|
1
|
Loss of autophagy in the central nervous system causes neurodegeneration in mice.
|
Nature
|
2006
|
21.40
|
|
2
|
Guidelines for the use and interpretation of assays for monitoring autophagy.
|
Autophagy
|
2012
|
20.08
|
|
3
|
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
|
Cell
|
2007
|
14.63
|
|
4
|
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice.
|
Science
|
2004
|
6.07
|
|
5
|
Identification of Tim4 as a phosphatidylserine receptor.
|
Nature
|
2007
|
6.06
|
|
6
|
RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.
|
Proc Natl Acad Sci U S A
|
2002
|
2.79
|
|
7
|
Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells.
|
Nature
|
2005
|
2.45
|
|
8
|
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
|
Mol Brain
|
2012
|
2.18
|
|
9
|
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
|
EMBO J
|
2009
|
2.17
|
|
10
|
New neurons clear the path of astrocytic processes for their rapid migration in the adult brain.
|
Neuron
|
2010
|
2.12
|
|
11
|
Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.
|
Proc Natl Acad Sci U S A
|
2011
|
2.09
|
|
12
|
The MAP1-LC3 conjugation system is involved in lipid droplet formation.
|
Biochem Biophys Res Commun
|
2009
|
1.77
|
|
13
|
Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.
|
Cell Metab
|
2009
|
1.66
|
|
14
|
Cytoplasmic reactive oxygen species and SOD1 regulate bone mass during mechanical unloading.
|
J Bone Miner Res
|
2013
|
1.51
|
|
15
|
Participation of autophagy in renal ischemia/reperfusion injury.
|
Biochem Biophys Res Commun
|
2008
|
1.46
|
|
16
|
Discovery of a second form of tripartite complex containing gH-gL of human herpesvirus 6 and observations on CD46.
|
J Virol
|
2004
|
1.37
|
|
17
|
GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.
|
Nat Cell Biol
|
2008
|
1.33
|
|
18
|
Autophagy-physiology and pathophysiology.
|
Histochem Cell Biol
|
2008
|
1.31
|
|
19
|
Human herpesvirus-6 induces MVB formation, and virus egress occurs by an exosomal release pathway.
|
Traffic
|
2008
|
1.31
|
|
20
|
Free fatty acids stimulate autophagy in pancreatic β-cells via JNK pathway.
|
Biochem Biophys Res Commun
|
2010
|
1.21
|
|
21
|
Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase.
|
J Neurosci
|
2004
|
1.21
|
|
22
|
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis.
|
Genes Cells
|
2002
|
1.20
|
|
23
|
Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.
|
J Clin Invest
|
2014
|
1.19
|
|
24
|
LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation.
|
Biochem Biophys Res Commun
|
2010
|
1.18
|
|
25
|
Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes.
|
Proc Natl Acad Sci U S A
|
2011
|
1.16
|
|
26
|
Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis.
|
J Biol Chem
|
2012
|
1.15
|
|
27
|
Participation of autophagy in the degeneration process of rat hepatocytes after transplantation following prolonged cold preservation.
|
Arch Histol Cytol
|
2005
|
1.14
|
|
28
|
RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis.
|
J Bone Miner Res
|
2006
|
1.14
|
|
29
|
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.
|
J Clin Invest
|
2009
|
1.13
|
|
30
|
Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking.
|
PLoS One
|
2010
|
1.12
|
|
31
|
Autophagic neuron death in neonatal brain ischemia/hypoxia.
|
Autophagy
|
2008
|
1.10
|
|
32
|
Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth.
|
Mol Cell Biol
|
2006
|
1.09
|
|
33
|
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens.
|
FEBS J
|
2007
|
1.08
|
|
34
|
Effects of RNA interference of Atg4B on the limited proteolysis of LC3 in PC12 cells and expression of Atg4B in various rat tissues.
|
Autophagy
|
2006
|
1.04
|
|
35
|
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
|
Sci Signal
|
2012
|
1.01
|
|
36
|
Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.
|
J Biol Chem
|
2012
|
0.98
|
|
37
|
Characterization of Cln3p, the gene product responsible for juvenile neuronal ceroid lipofuscinosis, as a lysosomal integral membrane glycoprotein.
|
J Neurochem
|
2003
|
0.95
|
|
38
|
Human herpesvirus 6 open reading frame U14 protein and cellular p53 interact with each other and are contained in the virion.
|
J Virol
|
2005
|
0.95
|
|
39
|
Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation.
|
Autophagy
|
2009
|
0.94
|
|
40
|
Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.
|
J Neurosci
|
2008
|
0.91
|
|
41
|
Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease.
|
J Gastroenterol
|
2011
|
0.90
|
|
42
|
RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway.
|
J Bone Miner Res
|
2007
|
0.90
|
|
43
|
Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.
