PubRank

Brian J Nickoloff

Author PubWeight™ 94.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness. Nat Med 2006 4.54
2 Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med 2004 3.96
3 Skin immune sentinels in health and disease. Nat Rev Immunol 2009 3.52
4 The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J Biol Chem 2007 3.24
5 Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-alpha. J Exp Med 2004 2.63
6 The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation. Cancer Cell 2005 2.34
7 Uncovering histologic criteria with prognostic significance in toxic epidermal necrolysis. Arch Dermatol 2005 2.28
8 Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Res 2005 2.27
9 Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J Clin Invest 2007 2.22
10 Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res 2008 2.19
11 Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest 2008 1.89
12 Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis. J Immunol 2011 1.79
13 Clonal persistence and evolution during a decade of recurrent melanoma. J Invest Dermatol 2006 1.69
14 Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene 2005 1.63
15 Cutting edge: A critical functional role for IL-23 in psoriasis. J Immunol 2010 1.61
16 A phase I trial of tumor lysate-pulsed dendritic cells in the treatment of advanced cancer. Clin Cancer Res 2002 1.56
17 Cracking the cytokine code in psoriasis. Nat Med 2007 1.47
18 Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA. Cancer Res 2006 1.41
19 Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation. Cancer Res 2008 1.41
20 p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol Cancer Ther 2004 1.40
21 Transendothelial function of human metastatic melanoma cells: role of the microenvironment in cell-fate determination. Cancer Res 2002 1.36
22 Active Notch1 confers a transformed phenotype to primary human melanocytes. Cancer Res 2009 1.36
23 The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. J Immunol 2002 1.30
24 Inhibition of PAX3 by TGF-beta modulates melanocyte viability. Mol Cell 2008 1.26
25 Notch-independent regulation of Hes-1 expression by c-Jun N-terminal kinase signaling in human endothelial cells. Lab Invest 2006 1.24
26 Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence. Oncogene 2003 1.23
27 Conservation of genetic alterations in recurrent melanoma supports the melanoma stem cell hypothesis. Cancer Res 2008 1.22
28 Focal adhesion kinase promotes the aggressive melanoma phenotype. Cancer Res 2005 1.22
29 Notch signaling regulates mouse and human Th17 differentiation. J Immunol 2011 1.21
30 A 'hairy' privilege. Trends Immunol 2005 1.21
31 4-Tertiary butyl phenol exposure sensitizes human melanocytes to dendritic cell-mediated killing: relevance to vitiligo. J Invest Dermatol 2005 1.20
32 Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack. J Invest Dermatol 2007 1.18
33 Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples. Nucleic Acids Res 2009 1.17
34 Notch-1 regulates cell death independently of differentiation in murine erythroleukemia cells through multiple apoptosis and cell cycle pathways. J Cell Physiol 2004 1.13
35 Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue. J Transl Med 2012 1.07
36 Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Res 2005 1.06
37 Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene 2002 1.05
38 Autoimmune aspects of depigmentation in vitiligo. J Investig Dermatol Symp Proc 2004 1.01
39 Innate immune-related receptors in normal and psoriatic skin. Arch Pathol Lab Med 2003 1.00
40 Treatment strategies in toxic epidermal necrolysis syndrome: where are we at? J Burn Care Res 2008 1.00
41 Immunology of the human nail apparatus: the nail matrix is a site of relative immune privilege. J Invest Dermatol 2005 0.99
42 A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. Cancer Prev Res (Phila) 2010 0.99
43 Characterization of tissue specific expression of Notch-1 in human tissues. Biol Cell 2004 0.98
