Published in Anal Chem on February 01, 2006
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Gene and metabolite regulatory network analysis of early developing fruit tissues highlights new candidate genes for the control of tomato fruit composition and development. Plant Physiol (2009) 1.50
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Global profiling strategies for mapping dysregulated metabolic pathways in cancer. Cell Metab (2012) 1.28
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Fruit-surface flavonoid accumulation in tomato is controlled by a SlMYB12-regulated transcriptional network. PLoS Genet (2009) 1.24
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ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proc Natl Acad Sci U S A (2013) 1.18
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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A (2009) 5.86
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science (2007) 5.49
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Structure of the human histamine H1 receptor complex with doxepin. Nature (2011) 3.48
Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem Biol (2010) 3.38
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XCMS Online: a web-based platform to process untargeted metabolomic data. Anal Chem (2012) 3.24
Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry (2004) 3.10
Metabolic oxidation regulates embryonic stem cell differentiation. Nat Chem Biol (2010) 3.06
Pocketome via comprehensive identification and classification of ligand binding envelopes. Mol Cell Proteomics (2005) 2.83
Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin. Nat Chem Biol (2012) 2.76
Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. J Am Chem Soc (2010) 2.62
Microbial metalloproteomes are largely uncharacterized. Nature (2010) 2.62
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Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin Chem (2007) 2.31
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Res (2011) 2.30
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Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure (2011) 2.11
Clathrate nanostructures for mass spectrometry. Nature (2007) 2.10
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Nuclear hormone receptor targeted virtual screening. J Med Chem (2003) 2.05
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. J Mol Recognit (2009) 2.05
Colonization-induced host-gut microbial metabolic interaction. MBio (2011) 2.04
The expanding role of mass spectrometry in metabolite profiling and characterization. Chembiochem (2005) 2.04
Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal Chem (2006) 2.04
Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. J Med Chem (2010) 1.88
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum. Anal Chem (2006) 1.81
Identification of protein-protein interaction sites from docking energy landscapes. J Mol Biol (2004) 1.79
Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis. J Virol (2004) 1.77
Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. Anal Chem (2013) 1.76
Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Anal Chem (2007) 1.75
The liganding of glycolipid transfer protein is controlled by glycolipid acyl structure. PLoS Biol (2006) 1.70
Optimal docking area: a new method for predicting protein-protein interaction sites. Proteins (2005) 1.69
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Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. J Clin Invest (2008) 1.66
Statistical analysis and prediction of protein-protein interfaces. Proteins (2005) 1.65
ICM-DISCO docking by global energy optimization with fully flexible side-chains. Proteins (2003) 1.63
Sepsis plasma protein profiling with immunodepletion, three-dimensional liquid chromatography tandem mass spectrometry, and spectrum counting. J Proteome Res (2006) 1.61
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Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking. Proc Natl Acad Sci U S A (2003) 1.53
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