Published in Am J Pathol on May 01, 1990
Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice. J Clin Invest (1992) 1.81
Immune-mediated inflammation directly impairs pulmonary function, contributing to the pathogenesis of Pneumocystis carinii pneumonia. J Clin Invest (1999) 1.69
Reduced binding and phagocytosis of Pneumocystis carinii by alveolar macrophages from persons infected with HIV-1 correlates with mannose receptor downregulation. J Clin Invest (1998) 1.61
Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none. Nat Rev Microbiol (2012) 1.45
Interleukin 1: an important mediator of host resistance against Pneumocystis carinii. J Exp Med (1992) 1.36
Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia. J Immunol (2006) 1.31
SCID mouse models of acute and relapsing chronic Toxoplasma gondii infections. Infect Immun (1992) 1.30
Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts. Infect Immun (2003) 1.29
Single and combined humoral and cell-mediated immunotherapy of Pneumocystis carinii pneumonia in immunodeficient scid mice. Infect Immun (1993) 1.22
Chemokine gene expression during Pneumocystis carinii-driven pulmonary inflammation. Infect Immun (1999) 1.17
Neither neutrophils nor reactive oxygen species contribute to tissue damage during Pneumocystis pneumonia in mice. Infect Immun (2004) 1.17
Pneumocystis activates human alveolar macrophage NF-kappaB signaling through mannose receptors. Infect Immun (2004) 1.16
Development and resolution of Pneumocystis carinii pneumonia in severe combined immunodeficient mice: a morphological study of host inflammatory responses. Int J Exp Pathol (1992) 1.15
Interleukin-6 production in a murine model of Pneumocystis carinii pneumonia: relation to resistance and inflammatory response. Infect Immun (1993) 1.13
Pulmonary hypertension can be a sequela of prior Pneumocystis pneumonia. Am J Pathol (2007) 1.05
Immune responses to Pneumocystis murina are robust in healthy mice but largely absent in CD40 ligand-deficient mice. J Leukoc Biol (2008) 1.01
The immunology of parasite infections in immunocompromised hosts. Parasite Immunol (2006) 1.01
Mouse model for Pneumocystis carinii pneumonia that uses natural transmission to initiate infection. Infect Immun (1992) 1.01
Dectin immunoadhesins and pneumocystis pneumonia. Infect Immun (2013) 0.88
Immunodeficient and immunosuppressed mice as models to test anti-Pneumocystis carinii drugs. Antimicrob Agents Chemother (1997) 0.87
Pneumocystis Pneumonia in Human Immunodeficiency Virus-infected Adults and Adolescents: Current Concepts and Future Directions. Clin Med Insights Circ Respir Pulm Med (2015) 0.85
Prophylactic effect of FK463, a novel antifungal lipopeptide, against Pneumocystis carinii infection in mice. Antimicrob Agents Chemother (2000) 0.85
Lethal exacerbation of Pneumocystis carinii pneumonia in severe combined immunodeficiency mice after infection by pneumonia virus of mice. J Exp Med (1993) 0.84
Complexity of the MSG gene family of Pneumocystis carinii. BMC Genomics (2009) 0.83
Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis. J Immunol (2013) 0.79
Exacerbation of Pneumocystis carinii pneumonia in immunodeficient (scid) mice by concurrent infection with a pneumovirus. Infect Immun (1993) 0.77
Pulmonary IL-17+ Lymphocytes Increase During Pneumocystis murina Infection But Are Not Required for Clearance of Pneumocystis. Infect Immun (2017) 0.75
The trophic life cycle stage of the opportunistic fungal pathogen Pneumocystis murina hinders the ability of dendritic cells to stimulate CD4(+) T cell responses. Infect Immun (2017) 0.75
A severe combined immunodeficiency mutation in the mouse. Nature (1983) 13.99
The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science (1988) 9.05
Latent Pneumocystis infection of rats, relapse, and chemotherapy. Lab Invest (1966) 7.58
Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature (1988) 6.38
Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the fungi. Nature (1988) 5.21
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell (1986) 4.68
Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid). J Immunol (1985) 3.69
Evidence of functional lymphocytes in some (leaky) scid mice. J Exp Med (1988) 3.09
Propagation of Pneumocystis carinii in vitro. Pediatr Res (1977) 2.92
Parasitologic and serologic observations of infection with Pneumocystis in humans. J Infect Dis (1977) 2.90
Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms. Am J Pathol (1985) 2.80
