Published in PLoS One on May 17, 2012
Systematic review: diet-gene interactions and the risk of colorectal cancer. Aliment Pharmacol Ther (2012) 1.01
Oxidative stress in the pathogenesis of colorectal cancer: cause or consequence? Biomed Res Int (2013) 0.87
Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. Gene (2013) 0.85
Selenium and chronic diseases: a nutritional genomics perspective. Nutrients (2015) 0.84
A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer. Carcinogenesis (2014) 0.81
Friend or foe? The current epidemiologic evidence on selenium and human cancer risk. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2013) 0.81
Genes, environment and gene expression in colon tissue: a pathway approach to determining functionality. Int J Mol Epidemiol Genet (2016) 0.78
The influence of the CHIEF pathway on colorectal cancer-specific mortality. PLoS One (2014) 0.77
Mitochondrial ROS control of cancer. Semin Cancer Biol (2017) 0.75
Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology (2005) 6.34
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. Am J Hum Genet (2007) 6.26
Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level. Cancer Epidemiol Biomarkers Prev (2001) 3.43
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Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions. Biochim Biophys Acta (2009) 2.41
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Physical activity and colorectal cancer. Am J Epidemiol (2003) 2.04
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Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases. J Biol Chem (1999) 1.77
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Mammalian selenium-containing proteins. Annu Rev Nutr (2001) 1.63
Energy balance and rectal cancer: an evaluation of energy intake, energy expenditure, and body mass index. Nutr Cancer (2003) 1.55
Structure-expression relationships of the 15-kDa selenoprotein gene. Possible role of the protein in cancer etiology. J Biol Chem (2000) 1.45
Selenoprotein metabolism and function: evidence for more than one function for selenoprotein P. J Nutr (2003) 1.34
Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol Biomarkers Prev (2008) 1.27
Lifestyle factors and Ki-ras mutations in colon cancer tumors. Mutat Res (2001) 1.19
Diet activity, and lifestyle associations with p53 mutations in colon tumors. Cancer Epidemiol Biomarkers Prev (2002) 1.18
Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells. Cancer Prev Res (Phila) (2010) 1.10
No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue. Biochemistry (2009) 1.09
Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins. Antioxid Redox Signal (2010) 1.09
Genetic variants in selenoprotein genes increase risk of colorectal cancer. Carcinogenesis (2010) 1.07
Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes. Mutat Res (2012) 0.99
High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection program. Cancer Epidemiol Biomarkers Prev (2006) 0.98
Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. Eur Heart J (2011) 0.92
Expression of selenoprotein-coding genes SEPP1, SEP15 and hGPX1 in non-small cell lung cancer. Lung Cancer (2008) 0.88
Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue. Oral Oncol (2011) 0.88
Selenoprotein S expression in reactive astrocytes following brain injury. Glia (2011) 0.87
Transcriptomics and functional genetic polymorphisms as biomarkers of micronutrient function: focus on selenium as an exemplar. Proc Nutr Soc (2011) 0.86
An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling. J Biol Chem (2004) 0.85
Estrogen status alters tissue distribution and metabolism of selenium in female rats. J Nutr Biochem (2011) 0.85
The influence of selenium and selenoprotein gene variants on colorectal cancer risk. Mutagenesis (2012) 0.84
Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion. Biochem Biophys Res Commun (2005) 0.83
Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction. Biochem Pharmacol (2010) 0.81
Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer. Genes Chromosomes Cancer (2012) 0.81
Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology (2005) 6.34
Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers. Cancer Res (2005) 5.68
Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. J Natl Cancer Inst (2006) 3.08
Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer (2007) 2.36
A comparison of colon and rectal somatic DNA alterations. Dis Colon Rectum (2009) 1.85
APC mutations and other genetic and epigenetic changes in colon cancer. Mol Cancer Res (2007) 1.54
MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype. Genes Chromosomes Cancer (2010) 1.51
The persistence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry (2004) 1.46
Genetic variation in genes involved in hormones, inflammation and energetic factors and breast cancer risk in an admixed population. Carcinogenesis (2012) 1.40
Associations between ERalpha, ERbeta, and AR genotypes and colon and rectal cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.37
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5. Protein Sci (2007) 1.36
IL6 genotypes and colon and rectal cancer. Cancer Causes Control (2007) 1.36
Caregiver-recipient closeness and symptom progression in Alzheimer disease. The Cache County Dementia Progression Study. J Gerontol B Psychol Sci Soc Sci (2009) 1.33
Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. Carcinogenesis (2007) 1.28
Microsatellite instability and survival in rectal cancer. Cancer Causes Control (2009) 1.24
Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry (2005) 1.23
Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. Carcinogenesis (2010) 1.19
Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways. Mutat Res (2008) 1.18
Increased risk of colon cancer associated with a genetic polymorphism of SMAD7. Cancer Res (2010) 1.17
Somatic alterations, metabolizing genes and smoking in rectal cancer. Int J Cancer (2009) 1.17
Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. Genes Chromosomes Cancer (2013) 1.16
JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol Carcinog (2011) 1.16
Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 1.15
Toll-like receptor genes and their association with colon and rectal cancer development and prognosis. Int J Cancer (2011) 1.12
Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway. Carcinogenesis (2010) 1.11
Prospective study of Dietary Approaches to Stop Hypertension- and Mediterranean-style dietary patterns and age-related cognitive change: the Cache County Study on Memory, Health and Aging. Am J Clin Nutr (2013) 1.11
Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study. Am J Geriatr Psychiatry (2006) 1.10
The MLH1 -93 G>A promoter polymorphism and genetic and epigenetic alterations in colon cancer. Genes Chromosomes Cancer (2008) 1.10
MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progression. Carcinogenesis (2016) 1.08
MAP kinase genes and colon and rectal cancer. Carcinogenesis (2012) 1.08
Gender differences in the association between religious involvement and depression: the Cache County (Utah) study. J Gerontol B Psychol Sci Soc Sci (2006) 1.06
Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival. Carcinogenesis (2011) 1.05
CDX2 VDR polymorphism and colorectal cancer. Cancer Epidemiol Biomarkers Prev (2007) 1.04
Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. Mutat Res (2010) 1.04
Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. Int J Cancer (2008) 1.04
Measurement of myostatin concentrations in human serum: Circulating concentrations in young and older men and effects of testosterone administration. Mol Cell Endocrinol (2009) 1.03
Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors. Genes Chromosomes Cancer (2009) 1.03
Maternal vitamin B-6 and folate status and risk of oral cleft birth defects in the Philippines. Birth Defects Res A Clin Mol Teratol (2004) 1.03
Active and passive smoking, IL6, ESR1, and breast cancer risk. Breast Cancer Res Treat (2007) 1.00
Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. Clin Gastroenterol Hepatol (2006) 1.00
Plasma zinc concentrations of mothers and the risk of nonsyndromic oral clefts in their children: a case-control study in the Philippines. Birth Defects Res A Clin Mol Teratol (2005) 1.00
Genetic variation in bone morphogenetic protein and colon and rectal cancer. Int J Cancer (2011) 0.99
Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. BMC Med Genet (2010) 0.99
Oxidative balance and colon and rectal cancer: interaction of lifestyle factors and genes. Mutat Res (2012) 0.99
Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States. Breast Cancer Res Treat (2011) 0.98
Vitamin D receptor gene polymorphisms, dietary promotion of insulin resistance, and colon and rectal cancer. Nutr Cancer (2006) 0.97
Predictors of progression to severe Alzheimer's disease in an incidence sample. Alzheimers Dement (2012) 0.97
Genetic admixture among Hispanics and candidate gene polymorphisms: potential for confounding in a breast cancer study? Cancer Epidemiol Biomarkers Prev (2007) 0.97
Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study. PLoS One (2013) 0.97
VEGFA, FLT1, KDR and colorectal cancer: assessment of disease risk, tumor molecular phenotype, and survival. Mol Carcinog (2013) 0.97
Tumor markers and rectal cancer: support for an inflammation-related pathway. Int J Cancer (2009) 0.97
An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition. J Biol Chem (2012) 0.96
Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer. Cancer Causes Control (2007) 0.95
Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2012) 0.95
Diet, physical activity, and body size associations with rectal tumor mutations and epigenetic changes. Cancer Causes Control (2010) 0.94
Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2013) 0.93
Nutrients in folate-mediated, one-carbon metabolism and the risk of rectal tumors in men and women. Nutr Cancer (2011) 0.92
Vitamin D intake, vitamin D receptor polymorphisms, and breast cancer risk among women living in the southwestern U.S. Breast Cancer Res Treat (2011) 0.92
Angiogenesis genes, dietary oxidative balance and breast cancer risk and progression: the Breast Cancer Health Disparities Study. Int J Cancer (2013) 0.92
Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study. Int J Mol Epidemiol Genet (2012) 0.91
Cardiovascular events are not associated with MTHFR polymorphisms, but are associated with methotrexate use and traditional risk factors in US veterans with rheumatoid arthritis. J Rheumatol (2013) 0.90
Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system. Osteoarthritis Cartilage (2004) 0.90
Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer. Cancer Epidemiol Biomarkers Prev (2009) 0.90
Church attendance and new episodes of major depression in a community study of older adults: the Cache County Study. J Gerontol B Psychol Sci Soc Sci (2008) 0.89
Dietary influence on MAPK-signaling pathways and risk of colon and rectal cancer. Nutr Cancer (2013) 0.89
Variation in the CYP19A1 gene and risk of colon and rectal cancer. Cancer Causes Control (2011) 0.89
Interleukin genes and associations with colon and rectal cancer risk and overall survival. Int J Cancer (2012) 0.88
Baseline disability in activities of daily living predicts dementia risk even after controlling for baseline global cognitive ability and depressive symptoms. Int J Geriatr Psychiatry (2012) 0.88
Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer. Cancer (2011) 0.88
Calcium, vitamin D, VDR genotypes, and epigenetic and genetic changes in rectal tumors. Nutr Cancer (2010) 0.86
TERT's role in colorectal carcinogenesis. Mol Carcinog (2012) 0.86
The influence of genetic ancestry and ethnicity on breast cancer survival associated with genetic variation in the TGF-β-signaling pathway: The Breast Cancer Health Disparities Study. Cancer Causes Control (2013) 0.86
Genetic variation in the transforming growth factor-β-signaling pathway, lifestyle factors, and risk of colon or rectal cancer. Dis Colon Rectum (2012) 0.86
Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. Int J Mol Epidemiol Genet (2010) 0.85
Tumor necrosis factor-related genes and colon and rectal cancer. Int J Mol Epidemiol Genet (2011) 0.85