Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.
|
N Engl J Med
|
2012
|
11.86
|
2
|
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism.
|
N Engl J Med
|
2013
|
7.76
|
3
|
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial.
|
Lancet
|
2007
|
5.41
|
4
|
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.
|
N Engl J Med
|
2010
|
5.06
|
5
|
Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography.
|
JAMA
|
2006
|
4.75
|
6
|
Rivaroxaban for thromboprophylaxis in acutely ill medical patients.
|
N Engl J Med
|
2013
|
4.43
|
7
|
Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial.
|
JAMA
|
2004
|
3.55
|
8
|
Serial 2-point ultrasonography plus D-dimer vs whole-leg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: a randomized controlled trial.
|
JAMA
|
2008
|
3.10
|
9
|
Bidirectional relation between inflammation and coagulation.
|
Circulation
|
2004
|
3.00
|
10
|
Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial.
|
Lancet
|
2003
|
2.86
|
11
|
The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: a meta-analysis.
|
J Am Coll Cardiol
|
2003
|
2.71
|
12
|
Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study.
|
BMJ
|
2012
|
2.38
|
13
|
Comparing the diagnostic performance of 2 clinical decision rules to rule out deep vein thrombosis in primary care patients.
|
Ann Fam Med
|
2011
|
2.34
|
14
|
Diagnostic strategies for excluding pulmonary embolism in clinical outcome studies. A systematic review.
|
Ann Intern Med
|
2003
|
2.33
|
15
|
The incidence of recurrent venous thromboembolism after treatment with vitamin K antagonists in relation to time since first event: a meta-analysis.
|
Arch Intern Med
|
2003
|
2.33
|
16
|
The effect of low molecular weight heparin on survival in patients with advanced malignancy.
|
J Clin Oncol
|
2005
|
2.31
|
17
|
Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study.
|
Ann Intern Med
|
2011
|
2.28
|
18
|
Preoperative or postoperative start of prophylaxis for venous thromboembolism with low-molecular-weight heparin in elective hip surgery?
|
Arch Intern Med
|
2002
|
2.16
|
19
|
Direct thrombin inhibitors.
|
N Engl J Med
|
2005
|
2.15
|
20
|
Risk of deep vein thrombosis and pulmonary embolism in asthma.
|
Eur Respir J
|
2012
|
2.08
|
21
|
Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts.
|
BMJ
|
2010
|
1.99
|
22
|
Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1.
|
Circ Res
|
2006
|
1.95
|
23
|
Selective testing for thrombophilia in patients with first venous thrombosis: results from a retrospective family cohort study on absolute thrombotic risk for currently known thrombophilic defects in 2479 relatives.
|
Blood
|
2009
|
1.93
|
24
|
Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism.
|
Arch Intern Med
|
2004
|
1.92
|
25
|
Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: a systematic review.
|
Crit Care Med
|
2005
|
1.82
|
26
|
Use of a clinical decision rule in combination with D-dimer concentration in diagnostic workup of patients with suspected pulmonary embolism: a prospective management study.
|
Arch Intern Med
|
2002
|
1.81
|
27
|
Thrombotic risk during oral contraceptive use and pregnancy in women with factor V Leiden or prothrombin mutation: a rational approach to contraception.
|
Blood
|
2011
|
1.63
|
28
|
Statin treatment and the risk of recurrent pulmonary embolism.
|
Eur Heart J
|
2013
|
1.58
|
29
|
Cardiovascular risk assessment in haemophilia patients.
|
Thromb Haemost
|
2010
|
1.57
|
30
|
Use of oral glucocorticoids and the risk of pulmonary embolism: a population-based case-control study.
|
Chest
|
2013
|
1.55
|
31
|
Validity and clinical utility of the simplified Wells rule for assessing clinical probability for the exclusion of pulmonary embolism.
|
Thromb Haemost
|
2009
|
1.51
|
32
|
Risk profile and clinical outcome of symptomatic subsegmental acute pulmonary embolism.
|
Blood
|
2013
|
1.51
|
33
|
Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A.
|
Circulation
|
2010
|
1.50
|
34
|
Thrombosis prophylaxis in patient populations with a central venous catheter: a systematic review.
|
Arch Intern Med
|
2003
|
1.49
|
35
|
Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing, and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study.
|
Ann Intern Med
|
2014
|
1.42
|
36
|
Thrombin-activatable fibrinolysis inhibitor in hypothyroidism and hyperthyroxinaemia.
|
Thromb Haemost
|
2012
|
1.40
|
37
|
Bioavailability of subcutaneous low-molecular-weight heparin to patients on vasopressors.
