Published in Gut on June 26, 2013
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature (2015) 4.98
Metformin activates a duodenal Ampk-dependent pathway to lower hepatic glucose production in rats. Nat Med (2015) 1.91
Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms. Bioessays (2014) 1.64
Effects of vendor and genetic background on the composition of the fecal microbiota of inbred mice. PLoS One (2015) 1.38
Modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice. ISME J (2014) 1.34
Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. Nat Commun (2015) 1.32
Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling. Cell Metab (2015) 1.22
Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism. Nat Commun (2016) 1.18
Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Sci Rep (2015) 1.18
Microbial shifts in the aging mouse gut. Microbiome (2014) 1.17
Structural modulation of gut microbiota during alleviation of type 2 diabetes with a Chinese herbal formula. ISME J (2014) 1.17
Mucin glycan foraging in the human gut microbiome. Front Genet (2015) 1.14
Circadian disorganization alters intestinal microbiota. PLoS One (2014) 1.12
Metformin ameliorates hepatic steatosis and inflammation without altering adipose phenotype in diet-induced obesity. PLoS One (2014) 1.09
Effect of metformin on metabolic improvement and gut microbiota. Appl Environ Microbiol (2014) 1.08
Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease. World J Gastroenterol (2014) 1.07
Metformin and the gastrointestinal tract. Diabetologia (2016) 1.06
Repurposing metformin: an old drug with new tricks in its binding pockets. Biochem J (2015) 1.03
Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition. Mol Psychiatry (2016) 1.01
The gut microbiome, diet, and links to cardiometabolic and chronic disorders. Nat Rev Nephrol (2015) 0.98
Changes in intestinal barrier function and gut microbiota in high-fat diet-fed rats are dynamic and region dependent. Am J Physiol Gastrointest Liver Physiol (2015) 0.97
The gut microbiota of Colombians differs from that of Americans, Europeans and Asians. BMC Microbiol (2014) 0.95
Adipose tissue-resident regulatory T cells: phenotypic specialization, functions and therapeutic potential. Immunology (2014) 0.95
Microbial determinants of biochemical individuality and their impact on toxicology and pharmacology. Cell Metab (2014) 0.94
A gut feeling to cure diabetes: potential mechanisms of diabetes remission after bariatric surgery. Diabetes Metab J (2014) 0.94
Genome-Wide Association Studies of the Human Gut Microbiota. PLoS One (2015) 0.93
The microbial pharmacists within us: a metagenomic view of xenobiotic metabolism. Nat Rev Microbiol (2016) 0.93
Modulation of gut microbiota by berberine and metformin during the treatment of high-fat diet-induced obesity in rats. Sci Rep (2015) 0.93
Hypothalamic AMPK: a canonical regulator of whole-body energy balance. Nat Rev Endocrinol (2016) 0.92
Current understanding of metformin effect on the control of hyperglycemia in diabetes. J Endocrinol (2016) 0.92
Gut Microbiota and Metabolic Disorders. Diabetes Metab J (2015) 0.91
Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1. Endocrinology (2014) 0.90
Talking microbes: When gut bacteria interact with diet and host organs. Mol Nutr Food Res (2015) 0.88
The Intestinal Microbiota in Metabolic Disease. Nutrients (2016) 0.87
Worms, bacteria, and micronutrients: an elegant model of our diet. Trends Genet (2014) 0.86
Oligofructose protects against arsenic-induced liver injury in a model of environment/obesity interaction. Toxicol Appl Pharmacol (2015) 0.86
Altered microbiota in microscopic colitis. Gut (2015) 0.86
Probiotics and immunity: provisional role for personalized diets and disease prevention. EPMA J (2015) 0.84
Anti-obesity Effect of Capsaicin in Mice Fed with High-Fat Diet Is Associated with an Increase in Population of the Gut Bacterium Akkermansia muciniphila. Front Microbiol (2017) 0.84
Bifidobacterium pseudocatenulatum CECT 7765 Reduces Obesity-Associated Inflammation by Restoring the Lymphocyte-Macrophage Balance and Gut Microbiota Structure in High-Fat Diet-Fed Mice. PLoS One (2015) 0.84
