Published in Nat Commun on January 01, 2013
Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents. Nat Med (2016) 1.45
Adult neurogenesis: beyond learning and memory. Annu Rev Psychol (2014) 1.08
Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans. Cell Rep (2015) 0.92
Characterization of the role of adult neurogenesis in touch-screen discrimination learning. Hippocampus (2014) 0.92
Evidence for NG2-glia derived, adult-born functional neurons in the hypothalamus. PLoS One (2013) 0.90
Role of non-neuronal cells in body weight and appetite control. Front Endocrinol (Lausanne) (2015) 0.89
Reactive astrocytes as neural stem or progenitor cells: In vivo lineage, In vitro potential, and Genome-wide expression analysis. Glia (2015) 0.88
Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms. PLoS One (2014) 0.86
Noncanonical Sites of Adult Neurogenesis in the Mammalian Brain. Cold Spring Harb Perspect Biol (2015) 0.85
Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice. Front Neurosci (2014) 0.84
The role of tanycytes in hypothalamic glucosensing. J Cell Mol Med (2015) 0.83
The LIM homeodomain factor Lhx2 is required for hypothalamic tanycyte specification and differentiation. J Neurosci (2014) 0.83
Hypothalamic subependymal niche: a novel site of the adult neurogenesis. Cell Mol Neurobiol (2014) 0.82
Rax-CreERT2 knock-in mice: a tool for selective and conditional gene deletion in progenitor cells and radial glia of the retina and hypothalamus. PLoS One (2014) 0.82
Feed your head: neurodevelopmental control of feeding and metabolism. Annu Rev Physiol (2013) 0.81
Hypothalamic tanycytes-masters and servants of metabolic, neuroendocrine, and neurogenic functions. Front Neurosci (2015) 0.81
Neurodevelopmental origin and adult neurogenesis of the neuroendocrine hypothalamus. Front Cell Neurosci (2015) 0.80
Thyroid hormone and vitamin D regulate VGF expression and promoter activity. J Mol Endocrinol (2015) 0.80
The taxonomy of brain cancer stem cells: what's in a name? Oncoscience (2014) 0.79
Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/β-catenin signaling. Development (2015) 0.79
Opposite effects of a high-fat diet and calorie restriction on ciliary neurotrophic factor signaling in the mouse hypothalamus. Front Neurosci (2013) 0.79
New aspects in fenestrated capillary and tissue dynamics in the sensory circumventricular organs of adult brains. Front Neurosci (2015) 0.78
Glia: silent partners in energy homeostasis and obesity pathogenesis. Diabetologia (2016) 0.77
The contribution of hypothalamic macroglia to the regulation of energy homeostasis. Front Syst Neurosci (2014) 0.77
Dynamic localization of glucokinase and its regulatory protein in hypothalamic tanycytes. PLoS One (2014) 0.77
Fgf10(+) progenitors give rise to the chick hypothalamus by rostral and caudal growth and differentiation. Development (2017) 0.76
Adult neural stem cell behavior underlying constitutive and restorative neurogenesis in zebrafish. Neurogenesis (Austin) (2016) 0.76
Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons. Biol Open (2015) 0.76
Preclinical models for obesity research. Dis Model Mech (2016) 0.75
A sweet taste receptor-dependent mechanism of glucosensing in hypothalamic tanycytes. Glia (2017) 0.75
Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes. Mol Cell Endocrinol (2016) 0.75
Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice. Mol Brain (2016) 0.75
Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting. J Neurosci Methods (2014) 0.75
Quantitative assessment of fibroblast growth factor receptor 1 expression in neurons and glia. PeerJ (2017) 0.75
The Role of Hypothalamic Neuropeptides in Neurogenesis and Neuritogenesis. Neural Plast (2016) 0.75
Tanycytes As Regulators of Seasonal Cycles in Neuroendocrine Function. Front Neurol (2017) 0.75
PPARγ mRNA in the adult mouse hypothalamus: distribution and regulation in response to dietary challenges. Front Neuroanat (2015) 0.75
Environmental Enrichment, Age, and PPARα Interact to Regulate Proliferation in Neurogenic Niches. Front Neurosci (2016) 0.75
Purinergic signalling during development and ageing. Purinergic Signal (2015) 0.75
Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals. Front Endocrinol (Lausanne) (2017) 0.75
Hypothalamic Neurogenesis as an Adaptive Metabolic Mechanism. Front Neurosci (2017) 0.75
Oligodendrocyte development in the embryonic tuberal hypothalamus and the influence of Ascl1. Neural Dev (2016) 0.75
Variable proopiomelanocortin expression in tanycytes of the adult rat hypothalamus and pituitary stalk. J Comp Neurol (2016) 0.75
Distinct Features of Doublecortin as a Marker of Neuronal Migration and Its Implications in Cancer Cell Mobility. Front Mol Neurosci (2017) 0.75
