Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 23443569)

Published in Nat Commun on January 01, 2013

Authors

Barbara Mosca1, Osvaldo Delbono, Maria Laura Messi, Leda Bergamelli, Zhong-Min Wang, Mirko Vukcevic, Ruben Lopez, Susan Treves, Miyuki Nishi, Hiroshi Takeshima, Cecilia Paolini, Marta Martini, Giorgio Rispoli, Feliciano Protasi, Francesco Zorzato

Author Affiliations

1: Department of Experimental and Diagnostic Medicine, General Pathology section, University of Ferrara, Via Borsari 46, Ferrara 44121, Italy.

Articles citing this

Differential effects of RGK proteins on L-type channel function in adult mouse skeletal muscle. Biophys J (2014) 0.89

RGK protein-mediated impairment of slow depolarization- dependent Ca2+ entry into developing myotubes. Channels (Austin) (2014) 0.88

Essential role of the zinc finger transcription factor Casz1 for mammalian cardiac morphogenesis and development. J Biol Chem (2014) 0.87

The couplonopathies: A comparative approach to a class of diseases of skeletal and cardiac muscle. J Gen Physiol (2015) 0.86

The power of the mind: the cortex as a critical determinant of muscle strength/weakness. J Neurophysiol (2014) 0.83

Distinct Components of Retrograde CaV1.1-RyR1 Coupling Revealed by a Lethal Mutation in RyR1. Biophys J (2016) 0.82

Voltage-gated Ca(2+) influx through L-type channels contributes to sarcoplasmic reticulum Ca(2+) loading in skeletal muscle. J Physiol (2015) 0.79

Alternating bipolar field stimulation identifies muscle fibers with defective excitability but maintained local Ca(2+) signals and contraction. Skelet Muscle (2016) 0.76

Identification of differentially expressed genes in breast muscle and skin fat of postnatal Pekin duck. PLoS One (2014) 0.75

Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles. J Biol Chem (2016) 0.75

Retrograde regulation of STIM1-Orai1 interaction and store-operated Ca2+ entry by calsequestrin. Sci Rep (2015) 0.75

Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Skelet Muscle (2016) 0.75

The excitation-contraction coupling mechanism in skeletal muscle. Biophys Rev (2014) 0.75

A new look at structures and mechanisms regulating endoplasmic/sarcoplasmic reticulum Ca(2+) release in health and disease. J Physiol (2015) 0.75

Articles cited by this

Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA. Nature (1988) 5.73

The role of Ca2+ ions in excitation-contraction coupling of skeletal muscle fibres. Biochim Biophys Acta (1995) 4.67

Voltage sensor of excitation-contraction coupling in skeletal muscle. Physiol Rev (1991) 4.66

Twitches in the presence of ethylene glycol bis( -aminoethyl ether)-N,N'-tetracetic acid. Biochim Biophys Acta (1972) 4.63

Enhanced dihydropyridine receptor channel activity in the presence of ryanodine receptor. Nature (1996) 4.42

Sizes of components in frog skeletal muscle measured by methods of stereology. J Gen Physiol (1975) 3.76

Structure and development of E-C coupling units in skeletal muscle. Annu Rev Physiol (1994) 3.28

QUANTITATIVE EVALUATION OF CYTOPLASMIC STRUCTURES IN ELECTRON MICROGRAPHS. Lab Invest (1965) 2.98

[3H]nitrendipine receptors in skeletal muscle. J Biol Chem (1983) 2.77

Skeletal muscle weakness in old age: underlying mechanisms. Med Sci Sports Exerc (1994) 2.22

Dynapenia and aging: an update. J Gerontol A Biol Sci Med Sci (2011) 2.19

Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging. Cell Metab (2011) 2.06

Dysfunction of store-operated calcium channel in muscle cells lacking mg29. Nat Cell Biol (2002) 2.03

Depletion of Ca2+ in the sarcoplasmic reticulum stimulates Ca2+ entry into mouse skeletal muscle fibres. J Physiol (2001) 1.97

Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells. J Biol Chem (1992) 1.80

Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1. J Physiol (2007) 1.78

The cell boundary theorem: a simple law of the control of cytosolic calcium concentration. J Physiol Sci (2009) 1.73

