Published in J Bone Miner Res on August 01, 2003
Design of aging intervention studies: the NIA interventions testing program. Age (Dordr) (2008) 2.14
Bone mass is inversely proportional to Dkk1 levels in mice. Bone (2007) 1.71
Molecular genetic studies of gene identification for osteoporosis: a 2004 update. J Bone Miner Res (2006) 1.52
Pleiotropic patterns of quantitative trait loci for 70 murine skeletal traits. Genetics (2008) 1.18
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res (2013) 1.08
Genetics of the musculoskeletal system: a pleiotropic approach. J Bone Miner Res (2008) 1.06
Genetically determined phenotype covariation networks control bone strength. J Bone Miner Res (2010) 1.06
Evidence for pleiotropic factors in genetics of the musculoskeletal system. Bone (2010) 1.06
Three-locus and four-locus QTL interactions influence mouse insulin-like growth factor-I. Physiol Genomics (2006) 0.98
Whole bone mechanics and bone quality. Clin Orthop Relat Res (2011) 0.95
Mammalian mRNA splice-isoform selection is tightly controlled. Genetics (2006) 0.92
Phenotypic integration among trabecular and cortical bone traits establishes mechanical functionality of inbred mouse vertebrae. J Bone Miner Res (2009) 0.91
The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice. Calcif Tissue Int (2010) 0.89
Quantitative trait loci modulate vertebral morphology and mechanical properties in a population of 18-month-old genetically heterogeneous mice. Bone (2006) 0.85
Quantitative genetics of cortical bone mass in healthy 10-year-old children from the Fels Longitudinal Study. Bone (2006) 0.85
Alleles that modulate late life hearing in genetically heterogeneous mice. Neurobiol Aging (2012) 0.84
Systems analysis of bone. Wiley Interdiscip Rev Syst Biol Med (2010) 0.84
Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans. Bone (2007) 0.79
Preservation of femoral bone thickness in middle age predicts survival in genetically heterogeneous mice. Aging Cell (2011) 0.79
Dissection of complex adult traits in a mouse synthetic population. Genome Res (2012) 0.79
Bone disorders in experimentally induced liver disease in growing rats. World J Gastroenterol (2005) 0.79
Association studies of ALOX5 and bone mineral density in healthy adults. Osteoporos Int (2007) 0.79
Modulation of unloading-induced bone loss in mice with altered ERK signaling. Mamm Genome (2015) 0.78
Anabolic actions of Notch on mature bone. Proc Natl Acad Sci U S A (2016) 0.76
Aged male rats regenerate cortical bone with reduced osteocyte density and reduced secretion of nitric oxide after mechanical stimulation. Calcif Tissue Int (2013) 0.75
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A (2010) 8.05
Clostridium difficile ribotype does not predict severe infection. Clin Infect Dis (2012) 4.34
Rapamycin slows aging in mice. Aging Cell (2012) 3.76
Research capacity. Enabling the genomic revolution in Africa. Science (2014) 3.05
Focused cardiac ultrasound in the emergent setting: a consensus statement of the American Society of Echocardiography and American College of Emergency Physicians. J Am Soc Echocardiogr (2010) 2.73
Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases. J Clin Oncol (2003) 2.69
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice. Aging Cell (2008) 2.65
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab (2005) 2.59
Neurocognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: results of a randomized phase III trial. J Clin Oncol (2004) 2.55
Age-associated activation of epigenetically repressed genes in the mouse. Genetics (2003) 2.24
High-normal serum uric acid increases risk of early progressive renal function loss in type 1 diabetes: results of a 6-year follow-up. Diabetes Care (2010) 2.12
Multiplex stress resistance in cells from long-lived dwarf mice. FASEB J (2003) 2.04
Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant. J Gerontol A Biol Sci Med Sci (2004) 2.03
Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age. J Gerontol A Biol Sci Med Sci (2009) 2.02
Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice. Aging Cell (2002) 1.90
Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone. Aging Cell (2006) 1.89
Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell (2013) 1.71
Bone mass is inversely proportional to Dkk1 levels in mice. Bone (2007) 1.71
