Published in Radiother Oncol on July 12, 2013
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The biological effectiveness of antiproton irradiation. Radiother Oncol (2006) 1.66
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Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations. PLoS Genet (2006) 1.50
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Tumor hypoxia predicts biochemical failure following radiotherapy for clinically localized prostate cancer. Clin Cancer Res (2012) 1.41
Partial volume rat lung irradiation: the protective/mitigating effects of Eukarion-189, a superoxide dismutase-catalase mimetic. Radiother Oncol (2006) 1.39
Acute hypoxia enhances spontaneous lymph node metastasis in an orthotopic murine model of human cervical carcinoma. Cancer Res (2004) 1.38
Partial volume rat lung irradiation: temporal fluctuations of in-field and out-of-field DNA damage and inflammatory cytokines following irradiation. Int J Radiat Biol (2005) 1.35
Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response. Breast Cancer Res (2013) 1.33
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Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3. Radiother Oncol (2009) 1.27
Citrulline: a physiologic marker enabling quantitation and monitoring of epithelial radiation-induced small bowel damage. Int J Radiat Oncol Biol Phys (2003) 1.24
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response. Clin Cancer Res (2013) 1.24
The hypoxic proteome is influenced by gene-specific changes in mRNA translation. Radiother Oncol (2005) 1.22
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Late residual gamma-H2AX foci in murine skin are dose responsive and predict radiosensitivity in vivo. Radiat Res (2010) 1.17
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Hypoxia and metastasis in breast cancer. Breast Dis (2007) 1.11
Mitigation of radiation-induced lung injury by genistein and EUK-207. Int J Radiat Biol (2011) 1.10
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Autophagy is required during cycling hypoxia to lower production of reactive oxygen species. Radiother Oncol (2009) 1.08
Interstitial fluid pressure, vascularity and metastasis in ectopic, orthotopic and spontaneous tumours. BMC Cancer (2008) 1.07
Polarographic electrode study of tumor oxygenation in clinically localized prostate cancer. Int J Radiat Oncol Biol Phys (2004) 1.07
Radiation dose prescription for non-small-cell lung cancer according to normal tissue dose constraints: an in silico clinical trial. Int J Radiat Oncol Biol Phys (2008) 1.07
Genistein can mitigate the effect of radiation on rat lung tissue. Radiat Res (2010) 1.06
A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures. PLoS One (2011) 1.05
Phosphorylation of eIF2alpha is required for mRNA translation inhibition and survival during moderate hypoxia. Radiother Oncol (2007) 1.05
Salen Mn complexes mitigate radiation injury in normal tissues. Anticancer Agents Med Chem (2011) 1.03
Long-term performance of interstial fluid pressure and hypoxia as prognostic factors in cervix cancer. Radiother Oncol (2006) 1.03
Hypoxia-induced expression of carbonic anhydrase 9 is dependent on the unfolded protein response. J Biol Chem (2009) 1.03
Development of a flexible and potent hypoxia-inducible promoter for tumor-targeted gene expression in attenuated Salmonella. Cancer Biol Ther (2006) 1.03
Nutlin-3 radiosensitizes hypoxic prostate cancer cells independent of p53. Mol Cancer Ther (2008) 1.03
Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis. Cancer Res (2004) 1.02
Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model. Radiother Oncol (2009) 1.02
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Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors. Radiother Oncol (2007) 1.00
High-resolution in-vivo analysis of normal brain response to cranial irradiation. PLoS One (2012) 1.00
Hypoxia and regulation of messenger RNA translation. Methods Enzymol (2007) 0.98
MicroRNA-196b regulates the homeobox B7-vascular endothelial growth factor axis in cervical cancer. PLoS One (2013) 0.98
Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3. Clin Cancer Res (2013) 0.98
A fluorescent orthotopic model of metastatic cervical carcinoma. Clin Exp Metastasis (2004) 0.98
Effects of genistein following fractionated lung irradiation in mice. Radiother Oncol (2009) 0.97
hMMS2 serves a redundant role in human PCNA polyubiquitination. BMC Mol Biol (2008) 0.97
The mTOR target 4E-BP1 contributes to differential protein expression during normoxia and hypoxia through changes in mRNA translation efficiency. Proteomics (2008) 0.96
Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation. Int J Radiat Oncol Biol Phys (2002) 0.96
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Effects of radiotherapy and chemotherapy on angiogenesis and leukocyte infiltration in rectal cancer. Int J Radiat Oncol Biol Phys (2006) 0.95
The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment. Radiother Oncol (2009) 0.95
Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors. Lab Invest (2009) 0.95
AMPK regulates metabolism and survival in response to ionizing radiation. Radiother Oncol (2011) 0.94
PRIMA-1(met) radiosensitizes prostate cancer cells independent of their MTp53-status. Radiother Oncol (2008) 0.94
Expression of EGFR variant vIII promotes both radiation resistance and hypoxia tolerance. Radiother Oncol (2007) 0.94
Activation of Src and Src-associated signaling pathways in relation to hypoxia in human cancer xenograft models. Int J Cancer (2009) 0.93
Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis. Radiother Oncol (2006) 0.93
Effect of radiation and cell implantation on wound healing in a rat model. J Surg Oncol (2003) 0.92
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS. Proc Natl Acad Sci U S A (2013) 0.92
Intra-voxel heterogeneity influences the dose prescription for dose-painting with radiotherapy: a modelling study. Phys Med Biol (2009) 0.92
In vivo optical imaging of tumor and microvascular response to ionizing radiation. PLoS One (2012) 0.90
Hedgehog pathway signaling in cervical carcinoma and outcome after chemoradiation. Cancer (2011) 0.90
Potential and limitations of bacterial-mediated cancer therapy. Front Biosci (2007) 0.90
Impact of supervised gene signatures of early hypoxia on patient survival. Radiother Oncol (2007) 0.90
Binding of cetuximab to the EGFRvIII deletion mutant and its biological consequences in malignant glioma cells. Radiother Oncol (2009) 0.89
Beta-catenin is a mediator of the response of fibroblasts to irradiation. Am J Pathol (2008) 0.89
Effects of the vascular disrupting agent ZD6126 on interstitial fluid pressure and cell survival in tumors. Cancer Res (2006) 0.89
Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer. Cancer (2011) 0.89
No apoptotic endothelial cells in irradiated intestine: regarding Schuller et al. (Int J Radiat Oncol Biol Phys 2007;68:205-210). Int J Radiat Oncol Biol Phys (2008) 0.89
Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies. Drug Resist Updat (2006) 0.89
Nuclear E-cadherin and VHL immunoreactivity are prognostic indicators of clear-cell renal cell carcinoma. Lab Invest (2007) 0.89
Development and evaluation of a cetuximab-based imaging probe to target EGFR and EGFRvIII. Radiother Oncol (2007) 0.88
Hypoxia as a biomarker for radioresistant cancer stem cells. Int J Radiat Biol (2014) 0.88