Published in PLoS One on March 26, 2013
A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion. J Virol (2017) 1.01
DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA. PLoS One (2015) 0.78
Human Herpesvirus-6 U14 Induces Cell-Cycle Arrest in G2/M Phase by Associating with a Cellular Protein, EDD. PLoS One (2015) 0.78
Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science (1998) 17.91
Blinded by the Light: The Growing Complexity of p53. Cell (2009) 17.75
PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell (2001) 11.04
Rosette-forming human lymphoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst (1972) 10.15
Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet (1988) 8.76
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science (2000) 8.74
p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell (2000) 5.64
Virus inhibition of RIP3-dependent necrosis. Cell Host Microbe (2010) 3.70
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature (1995) 3.56
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol (2002) 3.55
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe (2012) 3.23
Heterogeneity of malignant cells from a human colonic carcinoma. Cancer Res (1981) 3.12
Seroepidemiology of human herpesvirus 6 infection in normal children and adults. J Clin Microbiol (1989) 2.58
Many stimuli pull the necrotic trigger, an overview. Cell Death Differ (2011) 2.55
Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene (1994) 2.52
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol Cell (2007) 2.18
Latent human herpesvirus 6 infection of human monocytes/macrophages. J Gen Virol (1991) 2.05
The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro. Proc Natl Acad Sci U S A (2010) 1.82
The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53. Virology (2008) 1.65
Massively regulated genes: the example of TP53. J Pathol (2010) 1.46
Chromosomal integration of human herpesvirus 6 is the major mode of congenital human herpesvirus 6 infection. Pediatrics (2008) 1.44
IgG antibodies to human herpesvirus-6 in young children: changes in avidity of antibody correlate with time after infection. J Med Virol (1993) 1.41
Potential role for p53 in the permissive life cycle of human cytomegalovirus. J Virol (2006) 1.40
Association of human herpesvirus-6B with mesial temporal lobe epilepsy. PLoS Med (2007) 1.32
A model for the computer analysis of synchronous DNA distributions obtained by flow cytometry. Cytometry (1980) 1.26
Human herpesvirus-6 infection in bone marrow transplantation. Blood (1991) 1.25
p38 MAPK in regulating cellular responses to ultraviolet radiation. J Biomed Sci (2007) 1.13
Human herpesvirus 6 latently infects early bone marrow progenitors in vivo. J Virol (1999) 1.08
Viral gene expression patterns in human herpesvirus 6B-infected T cells. J Virol (2002) 1.05
Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner. J Virol (2004) 1.02
Human herpesvirus 6B induces cell cycle arrest concomitant with p53 phosphorylation and accumulation in T cells. J Virol (2005) 0.99
HHV-6 and seizures. Herpes (2005) 0.98
The EBV-encoded LMP1 protein inhibits p53-triggered apoptosis but not growth arrest. Oncogene (1995) 0.96
Stabilization of p53 in human cytomegalovirus-initiated cells is associated with sequestration of HDM2 and decreased p53 ubiquitination. J Biol Chem (2007) 0.95
Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion. J Virol (2005) 0.95
Human cytomegalovirus IE1-72 protein interacts with p53 and inhibits p53-dependent transactivation by a mechanism different from that of IE2-86 protein. J Virol (2009) 0.94
Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen. J Clin Virol (2009) 0.92
Productive human herpesvirus 6 infection causes aberrant accumulation of p53 and prevents apoptosis. J Gen Virol (2004) 0.89
Evidence that the human cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation. J Virol (2006) 0.87
The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfection. J Virol (2009) 0.87
Human herpesvirus 6B inhibits cell proliferation by a p53-independent pathway. J Clin Virol (2006) 0.85
Human herpesvirus 6B induces phosphorylation of p53 in its regulatory domain by a CK2- and p38-independent pathway. J Gen Virol (2008) 0.81
U20 is responsible for human herpesvirus 6B inhibition of tumor necrosis factor receptor-dependent signaling and apoptosis. J Virol (2012) 0.81
UV-induced interaction between p38 MAPK and p53 serves as a molecular switch in determining cell fate. FEBS Lett (2010) 0.80
Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner. J Gen Virol (2008) 0.80
Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41. PLoS One (2009) 0.80
IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication. Proc Natl Acad Sci U S A (2013) 1.69
Classification of HHV-6A and HHV-6B as distinct viruses. Arch Virol (2013) 1.33
Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway. Mol Cell Proteomics (2010) 1.22
Regulation of pro-inflammatory cytokines TNFα and IL24 by microRNA-203 in primary keratinocytes. Cytokine (2012) 1.14
Multiple sclerosis is linked to Epstein-Barr virus infection. Rev Med Virol (2006) 1.11
M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation. Proc Natl Acad Sci U S A (2013) 1.10
Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling. J Biol Chem (2008) 1.06
Viral gene expression patterns in human herpesvirus 6B-infected T cells. J Virol (2002) 1.05
Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells. Mol Ther (2011) 1.04
MDM2 chaperones the p53 tumor suppressor. J Biol Chem (2007) 1.04
Osteopontin enhances phagocytosis through a novel osteopontin receptor, the alphaXbeta2 integrin. J Immunol (2009) 1.04
Shielding of sleeping beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cells. Mol Ther (2008) 1.02
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain. EMBO Rep (2003) 1.01
Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1. J Mol Biol (2004) 1.00
Identification of multiple HPV types on spermatozoa from human sperm donors. PLoS One (2011) 1.00
