Published in J Neurosci on February 13, 2013
Carotid chemoreceptor ablation improves survival in heart failure: rescuing autonomic control of cardiorespiratory function. J Am Coll Cardiol (2013) 2.31
Vesicular glutamate transporter 2 is required for the respiratory and parasympathetic activation produced by optogenetic stimulation of catecholaminergic neurons in the rostral ventrolateral medulla of mice in vivo. Eur J Neurosci (2013) 1.48
C1 neurons: the body's EMTs. Am J Physiol Regul Integr Comp Physiol (2013) 1.19
Regulation of breathing and autonomic outflows by chemoreceptors. Compr Physiol (2014) 1.09
Carotid body chemoreceptors, sympathetic neural activation, and cardiometabolic disease. Biol Res (2016) 0.99
Contribution of peripheral and central chemoreceptors to sympatho-excitation in heart failure. J Physiol (2016) 0.93
When norepinephrine becomes a driver of breathing irregularities: how intermittent hypoxia fundamentally alters the modulatory response of the respiratory network. J Neurosci (2014) 0.92
Optogenetic stimulation of adrenergic C1 neurons causes sleep state-dependent cardiorespiratory stimulation and arousal with sighs in rats. Am J Respir Crit Care Med (2014) 0.89
P2Y1 receptors expressed by C1 neurons determine peripheral chemoreceptor modulation of breathing, sympathetic activity, and blood pressure. Hypertension (2013) 0.88
State-dependent control of breathing by the retrotrapezoid nucleus. J Physiol (2015) 0.87
Monosynaptic glutamatergic activation of locus coeruleus and other lower brainstem noradrenergic neurons by the C1 cells in mice. J Neurosci (2013) 0.85
Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis. J Neurosci (2015) 0.85
Chemoreception and asphyxia-induced arousal. Respir Physiol Neurobiol (2013) 0.84
Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods? Front Neurosci (2013) 0.82
The orexinergic neurons receive synaptic input from C1 cells in rats. J Comp Neurol (2014) 0.82
Optogenetic excitation of preBötzinger complex neurons potently drives inspiratory activity in vivo. J Physiol (2015) 0.81
Transient Suppression of Dbx1 PreBötzinger Interneurons Disrupts Breathing in Adult Mice. PLoS One (2016) 0.77
Afferent and efferent connections of C1 cells with spinal cord or hypothalamic projections in mice. Brain Struct Funct (2015) 0.77
Relevance of the Carotid Body Chemoreflex in the Progression of Heart Failure. Biomed Res Int (2015) 0.76
The retrotrapezoid nucleus stimulates breathing by releasing glutamate in adult conscious mice. Eur J Neurosci (2015) 0.76
AMP-activated Protein Kinase Deficiency Blocks the Hypoxic Ventilatory Response and Thus Precipitates Hypoventilation and Apnea. Am J Respir Crit Care Med (2016) 0.75
Selective optogenetic stimulation of the retrotrapezoid nucleus in sleeping rats activates breathing without changing blood pressure or causing arousal or sighs. J Appl Physiol (1985) (2015) 0.75
Cardiac diastolic and autonomic dysfunction are aggravated by central chemoreflex activation in heart failure with preserved ejection fraction rats. J Physiol (2017) 0.75
Patterns of Brain Activation and Meal Reduction Induced by Abdominal Surgery in Mice and Modulation by Rikkunshito. PLoS One (2015) 0.75
C1 neurons mediate a stress-induced anti-inflammatory reflex in mice. Nat Neurosci (2017) 0.75
Is plasticity within the retrotrapezoid nucleus responsible for the recovery of the PCO2 set-point after carotid body denervation in rats? J Physiol (2016) 0.75
Catecholaminergic A1/C1 neurons contribute to the maintenance of upper airway muscle tone but may not participate in NREM sleep-related depression of these muscles. Respir Physiol Neurobiol (2017) 0.75
Arcuate neuropeptide Y inhibits sympathetic nerve activity via multiple neuropathways. J Clin Invest (2017) 0.75
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature (2003) 16.48
Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature (2009) 11.74
The sympathetic control of blood pressure. Nat Rev Neurosci (2006) 6.44
The expression of vesicular glutamate transporters defines two classes of excitatory synapse. Neuron (2001) 4.97
Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nat Protoc (2010) 3.71
Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits. Nat Protoc (2011) 2.90
Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons. J Neurosci (2008) 2.81
A barometric method for measuring ventilation in newborn infants. Pediatrics (1955) 2.69
Long-term telemetric measurement of cardiovascular parameters in awake mice: a physiological genomics tool. Physiol Genomics (2001) 2.58
A neural circuit for circadian regulation of arousal. Nat Neurosci (2001) 2.43
Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci (2009) 2.36
Central pathways of pulmonary and lower airway vagal afferents. J Appl Physiol (1985) (2006) 2.17
Central respiratory chemoreception. J Comp Neurol (2010) 2.06
Electrophysiological study of cardiovascular neurons in the rostral ventrolateral medulla in rats. Circ Res (1985) 1.73
The yin and yang of cardiac autonomic control: vago-sympathetic interactions revisited. Brain Res Brain Res Rev (2005) 1.64
Efferent projections of rat rostroventrolateral medulla C1 catecholamine neurons: Implications for the central control of cardiovascular regulation. J Comp Neurol (2006) 1.64
Essential role of Phox2b-expressing ventrolateral brainstem neurons in the chemosensory control of inspiration and expiration. J Neurosci (2010) 1.62
Identification of C1 presympathetic neurons in rat rostral ventrolateral medulla by juxtacellular labeling in vivo. J Comp Neurol (1997) 1.60
Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia. J Comp Neurol (1997) 1.56
Hypoxia and electrical stimulation of the carotid sinus nerve induce Fos-like immunoreactivity within catecholaminergic and serotoninergic neurons of the rat brainstem. J Comp Neurol (1994) 1.56
Vesicular glutamate transporter DNPI/VGLUT2 mRNA is present in C1 and several other groups of brainstem catecholaminergic neurons. J Comp Neurol (2002) 1.54
Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice. J Comp Neurol (2009) 1.52
The dorsomedial hypothalamus and the response to stress: part renaissance, part revolution. Pharmacol Biochem Behav (2002) 1.45
Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats. J Physiol (2009) 1.40
Subgroups of hindbrain catecholamine neurons are selectively activated by 2-deoxy-D-glucose induced metabolic challenge. Brain Res (1998) 1.37
Control of breathing by raphe obscurus serotonergic neurons in mice. J Neurosci (2011) 1.36
The role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulation. J Appl Physiol (1985) (2010) 1.33
Central chemoreceptors and sympathetic vasomotor outflow. J Physiol (2006) 1.32
Central nervous system distribution of the transcription factor Phox2b in the adult rat. J Comp Neurol (2007) 1.29
Respiratory sinus arrhythmia. A phenomenon improving pulmonary gas exchange and circulatory efficiency. Circulation (1996) 1.29
Locus coeruleus noradrenergic neurons and CO2 drive to breathing. Pflugers Arch (2007) 1.22
Respiratory rhythm entrainment by somatic afferent stimulation. J Neurosci (2005) 1.19
Functional organization of the parabrachial complex and intertrigeminal region in the control of breathing. Respir Physiol Neurobiol (2004) 1.19
Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats. J Neurosci (2011) 1.16
Monosynaptic projections from the nucleus tractus solitarii to C1 adrenergic neurons in the rostral ventrolateral medulla: comparison with input from the caudal ventrolateral medulla. J Comp Neurol (1996) 1.13
Antagonism of rat orexin receptors by almorexant attenuates central chemoreception in wakefulness in the active period of the diurnal cycle. J Physiol (2010) 1.12
Sources of inputs to the anterior and posterior aspects of the paraventricular nucleus of the thalamus. Brain Struct Funct (2011) 1.11
An intracellular study of respiratory neurons in the rostral ventrolateral medulla of the rat and their relationship to catecholamine-containing neurons. J Comp Neurol (1990) 1.11
Specificity and generality of the involvement of catecholaminergic afferents in hypothalamic responses to immune insults. J Comp Neurol (2007) 1.10
Topographic organization of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus in the rat. J Comp Neurol (1992) 1.09
Hypoxia-induced Fos expression in neurons projecting to the pressor region in the rostral ventrolateral medulla. Neuroscience (1997) 1.08
Protective role of neuronal KATP channels in brain hypoxia. J Exp Biol (2004) 1.08
