Published in Am J Respir Cell Mol Biol on October 01, 2013
Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study. Respir Res (2014) 1.09
Aging mesenchymal stem cells fail to protect because of impaired migration and antiinflammatory response. Am J Respir Crit Care Med (2014) 0.97
Recent advances in epithelium-derived cytokines (IL-33, IL-25, and thymic stromal lymphopoietin) and allergic inflammation. Curr Opin Allergy Clin Immunol (2015) 0.93
Pathophysiology and biomarkers of acute respiratory distress syndrome. J Intensive Care (2014) 0.92
Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response. Mediators Inflamm (2016) 0.78
Human mesenchymal stem cells resolve airway inflammation, hyperreactivity, and histopathology in a mouse model of occupational asthma. Stem Cells Dev (2014) 0.78
Role of the IL-33-ST2 axis in sepsis. Mil Med Res (2017) 0.76
Stem/progenitor cells in endogenous repairing responses: new toolbox for the treatment of acute lung injury. J Transl Med (2016) 0.75
Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome. F1000Res (2016) 0.75
IL-33 Signaling in Lung Injury. Transl Perioper Pain Med (2016) 0.75
Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats. Mol Med Rep (2016) 0.75
Mesenchymal stromal cells for treatment of the acute respiratory distress syndrome: The beginning of the story. J Intensive Care Soc (2015) 0.75
Cyclic stretch induced IL-33 production through HMGB1/TLR-4 signaling pathway in murine respiratory epithelial cells. PLoS One (2017) 0.75
International study of the prevalence and outcomes of infection in intensive care units. JAMA (2009) 11.57
Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia. Chest (2003) 5.64
DALI: defining antibiotic levels in intensive care unit patients: are current β-lactam antibiotic doses sufficient for critically ill patients? Clin Infect Dis (2014) 3.99
An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis (2003) 3.93
Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa. Crit Care Med (2002) 3.63
A multicenter study of septic shock due to candidemia: outcomes and predictors of mortality. Intensive Care Med (2014) 3.56
Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia. Am J Respir Crit Care Med (2004) 3.49
Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza. Crit Care (2009) 3.48
Microbial aetiology of healthcare associated pneumonia in Spain: a prospective, multicentre, case-control study. Thorax (2013) 3.05
Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy. Crit Care Med (2007) 2.94
Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients*. Crit Care Med (2014) 2.86
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation. J Biol Chem (2008) 2.77
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Hum Gene Ther (2007) 2.64
Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock. Crit Care Med (2007) 2.44
Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy: high flow nasal cannula in heart failure. J Crit Care (2013) 2.43
High-flow oxygen therapy in acute respiratory failure. Respir Care (2010) 2.40
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J (2009) 2.37
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. J Neurosci (2009) 2.36
The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons. Science (2009) 2.35
Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival. Chest (2003) 2.31
Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin. Intensive Care Med (2004) 2.30
Management of community-acquired pneumonia in adults. Am J Respir Crit Care Med (2010) 2.29
Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia. Crit Care Med (2007) 2.22
Clinical impact of pneumonia caused by Acinetobacter baumannii in intubated patients: a matched cohort study. Crit Care Med (2003) 2.13
A worldwide perspective of atypical pathogens in community-acquired pneumonia. Am J Respir Crit Care Med (2007) 2.08
A clinical algorithm to diagnose invasive pulmonary aspergillosis in critically ill patients. Am J Respir Crit Care Med (2012) 2.06
Multicenter, double-blind, placebo-controlled study of the use of filgrastim in patients hospitalized with pneumonia and severe sepsis. Crit Care Med (2003) 1.98
Acinetobacter baumannii: a threat for the ICU? Intensive Care Med (2003) 1.93
Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia. J Infect Dis (2003) 1.90
Pseudomonas aeruginosa virulence and therapy: evolving translational strategies. Crit Care Med (2009) 1.89
A randomized trial of dental brushing for preventing ventilator-associated pneumonia. Chest (2009) 1.87
Distribution of PINK1 and LRRK2 in rat and mouse brain. J Neurochem (2006) 1.85
Drug-resistant pneumococcal pneumonia: clinical relevance and related factors. Clin Infect Dis (2004) 1.85
New issues and controversies in the prevention of ventilator-associated pneumonia. Am J Respir Crit Care Med (2010) 1.84
Increased mortality associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in the intensive care unit: results from the EPIC II study. Int J Antimicrob Agents (2011) 1.80
Global prospective epidemiologic and surveillance study of ventilator-associated pneumonia due to Pseudomonas aeruginosa. Crit Care Med (2014) 1.77
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites. Biochem Biophys Res Commun (2009) 1.67
Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia. Crit Care Med (2007) 1.66
Host adaptive immunity deficiency in severe pandemic influenza. Crit Care (2010) 1.64
Nursing adherence with evidence-based guidelines for preventing ventilator-associated pneumonia. Crit Care Med (2003) 1.61
Severe 2009 A/H1N1v influenza in pregnant women in Spain. Crit Care Med (2011) 1.61
Clinical resolution in patients with suspicion of ventilator-associated pneumonia: a cohort study comparing patients with and without acute respiratory distress syndrome. Crit Care Med (2005) 1.60
Prospective observational study of bacteremic pneumococcal pneumonia: Effect of discordant therapy on mortality. Crit Care Med (2004) 1.58
CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling. Blood (2008) 1.56
Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. Hum Gene Ther (2009) 1.54
A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality. Intensive Care Med (2015) 1.54
