Published in Nature on April 25, 2002
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Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. Proc Natl Acad Sci U S A (2005) 2.78
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Nuclear envelope defects cause stem cell dysfunction in premature-aging mice. J Cell Biol (2008) 1.36
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The channel kinase, TRPM7, is required for early embryonic development. Proc Natl Acad Sci U S A (2011) 1.29
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In vivo and ex vivo epi-mode pump-probe imaging of melanin and microvasculature. Biomed Opt Express (2011) 1.19
DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune tolerance. Photochem Photobiol (2008) 1.18
Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling. Nat Med (2013) 1.15
Of microenvironments and mammary stem cells. Stem Cell Rev (2007) 1.14
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Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway. Proc Natl Acad Sci U S A (2004) 1.10
Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice. Cancer Res (2007) 1.10
The new stem cell biology: something for everyone. Mol Pathol (2003) 1.10
PAX3 expression in normal skin melanocytes and melanocytic lesions (naevi and melanomas). PLoS One (2010) 1.10
Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice. Mol Cell Biol (2004) 1.09
Stem cell dynamics in the hair follicle niche. Semin Cell Dev Biol (2013) 1.08
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Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos. Development (2010) 1.07
Gene expression profiling gets to the root of human hair follicle stem cells. J Clin Invest (2006) 1.05
Dissecting the bulge in hair regeneration. J Clin Invest (2012) 1.03
TGF-β family signaling in stem cells. Biochim Biophys Acta (2012) 1.01
Aging of the hair follicle pigmentation system. Int J Trichology (2009) 1.00
Melanocyte regeneration reveals mechanisms of adult stem cell regulation. Semin Cell Dev Biol (2008) 0.99
A dual role for SOX10 in the maintenance of the postnatal melanocyte lineage and the differentiation of melanocyte stem cell progenitors. PLoS Genet (2013) 0.99
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Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf. Development (2011) 0.97
Hardwiring Stem Cell Communication through Tissue Structure. Cell (2016) 0.97
Lineage relationship of direct-developing melanocytes and melanocyte stem cells in the zebrafish. PLoS One (2011) 0.96
Extracted hair follicle outer root sheath cell suspension for pigment cell restoration in vitiligo. J Cutan Aesthet Surg (2013) 0.94
Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism. Cancer Res (2010) 0.94
The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles. Differentiation (2008) 0.93
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Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med (2015) 0.92
Stem cells supporting other stem cells. Front Genet (2013) 0.92
Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge. Science (2013) 0.92
Home sweet home: skin stem cell niches. Cell Mol Life Sci (2012) 0.92
Origins of adult pigmentation: diversity in pigment stem cell lineages and implications for pattern evolution. Pigment Cell Melanoma Res (2014) 0.91
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Human hair genealogies and stem cell latency. BMC Biol (2006) 0.89
Isolation of a mesenchymal cell population from murine dermis that contains progenitors of multiple cell lineages. FASEB J (2007) 0.89
Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells. FASEB J (2009) 0.89
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Regenerative Effects of Mesenchymal Stem Cells: Contribution of Muse Cells, a Novel Pluripotent Stem Cell Type that Resides in Mesenchymal Cells. Cells (2012) 0.89
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Melanin: the biophysiology of oral melanocytes and physiological oral pigmentation. Head Face Med (2014) 0.88
Melanoma biology and the promise of zebrafish. Zebrafish (2008) 0.88
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An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development. PLoS Genet (2011) 0.88
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Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts. J Cutan Pathol (2008) 0.87
Somatic deletion of the NF1 gene in a neurofibromatosis type 1-associated malignant melanoma demonstrated by digital PCR. Mol Cancer (2006) 0.87
Melanocytes, melanocyte stem cells, and melanoma stem cells. Clin Dermatol (2013) 0.87
Molecular control of stem cell maintenance in shoot apical meristem. Plant Cell Rep (2005) 0.87
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Human skin cells that express stage-specific embryonic antigen 3 associate with dermal tissue regeneration. Biores Open Access (2012) 0.86
Wound repair and regeneration. Nature (2008) 12.30
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1. Nature (2007) 5.14
Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature (2009) 4.32
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability. Cell (2002) 3.72
Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nat Biotechnol (2005) 3.55
Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell (2007) 3.26
The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut. J Clin Invest (2002) 3.21
Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture. Development (2005) 2.98
Long-term renewal of hair follicles from clonogenic multipotent stem cells. Proc Natl Acad Sci U S A (2005) 2.67
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A (2011) 2.51
Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci U S A (2002) 2.34
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone. Genes Dev (2008) 2.33
Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. Blood (2004) 2.32
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. J Am Acad Dermatol (2009) 2.28
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. J Clin Invest (2002) 2.26
Oligopotent stem cells are distributed throughout the mammalian ocular surface. Nature (2008) 2.24
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. Nat Commun (2011) 2.18
WAVE2 is required for directed cell migration and cardiovascular development. Nature (2003) 2.09
Key roles for transforming growth factor beta in melanocyte stem cell maintenance. Cell Stem Cell (2010) 2.06
Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells. Immunity (2009) 2.05