Store-operated Ca2+ entry during intracellular Ca2+ release in mammalian skeletal muscle. J Physiol (2007) 1.62

Muscle wasting in cancer cachexia: clinical implications, diagnosis, and emerging treatment strategies. Annu Rev Med (2011) 1.57

Slow inward calcium currents have no obvious role in muscle excitation-contraction coupling. Nature (1982) 1.56

Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene. Mol Pharmacol (2008) 1.55

Patch-clamp recording of charge movement, Ca2+ current, and Ca2+ transients in adult skeletal muscle fibers. Biophys J (1999) 1.51

The skeletal L-type Ca(2+) current is a major contributor to excitation-coupled Ca(2+) entry. J Gen Physiol (2009) 1.50

Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes. Biophys J (2006) 1.48

Azumolene inhibits a component of store-operated calcium entry coupled to the skeletal muscle ryanodine receptor. J Biol Chem (2006) 1.46

Role of calcium permeation in dihydropyridine receptor function. Insights into channel gating and excitation-contraction coupling. J Gen Physiol (1999) 1.43

Asymmetric charge movement in contracting muscle fibres in the rabbit. J Physiol (1986) 1.42

Impaired calcium release during fatigue. J Appl Physiol (1985) (2007) 1.28

High-affinity [3H]PN200-110 and [3H]ryanodine binding to rabbit and frog skeletal muscle. Am J Physiol (1994) 1.20

Extracellular ions and excitation-contraction coupling in frog twitch muscle fibres. J Physiol (1984) 1.13

Myosin heavy chain isoform composition and Ca(2+) transients in fibres from enzymatically dissociated murine soleus and extensor digitorum longus muscles. J Physiol (2009) 1.13

A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle. Biophys J (2009) 1.12

Massive alterations of sarcoplasmic reticulum free calcium in skeletal muscle fibers lacking calsequestrin revealed by a genetically encoded probe. Proc Natl Acad Sci U S A (2010) 1.12

Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca(2+) release in skeletal muscle. J Gen Physiol (2011) 1.09

Sarcoplasmic reticulum Ca2+ release and depletion fail to affect sarcolemmal ion channel activity in mouse skeletal muscle. J Physiol (2006) 1.05

Minor sarcoplasmic reticulum membrane components that modulate excitation-contraction coupling in striated muscles. J Physiol (2009) 1.01

The role of calcium stores in fatigue of isolated single muscle fibres from the cane toad. J Physiol (1999) 0.99

Excitation contraction coupling in skeletal muscle: evidence for a role of slow Ca2+ channels using Ca2+ channel activators and inhibitors in the dihydropyridine series. Biochem Biophys Res Commun (1985) 0.98

Low-affinity Ca2+ indicators compared in measurements of skeletal muscle Ca2+ transients. Biophys J (2009) 0.97

Loss of skeletal muscle strength by ablation of the sarcoplasmic reticulum protein JP45. Proc Natl Acad Sci U S A (2007) 0.97

Calsequestrin (CASQ1) rescues function and structure of calcium release units in skeletal muscles of CASQ1-null mice. Am J Physiol Cell Physiol (2011) 0.96

Mice null for calsequestrin 1 exhibit deficits in functional performance and sarcoplasmic reticulum calcium handling. PLoS One (2011) 0.89

Ryanodine receptor activation by Ca v 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression. J Biol Chem (2008) 0.89

The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1. J Cell Sci (2006) 0.89

Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes. Biophys J (2012) 0.88

Endogenously determined restriction of food intake overcomes excitation-contraction uncoupling in JP45KO mice with aging. Exp Gerontol (2012) 0.82

Voltage clamp methods for the study of membrane currents and SR Ca(2+) release in adult skeletal muscle fibres. Prog Biophys Mol Biol (2012) 0.78

Articles by these authors

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab (2008) 4.91

RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice. Cell (2008) 3.27

MG53 nucleates assembly of cell membrane repair machinery. Nat Cell Biol (2008) 3.24

TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat Med (2008) 2.77

MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation (2010) 2.35

Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell Metab (2008) 2.34

Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Sci Transl Med (2012) 2.27

Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin. J Biol Chem (2009) 2.25

Dysfunction of store-operated calcium channel in muscle cells lacking mg29. Nat Cell Biol (2002) 2.03

The contribution of reactive oxygen species to sarcopenia and muscle ageing. Exp Gerontol (2004) 1.98

Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44. EMBO J (2003) 1.96

Anesthetic- and heat-induced sudden death in calsequestrin-1-knockout mice. FASEB J (2009) 1.88

Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev (2002) 1.83

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion. J Cell Biol (2004) 1.80

Mitochondria are linked to calcium stores in striated muscle by developmentally regulated tethering structures. Mol Biol Cell (2008) 1.80

Reorganized stores and impaired calcium handling in skeletal muscle of mice lacking calsequestrin-1. J Physiol (2007) 1.78

Cardioprotection of ischemia/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair. Circ Res (2010) 1.74

A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. Am J Respir Crit Care Med (2012) 1.74

Concentration gradient patterns of aerosol particles near interstate highways in the Greater Cincinnati airshed. J Environ Monit (2003) 1.70

Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun (2004) 1.69

Efficacy assessment of meloxicam, a preferential cyclooxygenase-2 inhibitor, in acute coronary syndromes without ST-segment elevation: the Nonsteroidal Anti-Inflammatory Drugs in Unstable Angina Treatment-2 (NUT-2) pilot study. Circulation (2002) 1.69

Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model. Circ Res (2008) 1.67

Muscle aging is associated with compromised Ca2+ spark signaling and segregated intracellular Ca2+ release. J Cell Biol (2006) 1.64

MG53 regulates membrane budding and exocytosis in muscle cells. J Biol Chem (2008) 1.60

Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. J Neurosci (2003) 1.59

TRIC channels are essential for Ca2+ handling in intracellular stores. Nature (2007) 1.58

Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice. Circulation (2011) 1.57

Functional properties of RYR1 mutations identified in Swedish patients with malignant hyperthermia and central core disease. Anesth Analg (2010) 1.55

Ryanodine receptor 1 mutations, dysregulation of calcium homeostasis and neuromuscular disorders. Neuromuscul Disord (2005) 1.54

The assembly of calcium release units in cardiac muscle. Ann N Y Acad Sci (2005) 1.53

Insulin-like growth factor-1 prevents age-related decrease in specific force and intracellular Ca2+ in single intact muscle fibres from transgenic mice. J Physiol (2003) 1.53

Molecular mechanisms and phenotypic variation in RYR1-related congenital myopathies. Brain (2007) 1.52

Uncoupling store-operated Ca2+ entry and altered Ca2+ release from sarcoplasmic reticulum through silencing of junctophilin genes. Biophys J (2006) 1.48

Crucial roles of Brn1 in distal tubule formation and function in mouse kidney. Development (2003) 1.44

Activation of endoplasmic reticulum stress response by hepatitis viruses up-regulates protein phosphatase 2A. Hepatology (2007) 1.44

Effect of eplerenone on endothelial progenitor cells and oxidative stress in ischemic hindlimb. Am J Hypertens (2010) 1.43

Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis. EMBO J (2007) 1.43

Enhanced resistance to fatigue and altered calcium handling properties of sarcalumenin knockout mice. Physiol Genomics (2005) 1.43

Mutation of junctophilin type 2 associated with hypertrophic cardiomyopathy. J Hum Genet (2007) 1.40

Long-term high-level exercise promotes muscle reinnervation with age. J Neuropathol Exp Neurol (2014) 1.40

Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair. J Biol Chem (2011) 1.40

The relative position of RyR feet and DHPR tetrads in skeletal muscle. J Mol Biol (2004) 1.39

Essential immunoregulatory role for BCAP in B cell development and function. J Exp Med (2002) 1.36

Long-term denervation in humans causes degeneration of both contractile and excitation-contraction coupling apparatus, which is reversible by functional electrical stimulation (FES): a role for myofiber regeneration? J Neuropathol Exp Neurol (2004) 1.36

Congenital muscle disorders with cores: the ryanodine receptor calcium channel paradigm. Curr Opin Pharmacol (2008) 1.34

Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease. FASEB J (2011) 1.33

Differential contribution of skeletal and cardiac II-III loop sequences to the assembly of dihydropyridine-receptor arrays in skeletal muscle. Mol Biol Cell (2004) 1.29

Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family. FEBS Lett (2006) 1.28

Centronuclear myopathy due to a de novo dominant mutation in the skeletal muscle ryanodine receptor (RYR1) gene. Neuromuscul Disord (2007) 1.28

Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem (2007) 1.25

Immuno-proteomic approach to excitation--contraction coupling in skeletal and cardiac muscle: molecular insights revealed by the mitsugumins. Cell Calcium (2007) 1.24

Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle. Biophys J (2002) 1.23

Characterization and temporal development of cores in a mouse model of malignant hyperthermia. Proc Natl Acad Sci U S A (2009) 1.22

Sarcoplasmic reticulum Ca2+ release declines in muscle fibers from aging mice. Biophys J (2008) 1.22

Calsequestrin-1: a new candidate gene for malignant hyperthermia and exertional/environmental heat stroke. J Physiol (2009) 1.21

Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments. Proc Natl Acad Sci U S A (2011) 1.20

Atrophy/hypertrophy cell signaling in muscles of young athletes trained with vibrational-proprioceptive stimulation. Neurol Res (2011) 1.19

Structural differentiation of skeletal muscle fibers in the absence of innervation in humans. Proc Natl Acad Sci U S A (2007) 1.19

Ectosomes released by polymorphonuclear neutrophils induce a MerTK-dependent anti-inflammatory pathway in macrophages. J Biol Chem (2010) 1.19

Progressive disorganization of the excitation-contraction coupling apparatus in aging human skeletal muscle as revealed by electron microscopy: a possible role in the decline of muscle performance. J Gerontol A Biol Sci Med Sci (2006) 1.19

Ero1α regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM). Antioxid Redox Signal (2011) 1.17

Home-based functional electrical stimulation rescues permanently denervated muscles in paraplegic patients with complete lower motor neuron lesion. Neurorehabil Neural Repair (2010) 1.17

Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair. FASEB J (2012) 1.16

Genome drafts of four phytoplasma strains of the ribosomal group 16SrIII. Microbiology (2012) 1.13

Characterization of recessive RYR1 mutations in core myopathies. Hum Mol Genet (2006) 1.12

Coexpression of junctophilin type 3 and type 4 in brain. Brain Res Mol Brain Res (2003) 1.11

Skeletal muscle pericyte subtypes differ in their differentiation potential. Stem Cell Res (2012) 1.09

Effect of ryanodine receptor mutations on interleukin-6 release and intracellular calcium homeostasis in human myotubes from malignant hyperthermia-susceptible individuals and patients affected by central core disease. J Biol Chem (2004) 1.09

Deficiency of triad formation in developing skeletal muscle cells lacking junctophilin type 1. FEBS Lett (2002) 1.09

Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair. Commun Integr Biol (2009) 1.08

Sarcoplasmic reticulum Ca2+ depletion in adult skeletal muscle fibres measured with the biosensor D1ER. Pflugers Arch (2010) 1.08

Ryanodine receptor type 2 deficiency changes excitation-contraction coupling and membrane potential in urinary bladder smooth muscle. J Physiol (2007) 1.06

External Ca(2+)-dependent excitation--contraction coupling in a population of ageing mouse skeletal muscle fibres. J Physiol (2004) 1.06

Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice. J Biol Chem (2004) 1.05

Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilins. Proc Natl Acad Sci U S A (2006) 1.05

Age-dependent imbalance of the antioxidative system in human satellite cells. Exp Gerontol (2004) 1.05

Remodeling of calcium handling in skeletal muscle through PGC-1α: impact on force, fatigability, and fiber type. Am J Physiol Cell Physiol (2011) 1.05

Neurogenesis of excitation-contraction uncoupling in aging skeletal muscle. Exerc Sport Sci Rev (2004) 1.04

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease. EMBO Mol Med (2013) 1.04

Increasing the number of diagnostic mutations in malignant hyperthermia. Hum Mutat (2009) 1.04