Understanding increased mortality in Clostridium difficile-infected older adults.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMC 3719887)

Published in Clin Infect Dis on May 08, 2013

Authors

Seth T Walk, Dejan Micic, Andrzej T Galecki, Vincent B Young, David M Aronoff

Articles by these authors

Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun (2009) 7.48

Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea. J Infect Dis (2008) 6.21

Analysis of the lung microbiome in the "healthy" smoker and in COPD. PLoS One (2011) 4.65

Clostridium difficile ribotype does not predict severe infection. Clin Infect Dis (2012) 4.34

Comparison of the respiratory microbiome in healthy nonsmokers and smokers. Am J Respir Crit Care Med (2013) 3.65

Decade-long bacterial community dynamics in cystic fibrosis airways. Proc Natl Acad Sci U S A (2012) 3.43

From structure to function: the ecology of host-associated microbial communities. Microbiol Mol Biol Rev (2010) 2.42

The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile Infection. Gut Microbes (2011) 2.37

Genome sequencing of environmental Escherichia coli expands understanding of the ecology and speciation of the model bacterial species. Proc Natl Acad Sci U S A (2011) 2.21

High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up. Diabetes Care (2010) 2.12

Changes in cystic fibrosis airway microbiota at pulmonary exacerbation. Ann Am Thorac Soc (2013) 2.05

Evolutionary genetics of a new pathogenic Escherichia species: Escherichia albertii and related Shigella boydii strains. J Bacteriol (2005) 2.01

Cyclic AMP: master regulator of innate immune cell function. Am J Respir Cell Mol Biol (2008) 2.00

Significance of the microbiome in obstructive lung disease. Thorax (2012) 1.97

Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. Aging Cell (2006) 1.89

Alteration of the murine gut microbiota during infection with the parasitic helminth Heligmosomoides polygyrus. Inflamm Bowel Dis (2010) 1.85

Suppression of Clostridium difficile in the gastrointestinal tracts of germfree mice inoculated with a murine isolate from the family Lachnospiraceae. Infect Immun (2012) 1.79

Fever and hypothermia in systemic inflammation: recent discoveries and revisions. Front Biosci (2005) 1.75

Interaction between the intestinal microbiota and host in Clostridium difficile colonization resistance. Trends Microbiol (2012) 1.70

Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis (2003) 1.69

Colonization of the cecal mucosa by Helicobacter hepaticus impacts the diversity of the indigenous microbiota. Infect Immun (2005) 1.67

Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling. Am J Physiol Lung Cell Mol Physiol (2006) 1.66

Widespread colonization of the lung by Tropheryma whipplei in HIV infection. Am J Respir Crit Care Med (2013) 1.66

Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase. Blood (2005) 1.62

Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Mol Endocrinol (2002) 1.61

Relationship between COMLEX and USMLE scores among osteopathic medical students who take both examinations. Teach Learn Med (2010) 1.60

The microbiome of the lung. Transl Res (2012) 1.59

Perturbation of the small intestine microbial ecology by streptomycin alters pathology in a Salmonella enterica serovar typhimurium murine model of infection. Infect Immun (2009) 1.59

Antibiotic administration alters the community structure of the gastrointestinal micobiota. Gut Microbes (2010) 1.57

Analysis of the upper respiratory tract microbiotas as the source of the lung and gastric microbiotas in healthy individuals. MBio (2015) 1.56

Critical role of prostaglandin E2 overproduction in impaired pulmonary host response following bone marrow transplantation. J Immunol (2006) 1.56

Depression, antidepressant medications, and risk of Clostridium difficile infection. BMC Med (2013) 1.54

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases. Proc Natl Acad Sci U S A (2002) 1.54

Prostaglandin E2 suppresses bacterial killing in alveolar macrophages by inhibiting NADPH oxidase. Am J Respir Cell Mol Biol (2007) 1.52

Stabilization of the murine gut microbiome following weaning. Gut Microbes (2012) 1.49

Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activity. Am J Respir Cell Mol Biol (2004) 1.47

Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis. Inflamm Bowel Dis (2010) 1.44

Fimbrial profiles predict virulence of uropathogenic Escherichia coli strains: contribution of ygi and yad fimbriae. Infect Immun (2011) 1.44

Impact of enhanced Staphylococcus DNA extraction on microbial community measures in cystic fibrosis sputum. PLoS One (2012) 1.40

