Published in Prion on June 14, 2013
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A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions. Proc Natl Acad Sci U S A (2003) 2.94
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Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein. J Neurosci (2011) 1.79
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Species-dependent differences in cofactor utilization for formation of the protease-resistant prion protein in vitro. Biochemistry (2010) 1.68
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Cationic phosphorus-containing dendrimers reduce prion replication both in cell culture and in mice infected with scrapie. J Gen Virol (2004) 0.88
EPR study of the interactions between dendrimers and peptides involved in Alzheimer's and prion diseases. Macromol Biosci (2007) 0.87
Amyloid aggregates of the prion peptide PrP106-126 are destabilised by oxidation and by the action of dendrimers. FEBS Lett (2004) 0.87
The influence of densely organized maltose shells on the biological properties of poly(propylene imine) dendrimers: new effects dependent on hydrogen bonding. Chemistry (2008) 0.83
Influence of surface functionality of poly(propylene imine) dendrimers on protease resistance and propagation of the scrapie prion protein. Biomacromolecules (2010) 0.83
Molecular interactions of dendrimers with amyloid peptides: pH dependence. Biomacromolecules (2006) 0.83
The inhibition of prions through blocking prion conversion by permanently charged branched polyamines of low cytotoxicity. Biomaterials (2010) 0.82
Influence of phosphorus dendrimers on the aggregation of the prion peptide PrP 185-208. Biochem Biophys Res Commun (2007) 0.80
The influence of maltose modified poly(propylene imine) dendrimers on hen egg white lysozyme structure and thermal stability. Colloids Surf B Biointerfaces (2012) 0.80
Phosphorus dendrimers affect Alzheimer's (Aβ1-28) peptide and MAP-Tau protein aggregation. Mol Pharm (2012) 0.79
Influence of surface groups on poly(propylene imine) dendrimers antiprion activity. Biomacromolecules (2012) 0.78
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). PLoS One (2013) 0.78
Differentiating prion strains using dendrimers. Adv Healthc Mater (2012) 0.77
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J Biol Chem (2009) 2.64
The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases. EMBO J (2008) 2.43
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Mol Cell (2013) 2.12
The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication. EMBO J (2011) 1.80
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. J Neurosci (2007) 1.54
Genes contributing to prion pathogenesis. J Gen Virol (2008) 1.51
Pathogenic mutations inactivate parkin by distinct mechanisms. J Neurochem (2005) 1.38
Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones. J Biol Chem (2003) 1.27
Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP. Mol Biol Cell (2006) 1.25
Stress-protective signalling of prion protein is corrupted by scrapie prions. EMBO J (2008) 1.18
Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci (2012) 1.15
Aberrant folding of pathogenic Parkin mutants: aggregation versus degradation. J Biol Chem (2008) 1.07
The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein. J Biol Chem (2010) 1.06
Pathogenic mutations located in the hydrophobic core of the prion protein interfere with folding and attachment of the glycosylphosphatidylinositol anchor. J Biol Chem (2004) 1.05
Inhibition of complex glycosylation increases the formation of PrPsc. Traffic (2003) 1.05
Green tea extracts interfere with the stress-protective activity of PrP and the formation of PrP. J Neurochem (2008) 1.04
Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets. J Virol (2005) 0.97
The C-terminal globular domain of the prion protein is necessary and sufficient for import into the endoplasmic reticulum. J Biol Chem (2003) 0.97
Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration. J Clin Invest (2015) 0.95
A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA. J Biomol Screen (2006) 0.93
Helium-oxygen therapy for pediatric acute severe asthma requiring mechanical ventilation. Pediatr Crit Care Med (2003) 0.92
