Published in BMC Med Genomics on January 23, 2013
Age-adjusted nonparametric detection of differential DNA methylation with case-control designs. BMC Bioinformatics (2013) 0.92
A new statistical approach to combining p-values using gamma distribution and its application to genome-wide association study. BMC Bioinformatics (2014) 0.87
Simultaneous statistical inference for epigenetic data. PLoS One (2015) 0.83
Detecting differentially methylated loci for multiple treatments based on high-throughput methylation data. BMC Bioinformatics (2014) 0.83
Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort. Behav Genet (2014) 0.76
The current trend of genomics research for human diseases. BMC Med Genomics (2013) 0.75
The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05
The history of cancer epigenetics. Nat Rev Cancer (2004) 14.38
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol (2008) 11.28
Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer (2006) 11.22
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Increased methylation variation in epigenetic domains across cancer types. Nat Genet (2011) 8.92
Estimation of significance thresholds for genomewide association scans. Genet Epidemiol (2008) 8.88
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet (2009) 7.07
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature (1999) 6.42
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. Genome Res (2010) 6.03
A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet Epidemiol (2008) 5.07
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res (2008) 4.84
DNA methylation and cancer. Adv Genet (2010) 3.50
On multiple-testing correction in genome-wide association studies. Genet Epidemiol (2008) 3.19
A statistical framework for Illumina DNA methylation arrays. Bioinformatics (2010) 1.92
Cytosine methylation and CpG, TpG (CpA) and TpA frequencies. Gene (2004) 1.78
Is the weighted z-test the best method for combining probabilities from independent tests? J Evol Biol (2011) 1.56
A robust method for testing association in genome-wide association studies. Hum Hered (2011) 1.08
Method to detect differentially methylated loci with case-control designs using Illumina arrays. Genet Epidemiol (2011) 1.07
A new statistical approach to detecting differentially methylated loci for case control Illumina array methylation data. Bioinformatics (2012) 1.06
A new approach to account for the correlations among single nucleotide polymorphisms in genome: wide association studies. Hum Hered (2011) 1.04
A new association test based on Chi-square partition for case-control GWA studies. Genet Epidemiol (2011) 1.03
Comments on 'Choosing an optimal method to combine p-values' by Sungho Won, Nathan Morris, Qing Lu and Robert C. Elston, Statistics in Medicine 2009; 28:1537-1553. Stat Med (2011) 0.93
Age-adjusted nonparametric detection of differential DNA methylation with case-control designs. BMC Bioinformatics (2013) 0.92
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
Joint analysis of two microarray gene-expression data sets to select lung adenocarcinoma marker genes. BMC Bioinformatics (2004) 2.73
Statistical distribution of the difference of two proportions. Stat Med (2007) 2.04
An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. J Biol Chem (2002) 2.00
GeneVenn - A web application for comparing gene lists using Venn diagrams. Bioinformation (2007) 2.00
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). J Biol Chem (2002) 1.99
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet (2003) 1.91
Synovial fibroblasts promote osteoclast formation by RANKL in a novel model of spontaneous erosive arthritis. Arthritis Rheum (2005) 1.79
Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance. Diabetes (2002) 1.78
Simulating association studies: a data-based resampling method for candidate regions or whole genome scans. Bioinformatics (2007) 1.77
Nonparametric Bayesian variable selection with applications to multiple quantitative trait loci mapping with epistasis and gene-environment interaction. Genetics (2010) 1.48
A comparative study of different machine learning methods on microarray gene expression data. BMC Genomics (2008) 1.46
Recent advances in clustering methods for protein interaction networks. BMC Genomics (2010) 1.40
Large-scale gene expression differences across brain regions and inbred strains correlate with a behavioral phenotype. Genetics (2006) 1.37
Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling. Mol Endocrinol (2003) 1.33