Control of sympathetic vasomotor tone by catecholaminergic C1 neurones of the rostral ventrolateral medulla oblongata. Cardiovasc Res (2011) 1.06
Pharmacology of reticulospinal vasomotor neurons in cardiovascular regulation. Pharmacol Rev (1996) 1.03
Central chemoreception in wakefulness and sleep: evidence for a distributed network and a role for orexin. J Appl Physiol (1985) (2010) 1.02
Barosensitive neurons in the rostral ventrolateral medulla of the rat in vivo: morphological properties and relationship to C1 adrenergic neurons. Neuroscience (1995) 0.99
Chemosensory pathways in the brainstem controlling cardiorespiratory activity. Philos Trans R Soc Lond B Biol Sci (2009) 0.99
Nature of differential sympathetic discharges in chemoreceptor reflexes. Proc Natl Acad Sci U S A (1978) 0.97
Possible modulation of the mouse respiratory rhythm generator by A1/C1 neurones. Respir Physiol Neurobiol (2005) 0.97
Carotid chemoreflex. Neural pathways and transmitters. Adv Exp Med Biol (1996) 0.96
Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. J Neurosci (2009) 0.96
Evaluating the physiological significance of respiratory sinus arrhythmia: looking beyond ventilation-perfusion efficiency. J Physiol (2012) 0.94
Functional anatomy of sympathetic premotor cell groups in the medulla. Clin Exp Hypertens (1995) 0.94
Chemoreceptor-sensitive neurons in commissural subnucleus of nucleus tractus solitarius of the rat. Am J Physiol (1995) 0.94
Glutamatergic neurotransmission between the C1 neurons and the parasympathetic preganglionic neurons of the dorsal motor nucleus of the vagus. J Neurosci (2013) 0.93
Nociceptive inputs into rostral ventrolateral medulla-spinal vasomotor neurones in rats. J Physiol (1991) 0.91
ATP in central respiratory control: a three-part signaling system. Respir Physiol Neurobiol (2008) 0.90
Responses of rostroventrolateral medulla spinal vasomotor neurones to chemoreceptor stimulation in rats. J Auton Nerv Syst (1991) 0.88
Functional significance of coactivation of vagal and sympathetic cardiac nerves. Proc Natl Acad Sci U S A (1982) 0.87
Cholinergic neurons in the mouse rostral ventrolateral medulla target sensory afferent areas. Brain Struct Funct (2012) 0.85
Differential chemoreceptor reflex responses of adrenal preganglionic neurons. Am J Physiol Regul Integr Comp Physiol (2001) 0.84
Neural control of the heart: significance of double innervation re-examined. J Auton Nerv Syst (1983) 0.84
Hypothalamic modulation of breathing. Adv Exp Med Biol (2010) 0.83
Medullary vasomotor activity and hypoxic sympathoexcitation in pentobarbital-anesthetized rats. Am J Physiol (1996) 0.82
Acute vagal stimulation attenuates cardiac metabolic response to β-adrenergic stress. J Physiol (2012) 0.82
The effects of baroreceptor stimulation on central respiratory drive: a review. Respir Physiol Neurobiol (2010) 0.81
Catecholaminergic neurons in the ventrolateral medulla and nucleus of the solitary tract in the human. J Comp Neurol (1988) 0.79
Organization of presumptive catecholamine-synthesizing neurons in the canine medulla oblongata. Brain Res (1993) 0.76
The distribution of tyrosine hydroxylase, dopamine-beta-hydroxylase, and phenylethanolamine-N-methyltransferase immunoreactive neurons in the feline medulla oblongata. J Comp Neurol (1986) 0.76
Presumptive adrenergic neurons containing phenylethanolamine N-methyltransferase immunoreactivity in the medulla oblongata of neonatal swine. Brain Res (1992) 0.76
Defining a link with asthma in mice congenitally deficient in eosinophils. Science (2004) 5.20
Respiratory control by ventral surface chemoreceptor neurons in rats. Nat Neurosci (2004) 4.87
Wild-type microglia arrest pathology in a mouse model of Rett syndrome. Nature (2012) 3.83
Expression of Phox2b by brainstem neurons involved in chemosensory integration in the adult rat. J Neurosci (2006) 2.42
Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats. J Neurosci (2009) 2.36
Peripheral chemoreceptor inputs to retrotrapezoid nucleus (RTN) CO2-sensitive neurons in rats. J Physiol (2006) 2.31
TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. J Neurosci (2007) 2.20
Demand-supply of neurointerventionalists for endovascular ischemic stroke therapy. Neurology (2012) 2.07
Central respiratory chemoreception. J Comp Neurol (2010) 2.06
