Published in J Neurochem on August 22, 2013
Trophic Mechanisms for Exercise-Induced Stress Resilience: Potential Role of Interactions between BDNF and Galanin. Front Psychiatry (2014) 0.87
Galanin mediates features of neural and behavioral stress resilience afforded by exercise. Neuropharmacology (2014) 0.82
The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2. Mol Cell Neurosci (2015) 0.75
Atf3 mutant mice show reduced axon regeneration and impaired regeneration-associated gene induction after peripheral nerve injury. Open Biol (2016) 0.75
Epigenetic profiling reveals a developmental decrease in promoter accessibility during cortical maturation in vivo. Neuroepigenetics (2016) 0.75
Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin. Brain Res (2015) 0.75
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell (1992) 28.36
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell (1995) 24.99
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci U S A (1976) 21.06
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton. EMBO J (1999) 9.76
A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature (1994) 9.18
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature (1998) 7.76
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science (1999) 7.12
Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics. Nat Cell Biol (1999) 6.18
Proteins of the ADF/cofilin family: essential regulators of actin dynamics. Annu Rev Cell Dev Biol (1999) 5.76
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J Biol Chem (1995) 4.62
The role of the Rho GTPases in neuronal development. Genes Dev (2005) 4.47
Rho GTPases in neuronal morphogenesis. Nat Rev Neurosci (2000) 4.33
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol (1994) 3.65
Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid. Mol Cell Biol (1997) 3.44
Neural plasticity after peripheral nerve injury and regeneration. Prog Neurobiol (2007) 3.05
Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site. J Biol Chem (1995) 2.74
Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron (1997) 2.60
Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci (1994) 2.44
Ins and outs of ADF/cofilin activity and regulation. Eur J Cell Biol (2008) 2.34
Inactivation of Rho signaling pathway promotes CNS axon regeneration. J Neurosci (1999) 2.13
Regulating actin-filament dynamics in vivo. Trends Biochem Sci (2000) 1.97
Actin depolymerizing factor and cofilin phosphorylation dynamics: response to signals that regulate neurite extension. Cell Motil Cytoskeleton (1998) 1.96
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2. J Cell Biol (1999) 1.96
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity. Nat Neurosci (2010) 1.82
Distribution and cellular localization of actin depolymerizing factor. J Cell Biol (1987) 1.77
Cdc42 regulates cofilin during the establishment of neuronal polarity. J Neurosci (2007) 1.73
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol Biol Cell (2005) 1.66
Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11. J Biol Chem (2003) 1.57
Isolation and characterization of a regulated form of actin depolymerizing factor. J Cell Biol (1993) 1.56
Specificity of peripheral nerve regeneration: interactions at the axon level. Prog Neurobiol (2012) 1.55
Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPases. J Neurobiol (2000) 1.51
Increase in neurite outgrowth mediated by overexpression of actin depolymerizing factor. J Neurosci (2000) 1.49
Differential intracellular signaling of the GalR1 and GalR2 galanin receptor subtypes. Biochemistry (1998) 1.45
Retracted Ubiquitination of the GTPase Rap1B by the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. EMBO J (2007) 1.42
LIM kinase and slingshot are critical for neurite extension. J Biol Chem (2007) 1.40
p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity. J Neurosci (2004) 1.37
Potent activation of RhoA by Galpha q and Gq-coupled receptors. J Biol Chem (2002) 1.35
Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci Lett (1987) 1.34
Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc Natl Acad Sci U S A (2000) 1.27
Molecular cloning of a functional human galanin receptor. Proc Natl Acad Sci U S A (1994) 1.24
Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network. Proc Natl Acad Sci U S A (2008) 1.20
Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin. J Neurosci (2004) 1.20
Cloned human and rat galanin GALR3 receptors. Pharmacology and activation of G-protein inwardly rectifying K+ channels. J Biol Chem (1998) 1.18
Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factor. J Neurobiol (2006) 1.17
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins. Oncogene (2000) 1.14
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour. J Neurochem (2006) 1.12
The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons. J Neurosci (2003) 1.11
Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes. J Biol Chem (2003) 1.10
The axotomy-induced neuropeptides galanin and pituitary adenylate cyclase-activating peptide promote axonal sprouting of primary afferent and cranial motor neurones. Eur J Neurosci (2006) 1.06
Cdc42 stimulates neurite outgrowth and formation of growth cone filopodia and lamellipodia. J Neurobiol (2000) 1.06
Independent roles of Rho-GTPases in growth cone and axonal behavior. J Neurobiol (2003) 1.06
DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis. EMBO J (2012) 1.00
Rho GTPases as regulators of morphological neuroplasticity. Ann Anat (2011) 0.98
Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly. FEBS Lett (2002) 0.95
miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway. Tumour Biol (2012) 0.95
Galanin in sensory neurons in the spinal cord. Front Neuroendocrinol (1992) 0.94
Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion. Proc Natl Acad Sci U S A (1999) 0.92
Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42. Biochemistry (2006) 0.91
Galanin and galanin-like peptide modulate neurite outgrowth via protein kinase C-mediated activation of extracellular signal-related kinase. Eur J Neurosci (2006) 0.88
Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin. Genes Dev (2012) 0.87
Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation. J Neurosci (2002) 0.87
Decreased cofilin1 expression is important for compaction during early mouse embryo development. Biochim Biophys Acta (2009) 0.85
Growth cone responses to growth and chemotropic factors. Eur J Neurosci (2008) 0.84
Neuronal polarization is impaired in mice lacking RhoE expression. J Neurochem (2012) 0.84
Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways. Exp Cell Res (2009) 0.83
Targeted disruption of the murine galanin gene. Ann N Y Acad Sci (1998) 0.81
Effects of glial cell line-derived neurotrophic factor on axonal growth and apoptosis in adult mammalian sensory neurons in vitro. Neuroscience (1998) 0.79
Transcriptional changes underlying the secretory activation phase of mammary gland development. Mol Endocrinol (2005) 1.23
VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro. Am J Pathol (2013) 1.14
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour. J Neurochem (2006) 1.12
Galanin protects against behavioral and neurochemical correlates of opiate reward. Neuropsychopharmacology (2007) 1.11
The second galanin receptor GalR2 plays a key role in neurite outgrowth from adult sensory neurons. J Neurosci (2003) 1.11
Galanin acts as a neuroprotective factor to the hippocampus. Proc Natl Acad Sci U S A (2004) 1.10
Axotomy-induced miR-21 promotes axon growth in adult dorsal root ganglion neurons. PLoS One (2011) 1.07
The neuropeptide galanin modulates behavioral and neurochemical signs of opiate withdrawal. Proc Natl Acad Sci U S A (2003) 1.07
Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior. Proc Natl Acad Sci U S A (2003) 1.05
Activation of the galanin receptor 2 (GalR2) protects the hippocampus from neuronal damage. J Neurochem (2007) 1.04
Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat. J Biol Chem (2004) 1.04
Receptor-mediated suppression of potassium currents requires colocalization within lipid rafts. Mol Pharmacol (2009) 0.99
Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy. J Neurosci (2007) 0.95
Transgenic over-expression of galanin in injured primary sensory neurons. Neuroreport (2002) 0.93
A role for galanin in human and experimental inflammatory demyelination. Proc Natl Acad Sci U S A (2009) 0.93
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake. Alcohol Clin Exp Res (2009) 0.91
Activation of the galanin receptor 2 in the periphery reverses nerve injury-induced allodynia. Mol Pain (2011) 0.90
GalR1, but not GalR2 or GalR3, levels are regulated by galanin signaling in the locus coeruleus through a cyclic AMP-dependent mechanism. J Neurochem (2005) 0.90
Neuroendocrine profiles in galanin-overexpressing and knockout mice. Neuroendocrinology (2003) 0.89
Characterization of a novel neuropathic pain model in mice. Neuroreport (2008) 0.89
The neuropeptide galanin augments lobuloalveolar development. J Biol Chem (2003) 0.85
Galanin plays a role in the conditioning lesion effect in sensory neurons. Neuroreport (2007) 0.85
Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour. J Neurochem (2008) 0.84
Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice. Endocrinology (2004) 0.83
The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel. Mol Cell Neurosci (2007) 0.83
Effect of neocortical and hippocampal amyloid deposition upon galaninergic and cholinergic neurites in AβPPswe/PS1ΔE9 mice. J Alzheimers Dis (2011) 0.82
Galanin negatively modulates opiate withdrawal via galanin receptor 1. Psychopharmacology (Berl) (2011) 0.81
Peripheral galanin receptor 2 as a target for the modulation of pain. Pain Res Treat (2012) 0.81
Osteopontin expression and function within the dorsal root ganglion. Neuroreport (2007) 0.81
Intact cutaneous C fibre afferent properties in mechanical and cold neuropathic allodynia. Eur J Pain (2009) 0.81
Endogenous galanin protects mouse hippocampal neurons against amyloid toxicity in vitro via activation of galanin receptor-2. J Alzheimers Dis (2011) 0.80
The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage. Mol Cell Neurosci (2010) 0.80
Differential roles of galanin on mechanical and cooling responses at the primary afferent nociceptor. Mol Pain (2012) 0.79
Targeted disruption of the galanin gene attenuates inflammatory responses in murine skin. J Mol Neurosci (2007) 0.79
Galanin-expression and galanin-dependent sensory neurons are not required for itch. Mol Pain (2012) 0.78
Characterisation of the nociceptive phenotype of suppressible galanin overexpressing transgenic mice. Mol Pain (2010) 0.78
Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes. Am J Med Genet B Neuropsychiatr Genet (2014) 0.77
Sudomotor function and sweat gland innervation in galanin knockout mice. Neuropeptides (2012) 0.76
The NHS academic vision: training the physicians to deliver it. Clin Med (2011) 0.75
The galanin antagonist M35 has intrinsic agonistic activity in the dorsal root ganglion. Neuroreport (2003) 0.75
Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor. Glia (2015) 0.75
The future of health research in the UK. Clin Med (2007) 0.75