Phase I study of the CD40 agonist antibody CP-870,893 combined with carboplatin and paclitaxel in patients with advanced solid tumors.

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Published in Oncoimmunology on January 01, 2013

Authors

Robert H Vonderheide1, Jennifer M Burg, Rosemarie Mick, Jennifer A Trosko, Dongguang Li, M Naveed Shaik, Anthony W Tolcher, Omid Hamid

Author Affiliations

1: Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.

Associated clinical trials:

Tremelimumab and CP-870,893 in Patients With Metastatic Melanoma | NCT01103635

Dose Finding Study Of CP-870,893, An Immune System Stimulating Antibody, In Combination With Paclitaxel And Carboplatin For Patients With Metastatic Solid Tumors | NCT00607048

Phase 1 Study of Preoperative Gemcitabine Plus CP-870, 893 Followed by Addition of CP-870,893 to Standard -Of-care Adjuvant Chemoradiation for Patients With Newly Diagnosed Resectable Pancreatic Carcinoma | NCT01456585

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