Published in Angiogenesis on July 10, 2013
Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer | NCT01554969
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The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer. Invest New Drugs (2014) 0.87
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HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy. Oncotarget (2014) 0.83
Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition. Oncotarget (2015) 0.82
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A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer. Clin Cancer Res (2013) 1.90
A probability sample for monitoring the HIV-infected population in care in the U.S. and in selected states. Open AIDS J (2012) 1.90
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Novel c-CBL and CBL-b ubiquitin ligase mutations in human acute myeloid leukemia. Blood (2007) 1.83
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Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy. Mol Cancer Ther (2011) 1.74
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Targeted inhibition of the molecular chaperone Hsp90 overcomes ALK inhibitor resistance in non-small cell lung cancer. Cancer Discov (2013) 1.63
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Critical role of endothelial cell activation in hypoxia-induced vasoocclusion in transgenic sickle mice. Am J Physiol Heart Circ Physiol (2005) 1.57
Frequent mutations of human Mad2, but not Bub1, in gastric cancers cause defective mitotic spindle checkpoint. Mutat Res (2005) 1.51
Willingness of US men who have sex with men (MSM) to participate in Couples HIV Voluntary Counseling and Testing (CVCT). PLoS One (2012) 1.51
Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction. Cardiovasc Res (2004) 1.49
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Central venous catheter care for the patient with cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol (2013) 1.46
Knowledge and use of preexposure and postexposure prophylaxis among attendees of Minority Gay Pride events, 2005 through 2006. J Acquir Immune Defic Syndr (2007) 1.46
Prognostic relevance of Id-1 expression in patients with resectable esophageal squamous cell carcinoma. Ann Thorac Surg (2012) 1.46
Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. Mol Cancer Ther (2008) 1.46
Prevalence of cervical cancer screening of HIV-infected women in the United States. J Acquir Immune Defic Syndr (2009) 1.45
Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation (2004) 1.42
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Recurrent rectal cancer causing lumbosacral plexopathy with perineural spread to the spinal nerves and the sciatic nerve: an anatomic explanation. Clin Anat (2014) 1.40
Rapid HIV screening: missed opportunities for HIV diagnosis and prevention. J Clin Virol (2012) 1.38
A Multidisciplinary Approach to Perianal and Intra-Abdominal Infections in the Neutropenic Cancer Patient. Oncology (Williston Park) (2015) 1.38
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Sexual agreements in the partnerships of internet-using men who have sex with men. AIDS Care (2012) 1.34
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Discussion of HIV status by serostatus and partnership sexual risk among internet-using MSM in the United States. J Acquir Immune Defic Syndr (2012) 1.26
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HIV transmission in a state prison system, 1988-2005. PLoS One (2009) 1.24
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Enrollment of racial/ethnic minorities in NIAID-funded networks of HIV vaccine trials in the United States, 1988 to 2002. Public Health Rep (2005) 1.22
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Targeting KRAS-mutant non-small cell lung cancer with the Hsp90 inhibitor ganetespib. Mol Cancer Ther (2012) 1.22
Modified FOLFIRINOX regimen with improved safety and maintained efficacy in pancreatic adenocarcinoma. Pancreas (2013) 1.21
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Exploitation of protein kinase C: a useful target for cancer therapy. Cancer Treat Rev (2008) 1.21
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Genetic characterization of a new cytoplasmic male sterility system (hau) in Brassica juncea and its transfer to B. napus. Theor Appl Genet (2007) 1.19
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Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors. Cancer Res (2010) 1.17
Alternative HIV testing methods among populations at high risk for HIV infection. Public Health Rep (2003) 1.17
Enhancement of antitumor immunity of dendritic cells pulsed with heat-treated tumor lysate in murine pancreatic cancer. Immunol Lett (2005) 1.17
Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells. Breast Cancer Res Treat (2009) 1.15
Elastin-mimetic protein polymers capable of physical and chemical crosslinking. Biomaterials (2008) 1.15
Willingness to Take a Free Home HIV Test and Associated Factors among Internet-Using Men Who Have Sex with Men. J Int Assoc Physicians AIDS Care (Chic) (2011) 1.14
Willingness of men who have sex with men (MSM) in the United States to be circumcised as adults to reduce the risk of HIV infection. PLoS One (2008) 1.14
HIV risk behaviors and testing history in historically black college and university settings. Public Health Rep (2009) 1.14
Molecular mechanisms underlying the divergent roles of SPARC in human carcinogenesis. Carcinogenesis (2014) 1.14
Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction. J Am Coll Cardiol (2003) 1.13
Risk factors for rising incidence of esophageal and gastric cardia adenocarcinoma. J Gastrointest Cancer (2013) 1.13
DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication. Blood (2008) 1.12
Participant retention in clinical trials of candidate HIV vaccines. J Acquir Immune Defic Syndr (2005) 1.12
Mitochondrial electron transport is the cellular target of the oncology drug elesclomol. PLoS One (2012) 1.12
Fidelity and evolution of recurrent FSGS in renal allografts. J Am Soc Nephrol (2008) 1.11
Enhancing retention of an Internet-based cohort study of men who have sex with men (MSM) via text messaging: randomized controlled trial. J Med Internet Res (2013) 1.10
High prevalence of sexual concurrency and concurrent unprotected anal intercourse across racial/ethnic groups among a national, Web-based study of men who have sex with men in the United States. Sex Transm Dis (2012) 1.10
Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol (2009) 1.10
A large insertion in bHLH transcription factor BrTT8 resulting in yellow seed coat in Brassica rapa. PLoS One (2012) 1.10
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Circulating angiogenic cytokines in patients with advanced non-small cell lung cancer: correlation with treatment response and survival. Cancer Invest (2005) 1.09