Published in Biophys J on February 05, 2013
Lipid landscapes and pipelines in membrane homeostasis. Nature (2014) 2.09
Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3. Nat Cell Biol (2014) 1.46
Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature. Biophys J (2013) 1.10
Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization. PLoS One (2014) 0.96
Molecular modeling of lipid membrane curvature induction by a peptide: more than simply shape. Biophys J (2014) 0.95
Membrane tension controls the assembly of curvature-generating proteins. Nat Commun (2015) 0.92
Sensing membrane stresses by protein insertions. PLoS Comput Biol (2014) 0.92
Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport. Elife (2015) 0.92
The seipin complex Fld1/Ldb16 stabilizes ER-lipid droplet contact sites. J Cell Biol (2015) 0.91
When Physics Takes Over: BAR Proteins and Membrane Curvature. Trends Cell Biol (2015) 0.91
The SNARE motif of synaptobrevin exhibits an aqueous-interfacial partitioning that is modulated by membrane curvature. Biochemistry (2014) 0.88
Insertion of the Ca²⁺-independent phospholipase A₂ into a phospholipid bilayer via coarse-grained and atomistic molecular dynamics simulations. PLoS Comput Biol (2013) 0.88
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein. Proc Natl Acad Sci U S A (2016) 0.83
An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions. J Biol Chem (2015) 0.81
A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition. Elife (2016) 0.80
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory. J Membr Biol (2015) 0.79
Conserved Amphipathic Helices Mediate Lipid Droplet Targeting of Perilipins 1-3. J Biol Chem (2016) 0.79
Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein. Biochim Biophys Acta (2016) 0.78
Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone. PLoS One (2015) 0.77
Curvature sensing MARCKS-ED peptides bind to membranes in a stereo-independent manner. J Pept Sci (2015) 0.77
New and notable: key new insights into membrane targeting by proteins. Biophys J (2013) 0.77
Mechanisms of Autophagy Initiation. Annu Rev Biochem (2017) 0.76
An investigation of the effect of membrane curvature on transmembrane-domain dependent protein sorting in lipid bilayers. Cell Logist (2014) 0.76
Recursive Alterations of the Relationship between Simple Membrane Geometry and Insertion of Amphiphilic Motifs. Membranes (Basel) (2017) 0.75
Interdigitation between Triglycerides and Lipids Modulates Surface Properties of Lipid Droplets. Biophys J (2017) 0.75
Determinants of Curvature-Sensing Behavior for MARCKS-Fragment Peptides. Biophys J (2016) 0.75
Reovirus FAST Proteins Drive Pore Formation and Syncytiogenesis Using a Novel Helix-Loop-Helix Fusion-Inducing Lipid Packing Sensor. PLoS Pathog (2015) 0.75
The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport. Oncotarget (2016) 0.75
Amphipathic Helices-Wedge? Or Nae Nae? Biophys J (2016) 0.75
VMD: visual molecular dynamics. J Mol Graph (1996) 117.02
GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation. J Chem Theory Comput (2008) 34.90
Antimicrobial peptides of multicellular organisms. Nature (2002) 23.50
Canonical sampling through velocity rescaling. J Chem Phys (2007) 12.40
Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature (2005) 10.04
Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys J (1997) 9.60
How proteins produce cellular membrane curvature. Nat Rev Mol Cell Biol (2006) 6.90
How lipids affect the activities of integral membrane proteins. Biochim Biophys Acta (2004) 4.88
A general amphipathic alpha-helical motif for sensing membrane curvature. Nat Struct Mol Biol (2007) 3.69
Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature. Nature (2003) 3.48
Hydrophobic interactions of peptides with membrane interfaces. Biochim Biophys Acta (1998) 2.79
Distribution of amino acids in a lipid bilayer from computer simulations. Biophys J (2008) 2.53
Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L). Proc Natl Acad Sci U S A (2011) 2.46
How curved membranes recruit amphipathic helices and protein anchoring motifs. Nat Chem Biol (2009) 2.38
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif. EMBO J (2005) 2.37
Membrane curvature controls dynamin polymerization. Proc Natl Acad Sci U S A (2010) 2.25
Mechanisms of membrane curvature sensing. Annu Rev Biochem (2011) 2.19
Cell cycle-dependent differences in nuclear pore complex assembly in metazoa. Cell (2010) 2.12
Folding of amphipathic alpha-helices on membranes: energetics of helix formation by melittin. J Mol Biol (1999) 2.06
Asymmetric tethering of flat and curved lipid membranes by a golgin. Science (2008) 1.86
Thermodynamics and mechanics of membrane curvature generation and sensing by proteins and lipids. Annu Rev Phys Chem (2011) 1.66
