Published in Lancet on March 09, 2002
Anti-Xa activity after subcutaneous administration of dalteparin in ICU patients with and without subcutaneous oedema: a pilot study. Crit Care (2006) 1.22
Enoxaparin, effective dosage for intensive care patients: double-blinded, randomised clinical trial. Crit Care (2010) 1.17
Reducing medication errors in critical care: a multimodal approach. Clin Pharmacol (2014) 0.92
A comparative study of varying doses of enoxaparin for thromboprophylaxis in critically ill patients: a double-blinded, randomised controlled trial. Crit Care (2013) 0.88
Antifactor Xa activity in critically ill patients receiving antithrombotic prophylaxis with standard dosages of certoparin: a prospective, clinical study. Crit Care (2005) 0.86
Thromboprophylaxis patterns and determinants in critically ill patients: a multicenter audit. Crit Care (2014) 0.83
Hemostasis during low molecular weight heparin anticoagulation for continuous venovenous hemofiltration: a randomized cross-over trial comparing two hemofiltration rates. Crit Care (2009) 0.83
The Anti-Factor Xa Range For Low Molecular Weight Heparin Thromboprophylaxis. Hematol Rep (2015) 0.79
Venous thromboembolism in the ICU: main characteristics, diagnosis and thromboprophylaxis. Crit Care (2015) 0.78
Bioactivity of enoxaparin in critically ill patients with normal renal function. Br J Clin Pharmacol (2012) 0.76
Measuring the anticoagulant effect of low molecular weight heparins in the critically ill. Crit Care (2006) 0.75
Antifactor Xa levels in critically ill Korean patients receiving enoxaparin for thromboprophylaxis: a prospective observational study. J Korean Med Sci (2013) 0.75
Adequate thromboprophylaxis in critically ill patients. Crit Care (2010) 0.75
Association between aspirin use and deep venous thrombosis in mechanically ventilated ICU patients. J Thromb Thrombolysis (2017) 0.75
Deep vein thrombosis in medical and surgical Intensive Care Unit patients in a Tertiary Care Centre in North India: Incidence and risk factors. J Anaesthesiol Clin Pharmacol (2017) 0.75
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. N Engl J Med (2012) 11.86
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med (2013) 7.76
Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation (2011) 6.47
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet (2007) 5.41
Aspirin plus heparin or aspirin alone in women with recurrent miscarriage. N Engl J Med (2010) 5.06
Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data. Lancet (2011) 4.78
Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA (2006) 4.75
Prevention and treatment of major blood loss. N Engl J Med (2007) 4.72
Rivaroxaban for thromboprophylaxis in acutely ill medical patients. N Engl J Med (2013) 4.43
Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation. Crit Care Med (2004) 3.89
Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial. JAMA (2004) 3.55
Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis. J Trauma (2008) 3.40
Evaluation of short-term consequences of hypoglycemia in an intensive care unit. Crit Care Med (2006) 3.13
Bidirectional relation between inflammation and coagulation. Circulation (2004) 3.00
Association Between Arterial Hyperoxia and Outcome in Subsets of Critical Illness: A Systematic Review, Meta-Analysis, and Meta-Regression of Cohort Studies. Crit Care Med (2015) 2.96
Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial. Lancet (2003) 2.86
2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol (2010) 2.75
Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med (2006) 2.75
Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review. Crit Care (2008) 2.74
The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: a meta-analysis. J Am Coll Cardiol (2003) 2.71
A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Crit Care Med (2013) 2.68
Temporal abstraction for feature extraction: a comparative case study in prediction from intensive care monitoring data. Artif Intell Med (2007) 2.66
Dose-finding and pharmacokinetic study of cisplatin, gemcitabine, and SU5416 in patients with solid tumors. J Clin Oncol (2002) 2.55
Stent thrombosis is associated with an impaired response to antiplatelet therapy. J Am Coll Cardiol (2005) 2.47
Activation of inflammation and coagulation after infusion of C-reactive protein in humans. Circ Res (2005) 2.46
Inflammation, endothelium, and coagulation in sepsis. J Leukoc Biol (2007) 2.46
Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ (2012) 2.38
Comparing the diagnostic performance of 2 clinical decision rules to rule out deep vein thrombosis in primary care patients. Ann Fam Med (2011) 2.34
Diagnostic strategies for excluding pulmonary embolism in clinical outcome studies. A systematic review. Ann Intern Med (2003) 2.33
The incidence of recurrent venous thromboembolism after treatment with vitamin K antagonists in relation to time since first event: a meta-analysis. Arch Intern Med (2003) 2.33
The effect of low molecular weight heparin on survival in patients with advanced malignancy. J Clin Oncol (2005) 2.31
Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort study. Ann Intern Med (2011) 2.28
Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury. Anesthesiology (2006) 2.19
Preoperative or postoperative start of prophylaxis for venous thromboembolism with low-molecular-weight heparin in elective hip surgery? Arch Intern Med (2002) 2.16
Direct thrombin inhibitors. N Engl J Med (2005) 2.15
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk. Blood (2010) 2.14
A comparison of the performance of a model based on administrative data and a model based on clinical data: effect of severity of illness on standardized mortality ratios of intensive care units. Crit Care Med (2012) 2.13
Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure. Crit Care Med (2005) 2.12
Risk of deep vein thrombosis and pulmonary embolism in asthma. Eur Respir J (2012) 2.08
Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood (2008) 2.03
Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo. Diabetes (2006) 1.97
Association between thrombotic microangiopathy and reduced ADAMTS13 activity in malignant hypertension. Hypertension (2008) 1.95
Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1. Circ Res (2006) 1.95
Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism. Arch Intern Med (2004) 1.92
Management of adult Jehovah's Witness patients with acute bleeding. Am J Med (2009) 1.89
Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood (2007) 1.86
Efficacy and safety of recombinant factor VIIa for treatment of severe bleeding: a systematic review. Crit Care Med (2005) 1.82
Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia. Crit Care Med (2006) 1.82
Use of a clinical decision rule in combination with D-dimer concentration in diagnostic workup of patients with suspected pulmonary embolism: a prospective management study. Arch Intern Med (2002) 1.81
Clinicians' response to hyperoxia in ventilated patients in a Dutch ICU depends on the level of FiO2. Intensive Care Med (2010) 1.77
Cardiac output response to norepinephrine in postoperative cardiac surgery patients: interpretation with venous return and cardiac function curves. Crit Care Med (2013) 1.73
Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model. Anesthesiology (2010) 1.72
New fundamentals in hemostasis. Physiol Rev (2013) 1.70
Struggle for implementation of new strategies in intensive care medicine: anticoagulation, insulin, and lower tidal volumes. J Crit Care (2005) 1.66
Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment. Intensive Care Med (2011) 1.65
Thrombotic risk during oral contraceptive use and pregnancy in women with factor V Leiden or prothrombin mutation: a rational approach to contraception. Blood (2011) 1.63
Quality of data collected for severity of illness scores in the Dutch National Intensive Care Evaluation (NICE) registry. Intensive Care Med (2002) 1.63
The impact of different prognostic models and their customization on institutional comparison of intensive care units. Crit Care Med (2007) 1.62
Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women. Arterioscler Thromb Vasc Biol (2006) 1.62
Prediction of long-term mortality in ICU patients: model validation and assessing the effect of using in-hospital versus long-term mortality on benchmarking. Intensive Care Med (2013) 1.61
Time course of platelet counts in critically ill patients. Crit Care Med (2002) 1.60
Widespread transfer of resistance genes between bacterial species in an intensive care unit: implications for hospital epidemiology. J Clin Microbiol (2005) 1.60
Mortality after hospital discharge in ICU patients. Crit Care Med (2013) 1.60
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. Crit Care Med (2008) 1.58
Statin treatment and the risk of recurrent pulmonary embolism. Eur Heart J (2013) 1.58
Transfusion of fresh-frozen plasma in critically ill patients with a coagulopathy before invasive procedures: a randomized clinical trial (CME). Transfusion (2014) 1.58
Cardiovascular risk assessment in haemophilia patients. Thromb Haemost (2010) 1.57
Activation of coagulation and inhibition of fibrinolysis in the human lung on bronchial instillation of lipoteichoic acid and lipopolysaccharide. Crit Care Med (2009) 1.55
Use of oral glucocorticoids and the risk of pulmonary embolism: a population-based case-control study. Chest (2013) 1.55
Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma. J Trauma (2011) 1.54
Determinants of mortality after hospital discharge in ICU patients: literature review and Dutch cohort study. Crit Care Med (2013) 1.54
Outcomes Associated With the Nationwide Introduction of Rapid Response Systems in The Netherlands. Crit Care Med (2015) 1.53
Validity and clinical utility of the simplified Wells rule for assessing clinical probability for the exclusion of pulmonary embolism. Thromb Haemost (2009) 1.51
Risk profile and clinical outcome of symptomatic subsegmental acute pulmonary embolism. Blood (2013) 1.51
Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A. Circulation (2010) 1.50
Thrombosis prophylaxis in patient populations with a central venous catheter: a systematic review. Arch Intern Med (2003) 1.49
Effectiveness and Clinical Outcomes of a Two-Step Implementation of Conservative Oxygenation Targets in Critically Ill Patients: A Before and After Trial. Crit Care Med (2016) 1.47
Salivating for knowledge: potential pharmacological agents in tick saliva. PLoS Med (2008) 1.46
Time-course of cytokines during delirium in elderly patients with hip fractures. J Am Geriatr Soc (2008) 1.45
A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset. Crit Care (2008) 1.44
Dobutamine does not influence inflammatory pathways during human endotoxemia. Crit Care Med (2006) 1.44
How nurses and physicians judge their own quality of care for deteriorating patients on medical wards: self-assessment of quality of care is suboptimal*. Crit Care Med (2012) 1.43
Questionnaires on Family Satisfaction in the Adult ICU: A Systematic Review Including Psychometric Properties. Crit Care Med (2015) 1.43
The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study. Crit Care (2007) 1.43
Influence of entry criteria on mortality risk and number of eligible patients in recent studies on severe sepsis. Crit Care Med (2005) 1.43
Cytokines and acute phase response in delirium. J Psychosom Res (2007) 1.42
Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing, and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study. Ann Intern Med (2014) 1.42
Endogenous tissue-type plasminogen activator impairs host defense during severe experimental Gram-negative sepsis (melioidosis)*. Crit Care Med (2012) 1.41
Thrombin-activatable fibrinolysis inhibitor in hypothyroidism and hyperthyroxinaemia. Thromb Haemost (2012) 1.40
Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit. J Antimicrob Chemother (2006) 1.40
Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia. J Immunol (2002) 1.39
Performance of risk-adjusted control charts to monitor in-hospital mortality of intensive care unit patients: a simulation study. Crit Care Med (2012) 1.39
Postoperative pro-adrenomedullin levels predict mortality in thoracic surgery patients: comparison with Acute Physiology and Chronic Health Evaluation IV Score*. Crit Care Med (2015) 1.39