Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infection.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 3585811)

Published in PLoS One on March 01, 2013

Authors

Olivier Leymarie1, Grégory Jouvion, Pierre-Louis Hervé, Christophe Chevalier, Valérie Lorin, Jérôme Lecardonnel, Bruno Da Costa, Bernard Delmas, Nicolas Escriou, Ronan Le Goffic

Author Affiliations

1: Unité de Virologie et Immunologie Moléculaires, UR 892 INRA, Domaine de Vilvert, Jouy-en-Josas, France.

Articles cited by this

Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol (2001) 21.17

Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science (2001) 18.43

A DNA transfection system for generation of influenza A virus from eight plasmids. Proc Natl Acad Sci U S A (2000) 12.16

A novel influenza A virus mitochondrial protein that induces cell death. Nat Med (2001) 9.90

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat Med (2002) 9.47

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature (2006) 6.46

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature (2004) 6.11

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature (1999) 5.76

Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host Microbe (2007) 5.46

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS Pathog (2007) 4.99

Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc Natl Acad Sci U S A (2001) 4.93

Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice. J Virol (2006) 4.74

Preparing for the next pandemic. N Engl J Med (2005) 4.65

Eight-plasmid system for rapid generation of influenza virus vaccines. Vaccine (2002) 4.45

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat Med (2009) 4.22

HMGB1: endogenous danger signaling. Mol Med (2008) 4.02

Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog (2005) 3.44

The NS1 gene contributes to the virulence of H5N1 avian influenza viruses. J Virol (2006) 3.03

A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA. J Virol (2009) 2.94

The influenza A virus PB1-F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function. J Virol (2003) 2.76

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proc Natl Acad Sci U S A (2008) 2.72

Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. J Virol (2004) 2.67

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes. PLoS Pathog (2009) 2.44

PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes. J Virol (2004) 2.12

PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal models. J Virol (2010) 2.01

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cell Microbiol (2008) 1.90

Innate immune responses to influenza A H5N1: friend or foe? Trends Immunol (2009) 1.89

Prevalence of PB1-F2 of influenza A viruses. J Gen Virol (2007) 1.88

PB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology. PLoS Pathog (2010) 1.75

Avian influenza viruses in humans. Rev Sci Tech (2009) 1.73

The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis. J Virol (2010) 1.63

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein. PLoS Pathog (2011) 1.60

High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1. Mol Biol Cell (2011) 1.55

Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem (2005) 1.52

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species. PLoS Pathog (2011) 1.49

Pandemic influenza as a current threat. Curr Top Microbiol Immunol (2009) 1.49

A single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivo. J Virol (2010) 1.44

Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells. J Immunol (2010) 1.38

Influenza virus protein PB1-F2 inhibits the induction of type I interferon by binding to MAVS and decreasing mitochondrial membrane potential. J Virol (2012) 1.29

The PB1-F2 protein of Influenza A virus: increasing pathogenicity by disrupting alveolar macrophages. Virol J (2007) 1.24

Impact of amino acid mutations in PB2, PB1-F2, and NS1 on the replication and pathogenicity of pandemic (H1N1) 2009 influenza viruses. J Virol (2011) 1.17

Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein. PLoS Pathog (2011) 1.12

The influenza virus PB1-F2 protein has interferon antagonistic activity. Biol Chem (2011) 1.08

PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments. J Biol Chem (2010) 1.04

Three amino acid changes in PB1-F2 of highly pathogenic H5N1 avian influenza virus affect pathogenicity in mallard ducks. Arch Virol (2010) 1.02

The RON receptor tyrosine kinase regulates IFN-gamma production and responses in innate immunity. J Immunol (2008) 1.01

The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel. PLoS One (2010) 0.96

Restored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine. J Virol (2012) 0.94

The influenza A virus protein PB1-F2: killing two birds with one stone? Virulence (2011) 0.90

Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines. Funct Integr Genomics (2011) 0.89

PB1-F2 modulates early host responses but does not affect the pathogenesis of H1N1 seasonal influenza virus. J Virol (2012) 0.89

