Published in J Antimicrob Chemother on July 05, 2013
The genetic basis of the fitness costs of antimicrobial resistance: a meta-analysis approach. Evol Appl (2014) 0.95
Persistence of a pKPN3-like CTX-M-15-encoding IncFIIK plasmid in a Klebsiella pneumonia ST17 host during two years of intestinal colonization. PLoS One (2015) 0.78
Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium. Antimicrob Agents Chemother (2016) 0.78
Gastrointestinal Tract Colonization Dynamics by Different Enterococcus faecium Clades. J Infect Dis (2015) 0.78
A model-guided analysis and perspective on the evolution and epidemiology of antibiotic resistance and its future. Curr Opin Microbiol (2014) 0.78
The evolutionary dynamics of integrons in changing environments. ISME J (2016) 0.77
Epistasis and the Evolution of Antimicrobial Resistance. Front Microbiol (2017) 0.76
Evolution and Diversity of the Antimicrobial Resistance Associated Mobilome in Streptococcus suis: A Probable Mobile Genetic Elements Reservoir for Other Streptococci. Front Cell Infect Microbiol (2016) 0.75
Decreased Fitness and Virulence in ST10 Escherichia coli Harboring blaNDM-5 and mcr-1 against a ST4981 Strain with blaNDM-5. Front Cell Infect Microbiol (2017) 0.75
A Silenced vanA Gene Cluster on a Transferable Plasmid Caused an Outbreak of Vancomycin-Variable Enterococci. Antimicrob Agents Chemother (2016) 0.75
Vancomycin-resistant enterococci. Lancet (1988) 11.27
Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J Bacteriol (1993) 6.96
Test of synergistic interactions among deleterious mutations in bacteria. Nature (1997) 6.40
Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbiol (2010) 6.18
The biological cost of antibiotic resistance. Curr Opin Microbiol (1999) 6.08
Evolution of a bacteria/plasmid association. Nature (1988) 6.00
The competitive cost of antibiotic resistance in Mycobacterium tuberculosis. Science (2006) 5.41
Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria. Genetics (2000) 4.98
Vancomycin resistance in gram-positive cocci. Clin Infect Dis (2006) 4.95
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance. Science (2000) 4.48
Reducing antibiotic resistance. Nature (1996) 3.57
The population genetics of antibiotic resistance. Clin Infect Dis (1997) 3.51
Mutation frequency and biological cost of antibiotic resistance in Helicobacter pylori. Proc Natl Acad Sci U S A (2001) 3.42
Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg Infect Dis (2005) 3.32
Amelioration of the cost of conjugative plasmid carriage in Eschericha coli K12. Genetics (2003) 2.39
Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium. Mol Microbiol (2002) 2.32
Predicting antibiotic resistance. Nat Rev Microbiol (2007) 2.28
Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. Antimicrob Agents Chemother (2007) 2.01
Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (2006) 1.98
Restricted gene flow among hospital subpopulations of Enterococcus faecium. MBio (2012) 1.92
The evolution of a conjugative plasmid and its ability to increase bacterial fitness. Biol Lett (2005) 1.67
Population biology of Gram-positive pathogens: high-risk clones for dissemination of antibiotic resistance. FEMS Microbiol Rev (2011) 1.66
Stability of a promiscuous plasmid in different hosts: no guarantee for a long-term relationship. Microbiology (2007) 1.63
Mobile genetic elements and their contribution to the emergence of antimicrobial resistant Enterococcus faecalis and Enterococcus faecium. Clin Microbiol Infect (2010) 1.63
Enhancement of host fitness by the sul2-coding plasmid p9123 in the absence of selective pressure. J Antimicrob Chemother (2004) 1.58
Tn916-like genetic elements: a diverse group of modular mobile elements conferring antibiotic resistance. FEMS Microbiol Rev (2011) 1.45
Inducible expression eliminates the fitness cost of vancomycin resistance in enterococci. Proc Natl Acad Sci U S A (2010) 1.44
Stability, persistence, and evolution of plasmid-encoded VanA glycopeptide resistance in enterococci in the absence of antibiotic selection in vitro and in gnotobiotic mice. Microb Drug Resist (2002) 1.27
Frequent conjugative transfer accelerates adaptation of a broad-host-range plasmid to an unfavorable Pseudomonas putida host. FEMS Microbiol Ecol (2006) 1.25
Typeability of Tn1546-like elements in vancomycin-resistant enterococci using long-range PCRs and specific analysis of polymorphic regions. Microb Drug Resist (2000) 1.14