|
Lancet
|
2002
|
1.32
|
38
|
A C1173T dimorphism in the VKORC1 gene determines coumarin sensitivity and bleeding risk.
|
PLoS Med
|
2005
|
1.20
|
39
|
Guidelines were developed for data collection from medical records for use in retrospective analyses.
|
J Clin Epidemiol
|
2005
|
1.20
|
40
|
Hypercoagulable state in Cushing's syndrome: a systematic review.
|
J Clin Endocrinol Metab
|
2009
|
1.17
|
41
|
Association of V617F Jak2 mutation with the risk of thrombosis among patients with essential thrombocythaemia or idiopathic myelofibrosis: a systematic review.
|
Thromb Res
|
2009
|
1.17
|
42
|
Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.
|
Haematologica
|
2002
|
1.16
|
43
|
Effects of human cytomegalovirus infection on the coagulation system.
|
Thromb Haemost
|
2005
|
1.14
|
44
|
Embolus location affects the sensitivity of a rapid quantitative D-dimer assay in the diagnosis of pulmonary embolism.
|
Am J Respir Crit Care Med
|
2002
|
1.14
|
45
|
Cerebral white matter lesions predict both ischemic strokes and myocardial infarctions in patients with established atherosclerotic disease.
|
Atherosclerosis
|
2005
|
1.14
|
46
|
Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers.
|
Circulation
|
2002
|
1.13
|
47
|
The natural course of hemodynamically stable pulmonary embolism: Clinical outcome and risk factors in a large prospective cohort study.
|
Chest
|
2007
|
1.12
|
48
|
The hemostatic balance in HIV-infected patients with and without antiretroviral therapy: partial restoration with antiretroviral therapy.
|
AIDS Patient Care STDS
|
2009
|
1.11
|
49
|
Simplification of the diagnostic management of suspected deep vein thrombosis.
|
Arch Intern Med
|
2002
|
1.09
|
50
|
Influence of smoking on incidence and prevalence of peripheral arterial disease.
|
J Vasc Surg
|
2004
|
1.05
|
51
|
Incidental venous thromboembolism in cancer patients: prevalence and consequence.
|
Thromb Res
|
2010
|
1.04
|
52
|
Coagulation activation and microparticle-associated coagulant activity in cancer patients. An exploratory prospective study.
|
Thromb Haemost
|
2012
|
1.04
|
53
|
Travel and the risk of symptomatic venous thromboembolism.
|
Thromb Haemost
|
2003
|
1.03
|
54
|
Bleeding in patients receiving vitamin K antagonists who would have been excluded from trials on which the indication for anticoagulation was based.
|
Blood
|
2008
|
1.01
|
55
|
Subclinical hypothyroidism and deep venous thrombosis. A pilot cross-sectional study.
|
Thromb Haemost
|
2007
|
1.01
|
56
|
Combined utility of brain natriuretic peptide and cardiac troponin T may improve rapid triage and risk stratification in normotensive patients with pulmonary embolism.
|
Int J Cardiol
|
2006
|
1.00
|
57
|
A clinical prediction model for the presence of peripheral arterial disease--the benefit of screening individuals before initiation of measurement of the ankle-brachial index: an observational study.
|
Vasc Med
|
2007
|
0.98
|
58
|
Benchmark for time in therapeutic range in venous thromboembolism: a systematic review and meta-analysis.
|
PLoS One
|
2012
|
0.96
|
59
|
Increasing levels of free thyroxine as a risk factor for a first venous thrombosis: a case-control study.
|
Blood
|
2010
|
0.96
|
60
|
Acute pulmonary embolism. Part 2: treatment.
|
Nat Rev Cardiol
|
2010
|
0.96
|
61
|
Idiopathic superficial thrombophlebitis and the incidence of cancer in primary care patients.
|
Ann Fam Med
|
2010
|
0.95
|
62
|
Estimates of risk of venous thrombosis during pregnancy and puerperium are not influenced by diagnostic suspicion and referral basis.
|
Am J Obstet Gynecol
|
2004
|
0.95
|
63
|
Secondary prophylaxis with warfarin for venous thromboembolism.
|
N Engl J Med
|
2003
|
0.95
|
64
|
Treatment of venous thromboembolism in patients with cancer: subgroup analysis of the Matisse clinical trials.
|
Thromb Haemost
|
2009
|
0.94
|
65
|
Treatment with recombinant human activated protein C obviates additional anticoagulation during continuous venovenous hemofiltration in patients with severe sepsis.
