Published in Genes Cells on June 24, 2013
Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature (2009) 4.32
Dominant role of the niche in melanocyte stem-cell fate determination. Nature (2002) 4.05
Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol (2005) 3.55
Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell (2007) 3.26
Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development (2005) 2.98
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A (2011) 2.51
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci U S A (2002) 2.34
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Genes Dev (2008) 2.33
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J Clin Invest (2002) 2.26
Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion. J Clin Invest (2007) 2.20
Local protease signaling contributes to neural tube closure in the mouse embryo. Dev Cell (2010) 2.19
WAVE2 is required for directed cell migration and cardiovascular development. Nature (2003) 2.09
Clinical analysis of paraneoplastic encephalitis associated with ovarian teratoma. J Neurooncol (2007) 2.03
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
PAR1 cleavage and signaling in response to activated protein C and thrombin. J Biol Chem (2005) 1.83
Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets. J Biol Chem (2010) 1.77
Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patches. Immunity (2002) 1.74
A fat body-derived IGF-like peptide regulates postfeeding growth in Drosophila. Dev Cell (2009) 1.69
TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol (2003) 1.66
Olfactory receptor antagonism between odorants. EMBO J (2003) 1.66
CYP306A1, a cytochrome P450 enzyme, is essential for ecdysteroid biosynthesis in the prothoracic glands of Bombyx and Drosophila. J Biol Chem (2004) 1.65
Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm. Blood (2011) 1.61
Molecular characterization of melanocyte stem cells in their niche. Development (2005) 1.53
Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction. FASEB J (2005) 1.51
Odorant response assays for a heterologously expressed olfactory receptor. Biochem Biophys Res Commun (2003) 1.49
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proc Natl Acad Sci U S A (2003) 1.45
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest (2011) 1.44
The unique evolution of neuropeptide genes in the silkworm Bombyx mori. Insect Biochem Mol Biol (2008) 1.42
Neverland is an evolutionally conserved Rieske-domain protein that is essential for ecdysone synthesis and insect growth. Development (2006) 1.41
Involvement of N-terminal-extended form of sphingosine kinase 2 in serum-dependent regulation of cell proliferation and apoptosis. J Biol Chem (2005) 1.40
Equivalency of nuclear transfer-derived embryonic stem cells to those derived from fertilized mouse blastocysts. Stem Cells (2006) 1.39
Angiogenesis in the mouse retina: a model system for experimental manipulation. Exp Cell Res (2005) 1.39
Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. J Biol Chem (2002) 1.36
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development. Mech Dev (2006) 1.35
Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population. Exp Hematol (2002) 1.35
Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. Blood (2003) 1.34
Roles of protease-activated receptors in a mouse model of endotoxemia. Blood (2006) 1.32
Uric acid as a danger signal in gout and its comorbidities. Nat Rev Rheumatol (2012) 1.31
Juvenile hormone acid O-methyltransferase in Drosophila melanogaster. Insect Biochem Mol Biol (2008) 1.28
Neuropeptide receptor transcriptome reveals unidentified neuroendocrine pathways. PLoS One (2008) 1.27
Complete sequences of six penicillin-binding protein genes from 40 Streptococcus pneumoniae clinical isolates collected in Japan. Antimicrob Agents Chemother (2004) 1.27
Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells. FASEB J (2003) 1.26
Cytochrome P450 CYP307A1/Spook: a regulator for ecdysone synthesis in insects. Biochem Biophys Res Commun (2005) 1.25
Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells. PLoS One (2012) 1.24
Carotenoid silk coloration is controlled by a carotenoid-binding protein, a product of the Yellow blood gene. Proc Natl Acad Sci U S A (2007) 1.23
Essential role for Galpha13 in endothelial cells during embryonic development. Proc Natl Acad Sci U S A (2005) 1.22
The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol-metabolizing enzyme. J Biol Chem (2011) 1.22
Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo. EMBO J (2006) 1.20
Platelet activation receptor CLEC-2 regulates blood/lymphatic vessel separation by inhibiting proliferation, migration, and tube formation of lymphatic endothelial cells. J Biol Chem (2012) 1.20
Characteristic neuroimaging in patients with tumefactive demyelinating lesions exceeding 30 mm. J Neuroimaging (2011) 1.19
Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development (2009) 1.19
Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice. Eur J Immunol (2003) 1.19
Protective effects of GLP-1 on glomerular endothelium and its inhibition by PKCβ activation in diabetes. Diabetes (2012) 1.18
Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference. Stem Cells (2007) 1.16
Functional characterization of melanocyte stem cells in hair follicles. J Invest Dermatol (2011) 1.09
Identification of a novel prothoracicostatic hormone and its receptor in the silkworm Bombyx mori. J Biol Chem (2005) 1.08
Genetic approach to study the relationship between penicillin-binding protein 3 mutations and Haemophilus influenzae beta-lactam resistance by using site-directed mutagenesis and gene recombinants. Antimicrob Agents Chemother (2005) 1.06
Bombyx prothoracicostatic peptides activate the sex peptide receptor to regulate ecdysteroid biosynthesis. Proc Natl Acad Sci U S A (2010) 1.06
Early ontogenic origin of the hematopoietic stem cell lineage. Proc Natl Acad Sci U S A (2012) 1.06
Blockade of platelet-derived growth factor receptor-beta pathway induces apoptosis of vascular endothelial cells and disrupts glomerular capillary formation in neonatal mice. Am J Pathol (2002) 1.05
Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stage. Blood (2002) 1.05
G protein-coupled receptor for diapause hormone, an inducer of Bombyx embryonic diapause. Biochem Biophys Res Commun (2006) 1.05
FXPRL-amide peptides induce ecdysteroidogenesis through a G-protein coupled receptor expressed in the prothoracic gland of Bombyx mori. Mol Cell Endocrinol (2007) 1.04
Necdin restricts proliferation of hematopoietic stem cells during hematopoietic regeneration. Blood (2009) 1.04
Regulation of insect steroid hormone biosynthesis by innervating peptidergic neurons. Proc Natl Acad Sci U S A (2006) 1.04
Involvement of Runx1 in the down-regulation of fetal liver kinase-1 expression during transition of endothelial cells to hematopoietic cells. Blood (2005) 1.03
ARID3B induces malignant transformation of mouse embryonic fibroblasts and is strongly associated with malignant neuroblastoma. Cancer Res (2006) 1.02
Defective expression of Ras guanyl nucleotide-releasing protein 1 in a subset of patients with systemic lupus erythematosus. J Immunol (2007) 1.02
DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. Circ Res (2010) 1.02
Phospholipase Cdelta1 is required for skin stem cell lineage commitment. EMBO J (2003) 1.02
Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis. Blood (2002) 1.01
PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction. Stem Cells (2012) 1.01
An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori. FEBS J (2009) 0.99
Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development (2011) 0.99
Indispensable role of Bcl2 in the development of the melanocyte stem cell. Dev Biol (2006) 0.98
Mutations in the neverland gene turned Drosophila pachea into an obligate specialist species. Science (2012) 0.97
Endothelialization and altered hematopoiesis by persistent Etv2 expression in mice. Exp Hematol (2012) 0.97
Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-α. J Biol Chem (2012) 0.97
Role of phospholipase C-L2, a novel phospholipase C-like protein that lacks lipase activity, in B-cell receptor signaling. Mol Cell Biol (2003) 0.96
Bombyx orcokinins are brain-gut peptides involved in the neuronal regulation of ecdysteroidogenesis. J Comp Neurol (2011) 0.96
Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation. Stem Cells (2010) 0.95
Putative intermediate precursor between hematogenic endothelial cells and blood cells in the developing embryo. Dev Growth Differ (2003) 0.95
Large scale full-length cDNA sequencing reveals a unique genomic landscape in a lepidopteran model insect, Bombyx mori. G3 (Bethesda) (2013) 0.95
Lnk deletion reinforces the function of bone marrow progenitors in promoting neovascularization and astrogliosis following spinal cord injury. Stem Cells (2010) 0.94
Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3. Blood (2002) 0.94
Simultaneous quantification of individual intermediate steroids in silkworm ecdysone biosynthesis by liquid chromatography-tandem mass spectrometry with multiple reaction monitoring. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.94
Recent studies on insect hormone metabolic pathways mediated by cytochrome P450 enzymes. Biol Pharm Bull (2012) 0.94
Differential regulation of ecdysteroidogenic P450 gene expression in the silkworm, Bombyx mori. Biosci Biotechnol Biochem (2007) 0.94
Different differentiation kinetics of vascular progenitor cells in primate and mouse embryonic stem cells. Circulation (2003) 0.93
Reduced N-acetylaspartate in the basal ganglia of a patient with anti-NMDA receptor encephalitis. Mov Disord (2009) 0.93
BmStart1, a novel carotenoid-binding protein isoform from Bombyx mori, is orthologous to MLN64, a mammalian cholesterol transporter. Biochem Biophys Res Commun (2005) 0.93
Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol (2009) 0.92
Characteristics of patients on hemodialysis therapy for more than 30 years. Ther Apher Dial (2007) 0.92
Multiple mesoderm subsets give rise to endothelial cells, whereas hematopoietic cells are differentiated only from a restricted subset in embryonic stem cell differentiation culture. Stem Cells (2007) 0.91
The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development (2009) 0.90