Selective targeting of green fluorescent nanodiamond conjugates to mitochondria in HeLa cells. J Biophotonics (2009) 0.92
Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor. Biochem Biophys Res Commun (2006) 0.92
Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation. Traffic (2004) 0.90
Conserved stress-protective activity between prion protein and Shadoo. J Biol Chem (2011) 0.90
Structural instability of the prion protein upon M205S/R mutations revealed by molecular dynamics simulations. Biophys J (2006) 0.88
A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein. J Biol Chem (2004) 0.87
Synthetic bio-nanoreactor: mechanical and chemical control of polymersome membrane permeability. Angew Chem Int Ed Engl (2012) 0.87
Prion disease: a tale of folds and strains. Brain Pathol (2013) 0.86
Post-translational import of the prion protein into the endoplasmic reticulum interferes with cell viability: a critical role for the putative transmembrane domain. J Biol Chem (2003) 0.85
Targeting of the prion protein to the cytosol: mechanisms and consequences. Curr Issues Mol Biol (2009) 0.84
alpha-Helical domains promote translocation of intrinsically disordered polypeptides into the endoplasmic reticulum. J Biol Chem (2009) 0.84
The influence of densely organized maltose shells on the biological properties of poly(propylene imine) dendrimers: new effects dependent on hydrogen bonding. Chemistry (2008) 0.83
Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes. J Control Release (2010) 0.83
Neuroprotective and neurotoxic signaling by the prion protein. Top Curr Chem (2011) 0.83
Influence of surface functionality of poly(propylene imine) dendrimers on protease resistance and propagation of the scrapie prion protein. Biomacromolecules (2010) 0.83
Parkin is protective against proteotoxic stress in a transgenic zebrafish model. PLoS One (2010) 0.82
Semisynthetic murine prion protein equipped with a GPI anchor mimic incorporates into cellular membranes. Chem Biol (2007) 0.81
Observing fibrillar assemblies on scrapie-infected cells. Pflugers Arch (2008) 0.81
The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of alpha-linked polyglucose. Biol Chem (2005) 0.81
Cross-linked polymersomes as nanoreactors for controlled and stabilized single and cascade enzymatic reactions. Nanoscale (2014) 0.81
Cast adhesive polyelectrolyte complex particle films of unmodified or maltose-modified poly(ethyleneimine) and cellulose sulphate: fabrication, film stability and retarded release of zoledronate. Biointerphases (2013) 0.81
The influence of maltose modified poly(propylene imine) dendrimers on hen egg white lysozyme structure and thermal stability. Colloids Surf B Biointerfaces (2012) 0.80
The α-helical structure of prodomains promotes translocation of intrinsically disordered neuropeptide hormones into the endoplasmic reticulum. J Biol Chem (2013) 0.79
Functionalization of solid surfaces with hyperbranched polyesters to control protein adsorption. Colloids Surf B Biointerfaces (2008) 0.79
Cellular prion protein mediates toxic signaling of amyloid beta. Neurodegener Dis (2011) 0.78
Influence of surface groups on poly(propylene imine) dendrimers antiprion activity. Biomacromolecules (2012) 0.78
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). PLoS One (2013) 0.78
Protein immobilization on liposomes and lipid-coated nanoparticles by protein trans-splicing. J Pept Sci (2010) 0.78
Photo-crosslinked and pH sensitive polymersomes for triggering the loading and release of cargo. Chem Commun (Camb) (2011) 0.78
Structural features within the nascent chain regulate alternative targeting of secretory proteins to mitochondria. EMBO J (2013) 0.78
Dense shell glycodendrimers as potential nontoxic anti-amyloidogenic agents in Alzheimer's disease. Amyloid-dendrimer aggregates morphology and cell toxicity. Biomacromolecules (2011) 0.77
Biocompatibility and efficacy of oligomaltose-grafted poly(ethylene imine)s (OM-PEIs) for in vivo gene delivery. Mol Pharm (2013) 0.77
Tailored synthesis of intelligent polymer nanocapsules: an investigation of controlled permeability and pH-dependent degradability. ACS Nano (2012) 0.77
Differentiating prion strains using dendrimers. Adv Healthc Mater (2012) 0.77
