Published in Mol Aspects Med on March 19, 2013
The Concise Guide to PHARMACOLOGY 2013/14: transporters. Br J Pharmacol (2013) 2.07
Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids. Nat Med (2014) 1.04
Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids. Biochem Biophys Res Commun (2013) 0.85
Exogenous Fatty Acids Are the Preferred Source of Membrane Lipids in Proliferating Fibroblasts. Cell Chem Biol (2016) 0.84
Obesity and cancer progression: is there a role of fatty acid metabolism? Biomed Res Int (2015) 0.84
Large number of putative chemoreception and pheromone biosynthesis genes revealed by analyzing transcriptome from ovipositor-pheromone glands of Chilo suppressalis. Sci Rep (2015) 0.83
Dependence of brown adipose tissue function on CD36-mediated coenzyme Q uptake. Cell Rep (2015) 0.83
All-trans retinoic acid regulates hepatic bile acid homeostasis. Biochem Pharmacol (2014) 0.82
Fatty acid transporters in skin development, function and disease. Biochim Biophys Acta (2013) 0.82
The effect of tomato juice supplementation on biomarkers and gene expression related to lipid metabolism in rats with induced hepatic steatosis. Eur J Nutr (2014) 0.80
Fatty acid transport protein 1 can compensate for fatty acid transport protein 4 in the developing mouse epidermis. J Invest Dermatol (2014) 0.79
Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans. Hepatology (2016) 0.78
Proteoliposomes as tool for assaying membrane transporter functions and interactions with xenobiotics. Pharmaceutics (2013) 0.78
Measurement of long-chain fatty acid uptake into adipocytes. Methods Enzymol (2014) 0.77
Carnitine transport and fatty acid oxidation. Biochim Biophys Acta (2016) 0.76
Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity. Biochem Biophys Res Commun (2015) 0.76
Lipid profiling and transcriptomic analysis reveals a functional interplay between estradiol and growth hormone in liver. PLoS One (2014) 0.76
11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Mol Metab (2014) 0.76
Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse. PLoS One (2016) 0.75
Fatty Acid Transport Proteins: Targeting FATP2 as a Gatekeeper Involved in the Transport of Exogenous Fatty Acids. Medchemcomm (2016) 0.75
Prevention of gallbladder hypomotility via FATP2 inhibition protects from lithogenic diet-induced cholelithiasis. Am J Physiol Gastrointest Liver Physiol (2016) 0.75
TNF-α stimulates endothelial palmitic acid transcytosis and promotes insulin resistance. Sci Rep (2017) 0.75
Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism. Trends Endocrinol Metab (2017) 0.75
Early Trypanosoma cruzi infection reprograms human epithelial cells. Biomed Res Int (2014) 0.75
The transcriptome of the Didelphis virginiana opossum kidney OK proximal tubule cell line. Am J Physiol Renal Physiol (2017) 0.75
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A (1994) 6.46
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell (1994) 4.33
Vascular endothelial growth factor B controls endothelial fatty acid uptake. Nature (2010) 3.40
Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. J Biol Chem (2000) 2.85
Identification of the major intestinal fatty acid transport protein. Mol Cell (1999) 2.65
Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res (2004) 2.50
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest (2004) 2.12
A family of fatty acid transporters conserved from mycobacterium to man. Proc Natl Acad Sci U S A (1998) 2.12
Fat cell adrenergic receptors and the control of white and brown fat cell function. J Lipid Res (1993) 1.90
Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors. J Biol Chem (1995) 1.88
Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators. J Biol Chem (1997) 1.84
Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. J Cell Biol (2003) 1.73
FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Mol Cell Biol (2006) 1.70
Insulin causes fatty acid transport protein translocation and enhanced fatty acid uptake in adipocytes. Dev Cell (2002) 1.67
Mutations in the fatty acid transport protein 4 gene cause the ichthyosis prematurity syndrome. Am J Hum Genet (2009) 1.53
Cellular uptake of fatty acids driven by the ER-localized acyl-CoA synthetase FATP4. J Cell Sci (2006) 1.52
Liver fatty acid-binding protein targets fatty acids to the nucleus. Real time confocal and multiphoton fluorescence imaging in living cells. J Biol Chem (2002) 1.47
