AllerTOP--a server for in silico prediction of allergens.

Identification of B-cell epitopes in an antigen for inducing specific class of antibodies. Biol Direct (2013) 0.87

ProInflam: a webserver for the prediction of proinflammatory antigenicity of peptides and proteins. J Transl Med (2016) 0.77

AllerTOP v.2--a server for in silico prediction of allergens. J Mol Model (2014) 0.76

Overexpression of biologically safe Rorippa indica defensin enhances aphid tolerance in Brassica juncea. Planta (2017) 0.75

Comprehensive in silico allergenicity assessment of novel protein engineered chimeric Cry proteins for safe deployment in crops. BMC Biotechnol (2017) 0.75

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Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol (2004) 5.13

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Peptide quantitative structure-activity relationships, a multivariate approach. J Med Chem (1987) 1.75

Computational tools for the study of allergens. Allergy (2003) 1.61

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Allergenicity prediction by protein sequence. FASEB J (2003) 1.41

Classification of G-protein coupled receptors by alignment-independent extraction of principal chemical properties of primary amino acid sequences. Protein Sci (2002) 1.33

Predicting allergenic proteins using wavelet transform. Bioinformatics (2004) 1.21

Allermatch, a webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines. BMC Bioinformatics (2004) 1.14

AllerHunter: a SVM-pairwise system for assessment of allergenicity and allergic cross-reactivity in proteins. PLoS One (2009) 1.09

Why are some proteins allergens? Toxicol Sci (2000) 1.08

Intestinal worms and human allergy. Parasite Immunol (2005) 1.07

Supervised identification of allergen-representative peptides for in silico detection of potentially allergenic proteins. Bioinformatics (2004) 1.07

AllerTool: a web server for predicting allergenicity and allergic cross-reactivity in proteins. Bioinformatics (2006) 1.04

Prediction of food protein allergenicity: a bioinformatic learning systems approach. In Silico Biol (2002) 0.98

An attempt to define allergen-specific molecular surface features: a bioinformatic approach. Bioinformatics (2005) 0.90

Allergens as eukaryotic proteins lacking bacterial homologues. Mol Immunol (2007) 0.83

Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response. J Exp Med (2004) 3.48

Benchmarking B cell epitope prediction: underperformance of existing methods. Protein Sci (2004) 2.70

VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines. BMC Bioinformatics (2007) 2.10

JenPep: a database of quantitative functional peptide data for immunology. Bioinformatics (2002) 1.75

Identifiying human MHC supertypes using bioinformatic methods. J Immunol (2004) 1.72

JenPep: a novel computational information resource for immunobiology and vaccinology. J Chem Inf Comput Sci (2003) 1.64

Analysis of peptide-protein binding using amino acid descriptors: prediction and experimental verification for human histocompatibility complex HLA-A0201. J Med Chem (2005) 1.62

SVRMHC prediction server for MHC-binding peptides. BMC Bioinformatics (2006) 1.59

Hydrazones of 1,2-benzisothiazole hydrazides: synthesis, antimicrobial activity and QSAR investigations. Eur J Med Chem (2002) 1.59

In silico identification of supertypes for class II MHCs. J Immunol (2005) 1.52

MHCPred: A server for quantitative prediction of peptide-MHC binding. Nucleic Acids Res (2003) 1.48

Benchmarking pK(a) prediction. BMC Biochem (2006) 1.47

Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores. BMC Bioinformatics (2006) 1.41

Identifying candidate subunit vaccines using an alignment-independent method based on principal amino acid properties. Vaccine (2006) 1.37

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination. Proc Natl Acad Sci U S A (2008) 1.34

EpiJen: a server for multistep T cell epitope prediction. BMC Bioinformatics (2006) 1.26

Additive method for the prediction of protein-peptide binding affinity. Application to the MHC class I molecule HLA-A*0201. J Proteome Res (2003) 1.23

Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models. BMC Bioinformatics (2006) 1.22

Harnessing bioinformatics to discover new vaccines. Drug Discov Today (2007) 1.22

T-cell epitope vaccine design by immunoinformatics. Open Biol (2013) 1.20

MHCPred: bringing a quantitative dimension to the online prediction of MHC binding. Appl Bioinformatics (2003) 1.19

Bacterial bioinformatics: pathogenesis and the genome. J Mol Microbiol Biotechnol (2002) 1.18

AntigenDB: an immunoinformatics database of pathogen antigens. Nucleic Acids Res (2009) 1.18