Mupirocin-based decolonization of Staphylococcus aureus carriers in residents of 2 long-term care facilities: a randomized, double-blind, placebo-controlled trial. Clin Infect Dis (2003) 1.69
The thioredoxin reductase/thioredoxin system: novel redox targets for cancer therapy. Cancer Biol Ther (2004) 1.67
Bone tissue compositional differences in women with and without osteoporotic fracture. Bone (2006) 1.63
Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Mol Endocrinol (2002) 1.61
Comparison between Society of Thoracic Surgeons score and logistic EuroSCORE for predicting mortality in patients referred for transcatheter aortic valve implantation. Cardiovasc Revasc Med (2011) 1.57
New model of health promotion and disease prevention for the 21st century. BMJ (2008) 1.53
Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice. Mol Cell Biol (2009) 1.52
Three-dimensional micro-computed tomographic imaging of alveolar bone in experimental bone loss or repair. J Periodontol (2007) 1.50
Unique rodent model of distraction osteogenesis of the mandible. Ann Plast Surg (2002) 1.49
Noninvasive Raman tomographic imaging of canine bone tissue. J Biomed Opt (2008) 1.49
Brittle IV mouse model for osteogenesis imperfecta IV demonstrates postpubertal adaptations to improve whole bone strength. J Bone Miner Res (2004) 1.47
Lead-in phase to randomized trial of motexafin gadolinium and whole-brain radiation for patients with brain metastases: centralized assessment of magnetic resonance imaging, neurocognitive, and neurologic end points. J Clin Oncol (2002) 1.47
Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress. J Gerontol A Biol Sci Med Sci (2008) 1.43
Parathyroid hormone mediates bone growth through the regulation of osteoblast proliferation and differentiation. Bone (2007) 1.40
Upper-extremity deep vein thrombosis. South Med J (2003) 1.39
Pursuing the longevity dividend: scientific goals for an aging world. Ann N Y Acad Sci (2007) 1.37
Stress resistance and aging: influence of genes and nutrition. Mech Ageing Dev (2006) 1.36
Motexafin gadolinium combined with prompt whole brain radiotherapy prolongs time to neurologic progression in non-small-cell lung cancer patients with brain metastases: results of a phase III trial. Int J Radiat Oncol Biol Phys (2008) 1.33
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. FASEB J (2010) 1.33
An application of nanoindentation technique to measure bone tissue Lamellae properties. J Biomech Eng (2005) 1.32
Subsurface and transcutaneous Raman spectroscopy and mapping using concentric illumination rings and collection with a circular fiber-optic array. Appl Spectrosc (2007) 1.30
Complications and outcome of balloon aortic valvuloplasty in high-risk or inoperable patients. JACC Cardiovasc Interv (2010) 1.29
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci (2012) 1.29
Anabolic actions of PTH (1-34): use of a novel tissue engineering model to investigate temporal effects on bone. Bone (2005) 1.28
Developing consistently reproducible intervertebral disc degeneration at rat caudal spine by using needle puncture. J Neurosurg Spine (2009) 1.28
American Society of Echocardiography clinical recommendations for multimodality cardiovascular imaging of patients with hypertrophic cardiomyopathy: Endorsed by the American Society of Nuclear Cardiology, Society for Cardiovascular Magnetic Resonance, and Society of Cardiovascular Computed Tomography. J Am Soc Echocardiogr (2011) 1.28
Transcutaneous Raman spectroscopy of murine bone in vivo. Appl Spectrosc (2009) 1.26
Transcutaneous fiber optic Raman spectroscopy of bone using annular illumination and a circular array of collection fibers. J Biomed Opt (2007) 1.26
Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines. Cancer Res (2005) 1.25
Motexafin gadolinium generates reactive oxygen species and induces apoptosis in sensitive and highly resistant multiple myeloma cells. Blood (2004) 1.23
Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan. Am J Physiol Endocrinol Metab (2012) 1.23
Procalcitonin levels associate with severity of Clostridium difficile infection. PLoS One (2013) 1.22
Alendronate treatment of the brtl osteogenesis imperfecta mouse improves femoral geometry and load response before fracture but decreases predicted material properties and has detrimental effects on osteoblasts and bone formation. J Bone Miner Res (2009) 1.21