FGF1 - a new weapon to control type 2 diabetes mellitus. Nat Rev Endocrinol (2017) 0.75
-Glial and stem cell expression of murine Fibroblast Growth Factor Receptor 1 in the embryonic and perinatal nervous system. PeerJ (2017) 0.75
Obesity and insulin resistance. J Clin Invest (2000) 10.47
Obesity and the regulation of energy balance. Cell (2001) 9.48
Role of leptin in the neuroendocrine response to fasting. Nature (1996) 8.02
Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature (1994) 7.86
A transgenic model of visceral obesity and the metabolic syndrome. Science (2001) 6.22
Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med (1995) 5.45
Adipogenesis and obesity: rounding out the big picture. Cell (1996) 5.15
The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man. N Engl J Med (1976) 5.09
Leptin. Annu Rev Physiol (2000) 4.78
Distributions of leptin receptor mRNA isoforms in the rat brain. J Comp Neurol (1998) 4.30
Detection of Chlamydia trachomatis antigens in urine as an alternative to swabs and cultures. J Infect Dis (1990) 4.25
Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res (1995) 4.11
Adipose tissue as an endocrine organ. Trends Endocrinol Metab (2000) 4.07
Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol Cell (1998) 3.84
A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature (1996) 3.79
Racial misclassification of Native Americans in a surveillance, epidemiology, and end results cancer registry. J Natl Cancer Inst (1992) 3.62
Insulin resistance--mechanisms, syndromes, and implications. N Engl J Med (1991) 3.58
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest (2000) 3.50
Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science (1987) 3.44
Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature (1998) 3.38
Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron (1999) 3.37
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. J Clin Invest (1995) 3.18
Direct demonstration that receptor crosslinking or aggregation is important in insulin action. Proc Natl Acad Sci U S A (1978) 3.15
Decline in sperm counts: an artefact of changed reference range of "normal"? BMJ (1994) 3.09
Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem (1997) 3.01
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J Comp Neurol (1998) 3.01
Regulation of PPAR gamma gene expression by nutrition and obesity in rodents. J Clin Invest (1996) 2.98
Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance. Science (1975) 2.97
A role for SOX1 in neural determination. Development (1998) 2.85
Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nat Med (1997) 2.73
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest (1997) 2.73
The role of SOCS-3 in leptin signaling and leptin resistance. J Biol Chem (1999) 2.63
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell (1994) 2.58
Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia. J Exp Med (1997) 2.48
SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985. J Biol Chem (2000) 2.41
Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord. Cell (1991) 2.31
Targeted disruption of the beta 3-adrenergic receptor gene. J Biol Chem (1995) 2.27
Obesity and the hypothalamus: novel peptides for new pathways. Cell (1998) 2.25
Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest (1998) 2.23
Asian breast cancer survival in the US: a comparison between Asian immigrants, US-born Asian Americans and Caucasians. Int J Epidemiol (2001) 2.23
Motivational/solution-focused intervention improves HbA1c in adolescents with Type 1 diabetes: a pilot study. Diabet Med (2003) 2.14
Leptin regulation of neuroendocrine systems. Front Neuroendocrinol (2000) 2.12
Selection by two powerful antigens may account for the presence of the major population of human peripheral gamma/delta T cells. J Exp Med (1991) 2.09
Unraveling the central nervous system pathways underlying responses to leptin. Nat Neurosci (1998) 2.08
UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem Biophys Res Commun (1997) 2.06
Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell (1995) 2.05
Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest (2001) 2.05
Severely impaired adipsin expression in genetic and acquired obesity. Science (1987) 2.03
Brown adipose tissue, beta 3-adrenergic receptors, and obesity. Annu Rev Med (1997) 2.03
High definition colonoscopy combined with i-Scan is superior in the detection of colorectal neoplasias compared with standard video colonoscopy: a prospective randomized controlled trial. Endoscopy (2010) 2.01
Chemotropic guidance of developing axons in the mammalian central nervous system. Nature (1989) 2.01
