Published in Xenobiotica on April 30, 2013
Self-microemulsifying drug-delivery system for improved oral bioavailability of 20(S)-25-methoxyl-dammarane-3β, 12β, 20-triol: preparation and evaluation. Int J Nanomedicine (2014) 0.82
In vitro metabolism of 20(R)-25-methoxyl-dammarane-3, 12, 20-triol from Panax notoginseng in human, monkey, dog, rat, and mouse liver microsomes. PLoS One (2014) 0.75
Improved oral bioavailability of 20(R)-25-methoxyl-dammarane-3β, 12β, 20-triol using nanoemulsion based on phospholipid complex: design, characterization, and in vivo pharmacokinetics in rats. Drug Des Devel Ther (2016) 0.75
Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. N Engl J Med (2014) 4.00
Delay in feedback repression by cryptochrome 1 is required for circadian clock function. Cell (2011) 2.71
In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. Cancer Chemother Pharmacol (2006) 2.33
To permute or not to permute. Bioinformatics (2006) 2.33
Detecting functional modules in the yeast protein-protein interaction network. Bioinformatics (2006) 2.20
Dandruff-associated Malassezia genomes reveal convergent and divergent virulence traits shared with plant and human fungal pathogens. Proc Natl Acad Sci U S A (2007) 2.18
Ultrafine particles affect experimental thrombosis in an in vivo hamster model. Am J Respir Crit Care Med (2002) 2.06
PAMAM nanoparticles promote acute lung injury by inducing autophagic cell death through the Akt-TSC2-mTOR signaling pathway. J Mol Cell Biol (2009) 2.00
Acoustic diode: rectification of acoustic energy flux in one-dimensional systems. Phys Rev Lett (2009) 1.99
Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations. Biol Psychiatry (2005) 1.71
Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine. Curr Med Chem (2009) 1.67
Default-mode network activity distinguishes amnestic type mild cognitive impairment from healthy aging: a combined structural and resting-state functional MRI study. Neurosci Lett (2008) 1.60
Deep whole-genome sequencing of 100 southeast Asian Malays. Am J Hum Genet (2013) 1.55
Obesity-related upregulation of monocyte chemotactic factors in adipocytes: involvement of nuclear factor-kappaB and c-Jun NH2-terminal kinase pathways. Diabetes (2008) 1.52
Current evaluation of the millennium phytomedicine--ginseng (I): etymology, pharmacognosy, phytochemistry, market and regulations. Curr Med Chem (2009) 1.50
MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway. Tumour Biol (2014) 1.49
Efficacy and safety of paliperidone palmitate in adult patients with acutely symptomatic schizophrenia: a randomized, double-blind, placebo-controlled, dose-response study. Int Clin Psychopharmacol (2010) 1.47
Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice. PLoS One (2011) 1.31
Experimental therapy of prostate cancer with novel natural product anti-cancer ginsenosides. Prostate (2008) 1.31
Abnormal neural activity in the patients with remitted geriatric depression: a resting-state functional magnetic resonance imaging study. J Affect Disord (2008) 1.29
Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus. J Alzheimers Dis (2008) 1.26
FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways. Obesity (Silver Spring) (2010) 1.24
Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles. J Agric Food Chem (2002) 1.19
Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts. J Biol Chem (2011) 1.18
Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice. J Neurosci Res (2009) 1.18
Carbon nanotubes conjugated to tumor lysate protein enhance the efficacy of an antitumor immunotherapy. Small (2008) 1.17
Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study. Neurobiol Aging (2010) 1.16
Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms. Mol Pharm (2007) 1.09
A comparative study of paliperidone palmitate and risperidone long-acting injectable therapy in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry (2011) 1.07
Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis. J Alzheimers Dis (2009) 1.07
Novel ginsenosides 25-OH-PPD and 25-OCH3-PPD as experimental therapy for pancreatic cancer: anticancer activity and mechanisms of action. Cancer Lett (2009) 1.07