|
Intensive Care Med
|
2003
|
0.94
|
66
|
Symptomatic peripheral arterial disease: the value of a validated questionnaire and a clinical decision rule.
|
Br J Gen Pract
|
2006
|
0.93
|
67
|
A lower risk of recurrent venous thrombosis in women compared with men is explained by sex-specific risk factors at time of first venous thrombosis in thrombophilic families.
|
Blood
|
2009
|
0.92
|
68
|
Smoking and the patency of lower extremity bypass grafts: a meta-analysis.
|
J Vasc Surg
|
2005
|
0.92
|
69
|
Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: a systematic review.
|
Haematologica
|
2005
|
0.91
|
70
|
Prothrombin 20210A mutation: a mild risk factor for venous thromboembolism but not for arterial thrombotic disease and pregnancy-related complications in a family study.
|
Arch Intern Med
|
2004
|
0.91
|
71
|
Low incidence of deep vein thrombosis after knee arthroscopy without thromboprophylaxis: a prospective cohort study of 335 patients.
|
Acta Orthop
|
2006
|
0.91
|
72
|
The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations.
|
PLoS Med
|
2007
|
0.91
|
73
|
Incidental venous thromboembolism in ambulatory cancer patients receiving chemotherapy.
|
Thromb Haemost
|
2010
|
0.89
|
74
|
Edoxaban for treatment of venous thromboembolism in patients with cancer. Rationale and design of the Hokusai VTE-cancer study.
|
Thromb Haemost
|
2015
|
0.89
|
75
|
Concerns in using multi-detector computed tomography for diagnosing pulmonary embolism in daily practice. A cross-sectional analysis using expert opinion as reference standard.
|
Thromb Res
|
2012
|
0.88
|
76
|
Recombinant nematode anticoagulant protein c2, an inhibitor of the tissue factor/factor VIIa complex, in patients undergoing elective coronary angioplasty.
|
J Am Coll Cardiol
|
2003
|
0.88
|
77
|
Influenza infection and risk of acute pulmonary embolism.
|
Thromb J
|
2007
|
0.87
|
78
|
Recombinant factor VIIa reverses the anticoagulant effect of the long-acting pentasaccharide idraparinux in healthy volunteers.
|
Br J Haematol
|
2004
|
0.85
|
79
|
Acute pulmonary embolism. Part 1: epidemiology and diagnosis.
|
Nat Rev Cardiol
|
2010
|
0.85
|
80
|
Prevention and treatment of experimental thrombosis in rabbits with rivaroxaban (BAY 597939)--an oral, direct factor Xa inhibitor.
|
Thromb Haemost
|
2007
|
0.85
|
81
|
Dutch orthopedic thromboprophylaxis: a 5-year follow-up survey.
|
Acta Orthop
|
2009
|
0.85
|
82
|
Ruling out clinically suspected pulmonary embolism by assessment of clinical probability and D-dimer levels: a management study.
|
Thromb Haemost
|
2003
|
0.85
|
83
|
The risk of postthrombotic syndrome in children with congenital heart disease.
|
J Pediatr
|
2002
|
0.84
|
84
|
Diagnostic strategy using a modified clinical decision rule and D-dimer test to rule out pulmonary embolism in elderly in- and outpatients.
|
Thromb Haemost
|
2005
|
0.84
|
85
|
Clinical decision rule and D-dimer have lower clinical utility to exclude pulmonary embolism in cancer patients. Explanations and potential ameliorations.
|
Thromb Haemost
|
2010
|
0.84
|
86
|
Stress-induced hyperglycaemia and venous thromboembolism following total hip or total knee arthroplasty: analysis from the RECORD trials.
|
Thromb Haemost
|
2011
|
0.84
|
87
|
Applicability of the ankle-brachial-index measurement as screening device for high cardiovascular risk: an observational study.
|
BMC Cardiovasc Disord
|
2012
|
0.84
|
88
|
The risk of venous and arterial thrombosis in hyperhomocysteinaemia is low and mainly depends on concomitant thrombophilic defects.
|
Thromb Haemost
|
2007
|
0.83
|
89
|
Absolute annual incidences of first events of venous thromboembolism and arterial vascular events in individuals with elevated FVIII:c. A prospective family cohort study.
|
Thromb Haemost
|
2007
|
0.83
|
90
|
Rebound thrombin generation after heparin therapy in unstable angina. A randomized comparison between unfractionated and low-molecular-weight heparin.
|
J Am Coll Cardiol
|
2002
|
0.83
|
91
|
Managing reversal of direct oral anticoagulants in emergency situations. Anticoagulation Education Task Force White Paper.