Pivotal Advance: eosinophil infiltration of solid tumors is an early and persistent inflammatory host response. J Leukoc Biol (2006) 2.06
Regulation of ventral surface chemoreceptors by the central respiratory pattern generator. J Neurosci (2005) 2.02
The organization of two new cortical interneuronal circuits. Nat Neurosci (2013) 1.96
State-dependent Ras signaling and AMPA receptor trafficking. Genes Dev (2005) 1.86
Afferent and efferent connections of the rat retrotrapezoid nucleus. J Comp Neurol (2006) 1.86
A group of glutamatergic interneurons expressing high levels of both neurokinin-1 receptors and somatostatin identifies the region of the pre-Bötzinger complex. J Comp Neurol (2003) 1.85
Serotonergic neurons activate chemosensitive retrotrapezoid nucleus neurons by a pH-independent mechanism. J Neurosci (2007) 1.68
Water deprivation activates a glutamatergic projection from the hypothalamic paraventricular nucleus to the rostral ventrolateral medulla. J Comp Neurol (2006) 1.62
Mitral apparatus assessment by delayed enhancement CMR: relative impact of infarct distribution on mitral regurgitation. JACC Cardiovasc Imaging (2013) 1.58
Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes. J Clin Invest (2016) 1.56
Retrotrapezoid nucleus and central chemoreception. J Physiol (2008) 1.54
Vesicular glutamate transporter DNPI/VGLUT2 mRNA is present in C1 and several other groups of brainstem catecholaminergic neurons. J Comp Neurol (2002) 1.54
Longitudinal relationship between physical activity and lung health in patients with cystic fibrosis. Eur Respir J (2013) 1.53
Acid sensitivity and ultrastructure of the retrotrapezoid nucleus in Phox2b-EGFP transgenic mice. J Comp Neurol (2009) 1.52
Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors. Exp Physiol (2005) 1.51
Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2. J Comp Neurol (2003) 1.48
Chandelier cells control excessive cortical excitation: characteristics of whisker-evoked synaptic responses of layer 2/3 nonpyramidal and pyramidal neurons. J Neurosci (2004) 1.48
Vesicular glutamate transporter 2 is required for the respiratory and parasympathetic activation produced by optogenetic stimulation of catecholaminergic neurons in the rostral ventrolateral medulla of mice in vivo. Eur J Neurosci (2013) 1.48
Selective lesion of retrotrapezoid Phox2b-expressing neurons raises the apnoeic threshold in rats. J Physiol (2008) 1.46
The baroreflex and beyond: control of sympathetic vasomotor tone by GABAergic neurons in the ventrolateral medulla. Clin Exp Pharmacol Physiol (2002) 1.41
Purinergic P2 receptors modulate excitability but do not mediate pH sensitivity of RTN respiratory chemoreceptors. J Neurosci (2006) 1.40
Photostimulation of channelrhodopsin-2 expressing ventrolateral medullary neurons increases sympathetic nerve activity and blood pressure in rats. J Physiol (2009) 1.40
Synaptic AMPA receptor exchange maintains bidirectional plasticity. Neuron (2006) 1.40
Serotonergic raphe neurons express TASK channel transcripts and a TASK-like pH- and halothane-sensitive K+ conductance. J Neurosci (2002) 1.39
Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic. J Neurosci (2002) 1.39
Contrast-enhanced magnetic resonance angiography of carotid arteries: utility in routine clinical practice. Stroke (2002) 1.38
Immunohistochemical localization of GAD67-expressing neurons and processes in the rat brainstem: subregional distribution in the nucleus tractus solitarius. J Comp Neurol (2005) 1.37
Control of breathing by raphe obscurus serotonergic neurons in mice. J Neurosci (2011) 1.36
Central chemoreceptors and sympathetic vasomotor outflow. J Physiol (2006) 1.32
Cardiorespiratory neurons of the rat ventrolateral medulla contain TASK-1 and TASK-3 channel mRNA. Respir Physiol Neurobiol (2003) 1.28
Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma--the University of Iowa experience. Int J Radiat Oncol Biol Phys (2005) 1.25
Botzinger expiratory-augmenting neurons and the parafacial respiratory group. J Neurosci (2008) 1.25
Vesicular glutamate transporter DNPI/VGLUT2 is expressed by both C1 adrenergic and nonaminergic presympathetic vasomotor neurons of the rat medulla. J Comp Neurol (2002) 1.25
Paper-based microfluidic devices by plasma treatment. Anal Chem (2008) 1.23