Natural positive selection and north-south genetic diversity in East Asia. Eur J Hum Genet (2011) 1.06
New oligodendrocytes are generated after neonatal hypoxic-ischemic brain injury in rodents. Glia (2004) 1.05
MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice. J Clin Invest (2010) 1.05
Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro. PLoS One (2011) 1.05
Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes. J Clin Invest (2015) 1.05
A method for patterning multiple types of cells by using electrochemical desorption of self-assembled monolayers within microfluidic channels. Angew Chem Int Ed Engl (2007) 1.05
Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brain. Stroke (2002) 1.04
Identification of a novel cryptochrome differentiating domain required for feedback repression in circadian clock function. J Biol Chem (2012) 1.02
Thermotolerant Kluyveromyces marxianus and Saccharomyces cerevisiae strains representing potentials for bioethanol production from Jerusalem artichoke by consolidated bioprocessing. Appl Microbiol Biotechnol (2012) 1.02
Evaluation of the flocculation performance of carboxymethyl chitosan-graft-polyacrylamide, a novel amphoteric chemically bonded composite flocculant. Water Res (2011) 1.01
Breast cancer resistance protein (BCRP) and sulfotransferases contribute significantly to the disposition of genistein in mouse intestine. AAPS J (2010) 1.01
Anti-lung cancer effects of novel ginsenoside 25-OCH(3)-PPD. Lung Cancer (2009) 1.00
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands. Cell Res (2013) 1.00
Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC-MS/MS method: Application to an oral bioavailability study of genistein in mice. J Pharm Biomed Anal (2010) 0.99
Manifold regularized discriminative nonnegative matrix factorization with fast gradient descent. IEEE Trans Image Process (2011) 0.99
Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling. Neuron (2013) 0.97
Low-cost vibration sensor based on dual fiber Bragg gratings and light intensity measurement. Appl Opt (2013) 0.96
A stretching device for imaging real-time molecular dynamics of live cells adhering to elastic membranes on inverted microscopes during the entire process of the stretch. Integr Biol (Camb) (2010) 0.96
Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res (2009) 0.95
Short-term tropisetron treatment and cognitive and P50 auditory gating deficits in schizophrenia. Am J Psychiatry (2012) 0.95
Passage number is a major contributor to genomic structural variations in mouse iPSCs. Stem Cells (2014) 0.94
Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells. Nanoscale (2010) 0.94
Speciation of arsenic trioxide penetrates into cerebrospinal fluid in patients with acute promyelocytic leukemia. Leuk Res (2009) 0.94
HPLC determination and pharmacokinetics of sustained-release bupropion tablets in dogs. J Pharm Biomed Anal (2003) 0.94
Low serum BDNF may indicate the development of PSD in patients with acute ischemic stroke. Int J Geriatr Psychiatry (2010) 0.93
Fluoxetine attenuates the inhibitory effect of glucocorticoid hormones on neurogenesis in vitro via a two-pore domain potassium channel, TREK-1. Psychopharmacology (Berl) (2010) 0.93
The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes. Toxicol Sci (2010) 0.93
Repeated triamcinolone acetonide injection in the treatment of upper-lid retraction in patients with thyroid-associated ophthalmopathy. Can J Ophthalmol (2012) 0.93
Obesity modulates the expression of haptoglobin in the white adipose tissue via TNFalpha. J Cell Physiol (2002) 0.92
Iron(II)-catalyzed intramolecular olefin aminofluorination. Org Lett (2014) 0.92
Online nonnegative matrix factorization with robust stochastic approximation. IEEE Trans Neural Netw Learn Syst (2012) 0.92
Determination of 25-OH-PPD in rat plasma by high-performance liquid chromatography-mass spectrometry and its application in rat pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.91
Constitutive activation of IKKβ in adipose tissue prevents diet-induced obesity in mice. Endocrinology (2011) 0.91
Hepatic ERK activity plays a role in energy metabolism. Mol Cell Endocrinol (2013) 0.91
