Published in Nature on August 16, 1990
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Cardiomyocytes can be generated from marrow stromal cells in vitro. J Clin Invest (1999) 5.30
Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol Cell Biol (1991) 4.42
Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site. Mol Cell Biol (1991) 3.54
HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors. Mol Cell Biol (1992) 2.72
Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila. EMBO J (1991) 2.04
Inefficient homooligomerization contributes to the dependence of myogenin on E2A products for efficient DNA binding. Mol Cell Biol (1991) 1.79
Repositioning of muscle-specific genes relative to the periphery of SC-35 domains during skeletal myogenesis. Mol Biol Cell (2003) 1.66
The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development. J Cell Biol (1991) 1.60
Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. Proc Natl Acad Sci U S A (1991) 1.53
MyoD and the regulation of myogenesis by helix-loop-helix proteins. J Clin Invest (1991) 1.52
Possible cross-regulation of phosphate and sulfate metabolism in Saccharomyces cerevisiae. Genetics (1992) 1.48
The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription. Mol Cell Biol (1992) 1.44
DNA binding and transcriptional regulatory activity of mammalian achaete-scute homologous (MASH) proteins revealed by interaction with a muscle-specific enhancer. Proc Natl Acad Sci U S A (1992) 1.43
Cyclic amplification and selection of targets for multicomponent complexes: myogenin interacts with factors recognizing binding sites for basic helix-loop-helix, nuclear factor 1, myocyte-specific enhancer-binding factor 2, and COMP1 factor. Proc Natl Acad Sci U S A (1992) 1.41
Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development. EMBO J (1995) 1.39
Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle. Mol Cell Biol (1993) 1.34
In vivo characterization of the Saccharomyces cerevisiae centromere DNA element I, a binding site for the helix-loop-helix protein CPF1. Mol Cell Biol (1991) 1.33
Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4. EMBO J (1999) 1.32
Fiber-type-specific transcription of the troponin I slow gene is regulated by multiple elements. Mol Cell Biol (1999) 1.24
The MyoD family of myogenic factors is regulated by electrical activity: isolation and characterization of a mouse Myf-5 cDNA. Nucleic Acids Res (1992) 1.24
Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema. PLoS Comput Biol (2013) 1.11
The four human muscle regulatory helix-loop-helix proteins Myf3-Myf6 exhibit similar hetero-dimerization and DNA binding properties. Nucleic Acids Res (1991) 1.09
Domains outside of the DNA-binding domain impart target gene specificity to myogenin and MRF4. Mol Cell Biol (1991) 1.02
NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression. EMBO J (2004) 1.02
Co-operativity of functional domains in the muscle-specific transcription factor Myf-5. EMBO J (1992) 1.00
A Postnatal Pax7 Progenitor Gives Rise to Pituitary Adenomas. Genes Cancer (2010) 0.99
The MRF4 activation domain is required to induce muscle-specific gene expression. Mol Cell Biol (1992) 0.98
VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucleic Acids Res (2004) 0.94
Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes. EMBO J (2004) 0.93
Secretion and transcriptional regulation of transforming growth factor-beta 3 during myogenesis. Mol Cell Biol (1991) 0.93
Rhabdomyosarcomas do not contain mutations in the DNA binding domains of myogenic transcription factors. J Clin Invest (1994) 0.91
Dimerization through the helix-loop-helix motif enhances phosphorylation of the transcription activation domains of myogenin. Mol Cell Biol (1994) 0.84
Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation. Dev Cell (2016) 0.81
Developing skeletal muscle cells express functional muscarinic acetylcholine receptors coupled to different intracellular signaling systems. Br J Pharmacol (2005) 0.79
Expression of myogenic regulatory factors in the muscle-derived electric organ of Sternopygus macrurus. J Exp Biol (2008) 0.79
Identification of the C-terminal activation domain of the NeuroD-related factor (NDRF). Nucleic Acids Res (2000) 0.79
Influence of promoter potency on the transcriptional effects of YY1, SRF and Msx-1 in transient transfection analysis. Nucleic Acids Res (1998) 0.78
Differentiation-dependent mechanisms of transcriptional regulation of the catalytic subunit of phosphorylase kinase. Biochem J (2002) 0.75
