Asthma-snapshot or motion picture?

PubWeight™: 0.76‹?›

🔗 View Article (PMC 3639421)

Published in Front Genet on April 30, 2013

Authors

Anabela G Berenguer1, Alexandra Rosa, António Brehm

Author Affiliations

1: Human Genetics Laboratory, University of Madeira Funchal, Portugal.

Articles cited by this

Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A (2005) 15.46

Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol (2007) 15.45

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet (1962) 13.72

Most rare missense alleles are deleterious in humans: implications for complex disease and association studies. Am J Hum Genet (2007) 10.92

Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science (2005) 10.02

Association study designs for complex diseases. Nat Rev Genet (2001) 8.91

Dissecting complex disease: the quest for the Philosopher's Stone? Int J Epidemiol (2006) 5.64

Asthma phenotypes: the evolution from clinical to molecular approaches. Nat Med (2012) 4.85

Evolution in health and medicine Sackler colloquium: Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci U S A (2009) 4.40

Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol (2008) 3.59

Childhood incident asthma and traffic-related air pollution at home and school. Environ Health Perspect (2010) 3.24

The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol (2010) 2.74

Functions of T cells in asthma: more than just T(H)2 cells. Nat Rev Immunol (2010) 2.62

Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol (2003) 2.59

Prenatal and passive smoke exposure and incidence of asthma and wheeze: systematic review and meta-analysis. Pediatrics (2012) 2.37

Environmental epigenetics and asthma: current concepts and call for studies. Am J Respir Crit Care Med (2008) 2.26

Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med (2010) 2.20

Assessing the reproducibility of asthma candidate gene associations, using genome-wide data. Am J Respir Crit Care Med (2009) 2.10

Population-specificity of human DNA methylation. Genome Biol (2012) 2.04

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions. J Exp Med (2009) 2.00

The regulation of allergy and asthma. Immunol Rev (2006) 1.86

IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma. J Allergy Clin Immunol (2006) 1.82

Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and IgE production in vivo. Toxicol Sci (2007) 1.73

Gene-environment interactions in asthma. J Allergy Clin Immunol (2009) 1.67

Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma. Eur Respir Rev (2010) 1.56

Obesity: evolution of a symptom of affluence. Neth J Med (2011) 1.52

Evolution and respiratory genetics. Eur Respir J (2006) 1.43

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma. Am J Respir Crit Care Med (1999) 1.39

Different antibody- and cytokine-mediated responses to Plasmodium falciparum parasite in two sympatric ethnic tribes living in Mali. Microbes Infect (2004) 1.36

Too clean, or not too clean: the hygiene hypothesis and home hygiene. Clin Exp Allergy (2006) 1.32

Allergic asthma: influence of genetic and environmental factors. J Biol Chem (2011) 1.30

The rising trends in asthma and allergic disease. Clin Exp Allergy (1998) 1.27

Antimalarial antibody levels and IL4 polymorphism in the Fulani of West Africa. Genes Immun (2001) 1.25

Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing. Eur Respir J (1989) 1.24

Association between air pollution and asthma admission among children in Hong Kong. Clin Exp Allergy (2006) 1.22

Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children. J Allergy Clin Immunol (2011) 1.21

DNA methylation and the expression of IL-4 and IFN-gamma promoter genes in patients with bronchial asthma. J Clin Immunol (2007) 1.20

Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations? PLoS Genet (2011) 1.17

Case-control admixture mapping in Latino populations enriches for known asthma-associated genes. J Allergy Clin Immunol (2012) 1.17

Coming back to a missing immune deviation as the main explanatory mechanism for the hygiene hypothesis. J Allergy Clin Immunol (2007) 1.11

Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children. Environ Res (2011) 1.07

In utero life and epigenetic predisposition for disease. Adv Genet (2010) 1.06

The hygiene hypothesis in allergy and asthma: an update. Curr Opin Allergy Clin Immunol (2013) 1.05

Epigenetic mechanisms and models in the origins of asthma. Curr Opin Allergy Clin Immunol (2013) 1.02

