James Ellis

Author PubWeight™ 60.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell 2011 6.71
2 A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol 2011 3.60
3 A vertebrate Polycomb response element governs segmentation of the posterior hindbrain. Cell 2009 3.36
4 Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nat Methods 2009 2.51
5 MBNL proteins repress ES-cell-specific alternative splicing and reprogramming. Nature 2013 2.49
6 Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum Mol Genet 2011 1.87
7 Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nat Biotechnol 2012 1.73
8 Retroviral vector silencing during iPS cell induction: an epigenetic beacon that signals distinct pluripotent states. J Cell Biochem 2008 1.71
9 Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications. Mol Ther 2004 1.54
10 Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nat Rev Genet 2009 1.36
11 Large-scale field application of RNAi technology reducing Israeli acute paralysis virus disease in honey bees (Apis mellifera, Hymenoptera: Apidae). PLoS Pathog 2010 1.29
12 Constitutive heterochromatin reorganization during somatic cell reprogramming. EMBO J 2011 1.27
13 EOS lentiviral vector selection system for human induced pluripotent stem cells. Nat Protoc 2009 1.17
14 Retrovirus silencer blocking by the cHS4 insulator is CTCF independent. Nucleic Acids Res 2003 1.16
15 Nuclear matrix association of the human beta-globin locus utilizing a novel approach to quantitative real-time PCR. Nucleic Acids Res 2003 1.14
16 Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres. EMBO Rep 2012 1.12
17 MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PLoS One 2009 1.09
18 iPS cells to model CDKL5-related disorders. Eur J Hum Genet 2011 1.08
19 Comparing women of differing sexual orientations using population-based sampling. Women Health 2004 1.06
20 Can breast and cervical cancer screening visits be used to enhance colorectal cancer screening? J Am Coll Radiol 2004 1.06
21 Transgenic mouse overexpressing syntaxin-1A as a diabetes model. Diabetes 2005 1.05
22 Ataxia-telangiectasia mutated (ATM) deficiency decreases reprogramming efficiency and leads to genomic instability in iPS cells. Biochem Biophys Res Commun 2011 1.01
23 X-chromosome inactivation in rett syndrome human induced pluripotent stem cells. Front Psychiatry 2012 0.97
24 A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity. J Pharmacol Exp Ther 2004 0.95
25 eGFP reporter genes silence LCRbeta-globin transgene expression via CpG dinucleotides. Mol Ther 2005 0.94
26 'Multicopy multivalent' glycopolymer-stabilized gold nanoparticles as potential synthetic cancer vaccines. J Am Chem Soc 2013 0.94
27 Exploring self-management characteristics in youths with type 1 diabetes mellitus: does membership in a glycemic control category matter? Pediatr Diabetes 2010 0.93
28 Benefits of utilizing gene-modified iPSCs for clinical applications. Cell Stem Cell 2010 0.92
29 Modeling and rescue of the vascular phenotype of Williams-Beuren syndrome in patient induced pluripotent stem cells. Stem Cells Transl Med 2012 0.92
30 Beta-globin LCR and intron elements cooperate and direct spatial reorganization for gene therapy. PLoS Genet 2008 0.91
31 "Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells. Mamm Genome 2005 0.90
32 Reduced functional connectivity of prefrontal regions and amygdala within affect and working memory networks in pediatric bipolar disorder. Brain Connect 2012 0.88
33 A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther 2011 0.88
34 Kinetics and epigenetics of retroviral silencing in mouse embryonic stem cells defined by deletion of the D4Z4 element. Mol Ther 2013 0.86
35 Enhanced gene expression through temperature profile-induced variations in molecular architecture of thermoresponsive polymer vectors. J Gene Med 2007 0.86
36 Initiation of DNA replication at the human beta-globin 3' enhancer. Nucleic Acids Res 2005 0.84
37 Real-time fluorescence tracking of dynamic transgene variegation in stem cells. Mol Ther 2007 0.84
38 Deviation of islet autoreactivity to cryptic epitopes protects NOD mice from diabetes. Eur J Immunol 2003 0.84
39 Unexpected acceleration of type 1 diabetes by transgenic expression of B7-H1 in NOD mouse peri-islet glia. Diabetes 2010 0.83
40 Epigenetics of induced pluripotency, the seven-headed dragon. Stem Cell Res Ther 2010 0.83
41 Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells. Sci Rep 2013 0.82
42 Modeling complex neuropsychiatric disease with induced pluripotent stem cells. F1000 Biol Rep 2010 0.81
43 LCR-regulated transgene expression levels depend on the Oct-1 site in the AT-rich region of beta -globin intron-2. Blood 2002 0.81
44 Rapid transcriptional pulsing dynamics of high expressing retroviral transgenes in embryonic stem cells. PLoS One 2012 0.80
45 Treatment of acute silicoproteinosis by whole-lung lavage. Semin Cardiothorac Vasc Anesth 2013 0.78
46 The effect of a novel, dual function histamine H1 receptor antagonist/5-lipoxygenase enzyme inhibitor on in vivo dermal inflammation and extravasation. Eur J Pharmacol 2004 0.78
47 Personalized Medicine in the Genomics Era: highlights from an international symposium on childhood heart disease. Future Cardiol 2012 0.77
48 Excretory urography: trends in clinical use and diagnostic yield. Abdom Imaging 2009 0.75
49 Predictors of metabolic control at one year in a population of pediatric patients with type 2 diabetes mellitus: a retrospective study. J Pediatr Endocrinol Metab 2006 0.75
50 Detection of nitros(yl)ated metabolites of nitric oxide (NO) in vivo by gas-phase chemiluminescence assay. Curr Protoc Pharmacol 2006 0.75