Glycopeptide-resistant enterococci: deciphering virulence, resistance and epidemicity. Curr Opin Infect Dis (2007) 1.12
Development of an integrative vector for the expression of antisense RNA in Clostridium difficile. J Microbiol Methods (2003) 1.08
Fitness of Escherichia coli strains carrying expressed and partially silent IncN and IncP1 plasmids. BMC Microbiol (2012) 1.07
Factors affecting the reversal of antimicrobial-drug resistance. Lancet Infect Dis (2009) 1.06
Dosage of Tn916 circular intermediates in Enterococcus faecalis. Plasmid (1995) 1.06
Retrospective evidence for a biological cost of vancomycin resistance determinants in the absence of glycopeptide selective pressures. J Antimicrob Chemother (2011) 1.04
Host range of enterococcal vanA plasmids among Gram-positive intestinal bacteria. J Antimicrob Chemother (2010) 1.03
Virulence and antimicrobial resistance in clinical Enterococcus faecium. Int J Antimicrob Agents (2008) 1.00
Antibiotic resistant enterococci-tales of a drug resistance gene trafficker. Int J Med Microbiol (2013) 1.00
Sexual isolation in Acinetobacter baylyi is locus-specific and varies 10,000-fold over the genome. Genetics (2009) 0.99
Transfer of plasmid and chromosomal glycopeptide resistance determinants occurs more readily in the digestive tract of mice than in vitro and exconjugants can persist stably in vivo in the absence of glycopeptide selection. J Antimicrob Chemother (2007) 0.94
Characterization of the ends and target site of a novel tetracycline resistance-encoding conjugative transposon from Enterococcus faecium 664.1H1. J Bacteriol (2006) 0.93
The in vitro fitness cost of antimicrobial resistance in Escherichia coli varies with the growth conditions. FEMS Microbiol Lett (2009) 0.89
A trade-off between the fitness cost of functional integrases and long-term stability of integrons. PLoS Pathog (2012) 0.89
Demonstration of conjugative transposon (Tn5397)-mediated horizontal gene transfer between Clostridium difficile and Enterococcus faecalis. Antimicrob Agents Chemother (2010) 0.88
Intra- and interspecies genomic transfer of the Enterococcus faecalis pathogenicity island. PLoS One (2011) 0.87
Different genetic supports for the tet(S) gene in Enterococci. Antimicrob Agents Chemother (2012) 0.85
Characterization of the conjugative transposon Tn6000 from Enterococcus casseliflavus 664.1H1 (formerly Enterococcus faecium 664.1H1). FEMS Microbiol Lett (2010) 0.84
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02
Mechanisms of, and barriers to, horizontal gene transfer between bacteria. Nat Rev Microbiol (2005) 6.55
Multiplex PCR assay for simultaneous detection of nine clinically relevant antibiotic resistance genes in Staphylococcus aureus. J Clin Microbiol (2003) 2.32
Generation of an erythromycin-sensitive derivative of Clostridium difficile strain 630 (630Deltaerm) and demonstration that the conjugative transposon Tn916DeltaE enters the genome of this strain at multiple sites. J Med Microbiol (2005) 2.09
Population structure and gene evolution in Saccharomyces cerevisiae. FEMS Yeast Res (2006) 1.98
Release and persistence of extracellular DNA in the environment. Environ Biosafety Res (2007) 1.74
Occurrence and spread of antibiotic resistances in Enterococcus faecium. Int J Food Microbiol (2003) 1.55
Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum. Science (2002) 1.52
Distribution of tetracycline and erythromycin resistance genes among human oral and fecal metagenomic DNA. Microb Drug Resist (2009) 1.35
Antimicrobial susceptibilities of Lactobacillus, Pediococcus and Lactococcus human isolates and cultures intended for probiotic or nutritional use. J Antimicrob Chemother (2007) 1.32
Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile. PLoS One (2011) 1.29
Conjugative transfer of the virulence gene, esp, among isolates of Enterococcus faecium and Enterococcus faecalis. J Antimicrob Chemother (2004) 1.26
PCR-based plasmid typing in Enterococcus faecium strains reveals widely distributed pRE25-, pRUM-, pIP501- and pHTbeta-related replicons associated with glycopeptide resistance and stabilizing toxin-antitoxin systems. FEMS Immunol Med Microbiol (2009) 1.25
The paradoxical population genetics of Plasmodium falciparum. Trends Parasitol (2002) 1.14