MyoD or Myf-5 is required for the formation of skeletal muscle. Cell (1993) 7.14
A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts. EMBO J (1989) 6.37
Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell (1996) 4.55
Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death. Cell (1992) 3.65
Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12. EMBO J (1990) 3.16
ABC of intensive care. Withdrawal of treatment. BMJ (1999) 2.96
Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products. EMBO J (1989) 2.88
NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. EMBO J (2000) 2.76
Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo. Development (1991) 2.60
Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development (1999) 2.48
Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. Development (1994) 2.45
Genomic DNA differences between pathogenic and nonpathogenic Entamoeba histolytica. Proc Natl Acad Sci U S A (1989) 2.23
Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet (2000) 2.22
Gene targeting the myf-5 locus with nlacZ reveals expression of this myogenic factor in mature skeletal muscle fibres as well as early embryonic muscle. Dev Dyn (1996) 2.09
A role for FGF-6 in skeletal muscle regeneration. Genes Dev (1997) 1.79
Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development (1999) 1.68
Muscle differentiation: more complexity to the network of myogenic regulators. Curr Opin Genet Dev (1998) 1.68
BMP2 is required for early heart development during a distinct time period. Mech Dev (2000) 1.67
Netrin 1 is required for semicircular canal formation in the mouse inner ear. Development (2000) 1.65
Promoter upstream elements of the chicken cardiac myosin light-chain 2-A gene interact with trans-acting regulatory factors for muscle-specific transcription. Mol Cell Biol (1989) 1.63
Alpha 1-antitrypsin Pi-types in 965 COPD patients. Chest (1986) 1.61
The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development. J Cell Biol (1991) 1.60
Epidemiology and morbidity of scabies and pediculosis capitis in resource-poor communities in Brazil. Br J Dermatol (2005) 1.57
A highly conserved enhancer downstream of the human MLC1/3 locus is a target for multiple myogenic determination factors. Nucleic Acids Res (1990) 1.50
Physical activity and memory functions: are neurotrophins and cerebral gray matter volume the missing link? Neuroimage (2009) 1.48
The down-regulation of the chicken cytoplasmic beta actin during myogenic differentiation does not require the gene promoter but involves the 3' end of the gene. Nucleic Acids Res (1988) 1.46
Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development. EMBO J (1995) 1.39
Pericardial placement of a pulmonary artery catheter. Anaesthesia (1998) 1.38
Inhibition of muscle differentiation by the adenovirus E1a protein: repression of the transcriptional activating function of the HLH protein Myf-5. Genes Dev (1992) 1.35
Developmental patterns in the expression of Myf5, MyoD, myogenin, and MRF4 during myogenesis. New Biol (1991) 1.32
MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice. Development (1994) 1.30
Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. Dev Biol (2000) 1.27
BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos. Mech Dev (1998) 1.25
Emergency medicine at a large rock festival. J Accid Emerg Med (1996) 1.21
Myogenin's functions do not overlap with those of MyoD or Myf-5 during mouse embryogenesis. Dev Biol (1995) 1.20
An exported protein of Plasmodium falciparum is synthesized as an integral membrane protein. Mol Biochem Parasitol (1991) 1.20
Myf-5 and myoD genes are activated in distinct mesenchymal stem cells and determine different skeletal muscle cell lineages. EMBO J (1996) 1.19
The primary structure of the human ribosomal protein S6 derived from a cloned cDNA. J Biol Chem (1988) 1.16
Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging. J Physiol Pharmacol (2008) 1.15
Nkx5-1 controls semicircular canal formation in the mouse inner ear. Development (1998) 1.13
NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos. Dev Genes Evol (2000) 1.12
The alkali light chains of human smooth and nonmuscle myosins are encoded by a single gene. Tissue-specific expression by alternative splicing pathways. J Biol Chem (1989) 1.12
The myogenin gene is activated during myocyte differentiation by pre-existing, not newly synthesized transcription factor MEF-2. J Biol Chem (1994) 1.11
The four human muscle regulatory helix-loop-helix proteins Myf3-Myf6 exhibit similar hetero-dimerization and DNA binding properties. Nucleic Acids Res (1991) 1.09