Human herpesvirus 6B induces cell cycle arrest concomitant with p53 phosphorylation and accumulation in T cells. J Virol (2005) 0.99
Data-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistance. J Proteome Res (2011) 0.97
A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection. J Biol Chem (2008) 0.96
Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer. Int J Cancer (2011) 0.94
Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. BMC Genomics (2011) 0.94
Genomic insertion of lentiviral DNA circles directed by the yeast Flp recombinase. BMC Biotechnol (2008) 0.93
Integrase-defective lentiviral vectors--a stage for nonviral integration machineries. Curr Gene Ther (2011) 0.93
Human herpesvirus-6B induces expression of the human endogenous retrovirus K18-encoded superantigen. J Clin Virol (2009) 0.92
Complexities in human herpesvirus-6A and -6B binding to host cells. Virology (2006) 0.90
DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors. Nucleic Acids Res (2013) 0.89
Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway. Biochem J (2013) 0.87
An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis. J Proteome Res (2012) 0.87
Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. J Biol Chem (2007) 0.86
Human herpesvirus 6B inhibits cell proliferation by a p53-independent pathway. J Clin Virol (2006) 0.85
The impact of cHS4 insulators on DNA transposon vector mobilization and silencing in retinal pigment epithelium cells. PLoS One (2012) 0.85
Identification of an in vivo CD4+ T cell-mediated response to polymorphic membrane proteins of Chlamydia pneumoniae during experimental infection. FEMS Immunol Med Microbiol (2004) 0.85
Suppression of microRNAs by dual-targeting and clustered Tough Decoy inhibitors. RNA Biol (2013) 0.85
Adaptive evolution of a stress response protein. PLoS One (2007) 0.84
Mapping a noncovalent protein-peptide interface by top-down FTICR mass spectrometry using electron capture dissociation. J Am Soc Mass Spectrom (2011) 0.84
Altered frequency of T regulatory cells is associated with disability status in relapsing-remitting multiple sclerosis patients. J Neuroimmunol (2012) 0.83
Restriction of human herpesvirus 6B replication by p53. J Gen Virol (2008) 0.83
Concepts in MDM2 Signaling: Allosteric Regulation and Feedback Loops. Genes Cancer (2012) 0.83
Searching for the Holy Grail; protein-protein interaction analysis and modulation. EMBO Rep (2012) 0.83
Activated CD8+ T cells in secondary progressive MS secrete lymphotoxin. Neurology (2003) 0.82
Human herpesvirus-6A/B binds to spermatozoa acrosome and is the most prevalent herpesvirus in semen from sperm donors. PLoS One (2012) 0.82
Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells. PLoS One (2013) 0.82
U20 is responsible for human herpesvirus 6B inhibition of tumor necrosis factor receptor-dependent signaling and apoptosis. J Virol (2012) 0.81
Regulation of cytokines by small RNAs during skin inflammation. J Biomed Sci (2010) 0.81
Sensitive, specific, and quantitative FTICR mass spectrometry of combinatorial post-translational modifications in intact histone H4. Anal Chem (2008) 0.81
Lentiviral vectors for cutaneous RNA managing. Exp Dermatol (2012) 0.81
Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway. FEBS J (2010) 0.81
Technology insight: the application of proteomics in gastrointestinal disease. Nat Clin Pract Gastroenterol Hepatol (2007) 0.81
Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner. J Gen Virol (2008) 0.80
Strength of prior stimuli determines the magnitude of secondary responsiveness in CD8+ T cells. Cell Immunol (2002) 0.80
Direct Repeat 6 from human herpesvirus-6B encodes a nuclear protein that forms a complex with the viral DNA processivity factor p41. PLoS One (2009) 0.80
Epstein-Barr virus peptide presented by HLA-E is predominantly recognized by CD8(bright) cells in multiple sclerosis patients. PLoS One (2012) 0.80
Seminal shedding of human herpesviruses. Virol J (2013) 0.80
Sustained CD8+ T-cell immune response to a novel immunodominant HLA-B*0702-associated epitope derived from an Epstein-Barr virus helicase-primase-associated protein. J Med Virol (2004) 0.79
Efficient sleeping beauty DNA transposition from DNA minicircles. Mol Ther Nucleic Acids (2013) 0.79
Synergy between vitamin D(3) and Toll-like receptor agonists regulates human dendritic cell response during maturation. Clin Dev Immunol (2013) 0.79
A novel ataxia-telangiectasia mutated autoregulatory feedback mechanism in murine embryonic stem cells. J R Soc Interface (2009) 0.79
A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis. J Biol Chem (2007) 0.79
The DR6 protein from human herpesvirus-6B induces p53-independent cell cycle arrest in G2/M. Virology (2014) 0.79
An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing. FEBS J (2008) 0.78
The B1-cell subpopulation is diminished in patients with relapsing-remitting multiple sclerosis. J Neuroimmunol (2013) 0.78
Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization. Virology (2013) 0.78
A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues. BMC Biotechnol (2011) 0.77
Crohn's disease intestinal CD4+ T cells have impaired interleukin-10 production which is not restored by probiotic bacteria. Scand J Gastroenterol (2007) 0.77
A Sensitive Quantification of HHV-6B by Real-time PCR. Biol Proced Online (2002) 0.76
Induction of cell-cell fusion from without by human herpesvirus 6B. J Virol (2006) 0.76
An animal model to evaluate the function and regulation of the adaptively evolving stress protein SEP53 in oesophageal bile damage responses. Cell Stress Chaperones (2008) 0.75
Chek2ing out the p53 pathway: can Puma lead the way? Cell Cycle (2011) 0.75
A lentiviral vector-based genetic sensor system for comparative analysis of permeability and activity of vitamin D3 analogues in xenotransplanted human skin. Exp Dermatol (2013) 0.75
[Epstein-Barr virus and disseminated sclerosis: causative or secondary associations?]. Ugeskr Laeger (2002) 0.75