Emergence and spread of antibiotic-resistant Gram-positive bacterial pathogens. Int J Med Microbiol (2008) 1.12
Tigecycline-resistant Enterococcus faecalis strain isolated from a German intensive care unit patient. J Antimicrob Chemother (2008) 1.11
A multiresistance megaplasmid pLG1 bearing a hylEfm genomic island in hospital Enterococcus faecium isolates. Int J Med Microbiol (2010) 1.11
Characterization of Tn916S, a Tn916-like element containing the tetracycline resistance determinant tet(S). J Bacteriol (2004) 1.11
Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species. PLoS Pathog (2012) 1.10
Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers. Nat Commun (2013) 1.08
Global spread of the hyl(Efm) colonization-virulence gene in megaplasmids of the Enterococcus faecium CC17 polyclonal subcluster. Antimicrob Agents Chemother (2010) 1.07
Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypes. Genetics (2003) 1.06
Factors affecting the reversal of antimicrobial-drug resistance. Lancet Infect Dis (2009) 1.06
Antibiotic and antiseptic resistance genes are linked on a novel mobile genetic element: Tn6087. J Antimicrob Chemother (2011) 1.02
Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus. J Bacteriol (2009) 1.01
Staphylococcus aureus in dermatology outpatients with special emphasis on community-associated methicillin-resistant strains. J Invest Dermatol (2008) 1.00
Sexual isolation in Acinetobacter baylyi is locus-specific and varies 10,000-fold over the genome. Genetics (2009) 0.99
Performance of three chromogenic VRE screening agars, two Etest(®) vancomycin protocols, and different microdilution methods in detecting vanB genotype Enterococcus faecium with varying vancomycin MICs. Diagn Microbiol Infect Dis (2012) 0.99
Multidrug-resistant bacteria in geriatric clinics, nursing homes, and ambulant care--prevalence and risk factors. Int J Med Microbiol (2013) 0.96
Integrons: Vehicles and pathways for horizontal dissemination in bacteria. Mob Genet Elements (2012) 0.96
Transfer of antibiotic resistance by transformation with eDNA within oral biofilms. FEMS Immunol Med Microbiol (2010) 0.95
In silico analysis of sequenced strains of Clostridium difficile reveals a related set of conjugative transposons carrying a variety of accessory genes. Mob Genet Elements (2012) 0.94
Bacterial diversity in faeces from polar bear (Ursus maritimus) in Arctic Svalbard. BMC Microbiol (2010) 0.94
Occurrence of antibiotic-resistant enterobacteria in agricultural foodstuffs. Mol Nutr Food Res (2004) 0.93
Different antibiotic resistance and sporulation properties within multiclonal Clostridium difficile PCR ribotypes 078, 126, and 033 in a single calf farm. Appl Environ Microbiol (2012) 0.92
Impact of antibiotics on conjugational resistance gene transfer in Staphylococcus aureus in sewage. Environ Microbiol (2003) 0.92
Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation. Appl Environ Microbiol (2014) 0.91
Insight into antimicrobial susceptibility and population structure of contemporary human Enterococcus faecalis isolates from Europe. J Antimicrob Chemother (2011) 0.91
Characterization of tet(32) genes from the oral metagenome. Antimicrob Agents Chemother (2008) 0.90
Effect of khat chewing on periodontal pathogens in subgingival biofilm from chronic periodontitis patients. J Ethnopharmacol (2010) 0.90
A trade-off between the fitness cost of functional integrases and long-term stability of integrons. PLoS Pathog (2012) 0.89
Ecological characterisation of the colonic microbiota in arctic and sub-arctic seals. Microb Ecol (2010) 0.89
Demonstration of conjugative transposon (Tn5397)-mediated horizontal gene transfer between Clostridium difficile and Enterococcus faecalis. Antimicrob Agents Chemother (2010) 0.88
Draft genome sequence of the nontoxigenic Clostridium difficile strain CD37. J Bacteriol (2012) 0.87
Intra- and interspecies genomic transfer of the Enterococcus faecalis pathogenicity island. PLoS One (2011) 0.87
Behavior and target site selection of conjugative transposon Tn916 in two different strains of toxigenic Clostridium difficile. Appl Environ Microbiol (2012) 0.86
Fusobacterium nucleatum enters normal human oral fibroblasts in vitro. J Periodontol (2009) 0.85
Presence of β-lactamases in extended-spectrum-cephalosporin-resistant Salmonella enterica of 30 different serovars in Germany 2005-11. J Antimicrob Chemother (2013) 0.85
