CHD6, a cellular repressor of influenza virus replication, is degraded in human alveolar epithelial cells and mice lungs during infection.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3624387)

Published in J Virol on February 13, 2013

Authors

Roberto Alfonso1, Ariel Rodriguez, Paloma Rodriguez, Thomas Lutz, Amelia Nieto

Author Affiliations

1: Centro Nacional de Biotecnología, Darwin 3, Cantoblanco, Madrid, Spain.

Articles cited by this

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc Natl Acad Sci U S A (1979) 21.22

The biology of chromatin remodeling complexes. Annu Rev Biochem (2009) 10.02

A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. Cell (1981) 8.09

Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. Mol Cell (1998) 5.60

Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins. Proc Natl Acad Sci U S A (1981) 5.57

Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature (2005) 5.53

Determination of influenza virus proteins required for genome replication. J Virol (1990) 4.36

Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem (2005) 4.20

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev (2001) 3.67

Evaluation of a genetically modified reassortant H5N1 influenza A virus vaccine candidate generated by plasmid-based reverse genetics. Virology (2003) 3.49

Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery. EMBO J (1999) 3.35

Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J (1994) 3.26

Inhibition of Ran guanosine triphosphatase-dependent nuclear transport by the matrix protein of vesicular stomatitis virus. Science (1997) 2.72

Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol Cell Biol (2000) 2.48

Transcription and replication of nonsegmented negative-strand RNA viruses. Curr Top Microbiol Immunol (2004) 2.41

NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase. J Virol (2009) 2.39

E2F - at the crossroads of life and death. Trends Cell Biol (2008) 2.37

Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol (2002) 2.31

Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3. Proc Natl Acad Sci U S A (2005) 2.30

The structure of a biologically active influenza virus ribonucleoprotein complex. PLoS Pathog (2009) 2.23

Cellular networks involved in the influenza virus life cycle. Cell Host Microbe (2010) 2.23

Influenza virus gene expression: control mechanisms at early and late times of infection and nuclear-cytoplasmic transport of virus-specific RNAs. J Virol (1987) 2.21

The three influenza virus polymerase (P) proteins not associated with viral nucleocapsids in the infected cell are in the form of a complex. J Virol (1987) 2.20

Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II. J Virol (2005) 2.19

Influenza virus RNA is synthesized at fixed sites in the nucleus. Nature (1982) 2.18

Heterochromatin silencing of p53 target genes by a small viral protein. Nature (2010) 2.12

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. EMBO J (2005) 2.12

Cell cycle regulation of PML modification and ND10 composition. J Cell Sci (1999) 2.04

Distinct regions of influenza virus PB1 polymerase subunit recognize vRNA and cRNA templates. EMBO J (1999) 2.00

PA subunit from influenza virus polymerase complex interacts with a cellular protein with homology to a family of transcriptional activators. J Virol (2001) 1.98

Metabolism and expression of RNA polymerase II transcripts in influenza virus-infected cells. Mol Cell Biol (1984) 1.97

Monoclonal antibodies against influenza virus PB2 and NP polypeptides interfere with the initiation step of viral mRNA synthesis in vitro. J Virol (1994) 1.93

Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein. J Virol (2004) 1.88

Spliced and unspliced messenger RNAs synthesized from cloned influenza virus M DNA in an SV40 vector: expression of the influenza virus membrane protein (M1). Virology (1982) 1.87

Inhibition of host protein synthesis and degradation of cellular mRNAs during infection by influenza and herpes simplex virus. Mol Cell Biol (1982) 1.86

Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins. J Virol (2000) 1.78

Transcription of a recombinant influenza virus RNA in cells that can express the influenza virus RNA polymerase and nucleoprotein genes. J Gen Virol (1992) 1.75

Influenza virus naked RNA can be expressed upon transfection into cells co-expressing the three subunits of the polymerase and the nucleoprotein from simian virus 40 recombinant viruses. J Gen Virol (1993) 1.74

Trials in man with live recombinants made from A/PR/8/34 (H0 N1) and wild H3 N2 influenza viruses. Lancet (1975) 1.74

The large P proteins of influenza A viruses are composed of one acidic and two basic polypeptides. Virology (1980) 1.71

Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo. Mol Cell Biol (2005) 1.64

Influenza virus infection causes specific degradation of the largest subunit of cellular RNA polymerase II. J Virol (2007) 1.64

Analysis of the interaction of influenza virus polymerase complex with human cell factors. Proteomics (2008) 1.64

Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus. J Virol (1986) 1.59

Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA. J Virol Methods (2010) 1.53

Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses. J Virol (2003) 1.50

A live attenuated cold-adapted influenza A H7N3 virus vaccine provides protection against homologous and heterologous H7 viruses in mice and ferrets. Virology (2008) 1.48

Proteasome-dependent, ubiquitin-independent degradation of Daxx by the viral pp71 protein in human cytomegalovirus-infected cells. Virology (2007) 1.48

Inhibition of host RNA polymerase II-dependent transcription by vesicular stomatitis virus results from inactivation of TFIID. Virology (1998) 1.44

NSs protein of rift valley fever virus promotes posttranslational downregulation of the TFIIH subunit p62. J Virol (2011) 1.41

The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity. J Virol (2007) 1.38

Nuclear export of influenza A virus mRNAs requires ongoing RNA polymerase II activity. Traffic (2006) 1.36

Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5'-untranslated region. J Biol Chem (1993) 1.29

Rapid inhibition of processing and assembly of small nuclear ribonucleoproteins after infection with vesicular stomatitis virus. Mol Cell Biol (1987) 1.29

Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells. Virology (2009) 1.27

The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation. Mol Cell Biol (2005) 1.26

The synthesis of influenza virus negative-strand RNA takes place in insoluble complexes present in the nuclear matrix fraction. Virus Res (1990) 1.24

Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins. MBio (2011) 1.22

Interaction of influenza virus proteins with nucleosomes. Virology (2005) 1.21

Nrf2 expression modifies influenza A entry and replication in nasal epithelial cells. Free Radic Biol Med (2011) 1.21

A novel spliced transcript of influenza A/WSN/33 virus. Virus Genes (1998) 1.21

Degradation of cellular mRNA during influenza virus infection: its possible role in protein synthesis shutoff. J Gen Virol (1992) 1.19

Alterations in nuclear matrix structure after adenovirus infection. J Virol (1987) 1.18

Rhabdovirus evasion of the interferon system. J Interferon Cytokine Res (2009) 1.11

Host factor Ebp1: selective inhibitor of influenza virus transcriptase. Genes Cells (2007) 1.11

Evaluation of live attenuated influenza a virus h6 vaccines in mice and ferrets. J Virol (2008) 1.10

CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis. FEBS Lett (2006) 1.10

Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells. Virology (2010) 1.09

hCLE/CGI-99, a human protein that interacts with the influenza virus polymerase, is a mRNA transcription modulator. J Mol Biol (2006) 1.05

Inhibition of cellular DNA synthesis by vesicular stomatitis virus. J Virol (1981) 1.04

Attenuated strains of influenza A viruses do not induce degradation of RNA polymerase II. J Virol (2009) 1.01

Protein synthesis shut-off induced by influenza virus infection is independent of PKR activity. J Virol (2000) 1.00

Role of host protein Ebp1 in influenza virus growth: intracellular localization of Ebp1 in virus-infected and uninfected cells. J Biotechnol (2007) 0.96

Association of functional influenza viral proteins and RNAs with nuclear chromatin and sub-chromatin structure. Microbes Infect (2006) 0.96

Role of Itk signalling in the interaction between influenza A virus and T-cells. J Gen Virol (2012) 0.95

Cyclin T1/CDK9 interacts with influenza A virus polymerase and facilitates its association with cellular RNA polymerase II. J Virol (2010) 0.94

Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription. Virology (2009) 0.93

Cytoplasmic and nuclear input virus RNPs in influenza virus-infected cells. J Gen Virol (1979) 0.91

CHD6 chromatin remodeler is a negative modulator of influenza virus replication that relocates to inactive chromatin upon infection. Cell Microbiol (2011) 0.90

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. PLoS Pathog (2011) 0.90

Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication. J Virol (2011) 0.89

Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection. J Virol (2011) 0.88

Regulation of STAT signaling in mouse bone marrow derived dendritic cells by respiratory syncytial virus. Virus Res (2011) 0.84

Cyclophilin E functions as a negative regulator to influenza virus replication by impairing the formation of the viral ribonucleoprotein complex. PLoS One (2011) 0.83

Interaction of the papillomavirus E8--E2C protein with the cellular CHD6 protein contributes to transcriptional repression. J Virol (2010) 0.81

Cellular protein HAX1 interacts with the influenza A virus PA polymerase subunit and impedes its nuclear translocation. J Virol (2012) 0.80

Regulation of promyelocytic leukemia (PML) protein levels and cell morphology by bovine herpesvirus 1 infected cell protein 0 (bICP0) and mutant bICP0 proteins that do not localize to the nucleus. Virus Res (2011) 0.77

Articles by these authors

Nevirapine versus atazanavir/ritonavir, each combined with tenofovir disoproxil fumarate/emtricitabine, in antiretroviral-naive HIV-1 patients: the ARTEN Trial. Antivir Ther (2011) 1.90

Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein. J Virol (2004) 1.88

Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir. Antivir Ther (2005) 1.85

Combination of tenofovir and lamivudine versus tenofovir after lamivudine failure for therapy of hepatitis B in HIV-coinfection. AIDS (2006) 1.68

PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes. J Gen Virol (2003) 1.65

Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett (2005) 1.59

ISG15 regulates peritoneal macrophages functionality against viral infection. PLoS Pathog (2013) 1.51

Threonine 157 of influenza virus PA polymerase subunit modulates RNA replication in infectious viruses. J Virol (2003) 1.50

Acute metabolic acidosis: characterization and diagnosis of the disorder and the plasma potassium response. J Am Soc Nephrol (2004) 1.44

Snapshots: chromatin control of viral infection. Virology (2013) 1.39

Characterization in vitro and in vivo of a pandemic H1N1 influenza virus from a fatal case. PLoS One (2013) 1.30

Brief Report: Dolutegravir Plus Abacavir/Lamivudine for the Treatment of HIV-1 Infection in Antiretroviral Therapy-Naive Patients: Week 96 and Week 144 Results From the SINGLE Randomized Clinical Trial. J Acquir Immune Defic Syndr (2015) 1.28

Vagal sparing surgical technique but not stoma size affects body weight loss in rodent model of gastric bypass. Obes Surg (2010) 1.20

The effect of using standardized patients or peer role play on ratings of undergraduate communication training: a randomized controlled trial. Patient Educ Couns (2011) 1.17

Influenza virus mRNA translation revisited: is the eIF4E cap-binding factor required for viral mRNA translation? J Virol (2007) 1.15

Characterization of white matter alterations in phenylketonuria by magnetic resonance relaxometry and diffusion tensor imaging. Magn Reson Med (2007) 1.14

CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis. FEBS Lett (2006) 1.10

Pegylated interferon-alpha for the treatment of sexually transmitted acute hepatitis C in HIV-infected individuals. Antivir Ther (2006) 1.09

Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults. Eur J Clin Pharmacol (2007) 1.09

A non-essential function for yeast frataxin in iron-sulfur cluster assembly. Hum Mol Genet (2002) 1.08

Hindbrain noradrenergic input to the hypothalamic PVN mediates the activation of oxytocinergic neurons induced by the satiety factor oleoylethanolamide. Am J Physiol Endocrinol Metab (2013) 1.07

Impact of tenofovir-containing antiretroviral therapy on chronic hepatitis B in a cohort co-infected with human immunodeficiency virus. J Antimicrob Chemother (2005) 1.06

HIV and cancer in Germany. Dtsch Arztebl Int (2011) 1.05

hCLE/CGI-99, a human protein that interacts with the influenza virus polymerase, is a mRNA transcription modulator. J Mol Biol (2006) 1.05

Attenuated strains of influenza A viruses do not induce degradation of RNA polymerase II. J Virol (2009) 1.01

Saquinavir drug exposure is not impaired by the boosted double protease inhibitor combination of lopinavir/ritonavir. AIDS (2004) 1.00

Sepiapterin reductase deficiency: a treatable mimic of cerebral palsy. Ann Neurol (2012) 1.00

