Published in Drug Saf on January 01, 2012
Proton pump inhibitors and risk of 1-year mortality and rehospitalization in older patients discharged from acute care hospitals. JAMA Intern Med (2013) 3.08
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. Exp Gerontol (2005) 3.06
Drawing impairment predicts mortality in severe COPD. Chest (2006) 2.45
Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. J Clin Endocrinol Metab (2003) 2.40
Recommendations to prescribe in complex older adults: results of the CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project. Drugs Aging (2014) 2.03
Weight loss in combination with physical activity improves endothelial dysfunction in human obesity. Diabetes Care (2003) 1.72
Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev (2005) 1.49
An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease. J Alzheimers Dis (2011) 1.45
Metabolic syndrome and health-related quality of life: does psychological well-being matter? Ann Epidemiol (2008) 1.40
Comorbidities of chronic obstructive pulmonary disease. Curr Opin Pulm Med (2011) 1.23
Comorbidity and social factors predicted hospitalization in frail elderly patients. J Clin Epidemiol (2004) 1.20
Moving against frailty: does physical activity matter? Biogerontology (2010) 1.19
Prevalence and risk factors for falls in an older community-dwelling population. J Gerontol A Biol Sci Med Sci (2002) 1.13
Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patients. J Am Coll Nutr (2006) 1.12
Chronic renal failure: a neglected comorbidity of COPD. Chest (2009) 1.12
Potentially inappropriate drug prescriptions and risk of hospitalization among older, Italian, nursing home residents: the ULISSE project. Drugs Aging (2010) 1.11
Numerical and functional alterations of circulating gammadelta T lymphocytes in aged people and centenarians. J Leukoc Biol (2002) 1.11
From chronic low back pain to disability, a multifactorial mediated pathway: the InCHIANTI study. Spine (Phila Pa 1976) (2007) 1.10
Leukocyte telomere shortening in elderly Type2DM patients with previous myocardial infarction. Atherosclerosis (2009) 1.09
Physical activity and mortality in frail, community-living elderly patients. J Gerontol A Biol Sci Med Sci (2004) 1.09
Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease. PLoS One (2010) 1.06
The economic burden of inappropriate drug prescribing, lack of adherence and compliance, adverse drug events in older people: a systematic review. Drug Saf (2012) 1.05
Global DNA methylation in old subjects is correlated with frailty. Age (Dordr) (2011) 1.05
Adverse drug events as a cause of hospitalization in older adults. Drug Saf (2012) 1.05
The G/C915 polymorphism of transforming growth factor beta1 is associated with human longevity: a study in Italian centenarians. Aging Cell (2004) 1.04
Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity. Exp Gerontol (2004) 1.03
Metformin-induced pancreatitis: A possible adverse drug effect during acute renal failure. Diabetes Care (2006) 1.03
Construct validity of the Short Form-36 Health Survey and its relationship with BMI in obese outpatients. Obesity (Silver Spring) (2006) 1.02
Underprescription of beneficial medicines in older people: causes, consequences and prevention. Drugs Aging (2012) 1.02
Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis. Exp Gerontol (2004) 1.01
Reduced number and impaired function of circulating gamma delta T cells in patients with cutaneous primary melanoma. J Invest Dermatol (2003) 1.01
Polypharmacy in elderly patients at discharge from the acute care hospital. Ther Clin Risk Manag (2007) 0.99
Polypharmacy and health outcomes among older adults discharged from hospital: results from the CRIME study. Geriatr Gerontol Int (2014) 0.98
Rosiglitazone and cognitive stability in older individuals with type 2 diabetes and mild cognitive impairment. Diabetes Care (2010) 0.98
Comparative efficacies of quinupristin-dalfopristin, linezolid, vancomycin, and ciprofloxacin in treatment, using the antibiotic-lock technique, of experimental catheter-related infection due to Staphylococcus aureus. Antimicrob Agents Chemother (2005) 0.98
Potentially inappropriate medication in elderly hospitalized patients. Drugs Aging (2009) 0.97
Effects of donepezil, galantamine and rivastigmine in 938 Italian patients with Alzheimer's disease: a prospective, observational study. CNS Drugs (2010) 0.97
Indwelling urethral catheter and mortality in frail elderly women living in community. Neurourol Urodyn (2004) 0.97
Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects. J Nutr Biochem (2009) 0.97
Regimen complexity and medication nonadherence in elderly patients. Ther Clin Risk Manag (2009) 0.96
Potentially inappropriate medications and functional decline in elderly hospitalized patients. J Am Geriatr Soc (2009) 0.95
Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD). Curr Neuropharmacol (2008) 0.95
Predictors of hospitalization in Italian nursing home residents: the U.L.I.S.S.E. project. J Am Med Dir Assoc (2011) 0.95
PON1 is a longevity gene: results of a meta-analysis. Ageing Res Rev (2009) 0.94
Inflammation, chronic obstructive pulmonary disease and aging. Curr Opin Pulm Med (2011) 0.94
Prognostic significance of the short physical performance battery in older patients discharged from acute care hospitals. Rejuvenation Res (2011) 0.93