Protein subcellular localization in bacteria. Cold Spring Harb Perspect Biol (2010) 1.62
Mechanism of membrane curvature sensing by amphipathic helix containing proteins. Biophys J (2011) 1.48
α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding. J Cell Biol (2011) 1.41
Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols. J Biol Chem (1997) 1.40
The N-terminus of the intrinsically disordered protein α-synuclein triggers membrane binding and helix folding. Biophys J (2010) 1.39
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature. Biochemistry (2007) 1.34
An iris-like mechanism of pore dilation in the CorA magnesium transport system. Biophys J (2010) 1.29
Membrane protein simulations with a united-atom lipid and all-atom protein model: lipid-protein interactions, side chain transfer free energies and model proteins. J Phys Condens Matter (2006) 1.28
A unifying mechanism accounts for sensing of membrane curvature by BAR domains, amphipathic helices and membrane-anchored proteins. Semin Cell Dev Biol (2009) 1.28
Membrane binding by the endophilin N-BAR domain. Biophys J (2009) 1.24
Membrane-bending mechanism of amphiphysin N-BAR domains. Biophys J (2009) 1.23
Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature. Biophys J (2013) 1.10
Mechanism and kinetics of peptide partitioning into membranes from all-atom simulations of thermostable peptides. J Am Chem Soc (2010) 1.09
Role of helix nucleation in the kinetics of binding of mastoparan X to phospholipid bilayers. Biochemistry (2007) 1.08
Comparative molecular dynamics simulations of the antimicrobial peptide CM15 in model lipid bilayers. Biochim Biophys Acta (2012) 0.92
Synapsin I senses membrane curvature by an amphipathic lipid packing sensor motif. J Neurosci (2011) 0.85
Amphipathic-Lipid-Packing-Sensor interactions with lipids assessed by atomistic molecular dynamics. Biochim Biophys Acta (2011) 0.84
Studies on viral fusion peptides: the distribution of lipophilic and electrostatic potential over the peptide determines the angle of insertion into a membrane. Eur Biophys J (2010) 0.78
A general amphipathic alpha-helical motif for sensing membrane curvature. Nat Struct Mol Biol (2007) 3.69
Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature. Nature (2003) 3.48
A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP. Cell (2013) 2.66
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif. EMBO J (2005) 2.37
HELIQUEST: a web server to screen sequences with specific alpha-helical properties. Bioinformatics (2008) 2.34
Amphipathic helices and membrane curvature. FEBS Lett (2009) 2.23
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol (2011) 2.22
Cargo selection into COPII vesicles is driven by the Sec24p subunit. EMBO J (2002) 2.20
Asymmetric tethering of flat and curved lipid membranes by a golgin. Science (2008) 1.86
Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity. Dev Cell (2012) 1.62
COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension. Proc Natl Acad Sci U S A (2008) 1.59
On the orientation of a designed transmembrane peptide: toward the right tilt angle? J Am Chem Soc (2007) 1.54
Determining membrane protein structures: still a challenge! Trends Biochem Sci (2007) 1.50
α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding. J Cell Biol (2011) 1.41
Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature. Biochemistry (2007) 1.34
Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop. J Biol Chem (2010) 1.28
The apparent cooperativity of some GPCRs does not necessarily imply dimerization. Trends Pharmacol Sci (2009) 1.27
Krit 1 interactions with microtubules and membranes are regulated by Rap1 and integrin cytoplasmic domain associated protein-1. FEBS J (2007) 1.25
ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions. EMBO J (2009) 1.21
Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature. Biophys J (2013) 1.10
A short survey on protein blocks. Biophys Rev (2010) 1.10
COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function. Proc Natl Acad Sci U S A (2013) 1.08
Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam. J Biol Chem (2002) 1.05
A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity. J Biol Chem (2004) 1.02
Genome adaptation to chemical stress: clues from comparative transcriptomics in Saccharomyces cerevisiae and Candida glabrata. Genome Biol (2008) 1.02
Real-time assays for the assembly-disassembly cycle of COP coats on liposomes of defined size. Methods Enzymol (2005) 1.01
Extension of a local backbone description using a structural alphabet: a new approach to the sequence-structure relationship. Protein Sci (2002) 0.99
Local backbone structure prediction of proteins. In Silico Biol (2004) 0.98
Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat. Mol Biol Cell (2008) 0.97
The long and short of membrane fission. Cell (2008) 0.97
Interpretation of 2H-NMR experiments on the orientation of the transmembrane helix WALP23 by computer simulations. Biophys J (2010) 0.95
Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel. Structure (2010) 0.95
PredyFlexy: flexibility and local structure prediction from sequence. Nucleic Acids Res (2012) 0.94
Theoretical model of human apolipoprotein B100 tertiary structure. Proteins (2007) 0.91
Cell biology. Vitamin currency in a lipid exchange market. Science (2013) 0.90
Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits. Biochemistry (2005) 0.89
Structural model of the anion exchanger 1 (SLC4A1) and identification of transmembrane segments forming the transport site. J Biol Chem (2013) 0.88
Membrane bending: the power of protein imbalance. Trends Biochem Sci (2013) 0.88
Insights into the mechanisms of sterol transport between organelles. Cell Mol Life Sci (2013) 0.88
Assessing a novel approach for predicting local 3D protein structures from sequence. Proteins (2006) 0.88
Predicting protein flexibility through the prediction of local structures. Proteins (2010) 0.87
Taking advantage of local structure descriptors to analyze interresidue contacts in protein structures and protein complexes. Proteins (2008) 0.86
A novel membrane sensor controls the localization and ArfGEF activity of bacterial RalF. PLoS Pathog (2013) 0.86
A new prediction strategy for long local protein structures using an original description. Proteins (2009) 0.85
Amphipathic-Lipid-Packing-Sensor interactions with lipids assessed by atomistic molecular dynamics. Biochim Biophys Acta (2011) 0.84
New insights of membrane environment effects on MscL channel mechanics from theoretical approaches. Proteins (2008) 0.84
Arf GTPase regulation through cascade mechanisms and positive feedback loops. FEBS Lett (2013) 0.84
Cell biology: Detached membrane bending. Nature (2009) 0.84
Modeling and molecular dynamics of HPA-1a and -1b polymorphisms: effects on the structure of the β3 subunit of the αIIbβ3 integrin. PLoS One (2012) 0.83
Arf1 and membrane curvature cooperate to recruit Arfaptin2 to liposomes. PLoS One (2013) 0.82
Mg2+ in the major groove modulates B-DNA structure and dynamics. PLoS One (2012) 0.82
Clustering of protein domains for functional and evolutionary studies. BMC Bioinformatics (2009) 0.81
Studying in vitro membrane curvature recognition by proteins and its role in vesicular trafficking. Methods Cell Biol (2012) 0.81
Methyl-branched lipids promote the membrane adsorption of α-synuclein by enhancing shallow lipid-packing defects. Phys Chem Chem Phys (2015) 0.81
Aminopeptidase B, a glucagon-processing enzyme: site directed mutagenesis of the Zn2+-binding motif and molecular modelling. BMC Biochem (2007) 0.81
Nonlinear active materials: an illustration of controllable phase matchability. J Am Chem Soc (2013) 0.80
In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors. Methods Enzymol (2008) 0.79
Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory. J Membr Biol (2015) 0.79
Cell biology: helices sculpt membrane. Nature (2005) 0.78
The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins. PLoS One (2011) 0.78
Decoding the structural events in substrate-gating mechanism of eukaryotic prolyl oligopeptidase using normal mode analysis and molecular dynamics simulations. Proteins (2014) 0.78
The role of polar, lamdba (Λ)-shaped building units in noncentrosymmetric inorganic structures. J Am Chem Soc (2012) 0.78
In silico studies on DARC. Infect Disord Drug Targets (2009) 0.78
A procedure for refining a coiled coil protein structure using x-ray fiber diffraction and modeling. Biophys J (2002) 0.78
Influence of assignment on the prediction of transmembrane helices in protein structures. Amino Acids (2010) 0.78
Insights on pH-dependent conformational changes of mosquito odorant binding proteins by molecular dynamics simulations. J Biomol Struct Dyn (2013) 0.77
Liposomes in the study of GDP/GTP cycle of Arf and related small G proteins. Methods Enzymol (2003) 0.77
Syntheses of two vanadium oxide-fluoride materials that differ in phase matchability. Inorg Chem (2014) 0.75
Mutation in the substrate-binding site of aminopeptidase B confers new enzymatic properties. Biochimie (2011) 0.75
Directing traffic into the future. Dev Cell (2013) 0.75
GEF and glucosylation assays on liposome-bound Rac. Methods Enzymol (2006) 0.75
[Regulation of vesicular transport by membrane curvature]. Med Sci (Paris) (2009) 0.75
From solution to the solid state: control of niobium oxide-fluoride [NbOxFy]n- species. Inorg Chem (2013) 0.75