Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion.

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Published in Cancer Res on February 09, 2007

Authors

Brian J Czerniecki1, Gary K Koski, Ursula Koldovsky, Shuwen Xu, Peter A Cohen, Rosemarie Mick, Harvey Nisenbaum, Terry Pasha, Min Xu, Kevin R Fox, Susan Weinstein, Susan G Orel, Robert Vonderheide, George Coukos, Angela DeMichele, Louis Araujo, Francis R Spitz, Mark Rosen, Bruce L Levine, Carl June, Paul J Zhang

Author Affiliations

1: Department of Surgery, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. brian.czerniecki@uphs.upenn.edu

Associated clinical trials:

HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer Post Neoadjuvant Chemotherapy (Neoadjuvant) | NCT02061423

HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer (Adjuvant) | NCT02063724

DC Vaccine for Patients With Ductal Carcinoma In Situ (DCIS6) | NCT02061332

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