Specific gut microbiota features and metabolic markers in postmenopausal women with obesity. Nutr Diabetes (2015) 0.83
Probiotic-based strategies for therapeutic and prophylactic use against multiple gastrointestinal diseases. Front Microbiol (2015) 0.82
Mucosal Interactions between Genetics, Diet, and Microbiome in Inflammatory Bowel Disease. Front Immunol (2016) 0.82
Fermented Rhizoma Atractylodis Macrocephalae alleviates high fat diet-induced obesity in association with regulation of intestinal permeability and microbiota in rats. Sci Rep (2015) 0.82
Flos Lonicera ameliorates obesity and associated endotoxemia in rats through modulation of gut permeability and intestinal microbiota. PLoS One (2014) 0.82
Can We Prevent Obesity-Related Metabolic Diseases by Dietary Modulation of the Gut Microbiota? Adv Nutr (2016) 0.82
Gut microbiome in health and disease: Linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases. Pharmacol Ther (2015) 0.82
Distinctly altered gut microbiota in the progression of liver disease. Oncotarget (2016) 0.82
Obesity, Asthma, and the Microbiome. Physiology (Bethesda) (2016) 0.81
New mechanisms of metformin action: Focusing on mitochondria and the gut. J Diabetes Investig (2015) 0.80
Adaptation of Akkermansia muciniphila to the oxic-anoxic interface of the mucus layer. Appl Environ Microbiol (2016) 0.80
Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome. Sci Rep (2016) 0.80
Innate immune signaling and gut-liver interactions in non-alcoholic fatty liver disease. Hepatobiliary Surg Nutr (2014) 0.80
Molecular analysis of the microbiota in hard feces from healthy rabbits (Oryctolagus cuniculus) medicated with long term oral meloxicam. BMC Vet Res (2014) 0.80
Impact of pelvic radiotherapy on gut microbiota of gynecological cancer patients revealed by massive pyrosequencing. PLoS One (2013) 0.79
Inclusion of Konjac Flour in the Gestation Diet Changes the Gut Microbiota, Alleviates Oxidative Stress, and Improves Insulin Sensitivity in Sows. Appl Environ Microbiol (2016) 0.79
The antidiabetic gutsy role of metformin uncovered? Gut (2013) 0.79
Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice. Diabetol Metab Syndr (2015) 0.79
Characterization of Outer Membrane Proteome of Akkermansia muciniphila Reveals Sets of Novel Proteins Exposed to the Human Intestine. Front Microbiol (2016) 0.79
Diabetes Mellitus and Increased Tuberculosis Susceptibility: The Role of Short-Chain Fatty Acids. J Diabetes Res (2015) 0.79
Update on the treatment of type 2 diabetes mellitus. World J Diabetes (2016) 0.79
Gut microbiota impact on stroke outcome: Fad or fact? J Cereb Blood Flow Metab (2016) 0.79
Triggering Akkermansia with dietary polyphenols: A new weapon to combat the metabolic syndrome? Gut Microbes (2016) 0.79
Molecular Pathogenesis of NASH. Int J Mol Sci (2016) 0.78
The Metabolic Role of Gut Microbiota in the Development of Nonalcoholic Fatty Liver Disease and Cardiovascular Disease. Int J Mol Sci (2016) 0.78
Once-daily delayed-release metformin lowers plasma glucose and enhances fasting and postprandial GLP-1 and PYY: results from two randomised trials. Diabetologia (2016) 0.78
Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs. Am J Physiol Gastrointest Liver Physiol (2014) 0.78
Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium. Sci Rep (2016) 0.78
Listening to Our Gut: Contribution of Gut Microbiota and Cardiovascular Risk in Diabetes Pathogenesis. Curr Diab Rep (2015) 0.78
Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function. PLoS One (2017) 0.77
Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice. Sci Rep (2016) 0.77
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis. Autophagy (2016) 0.77
Conjugated Linoleic Acid Supplementation under a High-Fat Diet Modulates Stomach Protein Expression and Intestinal Microbiota in Adult Mice. PLoS One (2015) 0.77
Obesity-associated cancer risk: the role of intestinal microbiota in the etiology of the host proinflammatory state. Transl Res (2016) 0.77
Probiotic mixture improves fatty liver disease by virtue of its action on lipid profiles, leptin, and inflammatory biomarkers. BMC Complement Altern Med (2017) 0.77
Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling. Acta Pharmacol Sin (2016) 0.77
