1
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Autophagy
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2012
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20.08
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2
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Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia.
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Cell Metab
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2008
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4.33
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3
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Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes.
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Immunity
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2007
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3.30
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4
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An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice.
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Gut
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2013
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3.07
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5
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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.
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J Cell Biol
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2011
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2.64
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6
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Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine.
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Nat Med
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2012
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2.51
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7
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The emerging role of autophagy in the pathophysiology of diabetes mellitus.
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Autophagy
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2011
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2.18
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8
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Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
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Mol Cell
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2013
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1.95
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9
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STAT1 as a key modulator of cell death.
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Cell Signal
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2006
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1.85
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10
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Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates.
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Proc Natl Acad Sci U S A
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2006
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1.79
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11
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2004
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1.56
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12
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Trophic molecules derived from human mesenchymal stem cells enhance survival, function, and angiogenesis of isolated islets after transplantation.
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2010
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1.44
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13
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2006
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1.39
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14
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J Lipid Res
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2007
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1.37
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15
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Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase.
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J Biol Chem
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2003
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1.35
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16
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TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.
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J Immunol
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2005
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1.33
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17
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Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5.
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2006
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1.31
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18
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Bacterial endotoxin induces the release of high mobility group box 1 via the IFN-beta signaling pathway.
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J Immunol
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2009
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1.21
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19
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NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice.
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Proc Natl Acad Sci U S A
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1.19
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20
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Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice.
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2009
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1.17
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21
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Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes.
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J Clin Invest
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2014
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1.17
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22
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Acute exercise induces FGF21 expression in mice and in healthy humans.
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PLoS One
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2013
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1.17
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23
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Nuclear factor kappaB protects pancreatic beta-cells from tumor necrosis factor-alpha-mediated apoptosis.
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2003
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1.14
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24
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Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha.
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J Immunol
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2004
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1.10
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25
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Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice.
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Diabetes
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2007
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1.10
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26
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Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance.
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J Lipid Res
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2011
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1.08
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27
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Role of autophagy in diabetes and mitochondria.
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28
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Bilateral pheochromocytoma associated with paraganglioma and papillary thyroid carcinoma: report of an unusual case.
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Endocr J
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2007
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1.05
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29
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Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response.
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Endocrinology
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2012
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1.04
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30
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Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha.
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Oncol Rep
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2006
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1.01
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31
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Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation.
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Biochem Biophys Res Commun
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1.01
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32
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Inhibition of autoimmune diabetes by TLR2 tolerance.
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J Immunol
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Regulation by lipocalin-2 of neuronal cell death, migration, and morphology.
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J Neurosci Res
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34
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A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis.
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Diabetes Res Clin Pract
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2010
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0.99
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35
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PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells.
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PLoS One
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2013
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0.98
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36
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Metastasis-associated protein 1 inhibits p53-induced apoptosis.
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0.97
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37
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The associations of total and differential white blood cell counts with obesity, hypertension, dyslipidemia and glucose intolerance in a Korean population.
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J Korean Med Sci
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Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway.
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Mol Cell Biol
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2005
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0.96
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39
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NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia.
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J Biol Chem
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2010
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40
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Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis.
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Cancer Res
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41
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Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling.
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J Immunol
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42
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Regular exercise is associated with a reduction in the risk of NAFLD and decreased liver enzymes in individuals with NAFLD independent of obesity in Korean adults.
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0.94
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43
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Lipid raft proteome reveals that oxidative phosphorylation system is associated with the plasma membrane.
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Expert Rev Proteomics
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44
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Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.
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Mol Cell Endocrinol
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0.93
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Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis.
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J Neuroinflammation
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The favorable outcome of human islet transplantation in Korea: experiences of 10 autologous transplantations.
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Diabetes Metab J
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0.90
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0.90
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52
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Non-HDL-cholesterol/HDL-cholesterol is a better predictor of metabolic syndrome and insulin resistance than apolipoprotein B/apolipoprotein A1.
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0.90
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53
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Korean type 2 diabetes patients have multiple adenomatous polyps compared to non-diabetic controls.
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J Korean Med Sci
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0.89
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Metformin enhances glucagon-like peptide 1 via cooperation between insulin and Wnt signaling.
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55
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0.88
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0.88
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58
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Diabetes Res Clin Pract
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0.88
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59
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Metabolic syndrome as a predictor of cardiovascular diseases and type 2 diabetes in Koreans.
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Int J Cardiol
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Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress.
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Diabetologia
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Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs.
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A patient with primary squamous cell carcinoma of the thyroid intermingled with follicular thyroid carcinoma that remains alive more than 8 years after diagnosis.
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The cutoff value of fasting plasma glucose to differentiate frequencies of cardiovascular risk factors in a Korean population.
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USF inhibits cell proliferation through delay in G2/M phase in FRTL-5 cells.
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Heat shock protein 60 causes osteoclastic bone resorption via toll-like receptor-2 in estrogen deficiency.
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TGF-beta inhibits Fas-mediated apoptosis of a follicular dendritic cell line by down-regulating the expression of Fas and caspase-8: counteracting role of TGF-beta on TNF sensitization of Fas-mediated apoptosis.
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Insulin secretory defect plays a major role in the development of diabetes in patients with distal pancreatectomy.
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RET oligonucleotide microarray for the detection of RET mutations in multiple endocrine neoplasia type 2 syndromes.
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Assessment of β-cell function in human patients.
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Activin A, exendin-4, and glucose stimulate differentiation of human pancreatic ductal cells.
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Mouse mannose-binding lectin-A and ficolin-A inhibit lipopolysaccharide-mediated pro-inflammatory responses on mast cells.
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Improved outcome of islet transplantation in partially pancreatectomized diabetic mice by inhibition of dipeptidyl peptidase-4 with sitagliptin.
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Modulation of glial and neuronal migration by lipocalin-2 in zebrafish.
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Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression.
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Overexpression of USF increases TGF-beta1 protein levels, but G1 phase arrest was not induced in FRTL-5 cells.
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A white blood cell count in the normal concentration range is independently related to cardiorespiratory fitness in apparently healthy Korean men.
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Co-culture with mature islet cells augments the differentiation of insulin-producing cells from pluripotent stem cells.
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