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci U S A (2014) 1.53
Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia. Crit Care Med (2013) 1.50
Centers for Disease Control and Prevention guidelines for preventing central venous catheter-related infection: results of a knowledge test among 3405 European intensive care nurses. Crit Care Med (2009) 1.48
Validation of predictors of adverse outcomes in hospital-acquired pneumonia in the ICU. Crit Care Med (2013) 1.48
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study. Intensive Care Med (2012) 1.47
Risk factors for respiratory failure in pneumococcal pneumonia: the importance of pneumococcal serotypes. Eur Respir J (2013) 1.45
Effect of high-flow nasal cannula and body position on end-expiratory lung volume: a cohort study using electrical impedance tomography. Respir Care (2013) 1.42
Comparison of lentiviral vector titration methods. BMC Biotechnol (2006) 1.42
Severity of illness assessment for managing community-acquired pneumonia. Intensive Care Med (2007) 1.42
Improving outcomes in elderly patients with community-acquired pneumonia by adhering to national guidelines: Community-Acquired Pneumonia Organization International cohort study results. Arch Intern Med (2009) 1.40
Late admission to the ICU in patients with community-acquired pneumonia is associated with higher mortality. Chest (2009) 1.40
The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clin Pharmacokinet (2011) 1.39
Upscaling of lentiviral vector production by tangential flow filtration. J Gene Med (2005) 1.38
Enteric absorption and pharmacokinetics of oseltamivir in critically ill patients with pandemic (H1N1) influenza. CMAJ (2010) 1.33
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant. J Neurochem (2011) 1.33
Hybrid pathogenicity island PAGI-5 contributes to the highly virulent phenotype of a Pseudomonas aeruginosa isolate in mammals. J Bacteriol (2008) 1.33
Automated quantitative gait analysis in animal models of movement disorders. BMC Neurosci (2010) 1.31
C-reactive protein correlates with bacterial load and appropriate antibiotic therapy in suspected ventilator-associated pneumonia. Crit Care Med (2008) 1.25
Interleukin-6 is a potential biomarker for severe pandemic H1N1 influenza A infection. PLoS One (2012) 1.23
Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units. Crit Care Med (2009) 1.21
LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding. PLoS One (2011) 1.19
Patterns of colonization by Pseudomonas aeruginosa in intubated patients: a 3-year prospective study of 1,607 isolates using pulsed-field gel electrophoresis with implications for prevention of ventilator-associated pneumonia. Intensive Care Med (2004) 1.19
C-reactive protein used as an early indicator of infection in patients with systemic inflammatory response syndrome. Intensive Care Med (2004) 1.17
Better outcomes through continuous infusion of time-dependent antibiotics to critically ill patients? Curr Opin Crit Care (2008) 1.17
Impact of obesity in patients infected with 2009 influenza A(H1N1). Chest (2010) 1.13
Ventilator-associated pneumonia: issues related to the artificial airway. Respir Care (2005) 1.13
Genomic islands of Pseudomonas aeruginosa. FEMS Microbiol Lett (2008) 1.12
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein. Hum Mol Genet (2012) 1.11
Noninvasive monitoring of long-term lentiviral vector-mediated gene expression in rodent brain with bioluminescence imaging. Mol Ther (2006) 1.11
Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance. J Cell Sci (2011) 1.11
Lentiviral vector-mediated delivery of short hairpin RNA results in persistent knockdown of gene expression in mouse brain. Hum Gene Ther (2003) 1.11
Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study. Crit Care (2011) 1.10
Quantitative evaluation of MRI-based tracking of ferritin-labeled endogenous neural stem cell progeny in rodent brain. Neuroimage (2012) 1.10
Construction and evaluation of multitracer small-animal PET probabilistic atlases for voxel-based functional mapping of the rat brain. J Nucl Med (2006) 1.10
Epidemiology, species distribution, antifungal susceptibility, and outcome of candidemia across five sites in Italy and Spain. J Clin Microbiol (2013) 1.10
The ventilator-associated pneumonia PIRO score: a tool for predicting ICU mortality and health-care resources use in ventilator-associated pneumonia. Chest (2008) 1.09
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. PLoS One (2012) 1.09
Microclimate and human factors in the divergent ecology of Aedes aegypti along the Arizona, U.S./Sonora, MX border. Ecohealth (2010) 1.09
Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors. Intensive Care Med (2013) 1.09
Treatment options for 2009 H1N1 influenza: evaluation of the published evidence. Int J Antimicrob Agents (2010) 1.07
Legionnaires' disease: a rational approach to therapy. J Antimicrob Chemother (2003) 1.06
Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1. FASEB J (2009) 1.04
Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization. Chest (2008) 1.04
MRI visualization of endogenous neural progenitor cell migration along the RMS in the adult mouse brain: validation of various MPIO labeling strategies. Neuroimage (2009) 1.04
Impact of diversity of antibiotic use on the development of antimicrobial resistance. J Antimicrob Chemother (2006) 1.03
Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia. Chest (2008) 1.03
Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A. J Antimicrob Chemother (2011) 1.02
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease. EMBO J (2013) 1.02
Flucloxacillin dosing in critically ill patients with hypoalbuminaemia: special emphasis on unbound pharmacokinetics. J Antimicrob Chemother (2010) 1.02
High-flow nasal therapy in adults with severe acute respiratory infection: a cohort study in patients with 2009 influenza A/H1N1v. J Crit Care (2012) 1.01
Ventilator-associated pneumonia caused by ESKAPE organisms: cause, clinical features, and management. Curr Opin Pulm Med (2012) 1.01
Management of ventilator-associated pneumonia caused by multiresistant bacteria. Curr Opin Crit Care (2007) 1.00