Computer-aided biotechnology: from immuno-informatics to reverse vaccinology. Trends Biotechnol (2008) 1.13

Towards the chemometric dissection of peptide--HLA-A*0201 binding affinity: comparison of local and global QSAR models. J Comput Aided Mol Des (2005) 1.11

PPD v1.0--an integrated, web-accessible database of experimentally determined protein pKa values. Nucleic Acids Res (2006) 1.10

FIMM, a database of functional molecular immunology: update 2002. Nucleic Acids Res (2002) 1.06

Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity. PLoS Pathog (2010) 1.06

Transporter associated with antigen processing preselection of peptides binding to the MHC: a bioinformatic evaluation. J Immunol (2004) 1.04

BPROMPT: A consensus server for membrane protein prediction. Nucleic Acids Res (2003) 1.03

Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. Eur J Med Chem (2009) 1.02

On the hierarchical classification of G protein-coupled receptors. Bioinformatics (2007) 1.01

Toward an atomistic understanding of the immune synapse: large-scale molecular dynamics simulation of a membrane-embedded TCR-pMHC-CD4 complex. Mol Immunol (2007) 1.01

Quantitative online prediction of peptide binding to the major histocompatibility complex. J Mol Graph Model (2004) 1.01

LIPPRED: A web server for accurate prediction of lipoprotein signal sequences and cleavage sites. Bioinformation (2006) 1.01

Physicochemical explanation of peptide binding to HLA-A*0201 major histocompatibility complex: a three-dimensional quantitative structure-activity relationship study. Proteins (2002) 1.00

MHC class I bound to an immunodominant Theileria parva epitope demonstrates unconventional presentation to T cell receptors. PLoS Pathog (2010) 0.99

Greater CD8+ TCR heterogeneity and functional flexibility in HIV-2 compared to HIV-1 infection. J Immunol (2003) 0.99

HLA-A3 supermotif defined by quantitative structure-activity relationship analysis. Protein Eng (2003) 0.97

On the hydrophobicity of peptides: Comparing empirical predictions of peptide log P values. Bioinformation (2006) 0.97

Coupling in silico and in vitro analysis of peptide-MHC binding: a bioinformatic approach enabling prediction of superbinding peptides and anchorless epitopes. J Immunol (2004) 0.97

Molecular basis of peptide recognition by the TCR: affinity differences calculated using large scale computing. J Immunol (2005) 0.96

Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection. J Gen Virol (2005) 0.95

Proteomic applications of automated GPCR classification. Proteomics (2007) 0.95

New horizons in mouse immunoinformatics: reliable in silico prediction of mouse class I histocompatibility major complex peptide binding affinity. Org Biomol Chem (2004) 0.92

Peptide binding prediction for the human class II MHC allele HLA-DP2: a molecular docking approach. BMC Struct Biol (2011) 0.91

Toward prediction of class II mouse major histocompatibility complex peptide binding affinity: in silico bioinformatic evaluation using partial least squares, a robust multivariate statistical technique. J Chem Inf Model (2006) 0.91

Immunoinformatics. Predicting immunogenicity in silico. Preface. Methods Mol Biol (2007) 0.90

MHCPred 2.0: an updated quantitative T-cell epitope prediction server. Appl Bioinformatics (2006) 0.90

A comparative molecular similarity index analysis (CoMSIA) study identifies an HLA-A2 binding supermotif. J Comput Aided Mol Des (2003) 0.90

Large-scale molecular dynamics simulations of HLA-A*0201 complexed with a tumor-specific antigenic peptide: can the alpha3 and beta2m domains be neglected? J Comput Chem (2004) 0.88

In silico prediction of peptide binding affinity to class I mouse major histocompatibility complexes: a comparative molecular similarity index analysis (CoMSIA) study. J Chem Inf Model (2005) 0.88

Peptide length significantly influences in vitro affinity for MHC class II molecules. Immunome Res (2008) 0.88

Peptide recognition by the T cell receptor: comparison of binding free energies from thermodynamic integration, Poisson-Boltzmann and linear interaction energy approximations. Philos Trans A Math Phys Eng Sci (2005) 0.87

Toward the discovery of vaccine adjuvants: coupling in silico screening and in vitro analysis of antagonist binding to human and mouse CCR4 receptors. PLoS One (2009) 0.86

Peptide binding to the HLA-DRB1 supertype: a proteochemometrics analysis. Eur J Med Chem (2009) 0.86

Class I T-cell epitope prediction: improvements using a combination of proteasome cleavage, TAP affinity, and MHC binding. Mol Immunol (2006) 0.86