|
Thromb Haemost
|
2016
|
0.82
|
92
|
The clinical usefulness of D-dimer testing in cancer patients with suspected deep venous thrombosis.
|
Arch Intern Med
|
2002
|
0.82
|
93
|
Predilution versus postdilution during continuous venovenous hemofiltration: a comparison of circuit thrombogenesis.
|
ASAIO J
|
2006
|
0.82
|
94
|
Recombinant nematode anticoagulant protein c2, a novel inhibitor of tissue factor-factor VIIa activity, abrogates endotoxin-induced coagulation in chimpanzees.
|
Thromb Haemost
|
2002
|
0.82
|
95
|
Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia.
|
Thromb Haemost
|
2009
|
0.82
|
96
|
Social aspects of genetic testing for factor V Leiden mutation in healthy individuals and their importance for daily practice.
|
Thromb Res
|
2004
|
0.82
|
97
|
Compliance of Dutch orthopedic departments with national guidelines on thromboprophylaxis. A survey of Dutch orthopedic thromboprohylaxis.
|
Acta Orthop
|
2005
|
0.82
|
98
|
Different risk of deep vein thrombosis and pulmonary embolism in carriers with factor V Leiden compared with non-carriers, but not in other thrombophilic defects. Results from a large retrospective family cohort study.
|
Haematologica
|
2009
|
0.82
|
99
|
Improving stroke prevention in patients with atrial fibrillation.
|
Trials
|
2013
|
0.81
|
100
|
Optimisation of the diagnostic strategy for suspected deep-vein thrombosis in primary care.
|
Thromb Haemost
|
2010
|
0.81
|
101
|
Absolute risk of venous and arterial thromboembolism in thrombophilic families is not increased by high thrombin-activatable fibrinolysis inhibitor (TAFI) levels.
|
Thromb Haemost
|
2008
|
0.81
|
102
|
Time-trends in treatment and cardiovascular events in patients with heart failure: a pharmacosurveillance study.
|
Eur J Heart Fail
|
2010
|
0.81
|
103
|
The influence of pituitary, adrenal, and parathyroid hormones on hemostasis and thrombosis.
|
Semin Thromb Hemost
|
2011
|
0.80
|
104
|
Hormones and cardiovascular disease: a shift in paradigm with clinical consequences?
|
Semin Thromb Hemost
|
2009
|
0.80
|
105
|
Long-term follow-up of patients with suspected deep vein thrombosis of the upper extremity: survival, risk factors and post-thrombotic syndrome.
|
Eur J Intern Med
|
2004
|
0.80
|
106
|
Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study.
|
Crit Care
|
2005
|
0.80
|
107
|
Hyperhomocysteinemia is not a risk factor for venous and arterial thrombosis, and is associated with elevated factor VIII levels.
|
Thromb Res
|
2008
|
0.80
|
108
|
Deep vein thrombosis after arthroscopic anterior cruciate ligament reconstruction: a prospective cohort study of 100 patients.
|
Arthroscopy
|
2013
|
0.79
|
109
|
Quality of life and the duration of treatment with vitamin K antagonists in patients with deep venous thrombosis.
|
Thromb Haemost
|
2003
|
0.79
|
110
|
Peripheral arterial disease: the gap between common practice and the Dutch College of General Practitioners guideline.
|
Eur J Gen Pract
|
2004
|
0.78
|
111
|
Systolic heart failure: a prothrombotic state.
|
Semin Thromb Hemost
|
2009
|
0.78
|
112
|
Idraparinux versus standard therapy in the treatment of deep venous thrombosis in cancer patients: a subgroup analysis of the Van Gogh DVT trial.
|
Thromb Haemost
|
2010
|
0.78
|
113
|
Risk of thromboembolism and bleeding after general surgery in patients with atrial fibrillation.
|
Am J Cardiol
|
2005
|
0.78
|
114
|
New anticoagulants: moving on from scientific results to clinical implementation.
|
Ann Med
|
2011
|
0.77
|
115
|
Biomarkers in pulmonary embolism.
|
Curr Opin Cardiol
|
2004
|
0.77
|
116
|
The incidence of recurrent venous thromboembolism in carriers of factor V Leiden is related to concomitant thrombophilic disorders.
|
Br J Haematol
|
2002
|
0.77
|
117
|
Endotoxaemia induces resistance to activated protein C in healthy humans.
|
Br J Haematol
|
2006
|
0.77
|
118
|
Recurrent deep venous thrombosis during optimal anticoagulation and overt hyperthyroidism: a case report.