Faecal microbiota characterisation of horses using 16 rdna barcoded pyrosequencing, and carriage rate of clostridium difficile at hospital admission. BMC Microbiol (2015) 0.77
Role of innate immunity in the pathogenesis of type 1 and type 2 diabetes. J Korean Med Sci (2014) 0.77
Factors Influencing the Gut Microbiota, Inflammation, and Type 2 Diabetes. J Nutr (2017) 0.77
Chemical transformation of xenobiotics by the human gut microbiota. Science (2017) 0.76
Alterations in Gut Microbiota and Immunity by Dietary Fat. Yonsei Med J (2017) 0.76
Different subtype strains of Akkermansia muciniphila abundantly colonize in southern China. J Appl Microbiol (2016) 0.76
Berberine Attenuates Intestinal Mucosal Barrier Dysfunction in Type 2 Diabetic Rats. Front Pharmacol (2017) 0.76
Effect of Roux-en-Y gastric bypass surgery on intestinal Akkermansia muciniphila. World J Gastrointest Surg (2016) 0.76
Activation of bile acid signaling improves metabolic phenotypes in high-fat diet-induced obese mice. Am J Physiol Gastrointest Liver Physiol (2016) 0.76
The gut microbiota: a key regulator of metabolic diseases. BMB Rep (2016) 0.76
Fatty acids from diet and microbiota regulate energy metabolism. F1000Res (2015) 0.76
Predicting Clostridium difficile infection in diabetic patients and the effect of metformin therapy: a retrospective, case-control study. Eur J Clin Microbiol Infect Dis (2015) 0.76
Relationship between the microbiota in different sections of the gastrointestinal tract, and the body weight of broiler chickens. Springerplus (2016) 0.76
The stress polarity pathway: AMPK 'GIV'-es protection against metabolic insults. Aging (Albany NY) (2017) 0.76
Fecal microbiota transplantation in metabolic syndrome: History, present and future. Gut Microbes (2017) 0.75
Longitudinal survey of Clostridium difficile presence and gut microbiota composition in a Belgian nursing home. BMC Microbiol (2016) 0.75
In Vivo Effects of Pichia Pastoris-Expressed Antimicrobial Peptide Hepcidin on the Community Composition and Metabolism Gut Microbiota of Rats. PLoS One (2016) 0.75
Causality of small and large intestinal microbiota in weight regulation and insulin resistance. Mol Metab (2016) 0.75
Neuropeptide Y Overexpressing Female and Male Mice Show Divergent Metabolic but Not Gut Microbial Responses to Prenatal Metformin Exposure. PLoS One (2016) 0.75
Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice. Aging Dis (2017) 0.75
Targeting gut microbiota: a potential promising therapy for diabetic kidney disease. Am J Transl Res (2016) 0.75
Microflora Disturbance during Progression of Glucose Intolerance and Effect of Sitagliptin: An Animal Study. J Diabetes Res (2016) 0.75
Helicobacter pylori Infection Aggravates Diet-induced Insulin Resistance in Association With Gut Microbiota of Mice. EBioMedicine (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila. Science (2008) 5.14
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. Cell Metab (2008) 4.33
Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes. Immunity (2007) 3.30
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst (2003) 2.91
Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol (2011) 2.64
Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine. Nat Med (2012) 2.51
The emerging role of autophagy in the pathophysiology of diabetes mellitus. Autophagy (2011) 2.18
Metagenomic analysis of kimchi, a traditional Korean fermented food. Appl Environ Microbiol (2011) 2.08
Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol Cell (2013) 1.95
STAT1 as a key modulator of cell death. Cell Signal (2006) 1.85
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates. Proc Natl Acad Sci U S A (2006) 1.79
Investigation of archaeal and bacterial diversity in fermented seafood using barcoded pyrosequencing. ISME J (2009) 1.69
Amplification methods bias metagenomic libraries of uncultured single-stranded and double-stranded DNA viruses. Appl Environ Microbiol (2011) 1.62
Prevalence, clinical and ultrasonographic characteristics of thyroid incidentalomas. Thyroid (2004) 1.56
Metatranscriptome analysis of lactic acid bacteria during kimchi fermentation with genome-probing microarrays. Int J Food Microbiol (2009) 1.54