Sequence analysis of the cloned mRNA coding for glyceraldehyde-3-phosphate dehydrogenase from chicken heart muscle. Eur J Biochem (1983) 1.05
Nkx2-9 is a novel homeobox transcription factor which demarcates ventral domains in the developing mouse CNS. Mech Dev (1998) 1.05
ES-cells carrying two inactivated myf-5 alleles form skeletal muscle cells: activation of an alternative myf-5-independent differentiation pathway. Dev Biol (1994) 1.04
The interaction of nuclear proteins with essential promoter element of the chicken cardiac myosin light chain 2 gene is involved in muscle-specific transcription. FEBS Lett (1988) 1.01
cAMP-dependent protein kinase represses myogenic differentiation and the activity of the muscle-specific helix-loop-helix transcription factors Myf-5 and MyoD. J Biol Chem (1993) 1.01
A novel NK-related mouse homeobox gene: expression in central and peripheral nervous structures during embryonic development. Dev Biol (1994) 1.01
Occurrence and biosynthesis of ribothymidine in tRNAs of B. subtilis. FEBS Lett (1975) 1.00
Co-operativity of functional domains in the muscle-specific transcription factor Myf-5. EMBO J (1992) 1.00
Different MRF4 knockout alleles differentially disrupt Myf-5 expression: cis-regulatory interactions at the MRF4/Myf-5 locus. Dev Biol (1997) 1.00
Expression of members of the myf gene family in human rhabdomyosarcomas. Br J Cancer (1991) 1.00
Purification and characterization of tRNAMet-f, tRNAPhe and tRNATyr2 from Baccillus subtilis. Biochim Biophys Acta (1976) 1.00
FGFs control the patterning of the inner ear but are not able to induce the full ear program. Mech Dev (2001) 1.00
Biosynthetic pathway of ribothymidine in B. subtilis and M. lysodeikticus involving different coenzymes for transfer RNA and ribosomal RNA. Nucleic Acids Res (1975) 0.98
Primary structure of Bacillus subtilis tRNAsTyr. Biochem Biophys Res Commun (1980) 0.98
Transcription of the muscle regulatory gene Myf4 is regulated by serum components, peptide growth factors and signaling pathways involving G proteins. J Cell Biol (1991) 0.97
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The nucleotide sequence of phenylalanine tRNA from Bacillus subtilis. Nucleic Acids Res (1977) 0.96
Activated raf kinase inhibits muscle cell differentiation through a MEF2-dependent mechanism. J Cell Sci (2000) 0.95
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Identification of the functional promoter regions in the human gene encoding the myosin alkali light chains MLC1 and MLC3 of fast skeletal muscle. J Biol Chem (1989) 0.95
In vitro biosynthesis and membrane translocation of the serine rich protein of Plasmodium falciparum. Mol Biochem Parasitol (1990) 0.95
S-Adenosylmethionine and tetrahydrofolate-dependent methylation of tRNA in Bacillus subtilis. Incomplete methylations caused by trimethoprim, pactamycin, or chloramphenicol. Arch Biochem Biophys (1976) 0.94
Inhibition of the tetrahydrofolate-dependent biosynthesis of ribothymidine in tRNAs of B. subtilis and M. lysodeikticus by trimethoprim. FEBS Lett (1975) 0.93
7-Methylguanine specific tRNA-methyltransferase from Escherichia coli. Nucleic Acids Res (1976) 0.92
Transcriptional activation of the myogenin gene by MEF2-mediated recruitment of myf5 is inhibited by adenovirus E1A protein. Biochem Biophys Res Commun (1999) 0.91
The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development. Dev Dyn (1997) 0.91
Isolation and characterization of the chicken cardiac myosin light chain (L-2A) gene. Evidence for two additional N-terminal amino acids. J Biol Chem (1985) 0.91
Distinct temporal expression of mouse Nkx-5.1 and Nkx-5.2 homeobox genes during brain and ear development. Mech Dev (1995) 0.90
Tetrahydrofolate-dependent 5-methyluracil-tRNA transferase activity in B. subtilis. FEBS Lett (1975) 0.89
Initial steps of myogenesis in somites are independent of influence from axial structures. Development (1994) 0.89
Craniosynostosis. Clin Radiol (2012) 0.89
Tetrahydrofolate-dependent biosynthesis of ribothymidine in transfer ribonucleic acids of Gram-positive bacteria. J Bacteriol (1977) 0.89
cMeso-1, a novel bHLH transcription factor, is involved in somite formation in chicken embryos. Dev Biol (1998) 0.88
The homeobox gene NKX3.2 is a target of left-right signalling and is expressed on opposite sides in chick and mouse embryos. Curr Biol (1999) 0.88
Cloning, partial sequencing, and expression of glyceraldehyde-3-phosphate dehydrogenase gene in chick embryonic heart muscle cells. J Biol Chem (1982) 0.88