Age-dependent defects in TCR-triggered cytoskeletal rearrangement in CD4+ T cells. J Immunol (2002) 1.20
Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines. Cancer Res (2005) 1.20
Comparison of gene expression of 2-mo denervated, 2-mo stimulated-denervated, and control rat skeletal muscles. Physiol Genomics (2005) 1.19
Microcystic adnexal carcinoma: review of a potential diagnostic pitfall and management. Cutis (2014) 1.18
Fibroblasts from long-lived bird species are resistant to multiple forms of stress. J Exp Biol (2011) 1.18
Osteocyte lacuna size and shape in women with and without osteoporotic fracture. J Biomech (2004) 1.18
Dose-response effect of human equivalent radiation in the murine mandible: Part II. A biomechanical assessment. Plast Reconstr Surg (2011) 1.18
Subclinical brain embolization in left-sided infective endocarditis: results from the evaluation by MRI of the brains of patients with left-sided intracardiac solid masses (EMBOLISM) pilot study. Circulation (2009) 1.17
Perception of and attitude towards mental illness in Oman. Int J Soc Psychiatry (2002) 1.16
Science fact and the SENS agenda. What can we reasonably expect from ageing research? EMBO Rep (2005) 1.16
Focal adhesion kinase expression during mandibular distraction osteogenesis: evidence for mechanotransduction. Plast Reconstr Surg (2003) 1.15
Signal transduction in the aging immune system. Curr Opin Immunol (2005) 1.14
Quantitative trait loci for insulin-like growth factor I, leptin, thyroxine, and corticosterone in genetically heterogeneous mice. Physiol Genomics (2003) 1.13
Understanding increased mortality in Clostridium difficile-infected older adults. Clin Infect Dis (2013) 1.13
Motexafin gadolinium: a novel redox active drug for cancer therapy. Semin Cancer Biol (2006) 1.13
Genetic loci that influence cause of death in a heterogeneous mouse stock. J Gerontol A Biol Sci Med Sci (2004) 1.12
Impaired beta-cell function in human aging: response to nicotinic acid-induced insulin resistance. J Clin Endocrinol Metab (2006) 1.12
Thrombospondin-2 influences the proportion of cartilage and bone during fracture healing. J Bone Miner Res (2009) 1.10
Earliest mineral and matrix changes in force-induced musculoskeletal disease as revealed by Raman microspectroscopic imaging. J Bone Miner Res (2004) 1.09
Uric acid lowering to prevent kidney function loss in diabetes: the preventing early renal function loss (PERL) allopurinol study. Curr Diab Rep (2013) 1.09
Quantitative trait loci that modulate femoral mechanical properties in a genetically heterogeneous mouse population. J Bone Miner Res (2004) 1.08
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res (2013) 1.08
Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice. J Gerontol A Biol Sci Med Sci (2013) 1.08
Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible. Plast Reconstr Surg (2012) 1.08
Fibroblasts from long-lived Snell dwarf mice are resistant to oxygen-induced in vitro growth arrest. Aging Cell (2006) 1.08
Limitation of the homeostasis model assessment to predict insulin resistance and beta-cell dysfunction in older people. J Clin Endocrinol Metab (2005) 1.07
Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence. Exp Gerontol (2012) 1.07
Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice. Mech Ageing Dev (2006) 1.07
Clinical profile, prognostic implication, and response to treatment of pulmonary hypertension in patients with severe aortic stenosis. Am J Cardiol (2011) 1.07
Genetic modulation of hormone levels and life span in hybrids between laboratory and wild-derived mice. J Gerontol A Biol Sci Med Sci (2006) 1.06
Role of Bcl2 in osteoclastogenesis and PTH anabolic actions in bone. J Bone Miner Res (2008) 1.05
Optical clearing in transcutaneous Raman spectroscopy of murine cortical bone tissue. J Biomed Opt (2008) 1.05
Poor functional status as a risk factor for severe Clostridium difficile infection in hospitalized older adults. J Am Geriatr Soc (2013) 1.05
Polymerase chain reaction in high surface-to-volume ratio SiO2 microstructures. Anal Chem (2004) 1.04
Extended longevity of wild-derived mice is associated with peroxidation-resistant membranes. Mech Ageing Dev (2006) 1.04
Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy. Bone (2012) 1.04
Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes. Free Radic Biol Med (2009) 1.04