PubRank

Nathalie Rufer

Author PubWeight™ 70.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res 2004 3.59
2 Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients. J Clin Invest 2011 3.28
3 Immune activation and CD8+ T-cell differentiation towards senescence in HIV-1 infection. PLoS Biol 2004 3.20
4 Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest 2005 3.11
5 Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood 2002 2.88
6 The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat Immunol 2008 2.87
7 Four functionally distinct populations of human effector-memory CD8+ T lymphocytes. J Immunol 2007 2.59
8 Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization. PLoS One 2012 1.77
9 New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site. J Immunol 2006 1.74
10 Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proc Natl Acad Sci U S A 2008 1.59
11 Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev 2002 1.58
12 MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer. Immunity 2013 1.51
13 Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med 2002 1.44
14 Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function. J Immunol 2010 1.33
15 Human effector CD8+ T lymphocytes express TLR3 as a functional coreceptor. J Immunol 2006 1.28
16 Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors. J Immunol 2009 1.25
17 Selecting highly affine and well-expressed TCRs for gene therapy of melanoma. Blood 2007 1.25
18 Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness. J Biol Chem 2012 1.16
19 A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination. J Immunol 2006 1.13
20 Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. Cancer Res 2006 1.11
21 Monoclonal T-cell expansions in asymptomatic individuals and in patients with large granular leukemia consist of cytotoxic effector T cells expressing the activating CD94:NKG2C/E and NKD2D killer cell receptors. Blood 2002 1.11
22 Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients. J Immunol 2009 1.09
23 Identification of swiprosin 1 in human lymphocytes. Proteomics 2004 1.04
24 Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time. J Immunol 2009 1.01
25 Mechanisms that limit the in vitro proliferative potential of human CD8+ T lymphocytes. J Immunol 2005 1.01
26 SHP-1 phosphatase activity counteracts increased T cell receptor affinity. J Clin Invest 2013 1.00
27 Distinct mechanisms control human naive and antigen-experienced CD8+ T lymphocyte proliferation. J Immunol 2006 1.00
28 Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. Int J Cancer 2011 0.99
29 Dominant human CD8 T cell clonotypes persist simultaneously as memory and effector cells in memory phase. J Immunol 2009 0.98
30 In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration. J Immunol 2007 0.97
31 Assessing ageing of individual T lymphocytes: mission impossible? Mech Ageing Dev 2007 0.95
32 Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues. Proc Natl Acad Sci U S A 2008 0.94
33 Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts. Cancer Res 2009 0.93
34 Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo. Oncoimmunology 2012 0.92
35 Sensitive gene expression profiling of human T cell subsets reveals parallel post-thymic differentiation for CD4+ and CD8+ lineages. J Immunol 2007 0.92
36 IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells. J Immunol 2007 0.90
37 Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma. J Immunother 2007 0.88
38 TCRep 3D: an automated in silico approach to study the structural properties of TCR repertoires. PLoS One 2011 0.85
39 Deciphering the unusual HLA-A2/Melan-A/MART-1-specific TCR repertoire in humans. Eur J Immunol 2014 0.84
40 Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose. Cancer Immunol Immunother 2011 0.84
41 Impact of 3 different short-term chemotherapy regimens on lymphocyte-depletion and reconstitution in melanoma patients. J Immunother 2010 0.84
42 Mechanisms regulating the proliferative potential of human CD8+ T lymphocytes overexpressing telomerase. J Immunol 2006 0.82
43 Retrovirus-mediated gene transfer in polyclonal T cells results in lower apoptosis and enhanced ex vivo cell expansion of CMV-reactive CD8 T cells as compared with EBV-reactive CD8 T cells. Blood 2003 0.82
44 Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol 2004 0.82
45 Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor. Int Immunol 2008 0.81
46 Novel soluble HLA-A2/MELAN-A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma. Int J Cancer 2010 0.81
47 Simultaneous coexpression of memory-related and effector-related genes by individual human CD8 T cells depends on antigen specificity and differentiation. J Immunother 2012 0.80
48 Two specific populations of GABAergic neurons originating from the medial and the caudal ganglionic eminences aid in proper navigation of callosal axons. Dev Neurobiol 2013 0.80
49 A stepwise protocol to coat aAPC beads prevents out-competition of anti-CD3 mAb and consequent experimental artefacts. J Immunol Methods 2012 0.80
50 Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes. Proc Natl Acad Sci U S A 2011 0.80
51 Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide. Eur J Immunol 2006 0.79
52 Profile of a serial killer: cellular and molecular approaches to study individual cytotoxic T-cells following therapeutic vaccination. J Biomed Biotechnol 2010 0.79
53 PPARgamma but not PPARalpha ligands are potent repressors of major histocompatibility complex class II induction in atheroma-associated cells. Circ Res 2002 0.78
54 An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain. Cancer Immun 2008 0.77
55 Molecular insights for optimizing T cell receptor specificity against cancer. Front Immunol 2013 0.77
56 Persistence of EBV antigen-specific CD8 T cell clonotypes during homeostatic immune reconstitution in cancer patients. PLoS One 2013 0.76
57 Proteomic and transcriptomic analysis of human CD8(+) T lymphocytes over-expressing telomerase. Proteomics Clin Appl 2007 0.75
58 Methods for human CD8(+) T lymphocyte proteome analysis. Methods Mol Biol 2008 0.75
59 [Publications of third year medical students after their community-based internships]. Rev Med Suisse 2010 0.75
60 Impact of orthologous melan-A peptide immunizations on the anti-self melan-A/HLA-A2 T cell cross-reactivity. J Immunol 2006 0.75