Effect of antioxidants on apoptosis induced by influenza virus infection: inhibition of viral gene replication and transcription with pyrrolidine dithiocarbamate. Antiviral Res (2002) 0.91
Validity of methods to predict the respiratory sensitizing potential of chemicals: A study with a piperidinyl chlorotriazine derivative that caused an outbreak of occupational asthma. Toxicol Sci (2003) 0.90
Immune responses of BALB/c mice to subcutaneously injected multi-walled carbon nanotubes. Nanotoxicology (2010) 0.90
Human adipose dynamics and metabolic health. Ann N Y Acad Sci (2013) 0.90
Formulation and in vitro/in vivo correlation of a drug-in-adhesive transdermal patch containing azasetron. J Pharm Sci (2012) 0.90
Structure-activity relationship and substrate-dependent phenomena in effects of ginsenosides on activities of drug-metabolizing P450 enzymes. PLoS One (2008) 0.90
Analysis of orientations of collagen fibers by novel fiber-tracking software. Microsc Microanal (2003) 0.90
A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations. Eur J Hum Genet (2011) 0.89
Development and evaluation of new sustained-release floating microspheres. Int J Pharm (2008) 0.89
Super-paramagnetic responsive nanofibrous scaffolds under static magnetic field enhance osteogenesis for bone repair in vivo. Sci Rep (2013) 0.89
Diabetes-impaired wound healing and altered macrophage activation: a possible pathophysiologic correlation. Wound Repair Regen (2012) 0.89
Grafting of zwitterion from cellulose membranes via ATRP for improving blood compatibility. Biomacromolecules (2009) 0.89
Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system. Int J Pharm (2010) 0.89
Multi-walled carbon nanotubes suppress potassium channel activities in PC12 cells. Nanotechnology (2009) 0.89
Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Hum Genet (2012) 0.89
Ginkgolide B produced endophytic fungus (Fusarium oxysporum) isolated from Ginkgo biloba. Fitoterapia (2012) 0.88
The internalization pathway, metabolic fate and biological effect of superparamagnetic iron oxide nanoparticles in the macrophage-like RAW264.7 cell. Sci China Life Sci (2011) 0.88
Suppression of CUGBP1 inhibits growth of hepatocellular carcinoma cells. Clin Invest Med (2014) 0.88
Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes. Toxicol Appl Pharmacol (2011) 0.88
The serum interleukin-18 is a potential marker for development of post-stroke depression. Neurol Res (2010) 0.88
Analysis of clinicopathological features and prognostic factors of desmoplastic small round cell tumor. Pathol Oncol Res (2013) 0.88
Multiwalled carbon nanotubes interact with macrophages and influence tumor progression and metastasis. Theranostics (2012) 0.88
Using single-walled carbon nanotubes nonwoven films as scaffolds to enhance long-term cell proliferation in vitro. J Biomed Mater Res A (2006) 0.87
Mapping MKP-3/FOXO1 interaction and evaluating the effect on gluconeogenesis. PLoS One (2012) 0.87
Non-negative patch alignment framework. IEEE Trans Neural Netw (2011) 0.87
Purification and characterization of a novel and unique ginsenoside Rg1-hydrolyzing β-D-glucosidase from Penicillium sclerotiorum. Acta Biochim Biophys Sin (Shanghai) (2011) 0.87
Effects of single-walled carbon nanotubes on the functions of plasma proteins and potentials in vascular prostheses. Nanomedicine (2005) 0.87
MiR-335 functions as a tumor suppressor in pancreatic cancer by targeting OCT4. Tumour Biol (2014) 0.87
Trafficking of gold nanorods in breast cancer cells: uptake, lysosome maturation, and elimination. ACS Appl Mater Interfaces (2013) 0.87
Endosome-mediated retrograde axonal transport of P2X3 receptor signals in primary sensory neurons. Cell Res (2011) 0.86
Monitoring cell-autonomous circadian clock rhythms of gene expression using luciferase bioluminescence reporters. J Vis Exp (2012) 0.86
Anticancer activity of Panax notoginseng extract 20(S)-25-OCH3-PPD: Targetting beta-catenin signalling. Clin Exp Pharmacol Physiol (2009) 0.86
Effects of short interfering RNA-mediated gene silencing of SKA1 on proliferation of hepatocellular carcinoma cells. Scand J Gastroenterol (2013) 0.86