Extensive pyrosequencing reveals frequent intra-genomic variations of internal transcribed spacer regions of nuclear ribosomal DNA. PLoS One (2012) 1.31
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry (2004) 1.30
A review of independent component analysis application to microarray gene expression data. Biotechniques (2008) 1.24
Candidate's thesis: enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing loss. Laryngoscope (2002) 1.24
The Tobacco mosaic virus 126-kDa protein associated with virus replication and movement suppresses RNA silencing. Mol Plant Microbe Interact (2004) 1.22
Identification of plasma lipid biomarkers for prostate cancer by lipidomics and bioinformatics. PLoS One (2012) 1.21
N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease. Curr Alzheimer Res (2012) 1.20
NAC for noise: from the bench top to the clinic. Hear Res (2006) 1.20
Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1. J Biol Chem (2010) 1.20
Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC). J Proteome Res (2006) 1.20
Comparison of probabilistic Boolean network and dynamic Bayesian network approaches for inferring gene regulatory networks. BMC Bioinformatics (2007) 1.15
Differential contribution of insulin receptor substrates 1 versus 2 to insulin signaling and glucose uptake in l6 myotubes. J Biol Chem (2005) 1.14
Prevention of impulse noise-induced hearing loss with antioxidants. Acta Otolaryngol (2005) 1.14
Toxicogenomic analysis provides new insights into molecular mechanisms of the sublethal toxicity of 2,4,6-trinitrotoluene in Eisenia fetida. Environ Sci Technol (2007) 1.14
Feature selection and classification of MAQC-II breast cancer and multiple myeloma microarray gene expression data. PLoS One (2009) 1.11
R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression. FEBS Lett (2008) 1.11
Functional identification of three receptor activator of NF-kappa B cytoplasmic motifs mediating osteoclast differentiation and function. J Biol Chem (2004) 1.11
Speckle reducing bilateral filter for cattle follicle segmentation. BMC Genomics (2010) 1.10
Gene selection and classification for cancer microarray data based on machine learning and similarity measures. BMC Genomics (2011) 1.10
Cloning, analysis and functional annotation of expressed sequence tags from the Earthworm Eisenia fetida. BMC Bioinformatics (2007) 1.09
Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer. BMC Genomics (2014) 1.08
Noise protection with N-acetyl-l-cysteine (NAC) using a variety of noise exposures, NAC doses, and routes of administration. Acta Otolaryngol (2007) 1.07
A new statistical approach to detecting differentially methylated loci for case control Illumina array methylation data. Bioinformatics (2012) 1.06
A novel receptor activator of NF-kappaB (RANK) cytoplasmic motif plays an essential role in osteoclastogenesis by committing macrophages to the osteoclast lineage. J Biol Chem (2005) 1.06
Clathrin light chains regulate clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis. Plant Cell (2013) 1.05
Identification of genes and pathways involved in kidney renal clear cell carcinoma. BMC Bioinformatics (2014) 1.05
Perioperative assessment of platelet function by Thromboelastograph Platelet Mapping in cardiovascular patients undergoing non-cardiac surgery. J Thromb Thrombolysis (2013) 1.04
SVM Classifier - a comprehensive java interface for support vector machine classification of microarray data. BMC Bioinformatics (2006) 1.04
Transcriptomic analysis of RDX and TNT interactive sublethal effects in the earthworm Eisenia fetida. BMC Genomics (2008) 1.04
TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-kappaB. J Biol Chem (2011) 1.03
High preoperative plasma fibrinogen levels are associated with distant metastases and impaired prognosis after curative resection in patients with colorectal cancer. J Surg Oncol (2010) 1.02
Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus. BMC Med Genomics (2013) 1.02
The E and G subunits of the yeast V-ATPase interact tightly and are both present at more than one copy per V1 complex. J Biol Chem (2006) 1.02
MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity. BMC Genomics (2014) 1.02
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases. Biochim Biophys Acta (2008) 1.01
High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles. BMC Biotechnol (2007) 1.00
3D protein structure prediction with genetic tabu search algorithm. BMC Syst Biol (2010) 1.00