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology (2006) 1.45
Placental regulation of fatty acid delivery and its effect on fetal growth--a review. Placenta (2002) 1.40
Fatty acid transport in Saccharomyces cerevisiae. Directed mutagenesis of FAT1 distinguishes the biochemical activities associated with Fat1p. J Biol Chem (2002) 1.38
Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. Proc Natl Acad Sci U S A (2003) 1.35
Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation. Biochim Biophys Acta (2006) 1.34
Fatty acid metabolism in adipocytes: functional analysis of fatty acid transport proteins 1 and 4. J Lipid Res (2006) 1.34
Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia. J Biol Chem (2008) 1.32
Enzymatic properties of purified murine fatty acid transport protein 4 and analysis of acyl-CoA synthetase activities in tissues from FATP4 null mice. J Biol Chem (2005) 1.29
Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts. J Biol Chem (2007) 1.29
Identification of a functional peroxisome proliferator-responsive element in the murine fatty acid transport protein gene. J Biol Chem (1999) 1.29
Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids. J Biol Chem (1997) 1.29
Characterization of a heart-specific fatty acid transport protein. J Biol Chem (2003) 1.28
Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes. J Lipid Res (2005) 1.28
Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem (2003) 1.26
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase. Am J Physiol Endocrinol Metab (2010) 1.26
Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. Am J Physiol Gastrointest Liver Physiol (2008) 1.26
Fatty acid transport proteins, implications in physiology and disease. Biochim Biophys Acta (2011) 1.26
Mouse fatty acid transport protein 4 (FATP4): characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase. Gene (2001) 1.24
The fatty acid transport protein (FATP1) is a very long chain acyl-CoA synthetase. J Biol Chem (1999) 1.22
A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids. Lipids (2001) 1.21
Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue. Diabetes (2006) 1.16
Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity. Gastroenterology (2006) 1.16
Abnormalities of glucose metabolism associated with atypical antipsychotic drugs. J Clin Psychiatry (2004) 1.15
Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast. J Biol Chem (2005) 1.15
Disruption of the Saccharomyces cerevisiae FAT1 gene decreases very long-chain fatty acyl-CoA synthetase activity and elevates intracellular very long-chain fatty acid concentrations. J Biol Chem (1998) 1.14
Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle. J Biol Chem (2009) 1.13
Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart. Cardiovasc Res (2006) 1.11
Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem (2003) 1.11
Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking. Arch Biochem Biophys (2008) 1.11
FATP4 missense and nonsense mutations cause similar features in Ichthyosis Prematurity Syndrome. BMC Res Notes (2011) 1.10
Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease. Hepatol Res (2008) 1.08
Fatty acid transport across the cell membrane: regulation by fatty acid transporters. Prostaglandins Leukot Essent Fatty Acids (2010) 1.07
Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance. Diabetologia (2004) 1.06
Keratinocyte-specific expression of fatty acid transport protein 4 rescues the wrinkle-free phenotype in Slc27a4/Fatp4 mutant mice. J Biol Chem (2007) 1.05
The Saccharomyces cerevisiae FAT1 gene encodes an acyl-CoA synthetase that is required for maintenance of very long chain fatty acid levels. J Biol Chem (1999) 1.04
Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling. J Biol Chem (2002) 1.04
Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase. J Biol Chem (1996) 1.03
Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells. J Neurochem (2011) 1.03
Fatty acid transport protein 4 is dispensable for intestinal lipid absorption in mice. J Lipid Res (2008) 1.03
Membrane topology of the murine fatty acid transport protein 1. J Biol Chem (2001) 1.00
Disturbed epidermal structure in mice with temporally controlled fatp4 deficiency. J Invest Dermatol (2005) 0.99
Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells. J Biol Chem (2004) 0.98
Differential expression of fatty acid transport proteins in epidermis and skin appendages. J Invest Dermatol (2005) 0.98
Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6. FEBS Lett (2009) 0.98
A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors. Anal Biochem (2005) 0.97
The expression and function of fatty acid transport protein-2 and -4 in the murine placenta. PLoS One (2011) 0.96
Overexpression of CD36 and acyl-CoA synthetases FATP2, FATP4 and ACSL1 increases fatty acid uptake in human hepatoma cells. Int J Med Sci (2011) 0.96
Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking. Novartis Found Symp (2007) 0.94
High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias. J Lipid Res (2007) 0.94
Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol. J Biol Chem (2011) 0.92
Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4. Bioorg Med Chem Lett (2006) 0.91
A very long-chain acyl-CoA synthetase-deficient mouse and its relevance to X-linked adrenoleukodystrophy. Hum Mol Genet (2003) 0.90
Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein. Mol Genet Metab (1999) 0.90
The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase. J Biol Chem (2000) 0.90
Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans. Am J Physiol Endocrinol Metab (2000) 0.89
Oligomerization of the murine fatty acid transport protein 1. J Biol Chem (2003) 0.89
Identification and characterization of small compound inhibitors of human FATP2. Biochem Pharmacol (2009) 0.87
Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet. J Biol Chem (2011) 0.87
Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol (2010) 0.85
A promoter polymorphism in the liver-specific fatty acid transport protein 5 is associated with features of the metabolic syndrome and steatosis. Horm Metab Res (2010) 0.84
Molecular cloning and expression of rat liver bile acid CoA ligase. J Lipid Res (2002) 0.84
Tissue distribution and cDNA cloning of a human fatty acid transport protein (hsFATP4). Biochim Biophys Acta (1998) 0.83
Regulation of the murine adipocyte fatty acid transporter gene by insulin. Mol Endocrinol (1996) 0.82
Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome. J Clin Endocrinol Metab (2004) 0.82
Characterization of the murine fatty acid transport protein gene and its insulin response sequence. J Biol Chem (1998) 0.81
TR4 activates FATP1 gene expression to promote lipid accumulation in 3T3-L1 adipocytes. FEBS Lett (2011) 0.81
Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5. J Biomol Screen (2010) 0.80
Increasing skeletal muscle fatty acid transport protein 1 (FATP1) targets fatty acids to oxidation and does not predispose mice to diet-induced insulin resistance. Diabetologia (2011) 0.80
A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution. Atherosclerosis (2003) 0.80
ApoB siRNA-induced liver steatosis is resistant to clearance by the loss of fatty acid transport protein 5 (Fatp5). Lipids (2011) 0.79
Intronic polymorphism in the fatty acid transport protein 1 gene is associated with increased plasma triglyceride levels in a French population. Arterioscler Thromb Vasc Biol (2000) 0.79
Structural and functional characterization of the bovine solute carrier family 27 member 1 (SLC27A1) gene. Cytogenet Genome Res (2006) 0.78
A variant in the heart-specific fatty acid transport protein 6 is associated with lower fasting and postprandial TAG, blood pressure and left ventricular hypertrophy. Br J Nutr (2011) 0.76
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A (2004) 3.40
Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc (2009) 3.31
Propranolol inhibition of β-adrenergic receptor does not suppress pathologic neovascularization in oxygen-induced retinopathy. Invest Ophthalmol Vis Sci (2012) 2.19
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. J Clin Invest (2004) 2.12
Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. J Lipid Res (2004) 2.08
Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A. Blood (2011) 2.02
FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity. Mol Cell Biol (2006) 1.70
5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids. Sci Transl Med (2011) 1.63
Current update on retinopathy of prematurity: screening and treatment. Curr Opin Pediatr (2011) 1.50
Protein-mediated fatty acid uptake: novel insights from in vivo models. Physiology (Bethesda) (2006) 1.48
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology (2006) 1.45
Silencing of hepatic fatty acid transporter protein 5 in vivo reverses diet-induced non-alcoholic fatty liver disease and improves hyperglycemia. J Biol Chem (2008) 1.32