Cellular interactions with photo-cross-linked and pH-sensitive polymersomes: biocompatibility and uptake studies. Biomacromolecules (2012) 0.76
Poly(propylene imine) dendrimers modified with maltose or maltotriose protect phosphorothioate oligodeoxynucleotides against nuclease activity. Biochem Biophys Res Commun (2012) 0.76
pH-dependent release of doxorubicin from fast photo-cross-linkable polymersomes based on benzophenone units. Chemistry (2012) 0.76
In vivo toxicity of poly(propyleneimine) dendrimers. J Biomed Mater Res A (2011) 0.76
Conditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides. J Biol Chem (2010) 0.76
The influence of maltotriose-modified poly(propylene imine) dendrimers on the chronic lymphocytic leukemia cells in vitro: dense shell G4 PPI. Mol Pharm (2013) 0.76
Synthesis of hetero-polymer functionalized nanocarriers by combining surface-initiated ATRP and RAFT polymerization. Small (2012) 0.76
The heat shock response is modulated by and interferes with toxic effects of scrapie prion protein and amyloid β. J Biol Chem (2012) 0.75
Influence of fourth generation poly(propyleneimine) dendrimers on blood cells. J Biomed Mater Res A (2012) 0.75
Sweet Polymers: Poly(2-ethyl-2-oxazoline) Glycopolymers by Reductive Amination. Biomacromolecules (2016) 0.75
An alternative route to dye-polymer complexation study using asymmetrical flow field-flow fractionation. J Chromatogr A (2010) 0.75
Combined EPR and molecular modeling study of PPI dendrimers interacting with copper ions: effect of generation and maltose decoration. J Phys Chem B (2014) 0.75
Prion proteins. Top Curr Chem (2011) 0.75
Reversed hexagonal lyotropic liquid-crystal and open-shell glycodendrimers as potential vehicles for sustained release of sodium diclofenac. J Phys Chem B (2014) 0.75
Cross-linked and pH sensitive supported polymer bilayers from polymersomes - studies concerning thickness, rigidity and fluidity. Soft Matter (2014) 0.75
The prion protein: friend and foe. Curr Issues Mol Biol (2009) 0.75
Modulation of biogenic amines content by poly(propylene imine) dendrimers in rats. J Physiol Biochem (2012) 0.75
Ni(II)-NTA modified poly(ethylene imine) glycopolymers: physicochemical properties and first in vitro study of polyplexes formed with HIV-derived peptides. Macromol Biosci (2013) 0.75
Investigation of dye glycopolymer and glycopolymer hydrogel interactions for development of multi-release system. J Control Release (2010) 0.75
Sugar-decorated dendritic nanocarriers: encapsulation and release of the octahedral rhenium cluster complex [Re6S8(OH)6]4-. Chem Asian J (2010) 0.75
Synthesis of a GPI anchor module suitable for protein post-translational modification. Biopolymers (2010) 0.75
Hybrid nanoalloy: nanofibers fabricated by self-assembling dendrimers mediate in situ CdSe quantum dots and their metallization with discrete gold nanoparticles. Adv Mater (2011) 0.75
Genotoxicity of poly(propylene imine) dendrimers. Biopolymers (2012) 0.75
Stability of dendriplexes formed by anti-HIV genetic material and poly(propylene imine) dendrimers in the presence of glucosaminoglycans. J Phys Chem B (2012) 0.75
Stick-slip of the three-phase line in measurements of dynamic contact angles. Langmuir (2006) 0.75
Glycodendrimer PPI as a Potential Drug in Chronic Lymphocytic Leukaemia. The Influence of Glycodendrimer on Apoptosis in In Vitro B-CLL Cells Defined by Microarrays. Anticancer Agents Med Chem (2017) 0.75
Supramolecular glycodendrimer-based hybrid drugs. Biomacromolecules (2014) 0.75
Cation-induced unidirectional self-assembly of amino-terminated poly(propylene imine) dendrimers. Small (2010) 0.75
Supracolloidal multivalent interactions and wrapping of dendronized glycopolymers on native cellulose nanocrystals. J Am Chem Soc (2014) 0.75
In situ ATR-FTIR investigation on the preparation and enantiospecificity of chiral polyelectrolyte multilayers. ACS Appl Mater Interfaces (2009) 0.75
Fabricating pH-stable and swellable very thin hyperbranched poly(ethylene imine)-oligosaccharide films fabricated without precoating: first view on protein adsorption. Macromol Rapid Commun (2012) 0.75
Oligosaccharide shells as a decisive factor for moderate and strong ionic interactions of dendritic poly(ethylene imine) scaffolds under shear forces. Chemistry (2014) 0.75