Evasion of natural killer cells by influenza virus. J Leukoc Biol (2010) 0.83

Articles by these authors

Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med (2003) 27.97

Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet (2003) 6.52

Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem (2004) 3.88

Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia. PLoS Pathog (2006) 3.04

The birnavirus crystal structure reveals structural relationships among icosahedral viruses. Cell (2005) 2.44

Antigen crosspresentation by human plasmacytoid dendritic cells. Immunity (2007) 2.42

Codon conservation in the influenza A virus genome defines RNA packaging signals. Nucleic Acids Res (2007) 2.24

The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment. Virology (2005) 1.55

Chondrocytes play a major role in the stimulation of bone growth by thyroid hormone. Endocrinology (2014) 1.41

Influenza A virus protein PB1-F2 exacerbates IFN-beta expression of human respiratory epithelial cells. J Immunol (2010) 1.38

Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus. J Bacteriol (2009) 1.36

Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood (2008) 1.32

The capsid of infectious bursal disease virus contains several small peptides arising from the maturation process of pVP2. J Virol (2002) 1.32

Infection with influenza virus induces IL-33 in murine lungs. Am J Respir Cell Mol Biol (2011) 1.29

Annexin II incorporated into influenza virus particles supports virus replication by converting plasminogen into plasmin. J Virol (2008) 1.23

Epidemiology, molecular virology and diagnostics of Schmallenberg virus, an emerging orthobunyavirus in Europe. Vet Res (2013) 1.20

Biochemical characterization of the respiratory syncytial virus P-P and P-N protein complexes and localization of the P protein oligomerization domain. J Gen Virol (2004) 1.18

Murine plasmacytoid dendritic cells induce effector/memory CD8+ T-cell responses in vivo after viral stimulation. Blood (2004) 1.17

Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J Gen Virol (2005) 1.16

The maturation process of pVP2 requires assembly of infectious bursal disease virus capsids. J Virol (2002) 1.16

Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax. Am J Pathol (2011) 1.16

Bioluminescent Aspergillus fumigatus, a new tool for drug efficiency testing and in vivo monitoring of invasive aspergillosis. Appl Environ Microbiol (2008) 1.16

Crystal structure of a novel viral protease with a serine/lysine catalytic dyad mechanism. J Mol Biol (2006) 1.14

HLA-B*0702 transgenic, H-2KbDb double-knockout mice: phenotypical and functional characterization in response to influenza virus. Int Immunol (2003) 1.13

Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein. PLoS Pathog (2011) 1.12

The picobirnavirus crystal structure provides functional insights into virion assembly and cell entry. EMBO J (2009) 1.10

Introduction of SARS in France, March-April, 2003. Emerg Infect Dis (2004) 1.10

Monomeric nucleoprotein of influenza A virus. PLoS Pathog (2013) 1.07

In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis. BMC Microbiol (2010) 1.07

Molecular and structural bases for the antigenicity of VP2 of infectious bursal disease virus. J Virol (2007) 1.04

PB1-F2 influenza A virus protein adopts a beta-sheet conformation and forms amyloid fibers in membrane environments. J Biol Chem (2010) 1.04

Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice. Gastroenterology (2010) 1.04

Avian adenovirus CELO recombinants expressing VP2 of infectious bursal disease virus induce protection against bursal disease in chickens. Vaccine (2004) 1.02

Tissue tropism and target cells of NSs-deleted rift valley fever virus in live immunodeficient mice. PLoS Negl Trop Dis (2011) 1.00

Blotched snakehead virus is a new aquatic birnavirus that is slightly more related to avibirnavirus than to aquabirnavirus. J Virol (2003) 1.00

Aedes mosquito saliva modulates Rift Valley fever virus pathogenicity. PLoS Negl Trop Dis (2013) 1.00

Infectious bursal disease virus, a non-enveloped virus, possesses a capsid-associated peptide that deforms and perforates biological membranes. J Biol Chem (2007) 0.99

Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus. Antivir Ther (2007) 0.99

Anaeroglobus geminatus gen. nov., sp. nov., a novel member of the family Veillonellaceae. Int J Syst Evol Microbiol (2002) 0.98

Molecular characterization of a Streptococcus gallolyticus genomic island encoding a pilus involved in endocarditis. J Infect Dis (2011) 0.98

Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters. PLoS Negl Trop Dis (2010) 0.97

Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus. Antimicrob Agents Chemother (2013) 0.96

Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages. PLoS Pathog (2007) 0.96

Identification of one novel candidate probiotic Lactobacillus plantarum strain active against influenza virus infection in mice by a large-scale screening. Appl Environ Microbiol (2012) 0.95

Expression of a foreign gene by stable recombinant influenza viruses harboring a dicistronic genomic segment with an internal promoter. Virology (2003) 0.94

Anti-severe acute respiratory syndrome coronavirus spike antibodies trigger infection of human immune cells via a pH- and cysteine protease-independent FcγR pathway. J Virol (2011) 0.93

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity. PLoS Pathog (2013) 0.93

TLR 5, but neither TLR2 nor TLR4, is involved in lung epithelial cell response to Burkholderia cenocepacia. FEMS Immunol Med Microbiol (2008) 0.92

Recombinant influenza A viruses harboring optimized dicistronic NA segment with an extended native 5' terminal sequence: induction of heterospecific B and T cell responses in mice. Virology (2005) 0.91

Crystal structure of an Aquabirnavirus particle: insights into antigenic diversity and virulence determinism. J Virol (2009) 0.91

Peptides resulting from the pVP2 C-terminal processing are present in infectious pancreatic necrosis virus particles. J Gen Virol (2004) 0.91

The last C-terminal residue of VP3, glutamic acid 257, controls capsid assembly of infectious bursal disease virus. J Virol (2004) 0.89

Genome and polypeptides characterization of Tellina virus 1 reveals a fifth genetic cluster in the Birnaviridae family. Virology (2007) 0.89

Molecular dynamics studies of the nucleoprotein of influenza A virus: role of the protein flexibility in RNA binding. PLoS One (2012) 0.89

Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction. J Biol Chem (2007) 0.88

Assessment of efficacy of antifungals against Aspergillus fumigatus: value of real-time bioluminescence imaging. Antimicrob Agents Chemother (2013) 0.88

Prime and boost immunization with influenza and adenovirus encoding the Toxoplasma gondii surface antigen 2 (SAG2) induces strong protective immunity. Vaccine (2010) 0.87

SUMOylation promotes PML degradation during encephalomyocarditis virus infection. J Virol (2010) 0.87

LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis. Mol Cell Biol (2013) 0.87

Uncoupled embryonic and extra-embryonic tissues compromise blastocyst development after somatic cell nuclear transfer. PLoS One (2012) 0.86

Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target. Future Microbiol (2013) 0.86

Structural peptides of a nonenveloped virus are involved in assembly and membrane translocation. J Virol (2005) 0.84

Structure of birnavirus-like particles determined by combined electron cryomicroscopy and X-ray crystallography. J Gen Virol (2005) 0.84

The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis. J Hepatol (2012) 0.84

Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. II. Immunobiological dysfunctions. PLoS Negl Trop Dis (2010) 0.83

Infectious bursal disease subviral particles displaying the foot-and-mouth disease virus major antigenic site. Vaccine (2008) 0.83

Picobirnaviruses encode a protein with repeats of the ExxRxNxxxE motif. Virus Res (2011) 0.83

Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza. Expert Opin Drug Discov (2015) 0.81

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes. J Virol (2012) 0.80

Spatial, a new nuclear factor tightly regulated during mouse spermatogenesis. Gene Expr Patterns (2003) 0.80

Electrochemical detection of the oligomerization of PB1-F2 influenza A virus protein in infected cells. Anal Chem (2014) 0.80

A novel subnucleocapsid nanoplatform for mucosal vaccination against influenza virus that targets the ectodomain of matrix protein 2. J Virol (2013) 0.80

Heterologous viral RNA export elements improve expression of severe acute respiratory syndrome (SARS) coronavirus spike protein and protective efficacy of DNA vaccines against SARS. Virology (2007) 0.80

Delivery of mengovirus-derived RNA replicons into tumoural liver enhances the anti-tumour efficacy of a peripheral peptide-based vaccine. Cancer Immunol Immunother (2008) 0.79