Published in BMC Syst Biol on July 19, 2013
Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways. BMC Syst Biol (2013) 0.76
Metaproteomics and metabolomics analyses of chronically petroleum-polluted sites reveal the importance of general anaerobic processes uncoupled with degradation. Proteomics (2015) 0.75
Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics (2003) 100.88
A model for random sampling and estimation of relative protein abundance in shotgun proteomics. Anal Chem (2004) 19.20
Regulation of cancer cell metabolism. Nat Rev Cancer (2011) 15.44
XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem (2006) 15.00
Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci U S A (2007) 11.46
AmiGO: online access to ontology and annotation data. Bioinformatics (2008) 10.77
Computational prediction of human metabolic pathways from the complete human genome. Genome Biol (2004) 7.52
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks. Nat Biotechnol (2000) 6.74
The population genetics of ecological specialization in evolving Escherichia coli populations. Nature (2000) 5.80
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science (2010) 5.44
Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol (2012) 5.19
Cystinosis. N Engl J Med (2002) 4.51
The model organism as a system: integrating 'omics' data sets. Nat Rev Mol Cell Biol (2006) 3.69
Predicting selective drug targets in cancer through metabolic networks. Mol Syst Biol (2011) 3.65
Clinical applications of metabolomics in oncology: a review. Clin Cancer Res (2009) 2.91
Genome-scale thermodynamic analysis of Escherichia coli metabolism. Biophys J (2005) 2.70
Homocysteine and folate as risk factors for dementia and Alzheimer disease. Am J Clin Nutr (2005) 2.16
Molecular basis of sulfite oxidase deficiency from the structure of sulfite oxidase. Cell (1997) 2.12
MassTRIX: mass translator into pathways. Nucleic Acids Res (2008) 2.05
Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PLoS Comput Biol (2012) 1.94
Combinatorial complexity of pathway analysis in metabolic networks. Mol Biol Rep (2002) 1.92
Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model. Bioinformatics (2010) 1.65
Physiological control of metabolic flux: the requirement for multisite modulation. Biochem J (1995) 1.61
A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast. Biochem J (1992) 1.60
Integration of metabolome data with metabolic networks reveals reporter reactions. Mol Syst Biol (2006) 1.60
MetExplore: a web server to link metabolomic experiments and genome-scale metabolic networks. Nucleic Acids Res (2010) 1.47
Evolution of cross-feeding in microbial populations. Am Nat (2004) 1.46
Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. Biochim Biophys Acta (2010) 1.38
Towards a genome-scale kinetic model of cellular metabolism. BMC Syst Biol (2010) 1.34
Hallervorden-Spatz disease: cysteine accumulation and cysteine dioxygenase deficiency in the globus pallidus. Ann Neurol (1985) 1.26
Total serum homocysteine in senile dementia of Alzheimer type. Int J Geriatr Psychiatry (1998) 1.25
A universal method for achieving increases in metabolite production. Eur J Biochem (1993) 1.25
TICL--a web tool for network-based interpretation of compound lists inferred by high-throughput metabolomics. FEBS J (2009) 1.21
Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials? Pharmacogenomics (2006) 1.16
Approximative kinetic formats used in metabolic network modeling. Biotechnol Bioeng (2005) 1.13
A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease. Neurobiol Aging (2006) 1.06
Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease. Neurobiol Dis (2007) 1.01
Tracer-based metabolomics: concepts and practices. Clin Biochem (2010) 0.98
Lysine acetylation in obesity, diabetes and metabolic disease. Immunol Cell Biol (2011) 0.98
Urine formaldehyde level is inversely correlated to mini mental state examination scores in senile dementia. Neurobiol Aging (2009) 0.98
Use of reconstituted metabolic networks to assist in metabolomic data visualization and mining. Metabolomics (2010) 0.97
Cerebral atrophy and nephropathic cystinosis. Arch Dis Child (1986) 0.97
Path finding methods accounting for stoichiometry in metabolic networks. Genome Biol (2011) 0.96
Histological distribution of class III alcohol dehydrogenase in human brain. Brain Res (2000) 0.96
Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease. Brain Res (2004) 0.91
Isolated sulfite oxidase deficiency: MR imaging features. AJNR Am J Neuroradiol (2002) 0.88
Construction of an E. Coli genome-scale atom mapping model for MFA calculations. Biotechnol Bioeng (2011) 0.85
Altered brain lipid composition in cyclooxygenase-2 knockout mouse. J Lipid Res (2007) 0.83
Activity of phosphatidylethanolamine-N-methyltransferase in brain affected by Alzheimer's disease. Neurochem Int (1999) 0.81
Sexually dimorphic activation of liver and brain phosphatidylethanolamine N-methyltransferase by dietary choline deficiency. Neurochem Res (1998) 0.80
A strategy to calculate the patterns of nutrient consumption by microorganisms applying a two-level optimisation principle to reconstructed metabolic networks. J Biol Phys (2008) 0.80
Integrating tracer-based metabolomics data and metabolic fluxes in a linear fashion via Elementary Carbon Modes. Metab Eng (2012) 0.80
Age-related changes in central nervous system phosphatidylserine decarboxylase activity. J Neurosci Res (2002) 0.80
A case of claimed persistent neuropsychological sequelae of chronic formaldehyde exposure: clinical, psychometric, and functional findings. Arch Clin Neuropsychol (2001) 0.79
An optimization model for metabolic pathways. Bioinformatics (2009) 0.78
Inhibition of pyruvate kinase activity by cystine in brain cortex of rats. Brain Res (2004) 0.78
Computing the shortest elementary flux modes in genome-scale metabolic networks. Bioinformatics (2009) 1.54
Joint analysis of miRNA and mRNA expression data. Brief Bioinform (2012) 1.21
Path finding methods accounting for stoichiometry in metabolic networks. Genome Biol (2011) 0.96
Bioinformatic progress and applications in metaproteogenomics for bridging the gap between genomic sequences and metabolic functions in microbial communities. Proteomics (2013) 0.88
Selection of human tissue-specific elementary flux modes using gene expression data. Bioinformatics (2013) 0.85
Recovering metabolic pathways via optimization. Bioinformatics (2006) 0.85
Refining carbon flux paths using atomic trace data. Bioinformatics (2013) 0.81
Integrating tracer-based metabolomics data and metabolic fluxes in a linear fashion via Elementary Carbon Modes. Metab Eng (2012) 0.80
Advances in network-based metabolic pathway analysis and gene expression data integration. Brief Bioinform (2014) 0.79
Integrating gene and protein expression data with genome-scale metabolic networks to infer functional pathways. BMC Syst Biol (2013) 0.76
Do elementary flux modes combine linearly at the "atomic" level?: integrating tracer-based metabolomics data and elementary flux modes. Biosystems (2011) 0.75