Epidemiology: Racing against the flu. Nature (2011) 0.99

Outdoor air pollution and asthma in children. J Asthma (2011) 0.98

Clinical implications of airway hyperresponsiveness in COPD. Int J Chron Obstruct Pulmon Dis (2006) 0.98

Association between C-589T polymorphisms of interleukin-4 gene promoter and asthma: a meta-analysis. Respir Med (2008) 0.97

An understanding of the genetic basis of asthma. Indian J Med Res (2011) 0.94

What are genes "for" or where are traits "from"? What is the question? Bioessays (2009) 0.94

Relative levels of IL4 and IFN-gamma in complicated malaria: association with IL4 polymorphism and peripheral parasitemia. Acta Trop (2007) 0.91

Epigenetics of asthma. Biochim Biophys Acta (2011) 0.91

Asthma: a simple concept but in reality a complex disease. Eur J Clin Invest (2011) 0.89

Recent advances in the epidemiologic investigation of risk factors for asthma: a review of the 2011 literature. Curr Allergy Asthma Rep (2012) 0.88

Asthma and Rhinitis in South America: How Different They are From Other Parts of the World. Allergy Asthma Immunol Res (2011) 0.86

Association between the IL-4 promoter polymorphisms and asthma or severity of hyperresponsiveness in Taiwanese. Respirology (2007) 0.85

DNA methylation in the Neuropeptide S Receptor 1 (NPSR1) promoter in relation to asthma and environmental factors. PLoS One (2013) 0.84

Allelic polymorphisms in the interleukin-4 promoter regions and their association with bronchial asthma among the Russian population. Int Arch Allergy Immunol (2006) 0.84

Genetic variation of ITGB3 is associated with asthma in Chinese Han children. PLoS One (2013) 0.81

The -590C/TIL4 single-nucleotide polymorphism as a genetic factor of atopic allergy. Int J Mol Epidemiol Genet (2009) 0.81

Connecting the dots: molecular and epigenetic mechanisms in type 2 diabetes. Curr Diabetes Rev (2010) 0.80

Bronchial Hyperresponsiveness to Methacholine and AMP in Children With Atopic Asthma. Allergy Asthma Immunol Res (2012) 0.79

(Too) great expectations: the challenges in replicating asthma disease genes. Am J Respir Crit Care Med (2009) 0.79

[A study on the relationship between interleukin-4 promoter polymorphism and asthma in a Xinjiang Uyger population]. Zhonghua Jie He He Hu Xi Za Zhi (2004) 0.78

Distribution of polymorphisms IL4-590 C/T and IL4 RP2 in the human populations of Madeira, Azores, Portugal, Cape Verde and Guinea-Bissau. Int J Mol Epidemiol Genet (2012) 0.76

Articles by these authors

Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in europe. Am J Hum Genet (2004) 2.32

Ethiopian mitochondrial DNA heritage: tracking gene flow across and around the gate of tears. Am J Hum Genet (2004) 1.84

Africans in Yorkshire? The deepest-rooting clade of the Y phylogeny within an English genealogy. Eur J Hum Genet (2007) 1.78

Toward male individualization with rapidly mutating y-chromosomal short tandem repeats. Hum Mutat (2014) 1.53

Convergence of miRNA expression profiling, α-synuclein interacton and GWAS in Parkinson's disease. PLoS One (2011) 1.19

Y-chromosomal diversity in the population of Guinea-Bissau: a multiethnic perspective. BMC Evol Biol (2007) 1.16

Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas. Hum Mutat (2004) 1.14

MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region. Ann Hum Genet (2004) 1.03

RTTN mutations link primary cilia function to organization of the human cerebral cortex. Am J Hum Genet (2012) 1.01

Y-chromosome lineages from Portugal, Madeira and Açores record elements of Sephardim and Berber ancestry. Ann Hum Genet (2005) 0.99

Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease. Arthritis Rheum (2012) 0.97