Amplification of uncultured single-stranded DNA viruses from rice paddy soil. Appl Environ Microbiol (2008) 1.53
Comparing microarrays and next-generation sequencing technologies for microbial ecology research. Trends Biotechnol (2010) 1.52
Comparative analysis of Korean human gut microbiota by barcoded pyrosequencing. PLoS One (2011) 1.49
Trophic molecules derived from human mesenchymal stem cells enhance survival, function, and angiogenesis of isolated islets after transplantation. Transplantation (2010) 1.44
Henoch-Schönlein purpura associated with propylthiouracil overdose. Nephrol Dial Transplant (2006) 1.39
Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes. J Lipid Res (2007) 1.37
Resistance of mitochondrial DNA-depleted cells against cell death: role of mitochondrial superoxide dismutase. J Biol Chem (2003) 1.35
TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker. J Immunol (2005) 1.33
Novel transcriptional regulation of the schlafen-2 gene in macrophages in response to TLR-triggered stimulation. Mol Immunol (2007) 1.32
Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5. Nat Cell Biol (2006) 1.31
Diversity and abundance of single-stranded DNA viruses in human feces. Appl Environ Microbiol (2011) 1.27
Phylogenetic characterization of two novel commensal bacteria involved with innate immune homeostasis in Drosophila melanogaster. Appl Environ Microbiol (2008) 1.22
Diversity of ammonium-oxidizing bacteria in a granular sludge anaerobic ammonium-oxidizing (anammox) reactor. Environ Microbiol (2008) 1.22
Bacterial endotoxin induces the release of high mobility group box 1 via the IFN-beta signaling pathway. J Immunol (2009) 1.21
Preparation and characterization of simvastatin/hydroxypropyl-beta-cyclodextrin inclusion complex using supercritical antisolvent (SAS) process. Eur J Pharm Biopharm (2006) 1.19
NF-kappa B prevents beta cell death and autoimmune diabetes in NOD mice. Proc Natl Acad Sci U S A (2007) 1.19
Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice. Diabetes (2009) 1.17
Alishewanella agri sp. nov., isolated from landfill soil. Int J Syst Evol Microbiol (2009) 1.17
Amyloidogenic peptide oligomer accumulation in autophagy-deficient β cells induces diabetes. J Clin Invest (2014) 1.17
Acute exercise induces FGF21 expression in mice and in healthy humans. PLoS One (2013) 1.17
Physicochemical properties and oral bioavailability of amorphous atorvastatin hemi-calcium using spray-drying and SAS process. Int J Pharm (2008) 1.16
Metagenomic characterization of airborne viral DNA diversity in the near-surface atmosphere. J Virol (2012) 1.15
Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process. Int J Pharm (2005) 1.15
Nuclear factor kappaB protects pancreatic beta-cells from tumor necrosis factor-alpha-mediated apoptosis. Diabetes (2003) 1.14
Alishewanella aestuarii sp. nov., isolated from tidal flat sediment, and emended description of the genus Alishewanella. Int J Syst Evol Microbiol (2009) 1.12
Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha. J Immunol (2004) 1.10
Alishewanella jeotgali sp. nov., isolated from traditional fermented food, and emended description of the genus Alishewanella. Int J Syst Evol Microbiol (2009) 1.10
Essential role for signal transducer and activator of transcription-1 in pancreatic beta-cell death and autoimmune type 1 diabetes of nonobese diabetic mice. Diabetes (2007) 1.10
Bacterial, archaeal, and eukaryal diversity in the intestines of Korean people. J Microbiol (2008) 1.09
Influence of soil components on the biodegradation of benzene, toluene, ethylbenzene, and o-, m-, and p-xylenes by the newly isolated bacterium Pseudoxanthomonas spadix BD-a59. Appl Environ Microbiol (2008) 1.09
Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance. J Lipid Res (2011) 1.08
Association of CD47 with natural killer cell-mediated cytotoxicity of head-and-neck squamous cell carcinoma lines. Tumour Biol (2008) 1.08
Role of autophagy in diabetes and mitochondria. Ann N Y Acad Sci (2010) 1.06
Bilateral pheochromocytoma associated with paraganglioma and papillary thyroid carcinoma: report of an unusual case. Endocr J (2007) 1.05