44 The helix-loop-helix protein id-1 delays onset of replicative senescence in human endothelial cells. Lab Invest 2002 0.97
45 Cross-validation of murine UV signal transduction pathways in human skin. Photochem Photobiol 2008 0.97
46 Deepening our understanding of immune sentinels in the skin. J Clin Invest 2007 0.96
47 Digital epiluminescence microscopy monitoring of high-risk patients. Arch Dermatol 2004 0.94
48 Knockdown of p53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 2005 0.93
49 Interferon-gamma reduces melanosomal antigen expression and recognition of melanoma cells by cytotoxic T cells. Am J Pathol 2002 0.91
50 A role for tumor necrosis factor-alpha-mediated endothelial apoptosis in the development of experimental idiopathic pneumonia syndrome. Transplantation 2004 0.88
51 What have we learned in dermatology from the biologic therapies? J Am Acad Dermatol 2006 0.87
52 Loss of inositol polyphosphate 5-phosphatase is an early event in development of cutaneous squamous cell carcinoma. Cancer Prev Res (Phila) 2010 0.86
53 Role of INK4a/Arf locus-encoded senescent checkpoints activated in normal and psoriatic keratinocytes. Am J Pathol 2003 0.86
54 Reactivity of resident immunocytes in normal and prepsoriatic skin using an ex vivo skin-explant model system. Arch Pathol Lab Med 2003 0.86
55 Low-dose UV-radiation sensitizes keratinocytes to TRAIL-induced apoptosis. J Cell Physiol 2004 0.85
56 Estimation of size of clonal unit for keratinocytes in normal human skin. Arch Pathol Lab Med 2002 0.84
57 Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma. Mol Cancer Ther 2013 0.83
58 Occurrence of a basal cell carcinoma and dermatofibroma in a smallpox vaccination scar. Dermatol Surg 2007 0.82
59 Specifically targeting ERK1 or ERK2 kills melanoma cells. J Transl Med 2012 0.82
60 Defining the transcriptome of accelerated and replicatively senescent keratinocytes reveals links to differentiation, interferon signaling, and Notch related pathways. J Cell Biochem 2006 0.81
61 Melanoma genotypes and phenotypes get personal. Lab Invest 2013 0.81
62 Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations. Exp Dermatol 2002 0.80
63 Proliferating cultured human keratinocytes are more susceptible to apoptosis compared with mouse keratinocytes. J Invest Dermatol 2004 0.80
64 Defining the caspase-containing apoptotic machinery contributing to cornification in human epidermal equivalents. Exp Dermatol 2006 0.79
65 Expression of gp100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region. Pigment Cell Res 2004 0.79
66 Knock down of p53 levels in human keratinocytes increases susceptibility to type I and type II interferon-induced apoptosis mediated by a TRAIL dependent pathway. J Dermatol Sci 2005 0.79
67 Targeting TNFalpha rapidly reduces density of dendritic cells and macrophages in psoriatic plaques with restoration of epidermal keratinocyte differentiation. J Dermatol Sci 2007 0.78
68 Human herpesvirus 8 reactivation and human immunodeficiency virus type 1 gp120. Arch Pathol Lab Med 2002 0.78
69 Alefacept in corticosteroid refractory graft versus host disease: early results indicate promising activity. J Dermatolog Treat 2007 0.78
70 The skin cancer paradox of psoriasis: a matter of life and death decisions in the epidermis. Arch Dermatol 2004 0.77
71 Role for Id-1 in immunobiology of normal keratinocytes and in basal cell carcinoma. Exp Dermatol 2003 0.76
72 Saving the skin from drug-induced detachment. Nat Med 2008 0.75
73 56th annual Montagna Symposium on the Biology of Skin: Epidermal T-cell interactions--clinicopathological and basic mechanisms. J Invest Dermatol 2008 0.75
74 Ecthyma gangrenosum following toxic epidermal necrolysis syndrome in a 3-year-old boy-a survivable series of events. J Burn Care Res 2008 0.75
75 Sweet's syndrome with neurologic manifestations in a patient with esophageal adenocarcinoma: case report and review of the literature. Int J Dermatol 2009 0.75
76 Senescent human keratinocytes suppress colony formation of HeLa cells. J Dermatol Sci 2005 0.75