A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol (2013) 2.04
Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells. Blood (2007) 2.00
Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity. Nat Genet (2004) 1.99
Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells. Nature (2010) 1.94
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice. J Clin Invest (2010) 1.83
Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. Nat Med (2003) 1.78
Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patches. Immunity (2002) 1.74
Cardiac malformations and midline skeletal defects in mice lacking filamin A. Hum Mol Genet (2006) 1.74
Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients. Blood (2007) 1.69
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice. J Cell Biol (2005) 1.69
TGF-beta receptor kinase inhibitor enhances growth and integrity of embryonic stem cell-derived endothelial cells. J Cell Biol (2003) 1.66
Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis. Am J Hum Genet (2011) 1.66
Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm. Blood (2011) 1.61
Bilateral disseminated herpes zoster in an immunocompetent host. Dermatol Online J (2013) 1.60
Somatic mosaicism of CIAS1 in a patient with chronic infantile neurologic, cutaneous, articular syndrome. Arthritis Rheum (2005) 1.59
Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell (2008) 1.58
Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development. J Invest Dermatol (2012) 1.56
Molecular characterization of melanocyte stem cells in their niche. Development (2005) 1.53
Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction. FASEB J (2005) 1.51
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood (2002) 1.51
Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokines. PLoS Biol (2012) 1.51
Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev Cell (2007) 1.49
Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis. J Exp Med (2006) 1.49
Stem cell niches in mammals. Exp Cell Res (2007) 1.49
Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat Cell Biol (2012) 1.48
Notch1 is essential for postnatal hair follicle development and homeostasis. Dev Biol (2005) 1.48
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proc Natl Acad Sci U S A (2003) 1.45
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest (2011) 1.44
The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A (2004) 1.41
Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet (2002) 1.41
Mice transgenic for Kit(V620A): recapitulation of piebaldism but not progressive depigmentation seen in humans with this mutation. J Invest Dermatol (2006) 1.40
Angiogenesis in the mouse retina: a model system for experimental manipulation. Exp Cell Res (2005) 1.39
Equivalency of nuclear transfer-derived embryonic stem cells to those derived from fertilized mouse blastocysts. Stem Cells (2006) 1.39
Organogenesis of peripheral lymphoid organs. Immunol Rev (2003) 1.38
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development. Mech Dev (2006) 1.35
Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population. Exp Hematol (2002) 1.35
Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. Blood (2003) 1.34
Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy. Hum Mol Genet (2005) 1.33
Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis. Arthritis Rheum (2009) 1.33
Control of autoimmune myocarditis and multiorgan inflammation by glucocorticoid-induced TNF receptor family-related protein(high), Foxp3-expressing CD25+ and CD25- regulatory T cells. J Immunol (2006) 1.32
A novel gene essential for the development of single positive thymocytes. Mol Cell Biol (2009) 1.32
Genotype-phenotype correlation of mouse pde6b mutations. Invest Ophthalmol Vis Sci (2005) 1.31
Signatures of diversifying selection in European pig breeds. PLoS Genet (2013) 1.30
Bradykinin is a potent pruritogen in atopic dermatitis: a switch from pain to itch. Pain (2006) 1.29
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Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling. J Allergy Clin Immunol (2012) 1.28
Gefitinib ("Iressa", ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor, reverses breast cancer resistance protein/ABCG2-mediated drug resistance. Cancer Res (2005) 1.28
Chamber-specific differentiation of Nkx2.5-positive cardiac precursor cells from murine embryonic stem cells. FASEB J (2003) 1.26
Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. Eur J Immunol (2010) 1.26
Regulation of pigmentation in zebrafish melanophores. Pigment Cell Res (2006) 1.25
TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci U S A (2002) 1.25
Electrically evoked itch in humans. Pain (2005) 1.25
Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells. PLoS One (2012) 1.24
Compensatory role of Langerhans cells and langerin-positive dermal dendritic cells in the sensitization phase of murine contact hypersensitivity. J Allergy Clin Immunol (2010) 1.21
Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity. PLoS One (2011) 1.21
Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo. EMBO J (2006) 1.20
Upregulation of aquaporin-3 is involved in keratinocyte proliferation and epidermal hyperplasia. J Invest Dermatol (2010) 1.20
Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res (2008) 1.19
Hair follicle stem cells. J Investig Dermatol Symp Proc (2003) 1.19
Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches-deficient mice. Eur J Immunol (2003) 1.19
Protective effects of GLP-1 on glomerular endothelium and its inhibition by PKCβ activation in diabetes. Diabetes (2012) 1.18
BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development (2004) 1.18
Mutation spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and genotype-phenotype correlations in warburg micro syndrome and Martsolf syndrome. Hum Mutat (2013) 1.17
Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J (2003) 1.17
Dissecting the molecular hierarchy for mesendoderm differentiation through a combination of embryonic stem cell culture and RNA interference. Stem Cells (2007) 1.16
Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor. Mamm Genome (2004) 1.16
Presence of visual head tracking differentiates normal sighted from retinal degenerate mice. Neurosci Lett (2002) 1.15
Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake. J Exp Med (2012) 1.15
The multifaceted adult epidermal stem cell. Curr Opin Cell Biol (2003) 1.14
Intravital analysis of vascular permeability in mice using two-photon microscopy. Sci Rep (2013) 1.11