Characterization of a heart-specific fatty acid transport protein. J Biol Chem (2003) 1.28
Targeted deletion of fatty acid transport protein-4 results in early embryonic lethality. J Biol Chem (2003) 1.26
FATP2 is a hepatic fatty acid transporter and peroxisomal very long-chain acyl-CoA synthetase. Am J Physiol Endocrinol Metab (2010) 1.26
Fatty acid transport proteins, implications in physiology and disease. Biochim Biophys Acta (2011) 1.26
Real-time quantification of fatty acid uptake using a novel fluorescence assay. J Lipid Res (2004) 1.21
Wnt signaling mediates pathological vascular growth in proliferative retinopathy. Circulation (2011) 1.18
Fatty acid transport protein 1 is required for nonshivering thermogenesis in brown adipose tissue. Diabetes (2006) 1.16
Mice deleted for fatty acid transport protein 5 have defective bile acid conjugation and are protected from obesity. Gastroenterology (2006) 1.16
Real-time noninvasive imaging of fatty acid uptake in vivo. ACS Chem Biol (2012) 1.06
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1. Cell Metab (2013) 1.05
Specific bile acids inhibit hepatic fatty acid uptake in mice. Hepatology (2012) 1.01
Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice. Invest Ophthalmol Vis Sci (2011) 0.99
Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model. Biol Chem (2008) 0.98
Differential expression of fatty acid transport proteins in epidermis and skin appendages. J Invest Dermatol (2005) 0.98
The expression and function of fatty acid transport protein-2 and -4 in the murine placenta. PLoS One (2011) 0.96
Triglyceride accumulation in injured renal tubular cells: alterations in both synthetic and catabolic pathways. Kidney Int (2005) 0.95
Semaphorin 3F forms an anti-angiogenic barrier in outer retina. FEBS Lett (2013) 0.94
Levels of VEGF but not VEGF(165b) are increased in the vitreous of patients with retinal vein occlusion. Am J Ophthalmol (2011) 0.94
Neuron restrictive silencer factor NRSF/REST is a transcriptional repressor of neuropilin-1 and diminishes the ability of semaphorin 3A to inhibit keratinocyte migration. J Biol Chem (2005) 0.93
Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk. J Clin Invest (2014) 0.92
Retinal expression of Wnt-pathway mediated genes in low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice. PLoS One (2012) 0.90
A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem Biol (2013) 0.88
Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report. Arterioscler Thromb Vasc Biol (2014) 0.88
Development and characterization of a spheroidal coculture model of endothelial cells and fibroblasts for improving angiogenesis in tissue engineering. Cells Tissues Organs (2005) 0.88
Enhanced fatty acid oxidation and FATP4 protein expression after endurance exercise training in human skeletal muscle. PLoS One (2012) 0.85
Endothelial lipase is synthesized by hepatic and aorta endothelial cells and its expression is altered in apoE-deficient mice. J Lipid Res (2004) 0.84
Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a. Invest Ophthalmol Vis Sci (2011) 0.83
Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy. Angiogenesis (2013) 0.83
Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5. J Biomol Screen (2010) 0.80
A biocompatible "split luciferin" reaction and its application for non-invasive bioluminescent imaging of protease activity in living animals. Curr Protoc Chem Biol (2014) 0.80
Hyperoxia causes reduced density of retinal astrocytes in the central avascular zone in the mouse model of oxygen-induced retinopathy. Mol Cell Neurosci (2013) 0.79
Myocardial macronutrient transporter adaptations in the adult pregestational female intrauterine and postnatal growth-restricted offspring. Am J Physiol Endocrinol Metab (2012) 0.78
Intra- and postoperative risks and complications of small-gauge (23-G) versus conventional (20-G) vitrectomy for macular surgery. Eur J Ophthalmol (2014) 0.77
In Reply. Dtsch Arztebl Int (2016) 0.75
A case of mistaken identity. Am J Physiol Heart Circ Physiol (2005) 0.75
Ensemble modeling of very small ZnO nanoparticles. Phys Chem Chem Phys (2010) 0.75
WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. Lab Chip (2017) 0.75
Reduction of vascular endothelial growth factor a in human breast milk after intravitreal injection of bevacizumab but not ranibizumab. Arch Ophthalmol (2012) 0.75