In silico prediction of peptide-MHC binding affinity using SVRMHC. Methods Mol Biol (2007) 0.85

Toward bacterial protein sub-cellular location prediction: single-class discrimminant models for all gram- and gram+ compartments. Bioinformation (2006) 0.85

Toward the atomistic simulation of T cell epitopes automated construction of MHC: peptide structures for free energy calculations. J Mol Graph Model (2007) 0.84

Multi-class subcellular location prediction for bacterial proteins. Bioinformation (2006) 0.84

Optimizing amino acid groupings for GPCR classification. Bioinformatics (2008) 0.84

Prediction of steady-state volume of distribution of acidic drugs by quantitative structure-pharmacokinetics relationships. J Pharm Sci (2011) 0.84

Modeling the peptide-T cell receptor interaction by the comparative molecular similarity indices analysis-soft independent modeling of class analogy technique. J Med Chem (2006) 0.83

Aminothiazole derivatives with antidegenerative activity on cartilage. Bioorg Med Chem (2003) 0.83

Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes. PLoS One (2009) 0.83

EpiTOP--a proteochemometric tool for MHC class II binding prediction. Bioinformatics (2010) 0.83

Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity. BMC Struct Biol (2006) 0.83

Predicting class I major histocompatibility complex (MHC) binders using multivariate statistics: comparison of discriminant analysis and multiple linear regression. J Chem Inf Model (2007) 0.83

Immunoinformatic evaluation of multiple epitope ensembles as vaccine candidates: E coli 536. Bioinformation (2012) 0.82

GPCRTree: online hierarchical classification of GPCR function. BMC Res Notes (2008) 0.82

Quantitative approaches to computational vaccinology. Immunol Cell Biol (2002) 0.82

TATPred: a Bayesian method for the identification of twin arginine translocation pathway signal sequences. Bioinformation (2006) 0.81

Identification of the HLA-DM/HLA-DR interface. Mol Immunol (2007) 0.81

An update on the functional molecular immunology (FIMM) database. Appl Bioinformatics (2005) 0.81

Preparation and evaluation of isosorbide mononitrate hydrogels for topical fissure treatment. Curr Drug Deliv (2012) 0.80

Quantitative structure-activity relationships and the prediction of MHC supermotifs. Methods (2004) 0.80

Lipocalins in bioscience: the first family gathering. Bioessays (2004) 0.79

Toward the prediction of class I and II mouse major histocompatibility complex-peptide-binding affinity: in silico bioinformatic step-by-step guide using quantitative structure-activity relationships. Methods Mol Biol (2007) 0.79

Novel perforin mutation in a patient with hemophagocytic lymphohistiocytosis and CD45 abnormal splicing. Am J Med Genet A (2003) 0.79

A comparative molecular similarity indices (CoMSIA) study of peptide binding to the HLA-A3 superfamily. Bioorg Med Chem (2003) 0.79

Combining algorithms to predict bacterial protein sub-cellular location: Parallel versus concurrent implementations. Bioinformation (2006) 0.79

Receptor-ligand binding sites and virtual screening. Curr Med Chem (2006) 0.79

From 'perfect mix' to 'potion magique'-- regulatory T cells and anti-inflammatory cytokines as adjuvant targets. Nat Rev Microbiol (2008) 0.79

Quantitative structure--clearance relationships of acidic drugs. Mol Pharm (2013) 0.78

MHC Class II Binding Prediction-A Little Help from a Friend. J Biomed Biotechnol (2010) 0.78

Using databases and data mining in vaccinology. Expert Opin Drug Discov (2007) 0.78

Beta barrel trans-membrane proteins: Enhanced prediction using a Bayesian approach. Bioinformation (2006) 0.78

AllergenFP: allergenicity prediction by descriptor fingerprints. Bioinformatics (2013) 0.78

Empirical prediction of peptide octanol-water partition coefficients. Bioinformation (2006) 0.78

Static energy analysis of MHC class I and class II peptide-binding affinity. Methods Mol Biol (2007) 0.77

AllerTOP v.2--a server for in silico prediction of allergens. J Mol Model (2014) 0.76

Present perspectives on the automated classification of the G-protein coupled receptors (GPCRs) at the protein sequence level. Curr Top Med Chem (2011) 0.76

HLA-DP2 binding prediction by molecular dynamics simulations. Protein Sci (2011) 0.76

Quantitative structure--plasma protein binding relationships of acidic drugs. J Pharm Sci (2012) 0.76