Microbiome data distinguish patients with Clostridium difficile infection and non-C. difficile-associated diarrhea from healthy controls. MBio (2014) 1.40

Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy. Infect Immun (2012) 1.36

The gut microbiome in health and in disease. Curr Opin Gastroenterol (2015) 1.33

Cefoperazone-treated mice as an experimental platform to assess differential virulence of Clostridium difficile strains. Gut Microbes (2011) 1.29

Role of granulocyte macrophage colony-stimulating factor during gram-negative lung infection with Pseudomonas aeruginosa. Am J Respir Cell Mol Biol (2006) 1.28

Application of a neutral community model to assess structuring of the human lung microbiome. MBio (2015) 1.25

Streptococcus intermedius causing infective endocarditis and abscesses: a report of three cases and review of the literature. BMC Infect Dis (2008) 1.23

Procalcitonin levels associate with severity of Clostridium difficile infection. PLoS One (2013) 1.22

Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae. Infect Immun (2009) 1.22

Escherichia albertii in wild and domestic birds. Emerg Infect Dis (2010) 1.22

Variation of the natural transformation frequency of Campylobacter jejuni in liquid shake culture. Microbiology (2003) 1.21

Pathogenesis of renal disease due to enterohemorrhagic Escherichia coli in germ-free mice. Infect Immun (2008) 1.20

Fibroblasts from long-lived bird species are resistant to multiple forms of stress. J Exp Biol (2011) 1.18

Necrotizing fasciitis: pathogenesis and treatment. Expert Rev Anti Infect Ther (2005) 1.18

A gene-targeted approach to investigate the intestinal butyrate-producing bacterial community. Microbiome (2013) 1.17

Modulation of host immune responses by the cytolethal distending toxin of Helicobacter hepaticus. Infect Immun (2006) 1.16

Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment. Proc Natl Acad Sci U S A (2009) 1.15

Alteration of the murine gastrointestinal microbiota by tigecycline leads to increased susceptibility to Clostridium difficile infection. Antimicrob Agents Chemother (2014) 1.14

The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates. Anaerobe (2013) 1.14

Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice. Physiol Genomics (2003) 1.13

Disruption of the human gut microbiota following Norovirus infection. PLoS One (2012) 1.13

Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res (2003) 1.12

Impaired beta-cell function in human aging: response to nicotinic acid-induced insulin resistance. J Clin Endocrinol Metab (2006) 1.12

Epidemiology of Clostridium difficile infection. J Pharm Pract (2013) 1.10

Characterization of the cryptic Escherichia lineages: rapid identification and prevalence. Environ Microbiol (2011) 1.10

Clostridium difficile and the microbiota. J Clin Invest (2014) 1.09

Ecological succession of bacterial communities during conventionalization of germ-free mice. Appl Environ Microbiol (2012) 1.09

Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study. Curr Diab Rep (2013) 1.09

Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population. J Bone Miner Res (2004) 1.08

Clonal structure and variation in virulence of Salmonella enteritidis isolated from mice, chickens, and humans. J AOAC Int (2006) 1.08

Explaining unexplained diarrhea and associating risks and infections. Anim Health Res Rev (2007) 1.08

The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages. J Immunol (2010) 1.08

Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis. Infect Immun (2011) 1.07

Limitation of the homeostasis model assessment to predict insulin resistance and beta-cell dysfunction in older people. J Clin Endocrinol Metab (2005) 1.07

Escherichia coli isolates that carry vat, fyuA, chuA, and yfcV efficiently colonize the urinary tract. Infect Immun (2012) 1.06

Poor functional status as a risk factor for severe Clostridium difficile infection in hospitalized older adults. J Am Geriatr Soc (2013) 1.05

Laser capture microdissection and metagenomic analysis of intact mucosa-associated microbial communities of human colon. Appl Microbiol Biotechnol (2010) 1.05

Clostridium difficile ribotype diversity at six health care institutions in the United States. J Clin Microbiol (2013) 1.04

Distinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages. J Biol Chem (2011) 1.04

Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase. J Biol Chem (2005) 1.03

Effect of sample storage conditions on culture-independent bacterial community measures in cystic fibrosis sputum specimens. J Clin Microbiol (2011) 1.03

Therapies for necrotising fasciitis. Expert Opin Biol Ther (2006) 1.03

Specific leukotriene receptors couple to distinct G proteins to effect stimulation of alveolar macrophage host defense functions. J Immunol (2007) 1.03