Published in Cell Death Differ on October 17, 2014
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Some reminiscences on studies of age-dependent and activity-dependent degeneration of sensory and motor endings in mammalian skeletal muscle. J Anat (2015) 0.75
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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science (2004) 7.29
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Axonal self-destruction and neurodegeneration. Science (2002) 4.30
The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron (2006) 4.13
Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene. Nat Neurosci (2001) 4.10
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Axonal degeneration is mediated by the mitochondrial permeability transition pore. J Neurosci (2011) 1.67
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The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein. PLoS Biol (2012) 1.60
The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Mol Cell Biol (2009) 1.60
WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering. Curr Biol (2012) 1.55
Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice. J Cell Biol (2009) 1.53
Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway. Ann Neurol (2011) 1.46
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Progressive abnormalities in skeletal muscle and neuromuscular junctions of transgenic mice expressing the Huntington's disease mutation. Eur J Neurosci (2004) 1.45
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Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning. Development (2010) 1.20
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The gene for slow Wallerian degeneration (Wld(s)) is also protective against vincristine neuropathy. Neurobiol Dis (2001) 1.07
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A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration. J Neurosci (2012) 1.05
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Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2. PLoS Biol (2013) 1.03
Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) regulates axon integrity in the mouse embryo. PLoS One (2012) 1.02
Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria. Hum Mol Genet (2013) 1.01
Local translation of ATP synthase subunit 9 mRNA alters ATP levels and the production of ROS in the axon. Mol Cell Neurosci (2011) 1.01
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Characterization of NAD uptake in mammalian cells. J Biol Chem (2008) 0.97
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Developmentally regulated impediments to skin reinnervation by injured peripheral sensory axon terminals. Curr Biol (2009) 0.96
Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo. Biochem Pharmacol (2009) 0.95
Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models. J Neurochem (2011) 0.95
Maintaining energy homeostasis is an essential component of Wld(S)-mediated axon protection. Neurobiol Dis (2013) 0.81
APC I1307K mutations and forkhead box gene (FOXO1A): another piece of an interesting correlation. Int J Biol Markers (2012) 0.77