Role of hypothalamic proopiomelanocortin neuron autophagy in the control of appetite and leptin response. Endocrinology (2012) 1.04
Bacterial community analysis during fermentation of ten representative kinds of kimchi with barcoded pyrosequencing. Food Microbiol (2011) 1.03
Kocuria atrinae sp. nov., isolated from traditional Korean fermented seafood. Int J Syst Evol Microbiol (2009) 1.02
Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha. Oncol Rep (2006) 1.01
Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation. Biochem Biophys Res Commun (2013) 1.01
Numerical and functional deficiencies of natural killer T cells in systemic lupus erythematosus: their deficiency related to disease activity. Rheumatology (Oxford) (2011) 1.01
Inhibition of autoimmune diabetes by TLR2 tolerance. J Immunol (2011) 1.01
Leucobacter celer sp. nov., isolated from Korean fermented seafood. Int J Syst Evol Microbiol (2010) 1.01
Regulation by lipocalin-2 of neuronal cell death, migration, and morphology. J Neurosci Res (2011) 1.00
A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis. Diabetes Res Clin Pract (2010) 0.99
Metagenomic analysis of the viral communities in fermented foods. Appl Environ Microbiol (2010) 0.99
PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells. PLoS One (2013) 0.98
The associations of total and differential white blood cell counts with obesity, hypertension, dyslipidemia and glucose intolerance in a Korean population. J Korean Med Sci (2008) 0.97
Metastasis-associated protein 1 inhibits p53-induced apoptosis. Oncol Rep (2007) 0.97
Strict vegetarian diet improves the risk factors associated with metabolic diseases by modulating gut microbiota and reducing intestinal inflammation. Environ Microbiol Rep (2013) 0.97
NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia. J Biol Chem (2010) 0.96
Essential role of STAT1 in caspase-independent cell death of activated macrophages through the p38 mitogen-activated protein kinase/STAT1/reactive oxygen species pathway. Mol Cell Biol (2005) 0.96
Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis. Cancer Res (2005) 0.96
Thyrotropin-mediated repression of class II trans-activator expression in thyroid cells: involvement of STAT3 and suppressor of cytokine signaling. J Immunol (2003) 0.95
Kocuria salsicia sp. nov., isolated from salt-fermented seafood. Int J Syst Evol Microbiol (2010) 0.95
Regular exercise is associated with a reduction in the risk of NAFLD and decreased liver enzymes in individuals with NAFLD independent of obesity in Korean adults. PLoS One (2012) 0.94
Lipid raft proteome reveals that oxidative phosphorylation system is associated with the plasma membrane. Expert Rev Proteomics (2010) 0.94
Improved supersaturation and oral absorption of dutasteride by amorphous solid dispersions. Chem Pharm Bull (Tokyo) (2012) 0.93
Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction. Mol Cell Endocrinol (2012) 0.93
Resistance of mitochondrial DNA-deficient cells to TRAIL: role of Bax in TRAIL-induced apoptosis. Oncogene (2002) 0.93
Kocuria koreensis sp. nov., isolated from fermented seafood. Int J Syst Evol Microbiol (2009) 0.93
Development of microbial genome-probing microarrays using digital multiple displacement amplification of uncultivated microbial single cells. Environ Sci Technol (2008) 0.93
Bioavailability of indomethacin-saccharin cocrystals. J Pharm Pharmacol (2010) 0.92
Blautia stercoris sp. nov., isolated from human faeces. Int J Syst Evol Microbiol (2011) 0.92
Sulfitobacter litoralis sp. nov., a marine bacterium isolated from the East Sea, Korea. Int J Syst Evol Microbiol (2007) 0.92
Pseudoalteromonas marina sp. nov., a marine bacterium isolated from tidal flats of the Yellow Sea, and reclassification of Pseudoalteromonas sagamiensis as Algicola sagamiensis comb. nov. Int J Syst Evol Microbiol (2007) 0.91
Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity. J Neuroinflammation (2012) 0.91
Photoinactivation of photosystem II in leaves. Photosynth Res (2005) 0.91
Blautia faecis sp. nov., isolated from human faeces. Int J Syst Evol Microbiol (2012) 0.91
Brachybacterium squillarum sp. nov., isolated from salt-fermented seafood. Int J Syst Evol Microbiol (2010) 0.91