Natural mode of acquisition for de novo infection with Pneumocystis carinii. J Infect Dis (1982) 2.80
The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism. Cell (1988) 2.71
Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease. J Immunol (1984) 2.56
Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism. J Immunol (1986) 2.51
Growth characteristics and pathogenesis of experimental Pneumocystis carinii pneumonia. Infect Immun (1980) 2.33
Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice. Science (1986) 2.24
Pneumocystis carinii and Toxoplasma gondii infections in patients with AIDS. Rev Infect Dis (1987) 2.19
Nude mouse: a new experimental model for Pneumocystis carinii infection. Science (1977) 2.16
A comparison of the antigenic characteristics of rat and human Pneumocystis carinii by immunoblotting. J Immunol (1987) 1.98
Protein-calorie malnutrition. A host determinant for Pneumocystis carinii infection. Am J Dis Child (1974) 1.55
Pneumocystis carinii pneumonitis in children with malignancies. J Pediatr (1973) 1.49
Pathology of Listeria infection in murine severe combined immunodeficiency. A study by immunohistochemistry and electron microscopy. Lab Invest (1988) 1.45
Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice. Infect Immun (1989) 1.43
The mouse mutation severe combined immune deficiency (scid) is on chromosome 16. Immunogenetics (1989) 1.41
Monocyte-mediated serum-independent damage to hyphal and pseudohyphal forms of Candida albicans in vitro. J Clin Invest (1981) 1.38
The function of antigen-presenting cells in mice with severe combined immunodeficiency. J Immunol (1985) 1.36
Immunologic events in experimental hypersensitivity granulomas. Am J Pathol (1973) 1.34
Experimental Pneumocystis carinii infection in nude rats. Jpn J Exp Med (1984) 1.31
Intensity of immunosuppressive therapy and the incidence of Pneumocystis carinii pneumonitis. Cancer (1975) 1.22
Inoculation candidiasis in a murine model of severe combined immunodeficiency syndrome. Infect Immun (1988) 1.21
An expanded population of natural killer cells in mice with severe combined immunodeficiency (SCID) lack rearrangement and expression of T cell receptor genes. J Exp Med (1986) 1.19
Infection and immunoglobulin concentrations in Chediak-Higashi mice. Infect Immun (1974) 1.15
Pneumocystis carinii pneumonia and primary immune deficiency diseases of infancy and childhood. J Pediatr (1973) 1.01
Analysis of erythroid homeostatic mechanisms in normal and genetically anaemic mice. Br J Haematol (1966) 0.99
Early B-cell precursors in scid mice: normal numbers of cells transformable with Abelson murine leukemia virus (A-MuLV). Cell Immunol (1988) 0.99
Fatal pneumonia with terminal emaciation in nude mice caused by pneumonia virus of mice. Lab Anim Sci (1988) 0.93
ERYTHROPOIETIC RESPONSE IN CHRONIC PULMONARY DISEASE. Arch Intern Med (1964) 0.81
Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science (1994) 10.04
Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry (2001) 6.75
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell (1990) 6.17
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem (2001) 4.51
Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet (1997) 3.85
Linkage of prion protein and scrapie incubation time genes. Cell (1986) 3.69
Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for an active role of microtubules in cytoplasmic transport. J Cell Biol (1985) 3.58
Increased resistance to oxidative stress in transgenic plants that overexpress chloroplastic Cu/Zn superoxide dismutase. Proc Natl Acad Sci U S A (1993) 3.56
The contractile basis of amoeboid movement. I. The chemical control of motility in isolated cytoplasm. J Cell Biol (1973) 3.49
Distinct prion proteins in short and long scrapie incubation period mice. Cell (1987) 3.21
Fast axonal transport in extruded axoplasm from squid giant axon. Science (1982) 3.19
Taxonomy of aerobic marine eubacteria. J Bacteriol (1972) 3.09
Fast axonal transport in squid giant axon. Science (1982) 2.96
Structure and arrangement of flagella in species of the genus Beneckea and Photobacterium fischeri. J Bacteriol (1971) 2.93
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol (1999) 2.92
The zeiss-Nomarski differential interference equipment for transmitted-light microscopy. Z Wiss Mikrosk (1969) 2.91
Video-enhanced contrast, differential interference contrast (AVEC-DIC) microscopy: a new method capable of analyzing microtubule-related motility in the reticulopodial network of Allogromia laticollaris. Cell Motil (1981) 2.80
