Published in PLoS Biol on April 16, 2013
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The gene for slow Wallerian degeneration (Wld(s)) is also protective against vincristine neuropathy. Neurobiol Dis (2001) 1.07
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The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model. Eur J Neurosci (2008) 1.43
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A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses. Eur J Neurosci (2005) 1.39
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Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies. Brain (2008) 1.26
Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo. J Neurosci (2010) 1.22
The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells. Hum Mol Genet (2006) 1.14
The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Mol Biol Cell (2005) 1.13
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Rescue of peripheral and CNS axon defects in mice lacking NMNAT2. J Neurosci (2013) 1.07
Neurites undergoing Wallerian degeneration show an apoptotic-like process with Annexin V positive staining and loss of mitochondrial membrane potential. Neurosci Res (2003) 1.04
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Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouse. Gene (2002) 0.87
Deletions within its subcellular targeting domain enhance the axon protective capacity of Nmnat2 in vivo. Sci Rep (2013) 0.87
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The axon-protective WLD(S) protein partially rescues mitochondrial respiration and glycolysis after axonal injury. J Mol Neurosci (2014) 0.79
MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS One (2013) 0.79
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Kif1Bbeta isoform is enriched in motor neurons but does not change in a mouse model of amyotrophic lateral sclerosis. J Neurosci Res (2003) 0.75