Glucocorticoid regulation of genes in the amiloride-sensitive sodium transport pathway by semicircular canal duct epithelium of neonatal rat. Physiol Genomics (2005) 1.00
Magnetic nanoparticles: inner ear targeted molecule delivery and middle ear implant. Audiol Neurootol (2006) 1.00
Receptor activator of NF-{kappa}B (RANK) cytoplasmic IVVY535-538 motif plays an essential role in tumor necrosis factor-{alpha} (TNF)-mediated osteoclastogenesis. J Biol Chem (2010) 1.00
A novel gene network inference algorithm using predictive minimum description length approach. BMC Syst Biol (2010) 1.00
Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochem Soc Trans (2008) 0.99
Comparison of feature selection and classification for MALDI-MS data. BMC Genomics (2009) 0.99
Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Exp Gerontol (2004) 0.98
A transgenic mouse model to study glucose transporter 4myc regulation in skeletal muscle. Endocrinology (2008) 0.98
Metal exposure and Alzheimer's pathogenesis. J Struct Biol (2006) 0.98
Investigation of transmembrane proteins using a computational approach. BMC Genomics (2008) 0.98
Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes. J Clin Endocrinol Metab (2015) 0.98
Distribution of PLGA nanoparticles in chinchilla cochleae. Otolaryngol Head Neck Surg (2007) 0.96
Batch Blast Extractor: an automated blastx parser application. BMC Genomics (2008) 0.96
From raw materials to validated system: the construction of a genomic library and microarray to interpret systemic perturbations in Northern bobwhite. Physiol Genomics (2010) 0.96
Independent component analysis-based classification of Alzheimer's disease MRI data. J Alzheimers Dis (2011) 0.96
Myocyte enhancer factor 2 and microphthalmia-associated transcription factor cooperate with NFATc1 to transactivate the V-ATPase d2 promoter during RANKL-induced osteoclastogenesis. J Biol Chem (2009) 0.96
Computational identification of novel chitinase-like proteins in the Drosophila melanogaster genome. Bioinformatics (2004) 0.95
Statistical methods on detecting differentially expressed genes for RNA-seq data. BMC Syst Biol (2011) 0.95
A Distribution-Free Convolution Model for background correction of oligonucleotide microarray data. BMC Genomics (2009) 0.95
Mass segmentation using a combined method for cancer detection. BMC Syst Biol (2011) 0.95
Neurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus). Toxicol Sci (2009) 0.95
The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. J Neural Transm (Vienna) (2011) 0.94
Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis. J Biol Chem (2012) 0.94
Comments on 'Choosing an optimal method to combine p-values' by Sungho Won, Nathan Morris, Qing Lu and Robert C. Elston, Statistics in Medicine 2009; 28:1537-1553. Stat Med (2011) 0.93
Analyzing adjuvant radiotherapy suggests a non monotonic radio-sensitivity over tumor volumes. BMC Genomics (2008) 0.93
Age-adjusted nonparametric detection of differential DNA methylation with case-control designs. BMC Bioinformatics (2013) 0.92
Independent component analysis of Alzheimer's DNA microarray gene expression data. Mol Neurodegener (2009) 0.92
Influence of microstructure on superconductivity in KxFe₂-ySe₂ and evidence for a new parent phase K₂Fe₇Se₈. Nat Commun (2013) 0.92
Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element. Int J Mol Sci (2009) 0.92
Design and analysis of multiple diseases genome-wide association studies without controls. Gene (2012) 0.92
Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. Eur J Cancer (2010) 0.91
Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease. PLoS One (2013) 0.91
Exploring the pathogenetic association between schizophrenia and type 2 diabetes mellitus diseases based on pathway analysis. BMC Med Genomics (2013) 0.91
Novel implementation of conditional co-regulation by graph theory to derive co-expressed genes from microarray data. BMC Bioinformatics (2008) 0.91
Supervised learning-based tagSNP selection for genome-wide disease classifications. BMC Genomics (2008) 0.90
Development of a novel DNA sequencing method not only for hepatitis B virus genotyping but also for drug resistant mutation detection. BMC Med Genomics (2013) 0.89
An MRI study of symptomatic adhesive capsulitis. PLoS One (2012) 0.89
Promoting synergistic research and education in genomics and bioinformatics. BMC Genomics (2008) 0.89
HDAM: a resource of human disease associated mutations from next generation sequencing studies. BMC Med Genomics (2013) 0.89
RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine. Curr Alzheimer Res (2006) 0.88