Decreased brown fat markedly enhances susceptibility to diet-induced obesity, diabetes, and hyperlipidemia. Endocrinology (1996) 1.99
Coupled oscillators and biological synchronization. Sci Am (1993) 1.99
Divergent roles of SHP-2 in ERK activation by leptin receptors. J Biol Chem (2000) 1.99
Leptin, nutrition, and reproduction: timing is everything. J Clin Endocrinol Metab (2000) 1.98
Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts. Proc Natl Acad Sci U S A (1986) 1.94
Distribution of glucose transporter messenger RNA transcripts in tissues of rat and man. J Clin Invest (1987) 1.93
Evidence against altered expression of GLUT1 or GLUT4 in skeletal muscle of patients with obesity or NIDDM. Diabetes (1990) 1.93
Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc Natl Acad Sci U S A (1998) 1.92
The structure and differentiation of granulated metrial gland cells of the pregnant mouse uterus. Cell Tissue Res (1977) 1.92
Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats. J Clin Invest (1989) 1.89
Rapid, on-site diagnosis of chlamydial urethritis in men by detection of antigens in urethral swabs and urine. J Clin Microbiol (1991) 1.87
Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology (1999) 1.87
Characterization of the insulin resistance of aging. J Clin Invest (1983) 1.83
In vivo diagnosis of collagenous colitis by confocal endomicroscopy. Gut (2006) 1.82
Distinct physiologic and neuronal responses to decreased leptin and mild hyperleptinemia. Endocrinology (1999) 1.81
Leptin activates neurons in ventrobasal hypothalamus and brainstem. Endocrinology (1997) 1.81
Leptin accelerates the onset of puberty in normal female mice. J Clin Invest (1997) 1.80
Prospective comparison of laparoscopy, ultrasonography and computed tomography in the staging of gastric cancer. Br J Surg (1996) 1.78
Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science (1987) 1.77
Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man. Mol Endocrinol (1989) 1.77
Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress. Endocrinology (1997) 1.75
Characterization of antibodies to the insulin receptor: a cause of insulin-resistant diabetes in man. J Clin Invest (1976) 1.74
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem (1992) 1.74
Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling. J Clin Invest (2001) 1.72
The differentiation of the decidua and the distribution of metrial gland cells in the pregnant mouse uterus. Cell Tissue Res (1978) 1.71
Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin. J Biol Chem (1997) 1.69
Insulin receptors, receptor antibodies, and the mechanism of insulin action. Recent Prog Horm Res (1981) 1.68
Reduced activity of the red-cell sodium-potassium pump in human obesity. N Engl J Med (1980) 1.68
Radio imaging of the very-high-energy gamma-ray emission region in the central engine of a radio galaxy. Science (2009) 1.66
In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology (2000) 1.66
Very-high-energy gamma rays from a distant quasar: how transparent is the universe? Science (2008) 1.65
Leptin prevents fasting-induced suppression of prothyrotropin-releasing hormone messenger ribonucleic acid in neurons of the hypothalamic paraventricular nucleus. Endocrinology (1997) 1.64
The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc Natl Acad Sci U S A (1989) 1.62
Functional properties of leptin receptor isoforms containing the gln-->pro extracellular domain mutation of the fatty rat. Endocrinology (1998) 1.62
Activation of beta(3) adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice. Diabetes (1996) 1.53
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut (2011) 1.51
Symmetry in locomotor central pattern generators and animal gaits. Nature (1999) 1.51
Diagnosis of Chlamydia trachomatis genital infections by cell culture and two enzyme immunoassays detecting different chlamydial antigens. J Clin Microbiol (1989) 1.51
Cooperation of BMP7 and SHH in the induction of forebrain ventral midline cells by prechordal mesoderm. Cell (1997) 1.49
Ethnicity and birthplace in relation to tumor size and stage in Asian American women with breast cancer. Am J Public Health (1999) 1.48
Recognition and characterization of small colonic neoplasia with high-definition colonoscopy using i-Scan is as precise as chromoendoscopy. Dig Liver Dis (2009) 1.46
MedJet--a new CO2-based disposable cleaning device allows safe and effective bowel cleansing during colonoscopy: a pilot study. Endoscopy (2012) 1.44
Specialty differences and the ordering of screening mammography by primary care physicians. J Am Board Fam Pract (1995) 1.43