta Charo and George Church. Proc Natl Acad Sci U S A (2017) 0.75
Tracking Burmese pythons. Proc Natl Acad Sci U S A (2013) 0.75
QnAs with Karel Svoboda. Proc Natl Acad Sci U S A (2017) 0.75
QnAs with Rodolphe Barrangou. Proc Natl Acad Sci U S A (2017) 0.75
Massachusetts pours money into local life sciences research. Nat Med (2008) 0.75