Screening of cognitive impairment in chronic obstructive pulmonary disease. Dement Geriatr Cogn Disord (2007) 0.92
Prognostic stratification of elderly patients in the emergency department: a comparison between the "Identification of Seniors at Risk" and the "Silver Code". J Gerontol A Biol Sci Med Sci (2011) 0.92
The -174 C/G locus affects in vitro/in vivo IL-6 production during aging. Exp Gerontol (2002) 0.92
The role of IL-1 gene cluster in longevity: a study in Italian population. Mech Ageing Dev (2003) 0.92
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians. Eur J Hum Genet (2002) 0.91
Potentially reversible risk factors and urinary incontinence in frail older people living in community. Age Ageing (2003) 0.91
Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics. Exp Gerontol (2007) 0.91
Targeting inflammation to slow or delay functional decline: where are we? Biogerontology (2010) 0.89
Treatment of severe pulmonary hypertension secondary to scleroderma: a three-drug approach. Intern Med (2008) 0.89
A polymorphism of the YTHDF2 gene (1p35) located in an Alu-rich genomic domain is associated with human longevity. J Gerontol A Biol Sci Med Sci (2006) 0.89
Tigecycline accelerates staphylococcal-infected burn wound healing through matrix metalloproteinase-9 modulation. J Antimicrob Chemother (2011) 0.89
A novel, population-specific approach to define frailty. Age (Dordr) (2010) 0.89
Estimating renal function in older people: a comparison of three formulas. Age Ageing (2006) 0.88
Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers. Coron Artery Dis (2005) 0.88
Plasma copper/zinc ratio: an inflammatory/nutritional biomarker as predictor of all-cause mortality in elderly population. Biogerontology (2009) 0.88
Underrecognition and undertreatment of dementia in Italian nursing homes. J Am Med Dir Assoc (2012) 0.88
The economic burden of chronic obstructive pulmonary disease in the elderly: results from a systematic review of the literature. Curr Opin Pulm Med (2011) 0.87
RNA-mediated gene silencing of nicotinamide N-methyltransferase is associated with decreased tumorigenicity in human oral carcinoma cells. PLoS One (2013) 0.87
Construct validity of activities of daily living scale: a clue to distinguish the disabling effects of COPD and congestive heart failure. Chest (2005) 0.86
Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice. Carcinogenesis (2013) 0.86
Phenotype, antigen-presenting capacity, and migration of antigen-presenting cells in young and old age. Exp Gerontol (2002) 0.86
Chronic kidney disease and 1-year survival in elderly patients discharged from acute care hospitals: a comparison of three glomerular filtration rate equations. Nephrol Dial Transplant (2010) 0.86
Quorum sensing inhibitor FS3-coated vascular graft enhances daptomycin efficacy in a rat model of staphylococcal infection. Peptides (2012) 0.86
Genetic polymorphisms of inflammatory cytokines and myocardial infarction in the elderly. Mech Ageing Dev (2006) 0.86
Risk stratification of older patients in the emergency department: comparison between the Identification of Seniors at Risk and Triage Risk Screening Tool. Rejuvenation Res (2012) 0.86
Relationship between renal function and physical performance in elderly hospitalized patients. Rejuvenation Res (2012) 0.85
Relationship between renal function and functional decline: role of the estimating equation. J Am Med Dir Assoc (2011) 0.85
A genetic-demographic approach reveals male-specific association between survival and tumor necrosis factor (A/G)-308 polymorphism. J Gerontol A Biol Sci Med Sci (2008) 0.85
Opioids for the treatment of chronic non-cancer pain in older people. Drugs Aging (2009) 0.85
The interleukin-6 -174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients. Int J Cardiol (2005) 0.85
Correlation between cognitive impairment and dependence in hypoxemic COPD. J Clin Exp Neuropsychol (2008) 0.85
Depression, hypertension, and comorbidity: disentangling their specific effect on disability and cognitive impairment in older subjects. Arch Gerontol Geriatr (2010) 0.85
From Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines to current clinical practice : an overview of the pharmacological therapy of stable chronic obstructive pulmonary disorder. Drugs Aging (2006) 0.85
Reliability of equations to estimate glomerular filtration rate in the very old. Aging Clin Exp Res (2008) 0.85
Remodelling of biological parameters during human ageing: evidence for complex regulation in longevity and in type 2 diabetes. Age (Dordr) (2011) 0.85
Socioeconomic status and hospitalization in the very old: a retrospective study. BMC Public Health (2007) 0.85
Prevalence and potentially reversible factors associated with anorexia among older nursing home residents: results from the ULISSE project. J Am Med Dir Assoc (2012) 0.84
Age- and gender-related alterations of the number and clonogenic capacity of circulating CD34+ progenitor cells. Biogerontology (2005) 0.84
Association between glomerular filtration rate and adverse drug reactions in elderly hospitalized patients: the role of the estimating equation. Drugs Aging (2011) 0.84
Geriatric conditions and the risk of adverse drug reactions in older adults: a review. Drug Saf (2012) 0.84
The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: study protocol for a randomized controlled trial. Trials (2013) 0.84