Published in Angew Chem Int Ed Engl on June 26, 2013
The expanding world of DNA and RNA. Curr Opin Chem Biol (2016) 0.75
Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo. Chemistry (2015) 0.75
Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium. Nucleic Acids Res (2004) 4.19
Synthetic genetic polymers capable of heredity and evolution. Science (2012) 3.59
A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1. Mol Syst Biol (2008) 2.79
A new family of mobilizable suicide plasmids based on broad host range R388 plasmid (IncW) and RP4 plasmid (IncPalpha) conjugative machineries and their cognate Escherichia coli host strains. Res Microbiol (2005) 2.54
Chemical evolution of a bacterium's genome. Angew Chem Int Ed Engl (2011) 2.09
Acinetobacter sp. ADP1: an ideal model organism for genetic analysis and genome engineering. Nucleic Acids Res (2004) 2.04
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity. Nucleic Acids Res (2009) 1.84
Outcome of anatomic ganglionated plexi ablation to treat paroxysmal atrial fibrillation: a 3-year follow-up study. Europace (2010) 1.50
Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects. J Clin Invest (2017) 1.39
A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects. Nucleic Acids Res (2010) 1.26
Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains. Nat Cell Biol (2009) 1.25
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents. J Am Chem Soc (2005) 1.24
Diagnostic accuracy of a new Leishmania PCR for clinical visceral leishmaniasis in Nepal and its role in diagnosis of disease. Trop Med Int Health (2008) 1.21
Phenolic profiling of caffeic acid O-methyltransferase-deficient poplar reveals novel benzodioxane oligolignols. Plant Physiol (2004) 1.19
A simplified and standardized polymerase chain reaction format for the diagnosis of leishmaniasis. J Infect Dis (2008) 1.14
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors. Bioorg Med Chem Lett (2006) 1.13
alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties. J Am Chem Soc (2002) 1.09
Intimate evolution of proteins. Proteome atomic content correlates with genome base composition. J Biol Chem (2003) 1.07
Isolation and purification of a new kalimantacin/batumin-related polyketide antibiotic and elucidation of its biosynthesis gene cluster. Chem Biol (2010) 1.07
Inhibition of MDR1 expression with altritol-modified siRNAs. Nucleic Acids Res (2007) 1.06
Nucleotide analogues containing 2-oxa-bicyclo[2.2.1]heptane and l-alpha-threofuranosyl ring systems: interactions with P2Y receptors. Bioorg Med Chem (2004) 1.04
Recognition of threosyl nucleotides by DNA and RNA polymerases. Nucleic Acids Res (2003) 1.02
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrob Agents Chemother (2010) 1.02
Discovery of 7-N-piperazinylthiazolo[5,4-d]pyrimidine analogues as a novel class of immunosuppressive agents with in vivo biological activity. J Med Chem (2010) 1.02
Correct bond order assignment in a molecular framework using integer linear programming with application to molecules where only non-hydrogen atom coordinates are available. J Chem Inf Model (2005) 1.01
Toward safe genetically modified organisms through the chemical diversification of nucleic acids. Chem Biodivers (2009) 1.00
Molecular analysis of archived blood slides reveals an atypical human Trypanosoma infection. Diagn Microbiol Infect Dis (2008) 0.98
A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics. PLoS One (2013) 0.98
Post-transcriptional modification mapping in the Clostridium acetobutylicum 16S rRNA by mass spectrometry and reverse transcriptase assays. Nucleic Acids Res (2007) 0.98
Base pairing properties of D- and L-cyclohexene nucleic acids (CeNA). Oligonucleotides (2003) 0.97
Complete genome sequence of Streptomyces cattleya NRRL 8057, a producer of antibiotics and fluorometabolites. J Bacteriol (2011) 0.95
Comparative study of the genetic barriers and pathways towards resistance of selective inhibitors of hepatitis C virus replication. Antimicrob Agents Chemother (2011) 0.95
Crystal structure of double helical hexitol nucleic acids. J Am Chem Soc (2002) 0.95
Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization. Nucleic Acids Res (2005) 0.95
The kalimantacin/batumin biosynthesis operon encodes a self-resistance isoform of the FabI bacterial target. Chem Biol (2010) 0.94
The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif. Nucleic Acids Res (2006) 0.94
T. cruzi OligoC-TesT: a simplified and standardized polymerase chain reaction format for diagnosis of Chagas disease. PLoS Negl Trop Dis (2009) 0.94
Structural characterization and biological evaluation of small interfering RNAs containing cyclohexenyl nucleosides. J Am Chem Soc (2007) 0.92
A methyl group controls conformational equilibrium in human mitochondrial tRNA(Lys). J Am Chem Soc (2007) 0.92
Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors. Antimicrob Agents Chemother (2008) 0.92
Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing. Bioorg Med Chem Lett (2011) 0.91
Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis. J Med Chem (2011) 0.91
Synthesis and Antiviral Activity of the alpha-Analogues of 1,5-Anhydrohexitol Nucleosides (1,5-Anhydro-2,3-dideoxy-D-ribohexitol Nucleosides). J Org Chem (1997) 0.90
Gelatin degradation assay reveals MMP-9 inhibitors and function of O-glycosylated domain. World J Biol Chem (2011) 0.90
