Published in Am J Physiol Heart Circ Physiol on June 21, 2013
Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation. Proc Natl Acad Sci U S A (2013) 1.02
Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats. PLoS One (2016) 0.76
MassBank: a public repository for sharing mass spectral data for life sciences. J Mass Spectrom (2010) 6.16
Multiple high-throughput analyses monitor the response of E. coli to perturbations. Science (2007) 5.87
Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell (2010) 4.90
Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature (2002) 3.60
Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. Cancer Res (2009) 3.50
ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat Med (2002) 3.36
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell (2011) 3.00
Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell (2013) 2.58
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med (2002) 2.37
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain (2012) 2.18
Autophagy protects the proximal tubule from degeneration and acute ischemic injury. J Am Soc Nephrol (2011) 2.04
Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics (2009) 2.03
Oncometabolites: linking altered metabolism with cancer. J Clin Invest (2013) 1.78
SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. J Am Soc Nephrol (2009) 1.70
MathDAMP: a package for differential analysis of metabolite profiles. BMC Bioinformatics (2006) 1.68
Analysis of liver metabolism in a rat model of heart failure. Int J Cardiol (2011) 1.68
Visualization of three-way comparisons of omics data. BMC Bioinformatics (2007) 1.66
HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice. J Hepatol (2011) 1.64
Simultaneous determination of the main metabolites in rice leaves using capillary electrophoresis mass spectrometry and capillary electrophoresis diode array detection. Plant J (2004) 1.63
Measurement of internal body time by blood metabolomics. Proc Natl Acad Sci U S A (2009) 1.56
Metabolome analysis by capillary electrophoresis-mass spectrometry. J Chromatogr A (2007) 1.53
Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism. Mol Syst Biol (2009) 1.52
DNA microarray profiling identified a new role of growth hormone in vascular remodeling of rat ductus arteriosus. J Physiol Sci (2011) 1.49
Caveolin gene transfer improves glucose metabolism in diabetic mice. Am J Physiol Cell Physiol (2009) 1.45
A systematic survey of in vivo obligate chaperonin-dependent substrates. EMBO J (2010) 1.41
Depiction of metabolome changes in histidine-starved Escherichia coli by CE-TOFMS. Mol Biosyst (2007) 1.41
Lipopolysaccharide Delays Closure of the Rat Ductus Arteriosus by Induction of Inducible Nitric Oxide Synthase But Not Prostaglandin E2. Circ J (2016) 1.39
Human blood metabolite timetable indicates internal body time. Proc Natl Acad Sci U S A (2012) 1.37
Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure. Circ Heart Fail (2010) 1.35
Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration. J Biol Chem (2004) 1.31
Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis. Curr Bioinform (2012) 1.31
Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease. J Hepatol (2011) 1.30
Cystathionine beta-synthase as a carbon monoxide-sensitive regulator of bile excretion. Hepatology (2009) 1.29
Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest (2006) 1.29
mTORC1 is essential for leukemia propagation but not stem cell self-renewal. J Clin Invest (2012) 1.27
Metabolomic profiling of uremic solutes in CKD patients. Hypertens Res (2010) 1.26
Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia. Mol Biosyst (2011) 1.24
Roles of hemoglobin Allostery in hypoxia-induced metabolic alterations in erythrocytes: simulation and its verification by metabolome analysis. J Biol Chem (2007) 1.24
Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. Am J Physiol Heart Circ Physiol (2007) 1.23
Metabolomic profiling of lung and prostate tumor tissues by capillary electrophoresis time-of-flight mass spectrometry. Metabolomics (2012) 1.17
Metabolomics approach for enzyme discovery. J Proteome Res (2006) 1.16
Carbon monoxide from heme oxygenase-2 Is a tonic regulator against NO-dependent vasodilatation in the adult rat cerebral microcirculation. Circ Res (2005) 1.16
Hyaluronan constitutively regulates activation of COX-2-mediated cell survival activity in intestinal epithelial and colon carcinoma cells. J Biol Chem (2008) 1.13
Gene transfection of H25A mutant heme oxygenase-1 protects cells against hydroperoxide-induced cytotoxicity. J Biol Chem (2002) 1.13
Methamphetamine in Japan: the consequences of methamphetamine abuse as a function of route of administration. Addiction (2002) 1.11
Hepatitis C virus infection promotes hepatic gluconeogenesis through an NS5A-mediated, FoxO1-dependent pathway. J Virol (2011) 1.09
Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol (2005) 1.08
Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency. Cell Rep (2013) 1.08
The emerging role of fumarate as an oncometabolite. Front Oncol (2012) 1.08
Insulin resistance in skeletal muscles of caveolin-3-null mice. Proc Natl Acad Sci U S A (2004) 1.07
Multiple transcripts of Ca2+ channel alpha1-subunits and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus. Am J Physiol Heart Circ Physiol (2005) 1.07
Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration. Am J Physiol Heart Circ Physiol (2008) 1.06
13C-metabolic flux analysis for batch culture of Escherichia coli and its Pyk and Pgi gene knockout mutants based on mass isotopomer distribution of intracellular metabolites. Biotechnol Prog (2010) 1.06
Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice. J Biol Chem (2004) 1.05
Prediction of liquid chromatographic retention times of peptides generated by protease digestion of the Escherichia coli proteome using artificial neural networks. J Proteome Res (2006) 1.03
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation. Tumour Biol (2014) 1.02
Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli. J Biol Chem (2009) 1.00
Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiac hypertrophy in chronic angiotensin II-infused mice. Hypertension (2010) 0.99
von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development (2010) 0.99
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia. Cell Rep (2013) 0.99
Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43). J Biol Chem (2009) 0.98
T-type Ca2+ channels promote oxygenation-induced closure of the rat ductus arteriosus not only by vasoconstriction but also by neointima formation. J Biol Chem (2009) 0.98
HIF-1alpha is necessary to support gluconeogenesis during liver regeneration. Biochem Biophys Res Commun (2009) 0.98
Time-resolved metabolomics reveals metabolic modulation in rice foliage. BMC Syst Biol (2008) 0.97
From O2 to H2S: a landscape view of gas biology. Keio J Med (2002) 0.97
Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. Ann Bot (2006) 0.97
Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis. PLoS Pathog (2012) 0.96
Leydig cell-derived heme oxygenase-1 regulates apoptosis of premeiotic germ cells in response to stress. J Clin Invest (2002) 0.96
In silico modeling and metabolome analysis of long-stored erythrocytes to improve blood storage methods. J Biotechnol (2009) 0.96
Gene knockout and metabolome analysis of carnitine/organic cation transporter OCTN1. Pharm Res (2010) 0.95
Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy. J Mol Cell Cardiol (2013) 0.95
Degradation of ppGpp by nudix pyrophosphatase modulates the transition of growth phase in the bacterium Thermus thermophilus. J Biol Chem (2009) 0.94
Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy. Anal Bioanal Chem (2012) 0.94
Mechanical stress-dependent transcriptional regulation of sarcolipin gene in the rodent atrium. Biochem Biophys Res Commun (2005) 0.94
Dynamic regulation of Th17 differentiation by oxygen concentrations. Int Immunol (2011) 0.93
Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A. J Biol Chem (2008) 0.93
Inhibition of EP4 signaling attenuates aortic aneurysm formation. PLoS One (2012) 0.93
Intrarenal suppression of angiotensin II type 1 receptor binding molecule in angiotensin II-infused mice. Am J Physiol Renal Physiol (2010) 0.92
Two atypical L-cysteine-regulated NADPH-dependent oxidoreductases involved in redox maintenance, L-cystine and iron reduction, and metronidazole activation in the enteric protozoan Entamoeba histolytica. J Biol Chem (2010) 0.92
Acupuncture ameliorated skeletal muscle atrophy induced by hindlimb suspension in mice. Biochem Biophys Res Commun (2011) 0.91
Sarcalumenin alleviates stress-induced cardiac dysfunction by improving Ca2+ handling of the sarcoplasmic reticulum. Cardiovasc Res (2007) 0.91
Capillary electrophoresis-mass spectrometry-based metabolome analysis of serum and saliva from neurodegenerative dementia patients. Electrophoresis (2013) 0.91
Caveolin-3 inhibits growth signal in cardiac myoblasts in a Ca2+-dependent manner. J Cell Mol Med (2006) 0.90
Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal. Am J Physiol Cell Physiol (2007) 0.90
Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role. Am J Physiol Heart Circ Physiol (2002) 0.90
The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner. Dev Biol (2011) 0.90
L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease. J Hypertens (2012) 0.90
Metabolic and morphological changes of an oil accumulating trebouxiophycean alga in nitrogen-deficient conditions. Metabolomics (2012) 0.89
Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells. Int J Cancer (2013) 0.88
Autophagy protects kidney proximal tubule epithelial cells from mitochondrial metabolic stress. Autophagy (2013) 0.88