Lyme borreliosis in genetically resistant and susceptible mice with severe combined immunodeficiency. Am J Trop Med Hyg (1992) 2.71
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell (1994) 2.68
"Viable motheaten," a new allele at the motheaten locus. I. Pathology. Am J Pathol (1984) 2.26
Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice. Science (1986) 2.24
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat Neurosci (1999) 2.21
Gamma-interferon is one of several direct B cell-maturing lymphokines. Nature (1984) 2.18
Fine structure, reconstruction and possible functions of components of the cortex of Tetrahymena pyriformis. J Protozool (1967) 2.17
Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell (1996) 2.04
The morphogenesis of basal bodies and accessory structures of the cortex of the ciliated protozoan Tetrahymena pyriformis. J Cell Biol (1969) 2.02
The role of domestic animals in the epidemiology of plague. II. Antibody to Yersinia pestis in sera of dogs and cats. J Infect Dis (1971) 1.99
Genetically determined murine models of immunodeficiency. Annu Rev Immunol (1987) 1.98
Video microscopy of fast axonal transport in extruded axoplasm: a new model for study of molecular mechanisms. Cell Motil (1985) 1.95
Rheological properties of living cytoplasm: a preliminary investigation of squid axoplasm (Loligo pealei). Cell Motil (1984) 1.91
Receptor-mediated inactivation of early B lymphocytes. Nature (1975) 1.90
Cytoplasmic transport in keratocytes: direct visualization of particle translocation along microtubules. Cell Motil (1983) 1.90
Overexpression of glutathione S-transferase/glutathione peroxidase enhances the growth of transgenic tobacco seedlings during stress. Nat Biotechnol (1997) 1.88
Plague in Vietnam 1965-1966. Am J Epidemiol (1967) 1.87
Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice. J Clin Invest (1992) 1.81
Video-enhanced microscopy with a computer frame memory. J Microsc (1983) 1.78
Alms1-disrupted mice recapitulate human Alström syndrome. Hum Mol Genet (2005) 1.77
Dissociation of two signals required for activation of resting B cells. Proc Natl Acad Sci U S A (1982) 1.74
The role of domestic animals in the epidemiology of plague. I. Experimental infection of dogs and cats. J Infect Dis (1971) 1.74
Quantitative trait loci affecting prion incubation time in mice. Genomics (2000) 1.73
Transformation and motility of human platelets: details of the shape change and release reaction observed by optical and electron microscopy. J Cell Biol (1979) 1.73
Bacteroides gingivalis and Bacteroides intermedius recognize different sites on human fibrinogen. J Bacteriol (1990) 1.69
Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation. Proc Natl Acad Sci U S A (2000) 1.66
Development of B lymphocytes. I. Cell populations and a critical event during ontogeny. J Immunol (1975) 1.65
Monoclonal antibodies with a high degree of specificity for Listeria monocytogenes serotype 4b. Appl Environ Microbiol (1994) 1.60
Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules. J Exp Med (1976) 1.59
Structure and organization of the living mitotic spindle of Haemanthus endosperm. Science (1966) 1.59
Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules. J Exp Med (1990) 1.56
Exogenous A beta1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice. J Cereb Blood Flow Metab (2000) 1.55
Isolation, enumeration, and host range of marine Bdellovibrios. Arch Microbiol (1974) 1.53
Plague immunization. II. Relation of adverse clinical reactions to multiple immunizations with killed vaccine. J Infect Dis (1974) 1.52
Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med (1993) 1.51
Antibody and resistance to infection with Yersinia pestis in the progeny of immunized rats. J Infect Dis (1974) 1.51
ECT and prepubertal children. J Am Acad Child Adolesc Psychiatry (1995) 1.50
Routine chest roentgenography is unnecessary in the work-up of stage I and II breast cancer. J Clin Oncol (2000) 1.50
Large numbers of primitive stem cells are active simultaneously in aggregated embryo chimeric mice. Blood (1987) 1.46
Some observations on the necessity for serological testing of rodent sera for Pasteurella pestis antibody in a plague control programme. Bull World Health Organ (1970) 1.46
Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice. Eur J Immunol (1992) 1.44
