PubRank

Beate Lanske

Author PubWeight™ 68.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol Cell Biol 2007 3.73
2 Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice. Matrix Biol 2004 3.23
3 Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J 2006 2.99
4 Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J 2010 2.91
5 Reversal of mineral ion homeostasis and soft-tissue calcification of klotho knockout mice by deletion of vitamin D 1alpha-hydroxylase. Kidney Int 2009 2.39
6 PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development 2002 2.19
7 Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus. Nat Genet 2006 2.11
8 In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis. FASEB J 2008 2.03
9 Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis. Development 2007 1.97
10 Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone. Proc Natl Acad Sci U S A 2007 1.85
11 Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest 2005 1.82
12 The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis. J Endocrinol 2007 1.81
13 Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals. Am J Pathol 2006 1.75
14 Genetic evidence of serum phosphate-independent functions of FGF-23 on bone. PLoS Genet 2008 1.63
15 Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice. Trends Mol Med 2006 1.60
16 Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. J Pathol 2005 1.57
17 Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice. Matrix Biol 2006 1.56
18 PTH ablation ameliorates the anomalies of Fgf23-deficient mice by suppressing the elevated vitamin D and calcium levels. Endocrinology 2011 1.54
19 FGF-23-Klotho signaling stimulates proliferation and prevents vitamin D-induced apoptosis. J Cell Biol 2008 1.53
20 Stanniocalcin 2 is associated with ectopic calcification in α-klotho mutant mice and inhibits hyperphosphatemia-induced calcification in aortic vascular smooth muscle cells. Bone 2012 1.43
21 FGF-23, vitamin D and calcification: the unholy triad. Nephrol Dial Transplant 2005 1.35
22 Skeletal abnormalities in Pth-null mice are influenced by dietary calcium. Endocrinology 2003 1.26
23 In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levels. Circ Cardiovasc Genet 2009 1.26
24 Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes. Dev Cell 2010 1.21
25 Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype. J Bone Miner Res 2005 1.12
26 Does Fgf23-klotho activity influence vascular and soft tissue calcification through regulating mineral ion metabolism? Kidney Int 2008 1.06
27 Loss of Indian Hedgehog activates multiple aspects of a wound healing response in the mouse intestine. Gastroenterology 2010 1.05
28 Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling. Biol Reprod 2010 1.03
29 Biological activity of FGF-23 fragments. Pflugers Arch 2007 1.03
30 FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH. J Bone Miner Res 2011 1.02
31 Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice. Arthritis Res Ther 2014 1.01
32 Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation. Blood 2008 1.00
33 FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway. Bone 2012 0.99
34 Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice. J Bone Miner Res 2014 0.99
35 FGF23 promotes renal calcium reabsorption through the TRPV5 channel. EMBO J 2014 0.97
36 Identification and characterization of two parathyroid hormone-like molecules in zebrafish. Endocrinology 2003 0.95
37 Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice. PLoS Genet 2012 0.94
38 Fibroblast growth factor-23 and cardiac structure and function. J Am Heart Assoc 2014 0.89
39 Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death. Endocrinology 2003 0.89
40 Partial rescue of postnatal growth plate abnormalities in Ihh mutants by expression of a constitutively active PTH/PTHrP receptor. Bone 2009 0.88
41 Effect of chronic kidney disease on the healing of titanium implants. Bone 2013 0.85
42 Genetic ablation of sfrp4 in mice does not affect serum phosphate homeostasis. Endocrinology 2011 0.85
43 FGF-23 is a negative regulator of prenatal and postnatal erythropoiesis. J Biol Chem 2014 0.83
44 Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasia. FASEB J 2011 0.82
45 Long-term Fgf23 deficiency does not influence aging, glucose homeostasis, or fat metabolism in mice with a nonfunctioning vitamin D receptor. Endocrinology 2012 0.81
46 Rapidly progressive severe vascular calcification sparing the kidney allograft following warfarin initiation. Am J Kidney Dis 2010 0.79
47 Indian hedgehog controls proliferation and differentiation in skin tumorigenesis and protects against malignant progression. Cell Rep 2013 0.78
48 Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization. Endocrinology 2014 0.77