|
J Immunol
|
2009
|
0.90
|
|
44
|
Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6.
|
Proc Natl Acad Sci U S A
|
2012
|
0.89
|
|
45
|
Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
|
PLoS One
|
2011
|
0.89
|
|
46
|
Exendin-4 improves β-cell function in autophagy-deficient β-cells.
|
Endocrinology
|
2013
|
0.88
|
|
47
|
Autophagic neuron death.
|
Methods Enzymol
|
2009
|
0.88
|
|
48
|
Generation of a recombinant Oka varicella vaccine expressing mumps virus hemagglutinin-neuraminidase protein as a polyvalent live vaccine.
|
Vaccine
|
2007
|
0.86
|
|
49
|
Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.
|
Histochem Cell Biol
|
2011
|
0.85
|
|
50
|
Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains.
|
J Histochem Cytochem
|
2010
|
0.85
|
|
51
|
Deregulation of pancreas-specific oxidoreductin ERO1β in the pathogenesis of diabetes mellitus.
|
Mol Cell Biol
|
2014
|
0.84
|
|
52
|
Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility.
|
Dev Biol
|
2008
|
0.83
|
|
53
|
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.
|
FEBS Lett
|
2013
|
0.83
|
|
54
|
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.
|
Mol Cell Biol
|
2010
|
0.82
|
|
55
|
Very-high-dose alpha-tocopherol supplementation increases blood pressure and causes possible adverse central nervous system effects in stroke-prone spontaneously hypertensive rats.
|
J Neurosci Res
|
2009
|
0.81
|
|
56
|
Biogenesis and proteolytic processing of lysosomal DNase II.
|
PLoS One
|
2013
|
0.79
|
|
57
|
Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.
|
Am J Pathol
|
2010
|
0.79
|
|
58
|
Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils.
|
Autophagy
|
2015
|
0.79
|
|
59
|
Inefficient phagosome maturation in infant macrophages.
|
Biochem Biophys Res Commun
|
2008
|
0.79
|
|
60
|
Purification, cDNA cloning, and secretory properties of FLRG protein from PC12 cells and the distribution of FLRG mRNA and protein in rat tissues.
|
Arch Histol Cytol
|
2003
|
0.79
|
|
61
|
Nitric oxide-mediated injury of interstitial cells of Cajal and intestinal dysmotility under endotoxemia of mice.
|
Biomed Res
|
2014
|
0.78
|
|
62
|
Proteolytic degradation of glutamate decarboxylase mediates disinhibition of hippocampal CA3 pyramidal cells in cathepsin D-deficient mice.
|
J Neurochem
|
2005
|
0.78
|
|
63
|
Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions.
|
Eur J Cell Biol
|
2012
|
0.78
|
|
64
|
Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.
|
Int J Oncol
|
2013
|
0.76
|
|
65
|
Cathepsin D is specifically inhibited by deoxyribonucleic acids.
|
FEBS Lett
|
2002
|
0.75
|
|
66
|
Development and performance test of a soft x-ray polarimeter and ellipsometer for complete polarization analysis.
|
Rev Sci Instrum
|
2009
|
0.75
|
|
67
|
Development of wavelength-dispersive soft X-ray emission spectrometers for transmission electron microscopes--an introduction of valence electron spectroscopy for transmission electron microscopy.
|
J Electron Microsc (Tokyo)
|
2010
|
0.75
|
|
68
|
A case of multicentric Castleman's disease demonstrating severe eosinophilia and enhanced production of interleukin-5.
|
Eur J Haematol
|
2003
|
0.75
|
|
69
|
Fabrication and evaluation of a wideband multilayer laminar-type holographic grating for use with a soft-x-ray flat-field spectrograph in the region of 1.7 keV.
|
Appl Opt
|
2007
|
0.75
|
|
70
|
Development of a pumping laser system for x-ray laser research.
|
Appl Opt
|
2003
|
0.75
|
|
71
|
Development of multilayer laminar-type diffraction gratings to achieve high diffraction efficiencies in the 1-8 keV energy region.
|
Appl Opt
|
2006
|
0.75
|
|
72
|
Cellular localization and tissue distribution of endogenous DFCP1 protein.
|
Biomed Res
|
2015
|
0.75
|
|
73
|
[Mitral valve repair for mitral regurgitation induced by infective endocarditis complicated with ulcerative colitis; report of a case].
|
Kyobu Geka
|
2014
|
0.75
|
|
74
|
A new grating X-ray spectrometer for 2-4 keV enabling a separate observation of In-Lβ and Sn-Lα emissions of indium tin oxide.
|
Microscopy (Oxf)
|
2013
|
0.75
|
|
75
|
Laminar and blazed type holographic gratings for a versatile soft x-ray spectrograph attached to an electron microscope and their evaluation in the 50-200 eV range.
|
Appl Opt
|
2012
|
0.75
|