|
Blood Coagul Fibrinolysis
|
2007
|
0.77
|
119
|
Quantitative trait locus for protein C in a family with thrombophilia.
|
Thromb Haemost
|
2010
|
0.77
|
120
|
Wells Rule and d-Dimer Testing to Rule Out Pulmonary Embolism: A Systematic Review and Individual-Patient Data Meta-analysis.
|
Ann Intern Med
|
2016
|
0.77
|
121
|
Incidence of postpartum haemorrhage in women receiving therapeutic doses of low-molecular-weight heparin: results of a retrospective cohort study.
|
BMJ Open
|
2011
|
0.77
|
122
|
Factor XI antisense oligonucleotide for venous thrombosis.
|
N Engl J Med
|
2015
|
0.77
|
123
|
Levels of prolactin in relation to coagulation factors and risk of venous thrombosis. Results of a large population-based case-control study (MEGA-study).
|
Thromb Haemost
|
2012
|
0.76
|
124
|
Clinically suspected acute recurrent pulmonary embolism: a diagnostic challenge.
|
Thromb Haemost
|
2007
|
0.76
|
125
|
Comparison of 4- and 64-slice CT scanning in the diagnosis of pulmonary embolism.
|
Thromb Haemost
|
2009
|
0.76
|
126
|
Protein S type III deficiency is no risk factor for venous and arterial thromboembolism in 168 thrombophilic families: a retrospective study.
|
Blood Coagul Fibrinolysis
|
2005
|
0.76
|
127
|
Contra: "Antidotes for novel anticoagulants?"--Do we really need them.
|
Thromb Haemost
|
2012
|
0.76
|
128
|
A rebuttal: Counseling pregnant women with factor V Leiden homozygosity: use absolute instead of relative risks.
|
Thromb Haemost
|
2002
|
0.76
|
129
|
Unselected women with elevated levels of factor VIII:C or homocysteine are not at increased risk for obstetric complications.
|
Thromb Haemost
|
2004
|
0.76
|
130
|
Chlamydial LPS antibodies, intima-media thickness and ischemic events in patients with established atherosclerosis.
|
Atherosclerosis
|
2003
|
0.76
|
131
|
The risk of venous thrombosis after air travel: contribution of clinical risk factors.
|
Br J Haematol
|
2014
|
0.76
|
132
|
The role of activated protein C in cancer progression.
|
Thromb Res
|
2010
|
0.76
|
133
|
The performance of two rapid quantitative D-dimer assays in 287 patients with clinically suspected pulmonary embolism.
|
Thromb Res
|
2002
|
0.76
|
134
|
Duration of warfarin in pulmonary embolism.
|
Chest
|
2006
|
0.75
|
135
|
When do we need what evidence?
|
J Clin Epidemiol
|
2003
|
0.75
|
136
|
Could D-dimer provide a definitive diagnosis in patients with suspected pulmonary embolism?
|
Nat Clin Pract Cardiovasc Med
|
2006
|
0.75
|
137
|
Low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism.
|
N Engl J Med
|
2003
|
0.75
|
138
|
Edoxaban versus warfarin for venous thromboembolism.
|
N Engl J Med
|
2014
|
0.75
|
139
|
Excluding pulmonary embolism in primary care using the Wells-rule in combination with a point-of care D-dimer test: a scenario analysis.
|
BMC Fam Pract
|
2010
|
0.75
|
140
|
The additional value of the CRP test in patients in whom the primary care physician excluded pulmonary embolism.
|
Eur J Gen Pract
|
2013
|
0.75
|
141
|
Risk of major bleeding in patients with venous thromboembolism treated with rivaroxaban or with heparin and vitamin K antagonists.
|
Thromb Haemost
|
2015
|
0.75
|
142
|
Clinical impact of major bleeding in patients with venous thromboembolism treated with factor Xa inhibitors or vitamin K antagonists. An individual patient data meta-analysis.
|
Thromb Haemost
|
2017
|
0.75
|
143
|
Non-selective vs. selective beta-blocker treatment and the risk of thrombo-embolic events in patients with heart failure.
|
Eur J Heart Fail
|
2010
|
0.75
|
144
|
Prolactin and venous thrombosis: indications for a novel risk factor?
|
Arterioscler Thromb Vasc Biol
|
2010
|
0.75
|
145
|
Pulmonary embolism as a first clinical sign of occult malignancy: a prospective follow-up study.
|
Thromb Haemost
|
2006
|
0.75
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Thromb Res
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J Am Coll Cardiol
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Pathophysiol Haemost Thromb
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Haematologica
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