Y-chromosome lineages in Cabo Verde Islands witness the diverse geographic origin of its first male settlers. Hum Genet (2003) 0.95

Evaluation of two methods for computational HLA haplotypes inference using a real dataset. BMC Bioinformatics (2008) 0.92

Genetic profile of a multi-ethnic population from Guiné-Bissau (west African coast) using the new PowerPlex 16 System kit. Forensic Sci Int (2002) 0.86

RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population. BMC Cardiovasc Disord (2008) 0.86

Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: the A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal). Thromb Res (2008) 0.83

Genetic profile of the Madeira Archipelago population using the new PowerPlex16 System kit. Forensic Sci Int (2002) 0.81

Alpha-1-antitrypsin deficiency in Madeira (Portugal): the highest prevalence in the world. Respir Med (2009) 0.81

Population data on 11 Y-chromosome STRs from Guiné-Bissau. Forensic Sci Int (2006) 0.81

Prevalence of H63D, S65C, and C282Y hereditary hemochromatosis gene variants in Madeira Island (Portugal). Ann Hematol (2010) 0.81

Genetic profile of the Açores Archipelago population using the new PowerPlex 16 system kit. Forensic Sci Int (2002) 0.80

Gene-gene interaction affects coronary artery disease risk. Rev Port Cardiol (2009) 0.80

DAZ gene copies: evidence of Y chromosome evolution. Mol Hum Reprod (2006) 0.79

Independent association of the variant rs1333049 at the 9p21 locus and coronary heart disease. Rev Port Cardiol (2011) 0.79

Human paraoxonase gene polymorphisms and coronary artery disease risk. Rev Port Cardiol (2008) 0.79

Alpha-1-antitrypsin deficiency in the Cape Verde islands (Northwest Africa): High prevalence in a sub-Saharan population. Respir Med (2010) 0.79

Y-chromosome lineages in São Tomé e Príncipe islands: evidence of European influence. Am J Hum Biol (2007) 0.78

HLA polymorphisms in Cabo Verde and Guiné-Bissau inferred from sequence-based typing. Hum Immunol (2005) 0.78

Functional evaluation of neural stem cell differentiation by single cell calcium imaging. Curr Stem Cell Res Ther (2011) 0.77

Interaction of paraoxonase-192 polymorphism with low HDL-cholesterol in coronary artery disease risk. Rev Port Cardiol (2010) 0.77

Y-chromosomal STRs in two populations from Israel and the Palestinian Authority Area: Christian and Muslim Arabs. Forensic Sci Int Genet (2010) 0.77

Phylogeography of Mabuya maculilabris (Reptilia) from São Tomé Island (Gulf of Guinea) inferred from mtDNA sequences. Mol Phylogenet Evol (2005) 0.76

HLA genes in Madeira Island (Portugal) inferred from sequence-based typing: footprints from different origins. Mol Immunol (2005) 0.76

Population data of five STRs in three regions from Portugal. Forensic Sci Int (2002) 0.75

Discrepancies in HLA typing by PCR-SSOP and SBT techniques: a case study. Hum Biol (2007) 0.75

Relationships of Afroablepharus Greer, 1974 skinks from the Gulf of Guinea islands based on mitochondrial and nuclear DNA: patterns of colonization and comments on taxonomy. Mol Phylogenet Evol (2007) 0.75

Y-chromosome STR haplotypes in the Açores Archipelago (Portugal). Forensic Sci Int (2003) 0.75

Identification of endangered petrel species from poor quality feather debris using cytochrome b sequences. Forensic Sci Int (2007) 0.75

Association of mitochondrial polymorphism m.709G>A with Behçet's disease. Ann Rheum Dis (2011) 0.75

Frequency of the CCR5-delta32 mutation in the Atlantic island populations of Madeira, the Azores, Cabo Verde, and São Tomé e Príncipe. Hum Biol (2006) 0.75

Relationship between ADD1 Gly460Trp gene polymorphism and essential hypertension in Madeira Island. Medicine (Baltimore) (2017) 0.75