Hypertrophy dependent doubling of L-cells in Roux-en-Y gastric bypass operated rats. PLoS One (2013) 0.99

Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers. BMC Gastroenterol (2012) 0.95

Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIV-positive patients with acute and chronic hepatitis C. J Infect Dis (2011) 0.94

Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers. Hepatology (2013) 0.92

Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients. Hepatology (2007) 0.92

Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy. Pediatr Neurol (2006) 0.90

CHD6 chromatin remodeler is a negative modulator of influenza virus replication that relocates to inactive chromatin upon infection. Cell Microbiol (2011) 0.90

Molecular analysis of an HBsAg-negative hepatitis B virus mutant selected in a tenofovir-treated HIV-hepatitis B virus co-infected patient. AIDS (2009) 0.90

So similar, yet so different: selective translation of capped and polyadenylated viral mRNAs in the influenza virus infected cell. Virus Res (2010) 0.89

Diagnostic performance of rapid influenza antigen assays in patients infected with the new influenza A (H1N1) virus. Clin Chem Lab Med (2010) 0.89

Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication. J Virol (2011) 0.89

Pharmacokinetics of saquinavir, atazanavir, and ritonavir in a twice-daily boosted double-protease inhibitor regimen. Antimicrob Agents Chemother (2007) 0.88

Ghrelin-induced hypothermia: a physiological basis but no clinical risk. Physiol Behav (2011) 0.86

Littoral cell angioma in main and accessory intrapancreatic spleen presenting as splenic rupture. Am J Surg (2010) 0.86

Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation. Virology (2011) 0.83

Daily dosing of tacrolimus in patients treated with HIV-1 therapy containing a ritonavir-boosted protease inhibitor or raltegravir. J Antimicrob Chemother (2010) 0.81

Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation. Virology (2011) 0.81

Characterization of an enhanced antigenic change in the pandemic 2009 H1N1 influenza virus haemagglutinin. J Gen Virol (2014) 0.80

Noncompliance with guidelines for the treatment of hepatitis C is frequent in daily practice. Eur J Gastroenterol Hepatol (2014) 0.79

Nitric oxide directly inhibits ghrelin-activated neurons of the arcuate nucleus. Brain Res (2006) 0.79

Deletion of the Chd6 exon 12 affects motor coordination. Mamm Genome (2010) 0.79

Demonstration of spectral correlation control in a source of polarization-entangled photon pairs at telecom wavelength. Opt Lett (2014) 0.78

The cytotoxic lymphocyte antigen 4 polymorphisms affect response to hepatitis C virus-specific therapy in HIV(+) patients with acute and chronic hepatitis C virus co-infection. AIDS (2010) 0.78

Safety and Efficacy in HIV-1-Infected Patients Treated with Ritonavir-Boosted Saquinavir Mesylate. Arch Drug Inf (2010) 0.76

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection. PLoS Pathog (2016) 0.75

Exploring the moderating role of context on the mathematics performance of females under stereotype threat: a meta-analysis. J Soc Psychol (2013) 0.75

Dual treatment of acute HCV infection in HIV co-infection: influence of HCV genotype upon treatment outcome. Infection (2016) 0.75

Long-term effect on body composition and metabolic parameters after treatment with recombinant human growth hormone (r-hGH) in HIV-1 infected patients with lipodystrophy. Scand J Infect Dis (2007) 0.75

Visibility of vascular phenylalanine in dynamic uptake studies in humans using magnetic resonance spectroscopy. Magn Reson Med (2005) 0.75

Editorial: Physiology & Behavior. Physiol Behav (2015) 0.75

Handlebar injuries in children. Pediatr Surg Int (2012) 0.75

Enterostatin decreases postprandial pancreatic UCP2 mRNA levels and increases plasma insulin and amylin. Am J Physiol Endocrinol Metab (2005) 0.75

Haemolytic anaemia after nucleotide antiretroviral treatment discontinuation in a chronic hepatitis B-virus co-infected AIDS patient. AIDS (2004) 0.75

Impact of IL28B genotype on first-week response to telaprevir-based therapy in HIV-HCV coinfection. Antivir Ther (2014) 0.75