Optogenetic stimulation of c1 and retrotrapezoid nucleus neurons causes sleep state-dependent cardiorespiratory stimulation and arousal in rats. Hypertension (2013) 1.23
Optic nerve diffusion changes and atrophy jointly predict visual dysfunction after optic neuritis. Neuroimage (2009) 1.22
Central CO2 chemoreception and integrated neural mechanisms of cardiovascular and respiratory control. J Appl Physiol (1985) (2010) 1.20
In vivo quantification of contrast agent concentration using the induced magnetic field for time-resolved arterial input function measurement with MRI. Med Phys (2008) 1.19
C1 neurons: the body's EMTs. Am J Physiol Regul Integr Comp Physiol (2013) 1.19
Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats. Am J Respir Crit Care Med (2010) 1.17
Phox2b-expressing neurons of the parafacial region regulate breathing rate, inspiration, and expiration in conscious rats. J Neurosci (2011) 1.16
Baro-activated neurons with pulse-modulated activity in the rat caudal ventrolateral medulla express GAD67 mRNA. J Neurophysiol (2002) 1.15
Inhibitory input from slowly adapting lung stretch receptors to retrotrapezoid nucleus chemoreceptors. J Physiol (2007) 1.14
A cost-utility and cost-effectiveness analysis of an acute pain service. J Clin Anesth (2004) 1.11
Pre-Bötzinger complex receives glutamatergic innervation from galaninergic and other retrotrapezoid nucleus neurons. J Comp Neurol (2012) 1.11
Retrotrapezoid nucleus, respiratory chemosensitivity and breathing automaticity. Respir Physiol Neurobiol (2009) 1.10
Coexpression of vesicular glutamate transporter-3 and gamma-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column. J Comp Neurol (2005) 1.10
Fos expression by glutamatergic neurons of the solitary tract nucleus after phenylephrine-induced hypertension in rats. J Comp Neurol (2003) 1.10
The spectrum of central nervous system infections in an adult referral hospital in Hanoi, Vietnam. PLoS One (2012) 1.09
Anesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K(+) current. J Neurosci (2010) 1.09
Higher volume endovascular stroke centers have faster times to treatment, higher reperfusion rates and higher rates of good clinical outcomes. J Neurointerv Surg (2012) 1.09
Depressor and tachypneic responses to chemical stimulation of the ventral respiratory group are reduced by ablation of neurokinin-1 receptor-expressing neurons. J Neurosci (2002) 1.08
Activation of the retrotrapezoid nucleus by posterior hypothalamic stimulation. J Physiol (2009) 1.07
Phox2b-expressing retrotrapezoid neurons are intrinsically responsive to H+ and CO2. J Neurosci (2013) 1.06
TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons. J Neurosci (2013) 1.03
Changing failure patterns in oropharyngeal squamous cell carcinoma treated with intensity modulated radiotherapy and implications for future research. Am J Clin Oncol (2006) 1.03
Glutamatergic neuronal projections from the marginal layer of the rostral ventral medulla to the respiratory centers in rats. J Comp Neurol (2004) 1.02
Adenovirus encoding human platelet-derived growth factor-B delivered in collagen exhibits safety, biodistribution, and immunogenicity profiles favorable for clinical use. Mol Ther (2004) 1.01
Physical activity in Ontario preschoolers: prevalence and measurement issues. Appl Physiol Nutr Metab (2011) 1.00
Inspiratory augmenting bulbospinal neurons express both glutamatergic and enkephalinergic phenotypes. J Comp Neurol (2003) 0.97
Exercise and physical activity in children with cystic fibrosis. Paediatr Respir Rev (2009) 0.97
GABAergic and glycinergic presympathetic neurons of rat medulla oblongata identified by retrograde transport of pseudorabies virus and in situ hybridization. J Comp Neurol (2004) 0.97
GABAergic neurons in the central region of the spinal cord: a novel substrate for sympathetic inhibition. J Neurosci (2005) 0.96
GABAergic pump cells of solitary tract nucleus innervate retrotrapezoid nucleus chemoreceptors. J Neurophysiol (2007) 0.96
Door-to-puncture: a practical metric for capturing and enhancing system processes associated with endovascular stroke care, preliminary results from the rapid reperfusion registry. J Am Heart Assoc (2014) 0.95
Sodium selenate specifically activates PP2A phosphatase, dephosphorylates tau and reverses memory deficits in an Alzheimer's disease model. J Clin Neurosci (2010) 0.95