Different genetic supports for the tet(S) gene in Enterococci. Antimicrob Agents Chemother (2012) 0.85
The blaIMP-5-carrying integron in a clinical Acinetobacter baumannii strain is flanked by miniature inverted-repeat transposable elements (MITEs). J Antimicrob Chemother (2011) 0.85
Experimental methods for assaying natural transformation and inferring horizontal gene transfer. Methods Enzymol (2005) 0.84
Lack of detectable DNA uptake by bacterial gut isolates grown in vitro and by Acinetobacter baylyi colonizing rodents in vivo. Environ Biosafety Res (2007) 0.84
Characterization of the conjugative transposon Tn6000 from Enterococcus casseliflavus 664.1H1 (formerly Enterococcus faecium 664.1H1). FEMS Microbiol Lett (2010) 0.84
Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants. J Med Chem (2005) 0.83
Evaluation of the antimicrobial effect of super-oxidized water (Sterilox®) and sodium hypochlorite against Enterococcus faecalis in a bovine root canal model. J Appl Oral Sci (2010) 0.82
DNA microarray for the detection of therapeutically relevant antibiotic resistance determinants in clinical isolates of Staphylococcus aureus. Mol Cell Probes (2006) 0.82
Tn916-like elements from human, oral, commensal streptococci possess a variety of antibiotic and antiseptic resistance genes. Int J Antimicrob Agents (2012) 0.82
Separation of DNA-containing organelles from Toxoplasma gondii by CZE. Electrophoresis (2010) 0.82
Characterization of extracellular polymeric matrix, and treatment of Fusobacterium nucleatum and Porphyromonas gingivalis biofilms with DNase I and proteinase K. J Oral Microbiol (2013) 0.82
Minocycline resistance in an oral Streptococcus infantis isolate is encoded by tet(S) on a novel small, low copy number plasmid. FEMS Microbiol Lett (2014) 0.81
TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity. J Antimicrob Chemother (2012) 0.81
Analysis of a Clostridium difficile PCR ribotype 078 100 kilobase island reveals the presence of a novel transposon, Tn6164. BMC Microbiol (2012) 0.81
Characterisation of the plasmidome within Enterococcus faecalis isolated from marginal periodontitis patients in Norway. PLoS One (2013) 0.81
Modeling suggests frequency estimates are not informative for predicting the long-term effect of horizontal gene transfer in bacteria. Environ Biosafety Res (2006) 0.81
Linezolid-resistant E. faecium isolated from an open joint fracture: a report of the first isolate from Italy? Int J Hyg Environ Health (2005) 0.81
Molecular ecological studies on spread of antibiotic resistance genes. Anim Biotechnol (2002) 0.80
Identical miniature inverted repeat transposable elements flank class 1 integrons in clinical isolates of Acinetobacter spp. J Clin Microbiol (2013) 0.79
Controlling antimicrobial resistance through targeted, vaccine-induced replacement of strains. PLoS One (2012) 0.79
Determination of the attP and attB sites of phage CD27 from Clostridium difficile NCTC 12727. J Med Microbiol (2013) 0.79
A tet(S/M) hybrid from CTn6000 and CTn916 recombination. Microbiology (2012) 0.78
Emergence of extended-spectrum β-lactamase (ESBL) CTX-M-8 in Germany. J Antimicrob Chemother (2013) 0.78
Comparison of antibiotic resistance, biofilm formation and conjugative transfer of Staphylococcus and Enterococcus isolates from International Space Station and Antarctic Research Station Concordia. Microb Ecol (2013) 0.78
Linkage of a novel mercury resistance operon with streptomycin resistance on a conjugative plasmid in Enterococcus faecium. Plasmid (2004) 0.78
Various pathways leading to the acquisition of antibiotic resistance by natural transformation. Mob Genet Elements (2012) 0.78
DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum. Mol Biochem Parasitol (2003) 0.78
Costly Class-1 integrons and the domestication of the the functional integrase. Mob Genet Elements (2013) 0.77
Transposon mutagenesis in Clostridium difficile. Methods Mol Biol (2010) 0.77
Nucleic acid isolation from ecological samples--vertebrate gut flora. Methods Enzymol (2005) 0.77
An assessment of the potential of herbivorous insect gut bacteria to develop competence for natural transformation. Environ Biosafety Res (2007) 0.77
Complete genome sequence of the porcine isolate Enterococcus faecalis D32. J Bacteriol (2012) 0.76
Cross-transmission rates of enterococcal isolates among newborns in a neonatal intensive care unit. Pediatr Rep (2012) 0.75