Published in Curr Eye Res on March 07, 2013
Retinal Ganglion Cell Loss and Mild Vasculopathy in Methylene Tetrahydrofolate Reductase (Mthfr)-Deficient Mice: A Model of Mild Hyperhomocysteinemia. Invest Ophthalmol Vis Sci (2015) 0.95
Hydrogen sulfide: physiological properties and therapeutic potential in ischaemia. Br J Pharmacol (2015) 0.86
FEVR-Like Presentation of Homocystinuria. Case Rep Ophthalmol Med (2014) 0.75
Awareness, knowledge, and risks of zoonotic diseases among livestock farmers in Punjab. Vet World (2016) 0.75
Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc (2008) 62.52
The possible role of hydrogen sulfide as an endogenous neuromodulator. J Neurosci (1996) 6.04
Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. Biochem J (1982) 3.76
Redox biochemistry of hydrogen sulfide. J Biol Chem (2010) 3.64
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia. Proc Natl Acad Sci U S A (1995) 3.51
Hydrogen sulfide induces cyclic AMP and modulates the NMDA receptor. Biochem Biophys Res Commun (2000) 1.67
Hypermethioninemias of genetic and non-genetic origin: A review. Am J Med Genet C Semin Med Genet (2011) 1.55
Expression of the cystine-glutamate exchanger (xc-) in retinal ganglion cells and regulation by nitric oxide and oxidative stress. Cell Tissue Res (2006) 1.32
Cystathionine beta-synthase is enriched in the brains of Down's patients. Biochem Biophys Res Commun (2005) 1.20
Hydrogen sulfide protects the retina from light-induced degeneration by the modulation of Ca2+ influx. J Biol Chem (2011) 1.16
Reaction based fluorescent probes for hydrogen sulfide. Org Lett (2012) 1.14
Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse. Invest Ophthalmol Vis Sci (2009) 1.10
Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. Biochem J (2009) 1.05
Human cystathionine beta-synthase is a target for sumoylation. Biochemistry (2006) 1.05
Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons. Invest Ophthalmol Vis Sci (2011) 1.02
The distribution of cystathionine beta-synthase (CBS) in the eye: implication of the presence of a trans-sulfuration pathway for oxidative stress defense. Exp Eye Res (2006) 1.01
Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells. Invest Ophthalmol Vis Sci (2011) 0.99
Comparative localization of cystathionine beta-synthase and cystathionine gamma-lyase in retina: differences between amphibians and mammals. J Comp Neurol (2007) 0.95
Defects in homocysteine metabolism: diversity among hyperhomocyst(e)inemias. Clin Chem Lab Med (2007) 0.91
Brain phenotype of transgenic mice overexpressing cystathionine β-synthase. PLoS One (2012) 0.87
Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate. Glia (2011) 0.85
H2S signals through protein S-sulfhydration. Sci Signal (2009) 4.54
Death of retinal neurons in streptozotocin-induced diabetic mice. Invest Ophthalmol Vis Sci (2004) 2.62
Nitric oxide donors: chemical activities and biological applications. Chem Rev (2002) 2.55
Down-regulation of placental transport of amino acids precedes the development of intrauterine growth restriction in rats fed a low protein diet. J Physiol (2006) 2.27
GAPDH mediates nitrosylation of nuclear proteins. Nat Cell Biol (2010) 2.22
GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer Res (2009) 1.89
Functional identification of SLC5A8, a tumor suppressor down-regulated in colon cancer, as a Na(+)-coupled transporter for short-chain fatty acids. J Biol Chem (2004) 1.70
Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice. Am J Pathol (2012) 1.69
The novel binding mode of N-alkyl-N'-hydroxyguanidine to neuronal nitric oxide synthase provides mechanistic insights into NO biosynthesis. Biochemistry (2002) 1.65
The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. Antioxid Redox Signal (2012) 1.64
A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance. Mol Cancer Ther (2008) 1.64
Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. J Pharmacol Exp Ther (2008) 1.62
Anion relay chemistry: an effective tactic for diversity oriented synthesis. J Am Chem Soc (2006) 1.60
Antiapoptotic properties of α-crystallin-derived peptide chaperones and characterization of their uptake transporters in human RPE cells. Invest Ophthalmol Vis Sci (2013) 1.59
Capture and visualization of hydrogen sulfide by a fluorescent probe. Angew Chem Int Ed Engl (2011) 1.57
Sulfhydration mediates neuroprotective actions of parkin. Nat Commun (2013) 1.49
The [1,5]-Brook rearrangement: an initial application in anion relay chemistry. J Am Chem Soc (2006) 1.45
Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain. J Neurochem (2006) 1.43
Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function. Biochem Biophys Res Commun (2002) 1.40
SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter. Life Sci (2005) 1.40
Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis. Cancer Res (2010) 1.39
Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. Biochem J (2004) 1.38
Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates. Biochem J (2002) 1.37
Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe. Biochem J (2008) 1.36
Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. J Biol Chem (2002) 1.35
Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand. Invest Ophthalmol Vis Sci (2007) 1.35
SLC19: the folate/thiamine transporter family. Pflugers Arch (2003) 1.34
In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine. Invest Ophthalmol Vis Sci (2008) 1.33
Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem J (2009) 1.32
Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8. J Gastrointest Surg (2009) 1.28
Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain. J Biol Chem (2002) 1.27
Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells. Cancer Res (2007) 1.27
SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases. Cancer Res (2006) 1.25
NF-κB directly regulates Fas transcription to modulate Fas-mediated apoptosis and tumor suppression. J Biol Chem (2012) 1.24
Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. J Biol Chem (2004) 1.24
Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2. J Physiol (2003) 1.23
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate. Brain Res Mol Brain Res (2004) 1.23
Molecular evidence and functional expression of P-glycoprotein (MDR1) in human and rabbit cornea and corneal epithelial cell lines. Invest Ophthalmol Vis Sci (2003) 1.21
Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity. Biochem Pharmacol (2007) 1.21
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer. Cancer Res (2011) 1.21
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells. Invest Ophthalmol Vis Sci (2006) 1.20
H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat. Gastroenterology (2004) 1.20
Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types. Invest Ophthalmol Vis Sci (2007) 1.20
An unexpected Bis-ligation of S-nitrosothiols. J Am Chem Soc (2009) 1.20
Fast reductive ligation of S-nitrosothiols. Angew Chem Int Ed Engl (2008) 1.19
Sodium-coupled transport of the short chain fatty acid butyrate by SLC5A8 and its relevance to colon cancer. J Gastrointest Surg (2008) 1.19
Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases. J Biol Chem (2010) 1.18
Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract. Pharm Res (2007) 1.18
Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells. Am J Physiol Gastrointest Liver Physiol (2012) 1.18
Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. J Pharmacol Exp Ther (2003) 1.17
New fluorescent probes for sulfane sulfurs and the application in bioimaging. Chem Sci (2013) 1.17
Facile formation of dehydroalanine from S-nitrosocysteines. J Am Chem Soc (2009) 1.16
Detection of protein S-sulfhydration by a tag-switch technique. Angew Chem Int Ed Engl (2013) 1.16
Reaction based fluorescent probes for hydrogen sulfide. Org Lett (2012) 1.14
Reductive ligation mediated one-step disulfide formation of S-nitrosothiols. Org Lett (2010) 1.13
Cysteine-activated hydrogen sulfide (H2S) donors. J Am Chem Soc (2010) 1.12
Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium. Mol Vis (2009) 1.12
Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. Biochem J (2003) 1.12
Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family. Biochem J (2005) 1.12
Vasoactive factors in sickle cell disease: in vitro evidence for endothelin-1-mediated vasoconstriction. Am J Hematol (2004) 1.11
Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. Diabetes (2011) 1.11
Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani. FEBS Lett (2004) 1.11
Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse. Invest Ophthalmol Vis Sci (2009) 1.10
Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice. Brain Res Mol Brain Res (2002) 1.10
Exploration of the "traceless" reductive ligation of S-nitrosothiols. Org Lett (2009) 1.10
Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium. Invest Ophthalmol Vis Sci (2006) 1.10
Chemical methods to detect S-nitrosation. Curr Opin Chem Biol (2010) 1.10
Anion relay chemistry extended. Synthesis of a gorgonian sesquiterpene. Org Lett (2007) 1.09
c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney. J Biol Chem (2006) 1.09
IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression. J Immunol (2007) 1.08
Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells. Invest Ophthalmol Vis Sci (2005) 1.08
Controllable hydrogen sulfide donors and their activity against myocardial ischemia-reperfusion injury. ACS Chem Biol (2013) 1.07
Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium. Invest Ophthalmol Vis Sci (2004) 1.07
Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: a possible target for combination therapy with anti-proliferative aminopeptidase inhibitors. Biochem Pharmacol (2010) 1.06
Inositol polyphosphate multikinase is a coactivator of p53-mediated transcription and cell death. Sci Signal (2013) 1.06
Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. Biochem J (2009) 1.05
An anti-tumor role for cGMP-dependent protein kinase. Cancer Lett (2005) 1.05
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin. Am J Physiol Cell Physiol (2004) 1.05
Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger. Biochem J (2009) 1.05