Pseudouridine detection improvement by derivatization with methyl vinyl sulfone and capillary HPLC-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.89
Increased uptake of antisense oligonucleotides by delivery as double stranded complexes. Biochem Pharmacol (2004) 0.89
Replication of hexitol oligonucleotides as a prelude to the propagation of a third type of nucleic acid in vivo. C R Biol (2003) 0.88
Chemical incorporation of 1-methyladenosine into oligonucleotides. Nucleic Acids Res (2002) 0.88
Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds. Antiviral Res (2013) 0.88
Computational alanine scanning and free energy decomposition for E. coli type I signal peptidase with lipopeptide inhibitor complex. J Mol Graph Model (2007) 0.88
Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine. Nucleosides Nucleotides Nucleic Acids (2003) 0.86
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase. J Virol (2006) 0.86
Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA. J Org Chem (2012) 0.86
Design of bioactive peptides from naturally occurring μ-conotoxin structures. J Biol Chem (2012) 0.85
Structure of the fully modified left-handed cyclohexene nucleic acid sequence GTGTACAC. J Am Chem Soc (2008) 0.85
Biological effects of hexitol and altritol-modified siRNAs targeting B-Raf. Eur J Pharmacol (2009) 0.85
Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides. Nucleic Acids Res (2004) 0.85
Synthesis and properties of aminopropyl nucleic acids. Chembiochem (2005) 0.85
Chemical etiology of nucleic acids: aminopropyl nucleic acids (APNAs). Chem Biodivers (2007) 0.84
Insight into ligand selectivity in HCV NS5B polymerase: molecular dynamics simulations, free energy decomposition and docking. J Mol Model (2009) 0.83
Glycosyl transferase activity of the Escherichia coli penicillin-binding protein 1b: specificity profile for the substrate. Biochemistry (2006) 0.83
Hexitol nucleic acid-containing aptamers are efficient ligands of HIV-1 TAR RNA. Biochemistry (2005) 0.83
N-aminoimidazole derivatives inhibiting retroviral replication via a yet unidentified mode of action. J Med Chem (2003) 0.83
Recognition of HNA and 1,5-anhydrohexitol nucleotides by DNA metabolizing enzymes. Biochim Biophys Acta (2002) 0.83
Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis. Chem Biodivers (2012) 0.83
Paralogous metabolism: S-alkyl-cysteine degradation in Bacillus subtilis. Environ Microbiol (2013) 0.82
Reinforced HNA backbone hydration in the crystal structure of a decameric HNA/RNA hybrid. J Am Chem Soc (2005) 0.82
Influence of the incorporation of a cyclohexenyl nucleic acid (CeNA) residue onto the sequence d(CGCGAATTCGCG). Nucleic Acids Res (2007) 0.82
Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neurons. J Org Chem (2002) 0.82
Synthesis and cleavage experiments of oligonucleotide conjugates with a diimidazole-derived catalytic center. Bioconjug Chem (2002) 0.82
Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside. Nucleic Acids Res (2003) 0.82
Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants. J Med Chem (2008) 0.82
Complete NMR characterization of lychnose from Stellaria media (L.) Vill. Carbohydr Res (2006) 0.82
Structure-function elucidation of a new α-conotoxin, Lo1a, from Conus longurionis. J Biol Chem (2014) 0.81
Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism. J Biol Chem (2002) 0.81
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Bioorg Med Chem Lett (2003) 0.81
Amino acid phosphoramidate nucleotides as alternative substrates for HIV-1 reverse transcriptase. Angew Chem Int Ed Engl (2007) 0.81
Synthesis of D-altritol nucleosides with a 3'-O-tert-butyldimethylsilyl protecting group. Nucleosides Nucleotides Nucleic Acids (2004) 0.81
Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA. Artif DNA PNA XNA (2010) 0.81
Characterization of the posttranscriptional modifications in Legionella pneumophila small-subunit ribosomal RNA. Chem Biodivers (2008) 0.80
Difference in conformational diversity between nucleic acids with a six-membered 'sugar' unit and natural 'furanose' nucleic acids. Nucleic Acids Res (2003) 0.80
Synthesis of novel 5-amino-thiazolo[4,5-d]pyrimidines as E. coli and S. aureus SecA inhibitors. Bioorg Med Chem (2010) 0.80
Comparison of library screening techniques used in the development of dsDNA ligands. Bioorg Med Chem Lett (2003) 0.80
Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue. ChemMedChem (2013) 0.80
Discovery of dual death-associated protein related apoptosis inducing protein kinase 1 and 2 inhibitors by a scaffold hopping approach. J Med Chem (2014) 0.80
Self-complementary sequence context in mature miRNAs. Biochem Biophys Res Commun (2010) 0.80
Nucleoside Phosphate-Conjugates Come of Age: Catalytic Transformation, Polymerase Recognition and Antiviral Properties. Curr Med Chem (2015) 0.80
Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase. J Am Chem Soc (2012) 0.80
Enzymatically catalyzed DNA synthesis using L-Asp-dGMP, L-Asp-dCMP, and L-Asp-dTMP. Chem Biodivers (2008) 0.80
Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods. J Enzyme Inhib Med Chem (2002) 0.80
Evaluation of the type I signal peptidase as antibacterial target for biofilm-associated infections of Staphylococcus epidermidis. Microbiology (2009) 0.79
Structural basis for the role of LYS220 as proton donor for nucleotidyl transfer in HIV-1 reverse transcriptase. Biophys Chem (2011) 0.79