VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 23794399)

Published in Mol Carcinog on June 21, 2013

Authors

Martha L Slattery1, Abbie Lundgreen, Roger K Wolff

Author Affiliations

1: Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah.

Articles citing this

A Candidate-Pathway Approach to Identify Gene-Environment Interactions: Analyses of Colon Cancer Risk and Survival. J Natl Cancer Inst (2015) 0.86

A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer. Carcinogenesis (2014) 0.81

Angiogenesis genotyping and clinical outcome during regorafenib treatment in metastatic colorectal cancer patients. Sci Rep (2016) 0.79

Polymorphisms of VEGF and VEGF receptors are associated with the occurrence of ovarian hyperstimulation syndrome (OHSS)-a retrospective case-control study. J Ovarian Res (2014) 0.77

The influence of the CHIEF pathway on colorectal cancer-specific mortality. PLoS One (2014) 0.77

The Effect of FLT1 Variant on Long-Term Cardiovascular Outcomes: Validation of a Locus Identified in a Previous Genome-Wide Association Study. PLoS One (2016) 0.75

No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients. Cancer Med (2016) 0.75

A novel kinase mutation in VEGFR-1 predisposes its αC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation. Eur J Hum Genet (2016) 0.75

FLT-1 gene polymorphisms and protein expression profile in rheumatoid arthritis. PLoS One (2017) 0.75

Association of -460C/T and +405 G/C polymorphisms of vascular endothelial growth factor gene and susceptibility to ovarian hyperstimulation syndrome. Int J Reprod Biomed (Yazd) (2017) 0.75

Cancer Transcriptome Dataset Analysis: Comparing Methods of Pathway and Gene Regulatory Network-Based Cluster Identification. OMICS (2017) 0.75

Articles by these authors

Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology (2005) 6.34

Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers. Cancer Res (2005) 5.68

Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. J Natl Cancer Inst (2006) 3.08

Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer (2007) 2.36

A model to determine colorectal cancer risk using common genetic susceptibility loci. Gastroenterology (2015) 2.14

A comparison of colon and rectal somatic DNA alterations. Dis Colon Rectum (2009) 1.85

APC mutations and other genetic and epigenetic changes in colon cancer. Mol Cancer Res (2007) 1.54

MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype. Genes Chromosomes Cancer (2010) 1.51

Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population. Carcinogenesis (2012) 1.40

Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.37

IL6 genotypes and colon and rectal cancer. Cancer Causes Control (2007) 1.36

Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis (2007) 1.28

Microsatellite instability and survival in rectal cancer. Cancer Causes Control (2009) 1.24

Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. Carcinogenesis (2010) 1.19

Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. Mutat Res (2008) 1.18

Somatic alterations, metabolizing genes and smoking in rectal cancer. Int J Cancer (2009) 1.17

Increased risk of colon cancer associated with a genetic polymorphism of SMAD7. Cancer Res (2010) 1.17

Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. Genes Chromosomes Cancer (2013) 1.16

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol Carcinog (2011) 1.16

Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 1.15

Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. Int J Cancer (2011) 1.12

Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway. Carcinogenesis (2010) 1.11

The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer. Genes Chromosomes Cancer (2008) 1.10

MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progression. Carcinogenesis (2016) 1.08

MAP kinase genes and colon and rectal cancer. Carcinogenesis (2012) 1.08

Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival. Carcinogenesis (2011) 1.05

Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. Mutat Res (2010) 1.04

CDX2 VDR polymorphism and colorectal cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.04

Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. Int J Cancer (2008) 1.04

Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors. Genes Chromosomes Cancer (2009) 1.03

Active and passive smoking, IL6, ESR1, and breast cancer risk. Breast Cancer Res Treat (2007) 1.00

Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. Clin Gastroenterol Hepatol (2006) 1.00

Genetic variation in bone morphogenetic protein and colon and rectal cancer. Int J Cancer (2011) 0.99

Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. BMC Med Genet (2010) 0.99

Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes. Mutat Res (2012) 0.99

Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States. Breast Cancer Res Treat (2011) 0.98

Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci. Cancer Epidemiol Biomarkers Prev (2014) 0.98

Vitamin D receptor gene polymorphisms, dietary promotion of insulin resistance, and colon and rectal cancer. Nutr Cancer (2006) 0.97

Genetic admixture among Hispanics and candidate gene polymorphisms: potential for confounding in a breast cancer study? Cancer Epidemiol Biomarkers Prev (2007) 0.97

Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study. PLoS One (2013) 0.97

Tumor markers and rectal cancer: support for an inflammation-related pathway. Int J Cancer (2009) 0.97

Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer. Cancer Causes Control (2007) 0.95

Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2012) 0.95

Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes. Cancer Causes Control (2010) 0.94

Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2013) 0.93

Angiogenesis genes, dietary oxidative balance and breast cancer risk and progression: the Breast Cancer Health Disparities Study. Int J Cancer (2013) 0.92

Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women. Nutr Cancer (2011) 0.92

Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S. Breast Cancer Res Treat (2011) 0.92

Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. Int J Mol Epidemiol Genet (2012) 0.91

Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk. Cancer Epidemiol Biomarkers Prev (2015) 0.90

Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer. Cancer Epidemiol Biomarkers Prev (2009) 0.90

Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis. J Rheumatol (2013) 0.90

Variation in the CYP19A1 gene and risk of colon and rectal cancer. Cancer Causes Control (2011) 0.89

Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer. Nutr Cancer (2013) 0.89

Interleukin genes and associations with colon and rectal cancer risk and overall survival. Int J Cancer (2012) 0.88

Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer. Cancer (2011) 0.88

TERT's role in colorectal carcinogenesis. Mol Carcinog (2012) 0.86

Genetic variation in the transforming growth factor-β-signaling pathway, lifestyle factors, and risk of colon or rectal cancer. Dis Colon Rectum (2012) 0.86

Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors. Nutr Cancer (2010) 0.86

Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer. PLoS One (2012) 0.86

The influence of genetic ancestry and ethnicity on breast cancer survival associated with genetic variation in the TGF-β-signaling pathway: The Breast Cancer Health Disparities Study. Cancer Causes Control (2013) 0.86

PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: interaction with fatty acids in colon cancer and rectal cancer. Genes Nutr (2012) 0.85

Tumor necrosis factor-related genes and colon and rectal cancer. Int J Mol Epidemiol Genet (2011) 0.85

Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet (2010) 0.85

Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer. Mutat Res (2006) 0.84

SEPP1 influences breast cancer risk among women with greater native american ancestry: the breast cancer health disparities study. PLoS One (2013) 0.84

Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk. Obesity (Silver Spring) (2008) 0.84

Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2014) 0.83

MSH6 G39E polymorphism and CpG island methylator phenotype in colon cancer. Mol Carcinog (2009) 0.82

Alcohol consumption and rectal tumor mutations and epigenetic changes. Dis Colon Rectum (2010) 0.82

Epidermal growth factor receptor (EGFR) polymorphisms and breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. Int J Mol Epidemiol Genet (2013) 0.81

Lack of correlation between in silico projection of function and quantitative real-time PCR-determined gene expression levels in colon tissue. Pharmgenomics Pers Med (2013) 0.81

Leptin and colorectal cancer: an undefined link. Nat Clin Pract Gastroenterol Hepatol (2007) 0.81

Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment. Nutr Cancer (2011) 0.80