The influence of climate on the seasonal prevalence of plague in the Republic of Vietnam. J Wildl Dis (1972) 1.44
Cytoplasmic streaming in green plants. Annu Rev Biophys Bioeng (1978) 1.44
Plague immunization. V. Indirect evidence for the efficacy of plague vaccine. J Infect Dis (1974) 1.43
Some observations on the current plague outbreak in the Republic of Vietnam. Am J Public Health Nations Health (1968) 1.42
Plague immunization. I. Past and present trends. J Infect Dis (1974) 1.42
Specific cell components of Bacteroides gingivalis mediate binding and degradation of human fibrinogen. J Bacteriol (1991) 1.42
A 10,000-step count as a physical activity target for sedentary women. Res Q Exerc Sport (2001) 1.41
Posttransplant cataract: lessons from kidney-pancreas transplantation. Transplantation (2000) 1.41
Childhood-onset psychosis: evolution and comorbidity. Am J Psychiatry (1997) 1.39
Identification of Porphyromonas gingivalis components that mediate its interactions with fibronectin. J Bacteriol (1991) 1.39
Progression of macrovascular disease after transplantation. Transplantation (2000) 1.39
Stress tolerance in transgenic tobacco seedlings that overexpress glutathione S-transferase/glutathione peroxidase. Plant Cell Physiol (2000) 1.38
Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules. J Clin Invest (1995) 1.37
Gelsolin inhibition of fast axonal transport indicates a requirement for actin microfilaments. Nature (1984) 1.37
Mutations in Cdh23 cause nonsyndromic hearing loss in waltzer mice. Genomics (2001) 1.37
Translocation of vesicles from squid axoplasm on flagellar microtubules. Nature (1985) 1.36
Expression and function of IL-12 and IL-18 receptors on human tonsillar B cells. J Immunol (2000) 1.34
Inhibition of phytoalexin synthesis in arachidonic Acid-stressed potato tissue by inhibitors of lipoxygenase and cyanide-resistant respiration. Plant Physiol (1983) 1.32
A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice. Eur J Immunol (1994) 1.32
Differential cytokine expression in acute and chronic murine graft-versus-host-disease. Eur J Immunol (1993) 1.31
New observations on cell architecture and dynamics by video-enhanced contrast optical microscopy. Annu Rev Biophys Biophys Chem (1985) 1.31
Major histocompatibility complex-restricted cellular interactions determining B cell activation. Eur J Immunol (1982) 1.30
Detection of single microtubules in living cells: particle transport can occur in both directions along the same microtubule. J Cell Biol (1984) 1.30
Mitochondrial motility in axons: membranous organelles may interact with the force generating system through multiple surface binding sites. Cell Motil (1984) 1.30
Rheological properties of living cytoplasm: endoplasm of Physarum plasmodium. J Cell Biol (1983) 1.30
The stages of mania. A longitudinal analysis of the manic episode. Arch Gen Psychiatry (1973) 1.29
Control of proliferation and differentiation in B lymphocytes by anti-Ig antibodies and a serum-derived cofactor. Proc Natl Acad Sci U S A (1978) 1.28
Evidence for firm linkages between microtubules and membrane-bounded vesicles. J Cell Biol (1975) 1.28
A beta-peptides enhance vasoconstriction in cerebral circulation. Am J Physiol Heart Circ Physiol (2001) 1.26
Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice. Nat Genet (1997) 1.24
Structure and polymorphism of the mouse prion protein gene. Proc Natl Acad Sci U S A (1994) 1.24
Effect of histological damage on long-term kidney transplant outcome. Transplantation (2001) 1.24
Apoptosis and macrophage-mediated deletion of precursor B cells in the bone marrow of E mu-myc transgenic mice. Blood (1994) 1.23
Identification of candidate proteins binding to prion protein. Neurobiol Dis (1997) 1.23
Specificities and V genes encoding monoclonal autoantibodies from viable motheaten mice. J Exp Med (1988) 1.23
Structural organization associated with pseudopod extension and contraction during cell locomotion in Difflugia. J Cell Sci (1968) 1.22
Video-enhanced contrast polarization (AVEC-POL) microscopy: a new method applied to the detection of birefringence in the motile reticulopodial network of Allogromia laticollaris. Cell Motil (1981) 1.22
Single and combined humoral and cell-mediated immunotherapy of Pneumocystis carinii pneumonia in immunodeficient scid mice. Infect Immun (1993) 1.22
Plague immunization. 3. Serologic response to multiple inoculations of vaccine. J Infect Dis (1974) 1.22
Ecology of plague in Vietnam. I. Role of Suncus murinus. Proc Soc Exp Biol Med (1967) 1.22