PubRank

Georges Mer

Author PubWeight™ 51.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006 8.12
2 The BRCT domain is a phospho-protein binding domain. Science 2003 7.42
3 Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol 2013 3.18
4 Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. Nat Genet 2011 3.16
5 RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J 2012 2.34
6 Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor. Nat Struct Mol Biol 2007 2.22
7 Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure 2004 1.82
8 Molecular basis for the association of human E4B U box ubiquitin ligase with E2-conjugating enzymes UbcH5c and Ubc4. Structure 2010 1.58
9 MCPH1 functions in an H2AX-dependent but MDC1-independent pathway in response to DNA damage. J Biol Chem 2007 1.55
10 Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation. EMBO J 2011 1.52
11 The tandem BRCT domain of 53BP1 is not required for its repair function. J Biol Chem 2006 1.45
12 Structural basis for the recognition of methylated histone H3K36 by the Eaf3 subunit of histone deacetylase complex Rpd3S. Structure 2008 1.29
13 Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature 2012 1.21
14 PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat Struct Mol Biol 2012 1.09
15 Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23. J Biol Chem 2009 1.01
16 Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites. J Mol Biol 2008 1.01
17 Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Mol Pharmacol 2006 0.99
18 Structure and histone binding properties of the Vps75-Rtt109 chaperone-lysine acetyltransferase complex. J Biol Chem 2011 0.95
19 Histone chaperone Rtt106 promotes nucleosome formation using (H3-H4)2 tetramers. J Biol Chem 2012 0.93
20 Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. Proc Natl Acad Sci U S A 2012 0.93
21 Heme-based sensing by the mammalian circadian protein CLOCK. Inorg Chem 2010 0.93
22 Interaction of asymmetric ABCC9-encoded nucleotide binding domains determines KATP channel SUR2A catalytic activity. J Proteome Res 2008 0.89
23 DNMT1 mutation hot spot causes varied phenotypes of HSAN1 with dementia and hearing loss. Neurology 2013 0.88
24 Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation. Biochemistry 2009 0.88
25 Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase ι. Biochemistry 2010 0.87
26 The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin function. J Biol Chem 2012 0.86
27 Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations. Biochemistry 2008 0.84
28 Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex. J Biol Chem 2011 0.81
29 Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons. Neurology 2014 0.76
30 (1)H, (15)N and (13)C resonance assignments for the three LOTUS RNA binding domains of Tudor domain-containing protein TDRD7. Biomol NMR Assign 2012 0.75